Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 422
- +57 vs. Q1 2026
- Shares held
- 30.3M
- +2.19M (+7.8%) vs. Q1 2026
- Total value
- $11.1B
- +$3.82B (+52.7%) vs. Q1 2026
- New holders
- 93
- 178 more added
- Sold out
- 36
- 109 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jupiter Topco LLC | 256,665 | $95.4M | 0.04% | +256,665 | New |
| Norges Bank | 259,030 | $96.3M | 0.01% | +259,030 | New |
| Franklin Resources Inc | 261,917 | $97.3M | 0.02% | +82,652+46.1% | Added |
| Northern Trust Corp | 283,784 | $105.5M | 0.01% | +31,321+12.4% | Added |
| Goldman Sachs Group Inc | 298,841 | $111.1M | 0.01% | +83,892+39.0% | Added |
| Invesco Ltd. | 324,755 | $120.7M | 0.01% | +73,382+29.2% | Added |
| First Trust Advisors LP | 324,900 | $120.8M | 0.07% | −25,621−7.3% | Reduced |
| Dimensional Fund Advisors LP | 476,038 | $176.9M | 0.03% | +7,048+1.5% | Added |
| Frazier Life Sciences Management, L.P. | 481,307 | $178.9M | 3.90% | 00.0% | Unchanged |
| William Blair Investment Management, LLC | 570,153 | $211.9M | 0.64% | +162,975+40.0% | Added |
| Redmile Group, LLC | 632,005 | $234.9M | 15.77% | −41,500−6.2% | Reduced |
| Hood River Capital Management LLC | 663,375 | $246.6M | 1.79% | +43,789+7.1% | Added |
| Price T Rowe Associates Inc | 687,400 | $255.5M | 0.03% | +202,326+41.7% | Added |
| Geode Capital Management, LLC | 698,993 | $259.8M | 0.01% | +55,018+8.5% | Added |
| Capital World Investors | 777,843 | $289.1M | 0.03% | −46,877−5.7% | Reduced |
| Soleus Capital Management, L.P. | 939,254 | $349.1M | 12.03% | −213,833−18.5% | Reduced |
| Vanguard Capital Management LLC | 1,240,567 | $461.1M | 0.01% | +75,243+6.5% | Added |
| State Street Corp | 1,351,158 | $502.2M | 0.01% | +36,724+2.8% | Added |
| Vanguard Portfolio Management LLC | 1,574,905 | $585.3M | 0.03% | +118,178+8.1% | Added |
| Avoro Capital Advisors LLC | 2,888,888 | $1.07B | 9.64% | 00.0% | Unchanged |
| BlackRock, Inc. | 4,181,432 | $1.55B | 0.02% | +240,976+6.1% | Added |
| FMR LLC | 4,418,197 | $1.64B | 0.07% | +44,210+1.0% | Added |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −68,343−100.0% | Sold out |
| Zacks Investment Management | 0 | $0 | 0.00% | −17,919−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −17,795−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −14,476−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −8,257−100.0% | Sold out |
| Decheng Capital LLC | 0 | $0 | 0.00% | −7,300−100.0% | Sold out |
| FORA Capital, LLC | 0 | $0 | 0.00% | −5,732−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −4,664−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −4,119−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −3,189−100.0% | Sold out |
| Blackstone Group Inc. | 0 | $0 | 0.00% | −2,246−100.0% | Sold out |
| Entropy Technologies, LP | 0 | $0 | 0.00% | −2,200−100.0% | Sold out |
| Natixis | 0 | $0 | 0.00% | −1,736−100.0% | Sold out |
| Cynosure Management, LLC | 0 | $0 | 0.00% | −1,649−100.0% | Sold out |
| IMC-Chicago, LLC | 0 | $0 | 0.00% | −1,591−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −1,300−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −1,138−100.0% | Sold out |
| GTS Securities LLC | 0 | $0 | 0.00% | −1,108−100.0% | Sold out |
| Farallon Capital Management, L.L.C. | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −996−100.0% | Sold out |
| Private Advisor Group, LLC | 0 | $0 | 0.00% | −947−100.0% | Sold out |
| Coldstream Capital Management Inc | 0 | $0 | 0.00% | −939−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −857−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −236−100.0% | Sold out |
| Cullen/Frost Bankers, Inc. | 0 | $0 | 0.00% | −187−100.0% | Sold out |
| Sound Income Strategies, LLC | 0 | $0 | 0.00% | −137−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −105−100.0% | Sold out |
| Steward Partners Investment Advisory, LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Dauntless Investment Group, LLC | 0 | $0 | 0.00% | −73−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Root Financial Partners, LLC | 0 | $0 | 0.00% | −17−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −13−100.0% | Sold out |
| Rachor Investment Advisory Services, LLC | 0 | $0 | 0.00% | −8−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| Vermillion Wealth Management, Inc. | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Ameritas Advisory Services, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Janus Henderson Group PLC | – | – | – | – | Not filed |
| CWM, LLC | – | – | – | – | Not filed |
| USA Financial Portformulas Corp | – | – | – | – | Not filed |