Prelude Therapeutics Inc
PRLD- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001678660
No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Prelude Therapeutics Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 47
- −3 vs. Q2 2025
- Shares held
- 27.2M
- −26.0K (−0.1%) vs. Q2 2025
- Total value
- $39.1M
- +$17.1M (+77.8%) vs. Q2 2025
- New holders
- 5
- 8 more added
- Sold out
- 8
- 23 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 75 | $264.3M |
| Q1 2026 | 55 | $105.2M |
| Q4 2025 | 48 | $82.6M |
| Q3 2025 | 47 | $39.1M |
| Q2 2025 | 50 | $22.0M |
| Q1 2025 | 59 | $23.3M |
| Q4 2024 | 62 | $41.0M |
| Q3 2024 | 70 | $74.0M |
| Q2 2024 | 61 | $129.2M |
| Q1 2024 | 58 | $162.1M |
| Q4 2023 | 56 | $148.3M |
| Q3 2023 | 60 | $113.1M |
| Q2 2023 | 55 | $176.2M |
| Q1 2023 | 55 | $179.6M |
| Q4 2022 | 60 | $188.3M |
| Q3 2022 | 53 | $210.3M |
| Q2 2022 | 62 | $170.9M |
| Q1 2022 | 68 | $235.4M |
| Q4 2021 | 75 | $437.6M |
| Q3 2021 | 61 | $1.12B |
| Q2 2021 | 57 | $986.6M |
| Q1 2021 | 60 | $1.41B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Simplex Trading, LLC | 153 | $0 | 0.00% | +153 | New |
| SRS Capital Advisors, Inc. | 15 | $22 | 0.00% | +15 | New |
| Essential Partners LLC | 17 | $24 | 0.00% | −70−80.5% | Reduced |
| IFP Advisors, Inc | 18 | $26 | 0.00% | −16−47.1% | Reduced |
| Optiver Holding B.V. | 20 | $29 | 0.00% | +20 | New |
| BNP Paribas Arbitrage, SA | 52 | $75 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 89 | $128 | 0.00% | −59−39.9% | Reduced |
| Group One Trading, L.P. | 500 | $720 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 1,171 | $1.69K | 0.00% | −9−0.8% | Reduced |
| CWM, LLC | 1,219 | $2.00K | 0.00% | −2,795−69.6% | Reduced |
| Nisa Investment Advisors, LLC | 1,634 | $2.35K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 2,741 | $3.95K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 3,879 | $5.58K | 0.00% | +1,930+99.0% | Added |
| UBS Group AG | 4,171 | $6.01K | 0.00% | −100,033−96.0% | Reduced |
| Citigroup Inc | 5,975 | $8.60K | 0.00% | +1,257+26.6% | Added |
| Tower Research Capital LLC (TRC) | 6,927 | $9.97K | 0.00% | −9,872−58.8% | Reduced |
| Royal Bank of Canada | 7,712 | $11.0K | 0.00% | +4,885+172.8% | Added |
| Barclays PLC | 8,712 | $12.5K | 0.00% | +110+1.3% | Added |
| Bank of America Corp | 8,848 | $12.7K | 0.00% | −2,445−21.7% | Reduced |
| FMR LLC | 9,099 | $13.1K | 0.00% | −2,068−18.5% | Reduced |
| AQR Capital Management LLC | 10,500 | $15.1K | 0.00% | −33,147−75.9% | Reduced |
| HSBC Holdings PLC | 13,747 | $20.2K | 0.00% | −3,664−21.0% | Reduced |
| XTX Topco Ltd | 15,578 | $22.4K | 0.00% | −26,995−63.4% | Reduced |
| HRT Financial LP | 16,901 | $24.0K | 0.00% | +16,901 | New |
| Prudential Financial Inc | 25,840 | $37.2K | 0.00% | +25,840 | New |
| Cerity Partners LLC | 34,333 | $49.4K | 0.00% | −2,060−5.7% | Reduced |
| Jane Street Group, LLC | 34,822 | $50.1K | 0.00% | −56,931−62.0% | Reduced |
| Northern Trust Corp | 36,421 | $52.4K | 0.00% | −1,706−4.5% | Reduced |
| Bridgeway Capital Management, LLC | 53,500 | $77.0K | 0.00% | −35,000−39.5% | Reduced |
| Manufacturers Life Insurance Company, The | 69,252 | $99.7K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 75,161 | $108.0K | 0.01% | +3,783+5.3% | Added |
| Goldman Sachs Group Inc | 79,327 | $114.2K | 0.00% | −69,851−46.8% | Reduced |
| State Street Corp | 97,592 | $140.5K | 0.00% | 00.0% | Unchanged |
| Shay Capital LLC | 100,000 | $144.0K | 0.03% | +25,000+33.3% | Added |
| Two Sigma Investments, LP | 152,233 | $219.2K | 0.00% | −2,744−1.8% | Reduced |
| TD Asset Management Inc | 160,652 | $231.3K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 217,568 | $313.4K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 222,700 | $320.7K | 0.00% | −2,300−1.0% | Reduced |
| BlackRock, Inc. | 264,973 | $381.6K | 0.00% | −167,586−38.7% | Reduced |
| Morgan Stanley | 284,203 | $409.3K | 0.00% | −179−0.1% | Reduced |
| Acadian Asset Management LLC | 540,565 | $777.0K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 544,000 | $783.4K | 0.00% | −37,800−6.5% | Reduced |
| Price T Rowe Associates Inc | 876,338 | $1.26M | 0.00% | −51,270−5.5% | Reduced |
| Vanguard Group Inc | 992,854 | $1.43M | 0.00% | +60,284+6.5% | Added |
| Millennium Management LLC | 1,147,044 | $1.65M | 0.00% | +898,621+361.7% | Added |
| Baker Bros. Advisors LP | 10,123,824 | $14.6M | 0.11% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 10,909,256 | $15.7M | 0.38% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 0 | $0 | 0.00% | −211,859−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −80,845−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −47,788−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −41,747−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −39,977−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −33,625−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −297−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −13−100.0% | Sold out |