Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Prime Medicine, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 66
- +66 vs. Q3 2022
- Shares held
- 41.3M
- +41.3M vs. Q3 2022
- Total value
- $767.8M
- +$767.8M vs. Q3 2022
- New holders
- 66
- 0 more added
- Sold out
- 0
- 0 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Benjamin Edwards Inc | 147 | $3.00K | 0.00% | +147 | New |
| Leonteq Securities AG | 200 | $3.72K | 0.00% | +200 | New |
| Tower Research Capital LLC (TRC) | 373 | $7.00K | 0.00% | +373 | New |
| Chelsea Counsel Co | 600 | $11.1K | 0.01% | +600 | New |
| Metropolitan Life Insurance Co | 718 | $13.3K | 0.00% | +718 | New |
| Ameritas Investment Partners, Inc. | 831 | $13.9K | 0.00% | +831 | New |
| Credit Suisse AG | 800 | $14.9K | 0.00% | +800 | New |
| Legal & General Group Plc | 925 | $17.1K | 0.00% | +925 | New |
| Cubist Systematic Strategies, LLC | 1,124 | $20.9K | 0.00% | +1,124 | New |
| UBS Group AG | 1,209 | $22.5K | 0.00% | +1,209 | New |
| Royal Bank of Canada | 1,547 | $28.0K | 0.00% | +1,547 | New |
| Amalgamated Bank | 1,567 | $29.0K | 0.00% | +1,567 | New |
| First Horizon Advisors, Inc. | 1,813 | $33.7K | 0.00% | +1,813 | New |
| STRS Ohio | 2,400 | $44.0K | 0.00% | +2,400 | New |
| Barclays PLC | 2,787 | $51.8K | 0.00% | +2,787 | New |
| Citigroup Inc | 3,587 | $66.6K | 0.00% | +3,587 | New |
| Alpha Paradigm Partners, LLC | 3,895 | $72.0K | 0.03% | +3,895 | New |
| California State Teachers Retirement System | 4,144 | $77.0K | 0.00% | +4,144 | New |
| Deutsche Bank AG | 4,473 | $83.1K | 0.00% | +4,473 | New |
| American International Group, Inc. | 4,909 | $91.2K | 0.00% | +4,909 | New |
| New York State Common Retirement Fund | 5,000 | $92.9K | 0.00% | +5,000 | New |
| Advisor Group Holdings, Inc. | 6,029 | $112.4K | 0.00% | +6,029 | New |
| MetLife Investment Management | 6,091 | $113.2K | 0.00% | +6,091 | New |
| Penserra Capital Management LLC | 7,570 | $140.0K | 0.00% | +7,570 | New |
| JPMorgan Chase & Co | 9,874 | $184.0K | 0.00% | +9,874 | New |
| Sandia Investment Management LP | 10,000 | $185.8K | 0.03% | +10,000 | New |
| Levin Capital Strategies, L.P. | 10,585 | $196.7K | 0.03% | +10,585 | New |
| Oppenheimer & Co Inc | 14,012 | $260.3K | 0.01% | +14,012 | New |
| Nuveen Asset Management, LLC | 14,128 | $262.0K | 0.00% | +14,128 | New |
| Clarius Group, LLC | 16,080 | $299.0K | 0.03% | +16,080 | New |
| LMR Partners LLP | 17,760 | $330.0K | 0.01% | +17,760 | New |
| Morgan Stanley | 20,389 | $378.8K | 0.00% | +20,389 | New |
| TD Asset Management Inc | 23,922 | $444.5K | 0.00% | +23,922 | New |
| Bank of New York Mellon Corp | 29,016 | $539.1K | 0.00% | +29,016 | New |
| Walleye Capital LLC | 30,000 | $557.4K | 0.01% | +30,000 | New |
| Brandywine Managers, LLC | 32,977 | $612.7K | 2.14% | +32,977 | New |
| Point72 Middle East FZE | 37,609 | $698.8K | 0.05% | +37,609 | New |
| Bank of America Corp | 47,359 | $879.9K | 0.00% | +47,359 | New |
| Manufacturers Life Insurance Company, The | 44,989 | $887.5K | 0.00% | +44,989 | New |
| Laurion Capital Management LP | 60,000 | $1.11M | 0.03% | +60,000 | New |
| Ghisallo Capital Management LLC | 70,000 | $1.30M | 0.23% | +70,000 | New |
| Charles Schwab Investment Management Inc | 71,184 | $1.32M | 0.00% | +71,184 | New |
| Northern Trust Corp | 83,546 | $1.55M | 0.00% | +83,546 | New |
| Caas Capital Management LP | 89,331 | $1.66M | 0.32% | +89,331 | New |
| State Street Corp | 114,846 | $2.13M | 0.00% | +114,846 | New |
| OUP Management Co., LLC | 121,255 | $2.25M | 3.68% | +121,255 | New |
| Ensign Peak Advisors, Inc | 150,000 | $2.79M | 0.01% | +150,000 | New |
| Geode Capital Management, LLC | 234,295 | $4.35M | 0.00% | +234,295 | New |
| Samsara BioCapital, LLC | 470,304 | $8.74M | 1.88% | +470,304 | New |
| Nikko Asset Management Americas, Inc. | 488,226 | $9.04M | 0.13% | +488,226 | New |
| Sumitomo Mitsui Trust Holdings, Inc. | 488,226 | $9.07M | 0.01% | +488,226 | New |
| Moore Capital Management, LP | 500,000 | $9.29M | 0.26% | +500,000 | New |
| EcoR1 Capital, LLC | 600,000 | $11.1M | 0.34% | +600,000 | New |
| Cormorant Asset Management, LP | 734,350 | $13.6M | 0.92% | +734,350 | New |
| Casdin Capital, LLC | 734,350 | $13.6M | 1.07% | +734,350 | New |
| Vanguard Group Inc | 872,523 | $16.2M | 0.00% | +872,523 | New |
| Deerfield Management Company, L.P. (Series C) | 885,314 | $16.4M | 0.34% | +885,314 | New |
| Baker Bros. Advisors LP | 1,028,466 | $19.1M | 0.11% | +1,028,466 | New |
| BlackRock Inc. | 1,487,846 | $27.6M | 0.00% | +1,487,846 | New |
| ARK Investment Management LLCSuperinvestorARK Invest | 1,639,984 | $30.5M | 0.26% | +1,639,984 | New |
| FIL Ltd | 1,805,558 | $33.5M | 0.04% | +1,805,558 | New |
| MWG Management Limited | 1,835,876 | $34.1M | 17.42% | +1,835,876 | New |
| Redmile Group, LLC | 2,209,350 | $41.0M | 1.68% | +2,209,350 | New |
| Price T Rowe Associates Inc | 2,378,582 | $44.2M | 0.01% | +2,378,582 | New |
| FMR LLC | 8,463,046 | $157.2M | 0.02% | +8,463,046 | New |
| Alphabet Inc. | 13,284,688 | $246.8M | 14.34% | +13,284,688 | New |