Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Prime Medicine, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 76
- +11 vs. Q4 2022
- Shares held
- 41.7M
- +420.4K (+1.0%) vs. Q4 2022
- Total value
- $512.1M
- −$255.6M (−33.3%) vs. Q4 2022
- New holders
- 18
- 29 more added
- Sold out
- 7
- 6 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Endurance Wealth Management, Inc. | 500 | $0 | 0.00% | +500 | New |
| CWM, LLC | 15 | $0 | 0.00% | +15 | New |
| Covestor Ltd | 9 | $0 | 0.00% | +9 | New |
| Federated Hermes, Inc. | 45 | $554 | 0.00% | +45 | New |
| Benjamin Edwards Inc | 182 | $2.00K | 0.00% | +35+23.8% | Added |
| TCI Wealth Advisors, Inc. | 231 | $2.84K | 0.00% | +231 | New |
| Royal Bank of Canada | 590 | $7.00K | 0.00% | −957−61.9% | Reduced |
| Chelsea Counsel Co | 600 | $7.38K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 718 | $8.83K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 831 | $10.2K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 1,151 | $14.2K | 0.00% | +1,151 | New |
| Amalgamated Bank | 1,264 | $16.0K | 0.00% | −303−19.3% | Reduced |
| Lazard Asset Management LLC | 1,547 | $18.0K | 0.00% | +1,547 | New |
| First Horizon Advisors, Inc. | 1,698 | $20.9K | 0.00% | −115−6.3% | Reduced |
| Wells Fargo & Company | 1,936 | $23.8K | 0.00% | +1,936 | New |
| STRS Ohio | 2,400 | $29.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 3,225 | $40.0K | 0.00% | +2,852+764.6% | Added |
| Legal & General Group Plc | 3,427 | $42.2K | 0.00% | +2,502+270.5% | Added |
| UBS Group AG | 4,935 | $60.7K | 0.00% | +3,726+308.2% | Added |
| American International Group, Inc. | 5,087 | $62.6K | 0.00% | +178+3.6% | Added |
| Barclays PLC | 5,336 | $65.6K | 0.00% | +2,549+91.5% | Added |
| MetLife Investment Management | 6,091 | $74.9K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 6,431 | $79.1K | 0.00% | +402+6.7% | Added |
| Penserra Capital Management LLC | 7,000 | $86.0K | 0.00% | −570−7.5% | Reduced |
| New York State Common Retirement Fund | 7,793 | $95.9K | 0.00% | +2,793+55.9% | Added |
| Citigroup Inc | 8,859 | $109.0K | 0.00% | +5,272+147.0% | Added |
| Sandia Investment Management LP | 10,000 | $123.0K | 0.02% | 00.0% | Unchanged |
| Millennium Management LLC | 10,759 | $132.0K | 0.00% | +10,759 | New |
| Deutsche Bank AG | 10,860 | $133.6K | 0.00% | +6,387+142.8% | Added |
| JPMorgan Chase & Co | 12,897 | $159.0K | 0.00% | +3,023+30.6% | Added |
| Janus Henderson Group PLC | 14,091 | $173.1K | 0.00% | +14,091 | New |
| Nuveen Asset Management, LLC | 14,128 | $174.0K | 0.00% | 00.0% | Unchanged |
| Capstone Investment Advisors, LLC | 14,551 | $179.0K | 0.01% | +14,551 | New |
| Credit Suisse AG | 14,705 | $180.9K | 0.00% | +13,905+1,738.1% | Added |
| Red Lighthouse Investment Management, LLC | 14,950 | $183.9K | 0.09% | +14,950 | New |
| Oppenheimer & Co Inc | 15,118 | $186.0K | 0.00% | +1,106+7.9% | Added |
| Clarius Group, LLC | 16,080 | $197.8K | 0.02% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 17,999 | $221.4K | 0.00% | +17,999 | New |
| Cubist Systematic Strategies, LLC | 19,663 | $241.9K | 0.00% | +18,539+1,649.4% | Added |
| California State Teachers Retirement System | 20,967 | $257.9K | 0.00% | +16,823+406.0% | Added |
| TD Asset Management Inc | 23,922 | $294.2K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 30,068 | $369.8K | 0.00% | +1,052+3.6% | Added |
| Panagora Asset Management Inc | 32,197 | $396.0K | 0.00% | +32,197 | New |
| Jump Financial, LLC | 32,500 | $399.8K | 0.02% | +32,500 | New |
| Brandywine Managers, LLC | 32,977 | $405.6K | 0.29% | 00.0% | Unchanged |
| Morgan Stanley | 33,385 | $410.6K | 0.00% | +12,996+63.7% | Added |
| Swiss National Bank | 41,900 | $515.4K | 0.00% | +41,900 | New |
| Manufacturers Life Insurance Company, The | 45,631 | $561.3K | 0.00% | +642+1.4% | Added |
| Laurion Capital Management LP | 60,000 | $738.0K | 0.03% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 73,427 | $903.2K | 0.00% | +2,243+3.2% | Added |
| Northern Trust Corp | 90,079 | $1.11M | 0.00% | +6,533+7.8% | Added |
| OUP Management Co., LLC | 121,255 | $1.49M | 2.98% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 150,000 | $1.84M | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 150,267 | $1.85M | 0.00% | +102,908+217.3% | Added |
| Wexford Capital LP | 153,705 | $1.89M | 0.39% | +153,705 | New |
| State Street Corp | 189,428 | $2.33M | 0.00% | +74,582+64.9% | Added |
| Geode Capital Management, LLC | 240,345 | $2.96M | 0.00% | +6,050+2.6% | Added |
| Greenwich Wealth Management LLC | 349,000 | $4.29M | 0.47% | +349,000 | New |
| Samsara BioCapital, LLC | 470,304 | $5.78M | 1.20% | 00.0% | Unchanged |
| Moore Capital Management, LP | 500,000 | $6.15M | 0.19% | 00.0% | Unchanged |
| EcoR1 Capital, LLC | 600,000 | $7.38M | 0.24% | 00.0% | Unchanged |
| Casdin Capital, LLC | 734,350 | $9.03M | 0.75% | 00.0% | Unchanged |
| Cormorant Asset Management, LP | 734,350 | $9.03M | 0.59% | 00.0% | Unchanged |
| Vanguard Group Inc | 884,446 | $10.9M | 0.00% | +11,923+1.4% | Added |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $10.9M | 0.24% | 00.0% | Unchanged |
| Nikko Asset Management Americas, Inc. | 999,333 | $11.0M | 0.13% | +511,107+104.7% | Added |
| Price T Rowe Associates Inc | 903,741 | $11.1M | 0.00% | −1,474,841−62.0% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 997,572 | $12.3M | 0.01% | +509,346+104.3% | Added |
| Baker Bros. Advisors LP | 1,028,466 | $12.7M | 0.07% | 00.0% | Unchanged |
| BlackRock Inc. | 1,514,123 | $18.6M | 0.00% | +26,277+1.8% | Added |
| FIL Ltd | 1,805,558 | $22.2M | 0.03% | 00.0% | Unchanged |
| MWG Management Limited | 1,835,876 | $22.6M | 15.90% | 00.0% | Unchanged |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,922,277 | $23.6M | 0.16% | +282,293+17.2% | Added |
| Redmile Group, LLC | 1,992,843 | $24.5M | 1.06% | −216,507−9.8% | Reduced |
| FMR LLC | 8,517,129 | $104.8M | 0.01% | +54,083+0.6% | Added |
| Alphabet Inc. | 13,284,688 | $163.4M | 9.06% | 00.0% | Unchanged |
| Caas Capital Management LP | 0 | $0 | 0.00% | −89,331−100.0% | Sold out |
| Ghisallo Capital Management LLC | 0 | $0 | 0.00% | −70,000−100.0% | Sold out |
| Point72 Middle East FZE | 0 | $0 | 0.00% | −37,609−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −17,760−100.0% | Sold out |
| Levin Capital Strategies, L.P. | 0 | $0 | 0.00% | −10,585−100.0% | Sold out |
| Leonteq Securities AG | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Alpha Paradigm Partners, LLC | – | – | – | – | Not filed |