Upstream Bio, Inc.
UPB- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0002022626
近 90 天，Upstream Bio, Inc. 內部人申報 0 筆公開市場買進、5 筆賣出；2026 年第 2 季末有 148 家機構在 13F 申報持有，市值合計 $3.50 億；沒有大師持有。
2025 年第 1 季 13F 持有人
Upstream Bio, Inc. 在 2025/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 79
- 較 2024 年第 4 季 +10 家
- 持有股數
- 4,628 萬
- 較 2024 年第 4 季 +422.7 萬 (+10.1%)
- 總市值
- $2.67 億
- 較 2024 年第 4 季 −$4.23 億 (−61.3%)
- 新進機構
- 24
- 另有 11 家加碼
- 清倉機構
- 14
- 另有 26 家減碼
另有 1 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 UPB 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 148 | $3.50 億 |
| 2026 年第 1 季 | 140 | $4.04 億 |
| 2025 年第 4 季 | 133 | $13.9 億 |
| 2025 年第 3 季 | 95 | $8.36 億 |
| 2025 年第 2 季 | 83 | $5.31 億 |
| 2025 年第 1 季 | 79 | $2.67 億 |
| 2024 年第 4 季 | 70 | $6.90 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2025 年第 1 季持有機構
每家機構持有 Upstream Bio, Inc. 的股數、市值與佔組合比重；股數變化跟 2024 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 7,255,859 | $4,441 萬 | 0.00% | +79,672+1.1% | 加碼 |
| OrbiMed Advisors LLC | 5,693,589 | $3,484 萬 | 0.84% | 00.0% | 不變 |
| Decheng Capital LLC | 3,285,293 | $2,011 萬 | 5.64% | 00.0% | 不變 |
| TCG Crossover Management, LLC | 2,801,763 | $1,715 萬 | 2.34% | 00.0% | 不變 |
| Enavate Sciences GP, LLC | 2,459,703 | $1,505 萬 | 11.34% | 00.0% | 不變 |
| Deep Track Capital, LP | 2,299,567 | $1,407 萬 | 0.46% | +1,299,567+130.0% | 加碼 |
| Bain Capital Life Sciences Investors, LLC | 2,295,322 | $1,405 萬 | 2.08% | 00.0% | 不變 |
| VR Adviser, LLC | 2,295,319 | $1,405 萬 | 1.20% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 2,067,146 | $1,265 萬 | 2.26% | −150,000−6.8% | 減碼 |
| Omega Fund Management, LLC | 2,036,293 | $1,246 萬 | 7.35% | 00.0% | 不變 |
| Wellington Management Group LLP | 1,313,457 | $802.6 萬 | 0.00% | −269,697−17.0% | 減碼 |
| BlackRock, Inc. | 1,185,768 | $725.7 萬 | 0.00% | +67,968+6.1% | 加碼 |
| Alliancebernstein L.P. | 1,091,186 | $667.8 萬 | 0.00% | −20,151−1.8% | 減碼 |
| Norges Bank | 969,916 | $593.6 萬 | 0.00% | −30,084−3.0% | 減碼 |
| Vanguard Group Inc | 907,026 | $555.1 萬 | 0.00% | −7,995−0.9% | 減碼 |
| Siren, L.L.C. | 788,450 | $482.5 萬 | 0.27% | −11,550−1.4% | 減碼 |
| Nantahala Capital Management, LLC | 594,971 | $364.1 萬 | 0.30% | −5,029−0.8% | 減碼 |
| Altshuler Shaham Ltd | 3,235,293 | $352.0 萬 | 0.09% | +3,235,293 | 新進 |
| Woodline Partners LP | 557,063 | $340.9 萬 | 0.02% | +30,552+5.8% | 加碼 |
| Geode Capital Management, LLC | 410,677 | $251.4 萬 | 0.00% | +47,408+13.1% | 加碼 |
| Marshall Wace, LLP | 304,963 | $186.6 萬 | 0.00% | +14,229+4.9% | 加碼 |
| Great Point Partners LLC | 300,000 | $183.6 萬 | 1.00% | 00.0% | 不變 |
| State Street Corp | 295,587 | $180.9 萬 | 0.00% | +48,400+19.6% | 加碼 |
| Parkman Healthcare Partners LLC | 233,563 | $142.9 萬 | 0.17% | +233,563 | 新進 |
| Lynx1 Capital Management LP | 219,247 | $134.2 萬 | 0.48% | −20,795−8.7% | 減碼 |
| Schonfeld Strategic Advisors LLC | 177,984 | $108.9 萬 | 0.01% | +177,984 | 新進 |
| Northern Trust Corp | 137,771 | $84.3 萬 | 0.00% | −5,950−4.1% | 減碼 |
| Charles Schwab Investment Management Inc | 132,173 | $80.9 萬 | 0.00% | −3,150−2.3% | 減碼 |
| UBS Group AG | 131,551 | $80.5 萬 | 0.00% | −29,961−18.6% | 減碼 |
| Velan Capital Investment Management LP | 107,000 | $65.5 萬 | 0.67% | +107,000 | 新進 |
| Alyeska Investment Group, L.P. | 85,000 | $52.0 萬 | 0.00% | 00.0% | 不變 |
| Millennium Management LLC | 61,796 | $37.8 萬 | 0.00% | +61,796 | 新進 |
| EcoR1 Capital, LLC | 60,000 | $36.7 萬 | 0.02% | 00.0% | 不變 |
| Morgan Stanley | 51,391 | $31.5 萬 | 0.00% | +8,228+19.1% | 加碼 |
| Alps Advisors Inc | 39,079 | $23.9 萬 | 0.00% | −4,261−9.8% | 減碼 |
| Bank of New York Mellon Corp | 36,912 | $22.6 萬 | 0.00% | −10.0% | 減碼 |
| Goldman Sachs Group Inc | 32,955 | $20.2 萬 | 0.00% | −11,535−25.9% | 減碼 |
| Barclays PLC | 24,993 | $15.3 萬 | 0.00% | −2,024−7.5% | 減碼 |
| Nuveen, LLC | 22,586 | $13.8 萬 | 0.00% | +22,586 | 新進 |
| Two Sigma Investments, LP | 21,789 | $13.3 萬 | 0.00% | +21,789 | 新進 |
| Susquehanna International Group, LLP | 21,264 | $13.0 萬 | 0.00% | +21,264 | 新進 |
| AQR Capital Management LLC | 18,822 | $11.5 萬 | 0.00% | +18,822 | 新進 |
| Citigroup Inc | 18,178 | $11.1 萬 | 0.00% | −8,326−31.4% | 減碼 |
| Invesco Ltd. | 15,315 | $9.37 萬 | 0.00% | −287−1.8% | 減碼 |
| Intech Investment Management LLC | 15,285 | $9.35 萬 | 0.00% | +15,285 | 新進 |
| Quantinno Capital Management LP | 15,225 | $9.32 萬 | 0.00% | +15,225 | 新進 |
| JPMorgan Chase & Co | 15,194 | $9.30 萬 | 0.00% | −32,598−68.2% | 減碼 |
| Deutsche Bank AG | 15,192 | $9.30 萬 | 0.00% | +341+2.3% | 加碼 |
| ADAR1 Capital Management, LLC | 15,000 | $9.18 萬 | 0.02% | +15,000 | 新進 |
| Rhumbline Advisers | 13,327 | $8.16 萬 | 0.00% | −3,394−20.3% | 減碼 |
| XTX Topco Ltd | 12,731 | $7.79 萬 | 0.00% | +12,731 | 新進 |
| MetLife Investment Management | 11,034 | $6.75 萬 | 0.00% | 00.0% | 不變 |
| Bank of America Corp | 10,531 | $6.45 萬 | 0.00% | −3,432−24.6% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 10,296 | $6.30 萬 | 0.00% | +468+4.8% | 加碼 |
| Walleye Capital LLC | 10,000 | $6.12 萬 | 0.00% | 00.0% | 不變 |
| Wells Fargo & Company | 9,250 | $5.66 萬 | 0.00% | +203+2.2% | 加碼 |
| Corebridge Financial, Inc. | 8,533 | $5.22 萬 | 0.00% | −127−1.5% | 減碼 |
| New York State Common Retirement Fund | 4,700 | $2.88 萬 | 0.00% | +4,700 | 新進 |
| Police & Firemen's Retirement System of New Jersey | 3,350 | $2.05 萬 | 0.00% | +3,350 | 新進 |
| STRS Ohio | 3,200 | $1.96 萬 | 0.00% | 00.0% | 不變 |
| Ameritas Investment Partners, Inc. | 1,822 | $1.12 萬 | 0.00% | 00.0% | 不變 |
| Legal & General Group Plc | 1,734 | $1.06 萬 | 0.00% | 00.0% | 不變 |
| CWM, LLC | 1,596 | $1.00 萬 | 0.00% | +1,596 | 新進 |
| Tower Research Capital LLC (TRC) | 1,582 | $9,682 | 0.00% | −1,264−44.4% | 減碼 |
| California State Teachers Retirement System | 1,290 | $7,895 | 0.00% | 00.0% | 不變 |
| BNP Paribas Arbitrage, SA | 939 | $5,747 | 0.00% | −572−37.9% | 減碼 |
| Royal Bank of Canada | 832 | $5,000 | 0.00% | −450−35.1% | 減碼 |
| Amalgamated Bank | 594 | $4,000 | 0.00% | 00.0% | 不變 |
| Versant Capital Management, Inc | 615 | $3,764 | 0.00% | +615 | 新進 |
| GAMMA Investing LLC | 593 | $3,629 | 0.00% | +593 | 新進 |
| US Bancorp | 562 | $3,439 | 0.00% | −1,098−66.1% | 減碼 |
| Allworth Financial LP | 185 | $1,658 | 0.00% | +185 | 新進 |
| Sterling Capital Management LLC | 137 | $838 | 0.00% | −112−45.0% | 減碼 |
| Nisa Investment Advisors, LLC | 136 | $832 | 0.00% | +136 | 新進 |
| EverSource Wealth Advisors, LLC | 135 | $826 | 0.00% | +135 | 新進 |
| Signaturefd, LLC | 90 | $551 | 0.00% | +90 | 新進 |
| UMA Financial Services, Inc. | 69 | $423 | 0.00% | +69 | 新進 |
| Principal Securities, Inc. | 12 | $197 | 0.00% | 00.0% | 不變 |
| True Wealth Design, LLC | 16 | $98 | 0.00% | +16 | 新進 |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −301,152−100.0% | 清倉 |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −180,000−100.0% | 清倉 |
| Moody Aldrich Partners LLC | 0 | $0 | 0.00% | −74,773−100.0% | 清倉 |
| Soros Fund Management LLC大師索羅斯基金管理 | 0 | $0 | 0.00% | −46,350−100.0% | 清倉 |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −45,549−100.0% | 清倉 |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −37,379−100.0% | 清倉 |
| Davidson Kempner Capital Management LP | 0 | $0 | 0.00% | −12,500−100.0% | 清倉 |
| Sandia Investment Management LP | 0 | $0 | 0.00% | −10,000−100.0% | 清倉 |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −7,590−100.0% | 清倉 |
| R Squared Ltd | 0 | $0 | 0.00% | −160−100.0% | 清倉 |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −134−100.0% | 清倉 |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −44−100.0% | 清倉 |
| Advisor Group Holdings, Inc. | 0 | $0 | 0.00% | −17−100.0% | 清倉 |
| National Bank of Canada | 0 | $0 | 0.00% | −7−100.0% | 清倉 |
| Nuveen Asset Management, LLC | – | – | – | – | 本季未申報 |