Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2023
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 79
- +3 vs. Q1 2023
- Shares held
- 46.1M
- +4.39M (+10.5%) vs. Q1 2023
- Total value
- $675.7M
- +$163.6M (+32.0%) vs. Q1 2023
- New holders
- 16
- 36 more added
- Sold out
- 13
- 13 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 15 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 9 | $0 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 33 | $483 | 0.00% | +33 | New |
| Massmutual Trust Co FSB | 34 | $498 | 0.00% | +34 | New |
| Benjamin Edwards Inc | 321 | $5.00K | 0.00% | +139+76.4% | Added |
| US Bancorp | 346 | $5.07K | 0.00% | +346 | New |
| Endurance Wealth Management, Inc. | 500 | $8.00K | 0.00% | 00.0% | Unchanged |
| Chelsea Counsel Co | 600 | $8.79K | 0.00% | 00.0% | Unchanged |
| First Horizon Advisors, Inc. | 1,555 | $22.8K | 0.00% | −143−8.4% | Reduced |
| Lazard Asset Management LLC | 1,604 | $23.0K | 0.00% | +57+3.7% | Added |
| Metropolitan Life Insurance Co | 2,203 | $32.3K | 0.00% | +1,485+206.8% | Added |
| Tower Research Capital LLC (TRC) | 3,143 | $46.0K | 0.00% | −82−2.5% | Reduced |
| Ameritas Investment Partners, Inc. | 3,267 | $47.9K | 0.00% | +2,436+293.1% | Added |
| Royal Bank of Canada | 3,579 | $53.0K | 0.00% | +2,989+506.6% | Added |
| Amalgamated Bank | 4,752 | $70.0K | 0.00% | +3,488+275.9% | Added |
| Legal & General Group Plc | 4,791 | $70.2K | 0.00% | +1,364+39.8% | Added |
| ORG Partners LLC | 5,270 | $76.4K | 0.01% | +5,270 | New |
| Advisor Group Holdings, Inc. | 6,403 | $93.8K | 0.00% | −28−0.4% | Reduced |
| Barclays PLC | 7,879 | $115.4K | 0.00% | +2,543+47.7% | Added |
| Penserra Capital Management LLC | 8,107 | $118.0K | 0.00% | +1,107+15.8% | Added |
| Sandia Investment Management LP | 10,000 | $146.5K | 0.05% | 00.0% | Unchanged |
| Brown Brothers Harriman & Co | 10,065 | $147.5K | 0.00% | +10,065 | New |
| State Board of Administration of Florida Retirement System | 11,230 | $164.5K | 0.00% | +11,230 | New |
| Allspring Global Investments Holdings, LLC | 11,441 | $167.6K | 0.00% | +10,290+894.0% | Added |
| Susquehanna International Group, LLP | 12,254 | $179.5K | 0.00% | +12,254 | New |
| Green Alpha Advisors, LLC | 12,386 | $181.5K | 0.12% | +12,386 | New |
| California State Teachers Retirement System | 13,159 | $192.8K | 0.00% | −7,808−37.2% | Reduced |
| Citigroup Inc | 14,161 | $207.5K | 0.00% | +5,302+59.8% | Added |
| Red Lighthouse Investment Management, LLC | 14,950 | $219.0K | 0.10% | 00.0% | Unchanged |
| Oppenheimer & Co Inc | 15,385 | $225.4K | 0.00% | +267+1.8% | Added |
| Voya Investment Management LLC | 15,743 | $230.6K | 0.00% | +15,743 | New |
| New York State Common Retirement Fund | 15,984 | $234.2K | 0.00% | +8,191+105.1% | Added |
| Clarius Group, LLC | 16,080 | $235.6K | 0.02% | 00.0% | Unchanged |
| Wells Fargo & Company | 16,297 | $238.8K | 0.00% | +14,361+741.8% | Added |
| Deutsche Bank AG | 17,812 | $260.9K | 0.00% | +6,952+64.0% | Added |
| Principal Financial Group Inc | 18,029 | $264.1K | 0.00% | +18,029 | New |
| Mirae Asset Global Investments Co., Ltd. | 18,871 | $276.5K | 0.00% | +18,871 | New |
| American International Group, Inc. | 19,040 | $278.9K | 0.00% | +13,953+274.3% | Added |
| Levin Capital Strategies, L.P. | 20,000 | $293.0K | 0.03% | +20,000 | New |
| HighTower Advisors, LLC | 21,322 | $310.0K | 0.00% | +21,322 | New |
| MetLife Investment Management | 21,262 | $311.5K | 0.00% | +15,171+249.1% | Added |
| Alliancebernstein L.P. | 26,540 | $388.8K | 0.00% | +26,540 | New |
| JPMorgan Chase & Co | 30,672 | $449.3K | 0.00% | +17,775+137.8% | Added |
| Brandywine Managers, LLC | 32,977 | $483.1K | 0.32% | 00.0% | Unchanged |
| Rhumbline Advisers | 47,063 | $689.5K | 0.00% | +47,063 | New |
| Laurion Capital Management LP | 55,888 | $818.8K | 0.04% | −4,112−6.9% | Reduced |
| Morgan Stanley | 57,929 | $848.7K | 0.00% | +24,544+73.5% | Added |
| Manufacturers Life Insurance Company, The | 58,401 | $855.6K | 0.00% | +12,770+28.0% | Added |
| TD Asset Management Inc | 67,071 | $982.6K | 0.00% | +43,149+180.4% | Added |
| UBS Group AG | 99,039 | $1.45M | 0.00% | +94,104+1,906.9% | Added |
| Bank of New York Mellon Corp | 103,213 | $1.51M | 0.00% | +73,145+243.3% | Added |
| Nuveen Asset Management, LLC | 123,195 | $1.80M | 0.00% | +109,067+772.0% | Added |
| Charles Schwab Investment Management Inc | 141,144 | $2.07M | 0.00% | +67,717+92.2% | Added |
| Bank of America Corp | 147,515 | $2.16M | 0.00% | −2,752−1.8% | Reduced |
| Ensign Peak Advisors, Inc | 150,000 | $2.20M | 0.00% | 00.0% | Unchanged |
| Greenwich Wealth Management LLC | 208,000 | $3.05M | 0.32% | −141,000−40.4% | Reduced |
| Millennium Management LLC | 256,560 | $3.76M | 0.00% | +245,801+2,284.6% | Added |
| Northern Trust Corp | 282,431 | $4.14M | 0.00% | +192,352+213.5% | Added |
| Casdin Capital, LLC | 367,175 | $5.38M | 0.47% | −367,175−50.0% | Reduced |
| Jane Street Group, LLC | 397,004 | $5.82M | 0.01% | +397,004 | New |
| Moore Capital Management, LP | 446,733 | $6.54M | 0.16% | −53,267−10.7% | Reduced |
| Samsara BioCapital, LLC | 470,304 | $6.89M | 1.21% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 540,308 | $7.92M | 0.00% | +299,963+124.8% | Added |
| Janus Henderson Group PLC | 564,854 | $8.27M | 0.01% | +550,763+3,908.6% | Added |
| EcoR1 Capital, LLC | 600,000 | $8.79M | 0.23% | 00.0% | Unchanged |
| State Street Corp | 605,199 | $8.87M | 0.00% | +415,771+219.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $13.0M | 0.28% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,028,466 | $15.1M | 0.09% | 00.0% | Unchanged |
| Redmile Group, LLC | 1,324,350 | $19.4M | 0.74% | −668,493−33.5% | Reduced |
| MWG Management Limited | 1,792,210 | $26.3M | 15.88% | −43,666−2.4% | Reduced |
| FIL Ltd | 1,805,558 | $26.5M | 0.03% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 2,333,831 | $34.2M | 0.00% | +1,430,090+158.2% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,449,199 | $35.9M | 0.24% | +526,922+27.4% | Added |
| BlackRock Inc. | 2,889,216 | $42.3M | 0.00% | +1,375,093+90.8% | Added |
| Nikko Asset Management Americas, Inc. | 3,064,616 | $44.8M | 0.47% | +2,065,283+206.7% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 3,063,751 | $44.9M | 0.03% | +2,066,179+207.1% | Added |
| Vanguard Group Inc | 3,334,483 | $48.9M | 0.00% | +2,450,037+277.0% | Added |
| FMR LLC | 4,039,219 | $59.2M | 0.00% | −4,477,910−52.6% | Reduced |
| Alphabet Inc. | 11,862,498 | $173.8M | 9.34% | −1,422,190−10.7% | Reduced |
| Cormorant Asset Management, LP | 0 | $0 | 0.00% | −734,350−100.0% | Sold out |
| Wexford Capital LP | 0 | $0 | 0.00% | −153,705−100.0% | Sold out |
| OUP Management Co., LLC | 0 | $0 | 0.00% | −121,255−100.0% | Sold out |
| Swiss National Bank | 0 | $0 | 0.00% | −41,900−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −32,500−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −32,197−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −19,663−100.0% | Sold out |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −17,999−100.0% | Sold out |
| Credit Suisse AG | 0 | $0 | 0.00% | −14,705−100.0% | Sold out |
| Capstone Investment Advisors, LLC | 0 | $0 | 0.00% | −14,551−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −2,400−100.0% | Sold out |
| TCI Wealth Advisors, Inc. | 0 | $0 | 0.00% | −231−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −45−100.0% | Sold out |