Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 208
- +19 vs. Q1 2026
- Shares held
- 299.6M
- +34.0M (+12.8%) vs. Q1 2026
- Total value
- $2.03B
- +$851.2M (+72.0%) vs. Q1 2026
- New holders
- 41
- 98 more added
- Sold out
- 22
- 41 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Prelude Capital Management, LLC | 98,346 | $669.7K | 0.05% | +98,346 | New |
| XTX Topco Ltd | 101,195 | $689.1K | 0.01% | +90,866+879.7% | Added |
| Manufacturers Life Insurance Company, The | 104,095 | $708.9K | 0.00% | +4,724+4.8% | Added |
| Engineers Gate Manager LP | 104,132 | $709.1K | 0.01% | +104,132 | New |
| Franklin Resources Inc | 106,290 | $723.8K | 0.00% | −2,109−1.9% | Reduced |
| Legal & General Group Plc | 108,207 | $736.9K | 0.00% | +3,899+3.7% | Added |
| Aquatic Capital Management LLC | 108,208 | $736.9K | 0.03% | +68,352+171.5% | Added |
| Mariner, LLC | 116,582 | $793.9K | 0.00% | +116,582 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 127,915 | $869.7K | 0.00% | +3,185+2.6% | Added |
| AQR Capital Management LLC | 128,764 | $876.9K | 0.00% | −48,545−27.4% | Reduced |
| Vanguard Asset Management, Ltd | 132,614 | $903.1K | 0.00% | +42,140+46.6% | Added |
| Persistent Asset Partners Ltd | 133,411 | $908.5K | 0.29% | +133,411 | New |
| Vanguard Global Advisers, LLC | 133,821 | $911.3K | 0.00% | +17,130+14.7% | Added |
| MetLife Investment Management | 140,846 | $959.2K | 0.00% | +20,730+17.3% | Added |
| Palumbo Wealth Management LLC | 149,173 | $1.02M | 0.22% | +2,464+1.7% | Added |
| Rafferty Asset Management, LLC | 154,706 | $1.05M | 0.00% | −145,197−48.4% | Reduced |
| Wexford Capital LP | 160,654 | $1.09M | 0.15% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 247,680 | $1.11M | 0.00% | +58,440+30.9% | Added |
| Raymond James Financial Inc | 166,042 | $1.13M | 0.00% | +144,011+653.7% | Added |
| California State Teachers Retirement System | 169,374 | $1.15M | 0.00% | +32,441+23.7% | Added |
| State of Wisconsin Investment Board | 177,089 | $1.21M | 0.00% | −86,243−32.8% | Reduced |
| Balyasny Asset Management LLC | 189,332 | $1.29M | 0.00% | +106,313+128.1% | Added |
| Chicago Partners Investment Group LLC | 222,347 | $1.30M | 0.03% | +51,596+30.2% | Added |
| Victory Capital Management Inc | 197,578 | $1.35M | 0.00% | +1,833+0.9% | Added |
| Privium Fund Management B.V. | 198,900 | $1.35M | 0.25% | +17,000+9.3% | Added |
| Price T Rowe Associates Inc | 199,494 | $1.36M | 0.00% | +40,540+25.5% | Added |
| Monashee Investment Management LLC | 200,000 | $1.36M | 2.29% | +200,000 | New |
| SG Americas Securities, LLC | 202,260 | $1.38M | 0.00% | −1,974,482−90.7% | Reduced |
| Jane Street Group, LLC | 228,355 | $1.56M | 0.00% | +228,355 | New |
| Two Sigma Investments, LP | 234,716 | $1.60M | 0.00% | −507,365−68.4% | Reduced |
| Deutsche Bank AG | 243,379 | $1.66M | 0.00% | +61,610+33.9% | Added |
| Sphera Funds Management Ltd. | 250,000 | $1.70M | 0.24% | +250,000 | New |
| Qube Research & Technologies Ltd | 259,605 | $1.77M | 0.00% | +259,605 | New |
| Ensign Peak Advisors, Inc | 262,896 | $1.79M | 0.00% | −12,215−4.4% | Reduced |
| Invesco Ltd. | 264,379 | $1.80M | 0.00% | −103,642−28.2% | Reduced |
| UBS Asset Management Americas Inc | 272,600 | $1.86M | 0.00% | +6,805+2.6% | Added |
| Alps Advisors Inc | 290,543 | $1.98M | 0.01% | +67,557+30.3% | Added |
| Rhumbline Advisers | 299,975 | $2.04M | 0.00% | +41,445+16.0% | Added |
| Citigroup Inc | 306,907 | $2.09M | 0.00% | +249,827+437.7% | Added |
| Jefferies Financial Group Inc. | 328,800 | $2.24M | 0.02% | −150,200−31.4% | Reduced |
| Wells Fargo & Company | 333,314 | $2.27M | 0.00% | +149,980+81.8% | Added |
| Moore Capital Management, LP | 358,374 | $2.44M | 0.06% | +29,543+9.0% | Added |
| Swiss National Bank | 369,000 | $2.51M | 0.00% | +100,200+37.3% | Added |
| Trexquant Investment LP | 379,577 | $2.58M | 0.02% | +379,577 | New |
| Voya Investment Management LLC | 425,363 | $2.90M | 0.00% | −86,620−16.9% | Reduced |
| Dimensional Fund Advisors LP | 464,771 | $3.16M | 0.00% | −25,701−5.2% | Reduced |
| Polen Capital Management LLC | 489,219 | $3.33M | 0.03% | +169,471+53.0% | Added |
| Burkehill Global Management, LP | 500,000 | $3.40M | 0.12% | +500,000 | New |
| Ghisallo Capital Management LLC | 505,000 | $3.44M | 0.07% | +505,000 | New |
| Holocene Advisors, LP | 510,000 | $3.47M | 0.01% | +510,000 | New |
| Woodline Partners LP | 513,828 | $3.50M | 0.01% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 519,120 | $3.54M | 0.10% | +127,644+32.6% | Added |
| Diadema Partners LP | 522,619 | $3.56M | 1.26% | +522,619 | New |
| Adage Capital Partners GP, L.L.C. | 553,000 | $3.77M | 0.01% | +553,000 | New |
| Nuveen, LLC | 555,693 | $3.78M | 0.00% | +6,540+1.2% | Added |
| Acuta Capital Partners, LLC | 561,808 | $3.83M | 2.67% | +122,344+27.8% | Added |
| Squarepoint Ops LLC | 569,269 | $3.88M | 0.01% | +158,987+38.8% | Added |
| Affinity Wealth Management LLC | 576,808 | $3.93M | 0.51% | +576,808 | New |
| UBS Group AG | 588,427 | $4.01M | 0.00% | +70,729+13.7% | Added |
| Panagora Asset Management Inc | 590,387 | $4.02M | 0.01% | +408,223+224.1% | Added |
| BNP Paribas Arbitrage, SA | 640,035 | $4.36M | 0.00% | +519,835+432.5% | Added |
| Bank of New York Mellon Corp | 697,971 | $4.75M | 0.00% | +89,848+14.8% | Added |
| Sands Capital Ventures, LLC | 724,873 | $4.94M | 0.80% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 766,282 | $5.16M | 0.00% | +11,500+1.5% | Added |
| First Trust Advisors LP | 791,169 | $5.39M | 0.00% | +791,169 | New |
| Quantum Private Wealth, LLC | 812,027 | $5.53M | 1.42% | −37,185−4.4% | Reduced |
| Granahan Investment Management Inc | 1,305,177 | $8.89M | 0.32% | +421,936+47.8% | Added |
| Bank of America Corp | 1,372,845 | $9.35M | 0.00% | −304,201−18.1% | Reduced |
| Palo Alto Investors LP | 1,391,382 | $9.48M | 1.31% | 00.0% | Unchanged |
| Seven Fleet Capital Management LP | 1,504,400 | $9.94M | 1.64% | +878,692+140.4% | Added |
| Heights Capital Management, Inc | 1,500,000 | $10.2M | 2.36% | +1,500,000 | New |
| Citadel Advisors LLC | 1,535,287 | $10.5M | 0.01% | +1,124,152+273.4% | Added |
| Barclays PLC | 1,630,659 | $11.1M | 0.00% | −1,181,351−42.0% | Reduced |
| Affinity Asset Advisors, LLC | 1,750,000 | $11.9M | 0.58% | +750,000+75.0% | Added |
| B Group, Inc. | 1,800,556 | $12.3M | 6.96% | 00.0% | Unchanged |
| Vanguard Fiduciary Trust Co | 1,896,474 | $12.9M | 0.00% | +366,013+23.9% | Added |
| Rice Hall James & Associates, LLC | 1,992,229 | $13.6M | 0.66% | +47,558+2.4% | Added |
| OrbiMed Advisors LLC | 2,000,000 | $13.6M | 0.26% | +2,000,000 | New |
| Millennium Management LLC | 2,126,838 | $14.5M | 0.01% | −1,154,982−35.2% | Reduced |
| Charles Schwab Investment Management Inc | 2,200,695 | $15.0M | 0.00% | +392,096+21.7% | Added |
| Northern Trust Corp | 2,226,210 | $15.2M | 0.00% | +411,892+22.7% | Added |
| Norges Bank | 2,233,600 | $15.2M | 0.00% | +2,233,600 | New |
| Farallon Capital Management, L.L.C. | 2,250,000 | $15.3M | 0.09% | +2,250,000 | New |
| Standard Life Aberdeen plc | 2,327,152 | $15.8M | 0.02% | +1,306,089+127.9% | Added |
| Pictet Asset Management Holding SA | 2,770,701 | $18.9M | 0.02% | +2,751,383+14,242.6% | Added |
| ADAR1 Capital Management, LLC | 3,040,466 | $20.7M | 0.97% | +61,037+2.0% | Added |
| Vanguard Portfolio Management LLC | 3,140,009 | $21.4M | 0.00% | +1,117,511+55.3% | Added |
| Casdin Capital, LLC | 3,250,000 | $22.1M | 1.11% | 00.0% | Unchanged |
| Healthcare of Ontario Pension Plan Trust Fund | 3,885,501 | $26.5M | 0.04% | +1,002,200+34.8% | Added |
| Wellington Management Group LLP | 3,975,605 | $27.1M | 0.00% | +3,349,244+534.7% | Added |
| Baker Bros. Advisors LP | 4,004,756 | $27.3M | 0.14% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 4,398,652 | $30.0M | 0.02% | −28,649−0.6% | Reduced |
| MPM Oncology Impact Management LP | 4,500,000 | $30.6M | 1.87% | +4,500,000 | New |
| Polar Capital Holdings Plc | 5,117,133 | $34.8M | 0.10% | −537,207−9.5% | Reduced |
| Geode Capital Management, LLC | 6,560,394 | $44.7M | 0.00% | +1,028,439+18.6% | Added |
| Octagon Capital Advisors LP | 9,693,244 | $66.0M | 6.06% | +833,333+9.4% | Added |
| Siren, L.L.C. | 9,846,579 | $67.1M | 1.36% | +1,016,666+11.5% | Added |
| State Street Corp | 11,421,920 | $77.8M | 0.00% | +212,842+1.9% | Added |
| Vanguard Capital Management LLC | 12,478,595 | $85.0M | 0.00% | +2,247,093+22.0% | Added |
| FMR LLC | 13,336,413 | $90.8M | 0.00% | −984,842−6.9% | Reduced |