Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 368
- +41 vs. Q4 2025
- Shares held
- 28.4M
- +3.02M (+11.9%) vs. Q4 2025
- Total value
- $7.32B
- +$1.08B (+17.2%) vs. Q4 2025
- New holders
- 76
- 138 more added
- Sold out
- 35
- 105 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Alliancebernstein L.P. | 31,929 | $7.87M | 0.00% | +400+1.3% | Added |
| Citigroup Inc | 31,172 | $8.05M | 0.01% | +1,229+4.1% | Added |
| New York State Common Retirement Fund | 31,342 | $8.10M | 0.01% | 00.0% | Unchanged |
| Castleark Management LLC | 31,630 | $8.17M | 0.27% | +2,370+8.1% | Added |
| Neuberger Berman Group LLC | 33,084 | $8.55M | 0.01% | +32,051+3,102.7% | Added |
| Federated Hermes, Inc. | 35,495 | $9.17M | 0.01% | +954+2.8% | Added |
| Mutual of America Capital Management LLC | 35,859 | $9.26M | 0.11% | −1,410−3.8% | Reduced |
| Manufacturers Life Insurance Company, The | 36,069 | $9.32M | 0.01% | −4,560−11.2% | Reduced |
| UBS Asset Management Americas Inc | 36,937 | $9.54M | 0.00% | +3,320+9.9% | Added |
| Gilder Gagnon Howe & Co LLC | 40,128 | $10.4M | 0.12% | +40,128 | New |
| Victory Capital Management Inc | 40,715 | $10.5M | 0.01% | +14,254+53.9% | Added |
| 1832 Asset Management L.P. | 42,600 | $11.0M | 0.01% | +25,000+142.0% | Added |
| Swiss National Bank | 43,000 | $11.1M | 0.01% | +100+0.2% | Added |
| TD Asset Management Inc | 43,318 | $11.2M | 0.01% | −10,824−20.0% | Reduced |
| Palisades Investment Partners, LLC | 45,405 | $11.7M | 4.60% | +2,640+6.2% | Added |
| SEB Asset Management AB | 46,343 | $12.0M | 0.05% | +46,343 | New |
| Bridgewater Associates, LP | 46,367 | $12.0M | 0.05% | +36,352+363.0% | Added |
| SEI Investments Co | 46,570 | $12.0M | 0.01% | +14,260+44.1% | Added |
| Ameriprise Financial Inc | 49,837 | $12.9M | 0.00% | −2,508−4.8% | Reduced |
| Legal & General Group Plc | 59,050 | $15.3M | 0.00% | −4,311−6.8% | Reduced |
| ACT Capital Management, LLC | 60,477 | $15.6M | 12.28% | −230.0% | Reduced |
| C WorldWide Group Holding A/S | 67,809 | $17.5M | 0.38% | −18,000−21.0% | Reduced |
| Rhumbline Advisers | 68,099 | $17.6M | 0.02% | +1,663+2.5% | Added |
| Marshall Wace, LLP | 68,343 | $17.7M | 0.02% | −115,411−62.8% | Reduced |
| OrbiMed Advisors LLC | 69,100 | $17.8M | 0.41% | −50,700−42.3% | Reduced |
| Biondo Investment Advisors, LLC | 72,045 | $18.6M | 2.39% | +3,915+5.7% | Added |
| Segall Bryant & Hamill, LLC | 79,497 | $20.5M | 0.29% | −3,749−4.5% | Reduced |
| S Squared Technology, LLC | 86,215 | $22.3M | 8.43% | −10,000−10.4% | Reduced |
| Handelsbanken Fonder AB | 91,400 | $23.6M | 0.08% | −14,400−13.6% | Reduced |
| Public Sector Pension Investment Board | 92,286 | $23.8M | 0.07% | +2,924+3.3% | Added |
| BNP Paribas Arbitrage, SA | 93,031 | $24.0M | 0.02% | +39,120+72.6% | Added |
| JPMorgan Chase & Co | 99,105 | $24.5M | 0.00% | −35,519−26.4% | Reduced |
| Voya Investment Management LLC | 108,397 | $28.0M | 0.03% | +5,136+5.0% | Added |
| Pictet Asset Management Holding SA | 110,665 | $28.6M | 0.03% | −45,903−29.3% | Reduced |
| TimesSquare Capital Management, LLC | 112,342 | $29.0M | 0.49% | +14,942+15.3% | Added |
| Nuveen, LLC | 143,368 | $37.0M | 0.01% | −45,726−24.2% | Reduced |
| UBS Group AG | 143,525 | $37.1M | 0.01% | −16,070−10.1% | Reduced |
| Bank of New York Mellon Corp | 149,307 | $38.6M | 0.01% | −2,006−1.3% | Reduced |
| Woodline Partners LP | 150,616 | $38.9M | 0.15% | 00.0% | Unchanged |
| Raymond James Financial Inc | 156,064 | $39.5M | 0.01% | +79,526+103.9% | Added |
| Principal Financial Group Inc | 162,070 | $41.9M | 0.02% | −3,004−1.8% | Reduced |
| Vanguard Fiduciary Trust Co | 179,161 | $46.3M | 0.01% | +179,161 | New |
| Franklin Resources Inc | 179,265 | $46.3M | 0.01% | +53,590+42.6% | Added |
| Braidwell LP | 182,425 | $47.1M | 1.57% | −19,676−9.7% | Reduced |
| Morgan Stanley | 209,082 | $54.0M | 0.00% | −12,399−5.6% | Reduced |
| Goldman Sachs Group Inc | 214,949 | $55.5M | 0.01% | −78,576−26.8% | Reduced |
| Charles Schwab Investment Management Inc | 241,986 | $62.5M | 0.01% | −788−0.3% | Reduced |
| Invesco Ltd. | 251,373 | $64.9M | 0.01% | +191,365+318.9% | Added |
| Northern Trust Corp | 252,463 | $65.2M | 0.01% | +5,020+2.0% | Added |
| Bank of America Corp | 260,647 | $67.3M | 0.00% | +69,840+36.6% | Added |
| Janus Henderson Group PLC | 266,659 | $68.9M | 0.03% | +47,219+21.5% | Added |
| First Trust Advisors LP | 350,521 | $90.5M | 0.06% | +105,245+42.9% | Added |
| William Blair Investment Management, LLC | 407,178 | $105.2M | 0.35% | +30,838+8.2% | Added |
| Dimensional Fund Advisors LP | 468,990 | $121.1M | 0.03% | −23,978−4.9% | Reduced |
| Frazier Life Sciences Management, L.P. | 481,307 | $124.3M | 3.20% | −7,153−1.5% | Reduced |
| Bellevue Group AG | 481,785 | $124.5M | 2.96% | +71,462+17.4% | Added |
| Price T Rowe Associates Inc | 485,074 | $125.3M | 0.01% | −44,881−8.5% | Reduced |
| Hood River Capital Management LLC | 619,586 | $160.1M | 1.61% | +6,284+1.0% | Added |
| Geode Capital Management, LLC | 643,975 | $166.4M | 0.01% | +32,097+5.2% | Added |
| Redmile Group, LLC | 673,505 | $174.0M | 11.52% | −4,200−0.6% | Reduced |
| Capital World Investors | 824,720 | $213.0M | 0.03% | +15,220+1.9% | Added |
| Soleus Capital Management, L.P. | 1,153,087 | $297.9M | 12.06% | +212,028+22.5% | Added |
| Vanguard Capital Management LLC | 1,165,324 | $301.0M | 0.01% | +1,165,324 | New |
| State Street Corp | 1,314,434 | $339.5M | 0.01% | −27,869−2.1% | Reduced |
| Vanguard Portfolio Management LLC | 1,456,727 | $376.3M | 0.02% | +1,456,727 | New |
| Avoro Capital Advisors LLC | 2,888,888 | $746.3M | 7.35% | 00.0% | Unchanged |
| BlackRock, Inc. | 3,940,456 | $1.02B | 0.02% | +2,639+0.1% | Added |
| FMR LLC | 4,373,987 | $1.13B | 0.06% | +24,359+0.6% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 0 | $0 | 0.00% | −46,732−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −17,500−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −16,969−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −14,814−100.0% | Sold out |
| DekaBank Deutsche Girozentrale | 0 | $0 | 0.00% | −15,503−100.0% | Sold out |
| Main Management ETF Advisors, LLC | 0 | $0 | 0.00% | −10,179−100.0% | Sold out |
| Perigon Wealth Management, LLC | 0 | $0 | 0.00% | −8,970−100.0% | Sold out |
| NFJ Investment Group, LLC | 0 | $0 | 0.00% | −8,249−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −5,874−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −3,527−100.0% | Sold out |
| Baader Bank INC | 0 | $0 | 0.00% | −3,163−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −2,902−100.0% | Sold out |
| EP Wealth Advisors, LLC | 0 | $0 | 0.00% | −1,846−100.0% | Sold out |
| City Center Advisors, LLC | 0 | $0 | 0.00% | −1,628−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −1,554−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −1,535−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −1,361−100.0% | Sold out |
| Roman Butler Fullerton & Co | 0 | $0 | 0.00% | −1,125−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −1,058−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −1,032−100.0% | Sold out |
| Avanza Fonder AB | 0 | $0 | 0.00% | −996−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −856−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −600−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −565−100.0% | Sold out |
| Danske Bank A/S | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Greenline Wealth Management LLC | 0 | $0 | 0.00% | −136−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −86−100.0% | Sold out |
| SageView Advisory Group, LLC | 0 | $0 | 0.00% | −57−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −28−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −27−100.0% | Sold out |
| Accent Capital Management, LLC | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Flagship Harbor Advisors, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |