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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
422
+57 vs. Q1 2026
Shares held
30.3M
+2.19M (+7.8%) vs. Q1 2026
Total value
$11.1B
+$3.82B (+52.7%) vs. Q1 2026
New holders
93
178 more added
Sold out
36
109 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 422 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2026: $11.1B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2026.

Institutions holding KRYS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Commonwealth Equity Services, LLC12,116$4.50M0.01%+525+4.5%Added
Torray LLC12,156$4.52M0.61%+124+1.0%Added
Nomura Asset Management International Inc.12,642$4.70M0.01%+2,424+23.7%Added
Allianz Asset Management GmbH12,731$4.73M0.00%+10,831+570.1%Added
Credit Agricole S A12,976$4.82M0.01%00.0%Unchanged
State of Wisconsin Investment Board12,998$4.83M0.01%−7,693−37.2%Reduced
Kornitzer Capital Management Inc13,126$4.88M0.10%+13,126New
Envestnet Asset Management Inc13,212$4.91M0.00%+1,229+10.3%Added
State of Alaska, Department of Revenue13,385$4.97M0.05%−4,099−23.4%Reduced
Illinois Municipal Retirement Fund13,455$5.00M0.06%−696−4.9%Reduced
Natixis Advisors, L.P.13,649$5.07M0.01%+1,524+12.6%Added
AQR Capital Management LLC14,002$5.20M0.00%−112−0.8%Reduced
Fiera Capital Corp14,251$5.30M0.02%−9,895−41.0%Reduced
State Board of Administration of Florida Retirement System14,483$5.38M0.01%−1,273−8.1%Reduced
MetLife Investment Management15,196$5.65M0.03%+1,654+12.2%Added
EFG International AG15,304$5.69M0.10%−4,745−23.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.15,297$5.69M0.01%+176+1.2%Added
Cim, LLC15,703$5.84M0.75%+713+4.8%Added
WCM Investment Management, LLC15,753$5.96M0.01%+15,753New
SG Americas Securities, LLC16,147$6.00M0.00%+10,248+173.7%Added
Castleark Management LLC16,150$6.00M0.16%−15,480−48.9%Reduced
Mediolanum International Funds Ltd15,940$6.03M0.05%+15,940New
EAM Investors, LLC16,227$6.03M0.54%−256−1.6%Reduced
Rhenman & Partners Asset Management AB16,325$6.07M0.57%−350−2.1%Reduced
Cinctive Capital Management LP16,367$6.08M0.24%+13,493+469.5%Added
ADAR1 Capital Management, LLC16,420$6.10M0.29%−3,594−18.0%Reduced
New York State Teachers Retirement System16,801$6.24M0.01%+1,164+7.4%Added
Van Eck Associates Corp17,071$6.34M0.00%+17,071New
Thrivent Financial for Lutherans17,229$6.40M0.01%+30.0%Added
GW&K Investment Management, LLC18,295$6.80M0.05%−950−4.9%Reduced
Lisanti Capital Growth, LLC19,050$7.08M1.56%+535+2.9%Added
Polygon Management Ltd.19,668$7.31M1.19%00.0%Unchanged
Pinnacle Financial Partners, Inc.20,243$7.52M0.05%+63+0.3%Added
Bessemer Group Inc20,285$7.54M0.01%00.0%Unchanged
Creative Planning20,318$7.55M0.00%+4,381+27.5%Added
Vanguard Asset Management, Ltd21,390$7.95M0.01%+784+3.8%Added
Great West Life Assurance Co21,711$8.06M0.01%+298+1.4%Added
Elmind Capital, LP22,000$8.18M2.05%00.0%Unchanged
TD Asset Management Inc22,712$8.44M0.01%−20,606−47.6%Reduced
Alliancebernstein L.P.34,039$8.79M0.00%+2,110+6.6%Added
California State Teachers Retirement System23,692$8.81M0.01%−2,494−9.5%Reduced
HealthInvest Partners AB24,019$8.93M2.40%−13,560−36.1%Reduced
Standard Life Aberdeen plc25,141$9.34M0.01%−5,014−16.6%Reduced
Manufacturers Life Insurance Company, The25,867$9.61M0.01%−10,202−28.3%Reduced
Fisher Asset Management, LLC27,676$10.3M0.00%−108−0.4%Reduced
CI Private Wealth, LLC30,558$11.4M0.02%+27,035+767.4%Added
Deutsche Bank AG31,836$11.8M0.00%+7,005+28.2%Added
Mutual of America Capital Management LLC31,998$11.9M0.12%−3,861−10.8%Reduced
Prudential Financial Inc32,662$12.1M0.01%+3,024+10.2%Added
Granite Investment Partners, LLC32,837$12.2M0.63%+8,553+35.2%Added
New York State Common Retirement Fund34,033$12.6M0.02%+2,691+8.6%Added
Wells Fargo & Company34,502$12.8M0.00%+19,514+130.2%Added
Life Cycle Investment Partners Ltd35,124$13.1M0.06%+35,124New
Wellington Management Group LLP36,936$13.7M0.00%+26,709+261.2%Added
SEB Asset Management AB37,731$14.0M0.05%−8,612−18.6%Reduced
UBS Asset Management Americas Inc38,697$14.4M0.00%+1,760+4.8%Added
Congress Asset Management Co40,134$14.9M0.09%+40,134New
Gilder Gagnon Howe & Co LLC40,296$15.0M0.15%+168+0.4%Added
Swiss National Bank41,360$15.4M0.01%−1,640−3.8%Reduced
Federated Hermes, Inc.43,848$16.3M0.02%+8,353+23.5%Added
Victory Capital Management Inc44,935$16.7M0.01%+4,220+10.4%Added
ACT Capital Management, LLC45,000$16.7M10.93%−15,477−25.6%Reduced
Palisades Investment Partners, LLC47,801$17.8M5.05%+2,396+5.3%Added
Ameriprise Financial Inc48,790$18.1M0.00%−1,047−2.1%Reduced
Neuberger Berman Group LLC51,876$19.3M0.01%+18,792+56.8%Added
Allspring Global Investments Holdings, LLC52,407$19.5M0.03%+49,932+2,017.5%Added
Russell Investments Group, Ltd.52,621$19.6M0.02%+26,411+100.8%Added
SEI Investments Co54,040$20.1M0.02%+7,470+16.0%Added
Bridgewater Associates, LP54,489$20.3M0.08%+8,122+17.5%Added
Citigroup Inc56,016$20.8M0.01%+24,844+79.7%Added
C WorldWide Group Holding A/S57,809$21.5M0.52%−10,000−14.7%Reduced
Legal & General Group Plc58,580$21.8M0.00%−470−0.8%Reduced
Renaissance Technologies LLC59,680$22.2M0.03%+50,080+521.7%Added
Rhumbline Advisers61,236$22.8M0.02%−6,863−10.1%Reduced
Segall Bryant & Hamill, LLC65,211$24.2M0.29%−14,286−18.0%Reduced
Biondo Investment Advisors, LLC70,945$26.4M3.23%−1,100−1.5%Reduced
Bellevue Group AG77,530$28.8M0.61%−404,255−83.9%Reduced
S Squared Technology, LLC77,545$28.8M8.94%−8,670−10.1%Reduced
OrbiMed Advisors LLC83,200$30.9M0.59%+14,100+20.4%Added
JPMorgan Chase & Co87,342$33.5M0.00%−11,763−11.9%Reduced
Handelsbanken Fonder AB90,407$33.6M0.10%−993−1.1%Reduced
BNP Paribas Arbitrage, SA92,234$34.3M0.02%−797−0.9%Reduced
Westfield Capital Management Co LP98,707$36.7M0.12%+98,707New
1832 Asset Management L.P.99,300$36.9M0.05%+56,700+133.1%Added
Public Sector Pension Investment Board105,515$39.2M0.10%+13,229+14.3%Added
Pictet Asset Management Holding SA107,798$40.1M0.04%−2,867−2.6%Reduced
TimesSquare Capital Management, LLC111,545$41.5M0.61%−797−0.7%Reduced
Voya Investment Management LLC124,442$46.3M0.04%+16,045+14.8%Added
Braidwell LP128,975$47.9M1.77%−53,450−29.3%Reduced
Nuveen, LLC146,520$54.5M0.01%+3,152+2.2%Added
UBS Group AG148,316$55.1M0.01%+4,791+3.3%Added
Woodline Partners LP150,616$56.0M0.17%00.0%Unchanged
Raymond James Financial Inc158,675$59.0M0.02%+2,611+1.7%Added
Bank of New York Mellon Corp163,610$60.8M0.01%+14,303+9.6%Added
Principal Financial Group Inc169,550$63.0M0.03%+7,480+4.6%Added
Vanguard Fiduciary Trust Co189,528$70.4M0.02%+10,367+5.8%Added
Vestor Capital, LLC700,914$78.2M6.62%+700,714+350,357.0%Added
Morgan Stanley235,491$87.5M0.00%+26,409+12.6%Added
Charles Schwab Investment Management Inc254,828$94.7M0.01%+12,842+5.3%Added
Bank of America Corp256,431$95.3M0.01%−4,216−1.6%Reduced