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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Taysha Gene Therapies, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
191
+1 vs. Q4 2025
Shares held
265.6M
+12.1M (+4.8%) vs. Q4 2025
Total value
$1.18B
−$211.2M (−15.1%) vs. Q4 2025
New holders
35
69 more added
Sold out
34
49 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 191 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ1 2026: $1.18B
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q4 2025.

Institutions holding TSHA in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Nomura Holdings Inc0$00.00%−259,339−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−208,016−100.0%Sold out
StemPoint Capital LP0$00.00%−182,130−100.0%Sold out
Jane Street Group, LLC0$00.00%−163,146−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−139,581−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−68,900−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−56,595−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−54,785−100.0%Sold out
Redwood Wealth Management Group, LLC0$00.00%−44,700−100.0%Sold out
Group One Trading, L.P.0$00.00%−44,195−100.0%Sold out
Axq Capital, LP0$00.00%−37,804−100.0%Sold out
Leonteq Securities AG0$00.00%−27,999−100.0%Sold out
Mangrove Partners0$00.00%−20,546−100.0%Sold out
Simplex Trading, LLC0$00.00%−19,782−100.0%Sold out
Captrust Financial Advisors0$00.00%−15,113−100.0%Sold out
Mackenzie Financial Corp0$00.00%−13,308−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−10,773−100.0%Sold out
Amalgamated Bank0$00.00%−6,939−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−691−100.0%Sold out
Bare Financial Services, Inc0$00.00%−85−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−49−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−21−100.0%Sold out
Tradewinds Capital Management, LLC0$00.00%−20−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−8−100.0%Sold out
Hughes Financial Services, LLC0$00.00%−4−100.0%Sold out
Vanguard Group Inc––––Not filed
Norges Bank––––Not filed
Oracle Investment Management Inc––––Not filed
Militia Capital Partners, LP––––Not filed
CIBC World Markets Corp––––Not filed