Prelude Therapeutics Inc
PRLD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001678660
No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Prelude Therapeutics Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 55
- +8 vs. Q4 2025
- Shares held
- 30.8M
- +3.71M (+13.7%) vs. Q4 2025
- Total value
- $105.2M
- +$26.8M (+34.1%) vs. Q4 2025
- New holders
- 13
- 20 more added
- Sold out
- 5
- 11 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $264.3M |
| Q1 2026 | 55 | $105.2M |
| Q4 2025 | 48 | $82.6M |
| Q3 2025 | 47 | $39.1M |
| Q2 2025 | 50 | $22.0M |
| Q1 2025 | 59 | $23.3M |
| Q4 2024 | 62 | $41.0M |
| Q3 2024 | 70 | $74.0M |
| Q2 2024 | 61 | $129.2M |
| Q1 2024 | 58 | $162.1M |
| Q4 2023 | 56 | $148.3M |
| Q3 2023 | 60 | $113.1M |
| Q2 2023 | 55 | $176.2M |
| Q1 2023 | 55 | $179.6M |
| Q4 2022 | 60 | $188.3M |
| Q3 2022 | 53 | $210.3M |
| Q2 2022 | 62 | $170.9M |
| Q1 2022 | 68 | $235.4M |
| Q4 2021 | 75 | $437.6M |
| Q3 2021 | 61 | $1.12B |
| Q2 2021 | 57 | $986.6M |
| Q1 2021 | 60 | $1.41B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Citigroup Inc | 5 | $17 | 0.00% | +4+400.0% | Added |
| Optiver Holding B.V. | 20 | $68 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 62 | $190 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 95 | $325 | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 230 | $787 | 0.00% | +230 | New |
| CWM, LLC | 573 | $1.96K | 0.00% | −119−17.2% | Reduced |
| Caldwell Sutter Capital, Inc. | 1,000 | $3.42K | 0.00% | −1,000−50.0% | Reduced |
| The PNC Financial Services Group, Inc. | 1,171 | $4.00K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 1,634 | $5.59K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 2,331 | $8.00K | 0.00% | +589+33.8% | Added |
| SBI Securities Co., Ltd. | 2,641 | $9.03K | 0.00% | −100−3.6% | Reduced |
| Group One Trading, L.P. | 3,907 | $13.4K | 0.00% | +3,407+681.4% | Added |
| Vanguard Global Advisers, LLC | 4,636 | $15.9K | 0.00% | +4,636 | New |
| FMR LLC | 6,009 | $20.6K | 0.00% | −143−2.3% | Reduced |
| Barclays PLC | 8,600 | $29.4K | 0.00% | −20.0% | Reduced |
| American Century Companies Inc | 10,294 | $35.2K | 0.00% | +10,294 | New |
| Graham Capital Management, L.P. | 11,343 | $38.8K | 0.00% | +11,343 | New |
| Nine Masts Capital Ltd | 11,699 | $40.0K | 0.01% | +11,699 | New |
| Diametric Capital, LP | 11,980 | $41.0K | 0.01% | +11,980 | New |
| HSBC Holdings PLC | 13,652 | $47.9K | 0.00% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 16,329 | $55.8K | 0.00% | −42,839−72.4% | Reduced |
| Qube Research & Technologies Ltd | 16,417 | $56.1K | 0.00% | −5,134−23.8% | Reduced |
| Prudential Financial Inc | 17,420 | $59.6K | 0.00% | +1,900+12.2% | Added |
| Omers Administration Corp | 32,700 | $111.8K | 0.00% | −40,300−55.2% | Reduced |
| Cerity Partners LLC | 32,875 | $112.4K | 0.00% | −78−0.2% | Reduced |
| Dimensional Fund Advisors LP | 35,210 | $119.7K | 0.00% | +35,210 | New |
| Colony Group, LLC | 50,007 | $171.0K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 50,120 | $171.4K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 53,500 | $183.0K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 56,525 | $193.3K | 0.00% | +46,717+476.3% | Added |
| XTX Topco Ltd | 57,190 | $195.6K | 0.00% | +7,031+14.0% | Added |
| HRT Financial LP | 58,699 | $200.0K | 0.00% | +58,699 | New |
| UBS Group AG | 64,505 | $220.6K | 0.00% | +62,648+3,373.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 109,085 | $373.1K | 0.00% | +62,995+136.7% | Added |
| Citadel Advisors LLC | 124,378 | $425.4K | 0.00% | +124,378 | New |
| State Street Corp | 138,231 | $472.8K | 0.00% | +10,939+8.6% | Added |
| ADAR1 Capital Management, LLC | 152,825 | $522.7K | 0.03% | +152,825 | New |
| Vanguard Fiduciary Trust Co | 157,380 | $538.2K | 0.00% | +157,380 | New |
| Jane Street Group, LLC | 192,963 | $659.9K | 0.00% | +81,923+73.8% | Added |
| Goldman Sachs Group Inc | 236,469 | $808.7K | 0.00% | +118,992+101.3% | Added |
| Susquehanna International Group, LLP | 267,788 | $915.8K | 0.00% | +131,879+97.0% | Added |
| Renaissance Technologies LLC | 275,200 | $941.2K | 0.00% | +3,900+1.4% | Added |
| Geode Capital Management, LLC | 302,458 | $1.03M | 0.00% | +29,572+10.8% | Added |
| BlackRock, Inc. | 321,886 | $1.10M | 0.00% | +55,606+20.9% | Added |
| Morgan Stanley | 322,161 | $1.10M | 0.00% | −12,755−3.8% | Reduced |
| Marshall Wace, LLP | 358,906 | $1.23M | 0.00% | +85,023+31.0% | Added |
| Millennium Management LLC | 382,737 | $1.31M | 0.00% | +231,740+153.5% | Added |
| Acadian Asset Management LLC | 511,519 | $1.75M | 0.00% | −24,184−4.5% | Reduced |
| Sphera Funds Management Ltd. | 558,339 | $1.91M | 0.33% | +435,587+354.9% | Added |
| Two Sigma Investments, LP | 923,626 | $3.16M | 0.00% | +134,931+17.1% | Added |
| EcoR1 Capital, LLC | 947,049 | $3.24M | 0.14% | +947,049 | New |
| Vanguard Capital Management LLC | 1,230,406 | $4.21M | 0.00% | +1,230,406 | New |
| Kynam Capital Management, LP | 1,592,551 | $5.45M | 0.35% | +803,684+101.9% | Added |
| Baker Bros. Advisors LP | 10,123,824 | $34.6M | 0.20% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 10,909,256 | $37.3M | 0.85% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −755,956−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −237,300−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −160,652−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −70,546−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |