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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2026

Institutional positions in Prime Medicine, Inc. as of Sep 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Q3 2026 data is still coming in (13F filing deadline: Nov 16, 2026), so these numbers are incomplete.

Institutional holders
0
−1 vs. Q2 2026
Shares held
0
−134 (−100.0%) vs. Q2 2026
Total value
$0
−$494 (−100.0%) vs. Q2 2026
New holders
0
0 more added
Sold out
1
0 more reduced

186 institutions that held it in Q2 2026 haven't filed for Q3 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holders
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value held
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2026

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q2 2026.

Institutions holding PRME in Q3 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Police & Firemen's Retirement System of New Jersey––––Not filed
Oppenheimer & Co Inc––––Not filed
Raymond James Financial Inc––––Not filed
SEI Investments Co––––Not filed
China Universal Asset Management Co., Ltd.––––Not filed
Arizona State Retirement System––––Not filed
Envestnet Asset Management Inc––––Not filed
Manufacturers Life Insurance Company, The––––Not filed
Vanguard Investments Australia, Ltd.––––Not filed
Blue Bell Private Wealth Management, LLC––––Not filed
Mariner, LLC––––Not filed
Abacus Planning Group, Inc.––––Not filed
Intech Investment Management LLC––––Not filed
Creative Planning––––Not filed
Magnetar Financial LLC––––Not filed
E Fund Management Co., Ltd.––––Not filed
Schonfeld Strategic Advisors LLC––––Not filed
Voya Investment Management LLC––––Not filed
JustInvest LLC––––Not filed
Shelton Wealth Management, LLC––––Not filed
CIBC World Markets Inc.––––Not filed
Graham Capital Management, L.P.––––Not filed
KLP Kapitalforvaltning AS––––Not filed
ProShare Advisors LLC––––Not filed
Zurcher Kantonalbank (Zurich Cantonalbank)––––Not filed
Cambridge Investment Research Advisors, Inc.––––Not filed
Ieq Capital, LLC––––Not filed
Wealth Enhancement Advisory Services, LLC––––Not filed
Levin Capital Strategies, L.P.––––Not filed
Prudential Financial Inc––––Not filed
Thompson Davis & Co., Inc.––––Not filed
Sanctuary Advisors, LLC––––Not filed
JTC Employer Solutions Trusteee Ltd––––Not filed
DRW Securities, LLC––––Not filed
Prime Capital Investment Advisors, LLC––––Not filed
Brevan Howard Capital Management LP––––Not filed
State of Wisconsin Investment Board––––Not filed
Pictet Asset Management Holding SA––––Not filed
Sequoia Financial Advisors, LLC––––Not filed
Teacher Retirement System of Texas––––Not filed
Wealthfront Advisers LLC––––Not filed
Syon Capital LLC––––Not filed
Victory Capital Management Inc––––Not filed
Benjamin Edwards Inc––––Not filed
NBC Securities, Inc.––––Not filed
Kingsview Wealth Management, LLC––––Not filed
Forum Financial Management, LP––––Not filed
Federation des caisses Desjardins du Quebec––––Not filed
Advisor Group Holdings, Inc.––––Not filed
New York State Common Retirement Fund––––Not filed
Ameritas Investment Partners, Inc.––––Not filed
Mirae Asset Global Investments Co., Ltd.––––Not filed
Tower Research Capital LLC (TRC)––––Not filed
Royal Bank of Canada––––Not filed
Signaturefd, LLC––––Not filed
Glen Eagle Advisors, LLC––––Not filed
Nisa Investment Advisors, LLC––––Not filed
GF Fund Management Co. Ltd.––––Not filed
Owl Creek Wealth Partners LLC––––Not filed
Pacer Advisors, Inc.––––Not filed
Caitong International Asset Management Co., Ltd––––Not filed
EverSource Wealth Advisors, LLC––––Not filed
Allworth Financial LP––––Not filed
GWM Advisors LLC––––Not filed
SRS Capital Advisors, Inc.––––Not filed
GAMMA Investing LLC––––Not filed
SBI Securities Co., Ltd.––––Not filed
Quarry LP––––Not filed
Sterling Capital Management LLC––––Not filed
Fairman Group, LLC––––Not filed
Rothschild Investment LLC––––Not filed
The PNC Financial Services Group, Inc.––––Not filed
Fortitude Family Office, LLC––––Not filed
Basecamp Wealth Advisors LLC––––Not filed
Parkside Financial Bank & Trust––––Not filed
Optiver Holding B.V.––––Not filed
Sachetta, LLC––––Not filed
Harbour Investments, Inc.––––Not filed
Farther Finance Advisors, LLC––––Not filed
Natixis––––Not filed
Newbridge Financial Services Group, Inc.––––Not filed
National Bank of Canada––––Not filed
Essential Partners LLC––––Not filed
IFP Advisors, Inc––––Not filed
Clearstead Advisors, LLC––––Not filed
Wealth Enhancement Trust Services, Inc.––––Not filed
Covestor Ltd––––Not filed