Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 368
- +41 vs. Q4 2025
- Shares held
- 28.4M
- +3.02M (+11.9%) vs. Q4 2025
- Total value
- $7.32B
- +$1.08B (+17.2%) vs. Q4 2025
- New holders
- 76
- 138 more added
- Sold out
- 35
- 105 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Guggenheim Capital LLC | 3,518 | $908.8K | 0.01% | −3,734−51.5% | Reduced |
| Maryland State Retirement & Pension System | 3,764 | $972.3K | 0.02% | −10−0.3% | Reduced |
| Regal Investment Advisors LLC | 4,050 | $1.05M | 0.06% | −310−7.1% | Reduced |
| Omers Administration Corp | 4,100 | $1.06M | 0.01% | +4,100 | New |
| Susquehanna Portfolio Strategies, LLC | 4,104 | $1.06M | 0.02% | 00.0% | Unchanged |
| Millennium Management LLC | 4,119 | $1.06M | 0.00% | −10,539−71.9% | Reduced |
| Seven Fleet Capital Management LP | 4,316 | $1.11M | 0.35% | +316+7.9% | Added |
| Allstate Corp | 4,433 | $1.15M | 0.01% | +4,433 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 4,664 | $1.20M | 0.00% | +4,664 | New |
| Cookson Peirce & Co Inc | 4,694 | $1.21M | 0.05% | −1,260−21.2% | Reduced |
| KLP Kapitalforvaltning AS | 4,800 | $1.24M | 0.00% | +100+2.1% | Added |
| Odyssean, LLC | 4,819 | $1.24M | 0.45% | +1,805+59.9% | Added |
| Kennedy Capital Management, Inc. | 4,904 | $1.27M | 0.03% | +403+9.0% | Added |
| Barclays PLC | 4,969 | $1.28M | 0.00% | −55,093−91.7% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 5,139 | $1.33M | 0.00% | +1,275+33.0% | Added |
| ProShare Advisors LLC | 5,177 | $1.34M | 0.00% | −939−15.4% | Reduced |
| China Universal Asset Management Co., Ltd. | 5,187 | $1.34M | 0.10% | +462+9.8% | Added |
| Vanguard Investments Australia, Ltd. | 5,330 | $1.38M | 0.00% | +5,330 | New |
| Amundi | 5,706 | $1.47M | 0.00% | +1,952+52.0% | Added |
| FORA Capital, LLC | 5,732 | $1.48M | 0.11% | +3,620+171.4% | Added |
| SG Americas Securities, LLC | 5,899 | $1.52M | 0.00% | −13,010−68.8% | Reduced |
| Fifth Third Bancorp | 5,925 | $1.53M | 0.00% | +5,779+3,958.2% | Added |
| Oregon Public Employees Retirement Fund | 5,949 | $1.54M | 0.02% | +53+0.9% | Added |
| Arizona State Retirement System | 5,973 | $1.54M | 0.01% | −65−1.1% | Reduced |
| Sanctuary Advisors, LLC | 6,030 | $1.56M | 0.01% | +6,030 | New |
| Cetera Investment Advisers | 6,206 | $1.60M | 0.00% | +1,590+34.4% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 6,229 | $1.61M | 0.00% | +1,143+22.5% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,382 | $1.65M | 0.01% | −7−0.1% | Reduced |
| STRS Ohio | 6,400 | $1.65M | 0.01% | −100−1.5% | Reduced |
| Teachers Retirement System of the State of Kentucky | 6,458 | $1.67M | 0.01% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 6,747 | $1.74M | 0.01% | 00.0% | Unchanged |
| Legato Capital Management LLC | 6,973 | $1.80M | 0.16% | +5,060+264.5% | Added |
| Yousif Capital Management, LLC | 7,131 | $1.84M | 0.02% | −36−0.5% | Reduced |
| Quantum Private Wealth, LLC | 7,181 | $1.85M | 0.57% | 00.0% | Unchanged |
| Martingale Asset Management L P | 7,208 | $1.86M | 0.05% | +2,702+60.0% | Added |
| Decheng Capital LLC | 7,300 | $1.89M | 0.29% | −10,000−57.8% | Reduced |
| Amalgamated Bank | 7,379 | $1.91M | 0.01% | −107−1.4% | Reduced |
| State of New Jersey Common Pension Fund D | 7,433 | $1.92M | 0.01% | +24+0.3% | Added |
| XTX Topco Ltd | 7,479 | $1.93M | 0.03% | +7,479 | New |
| Tealwood Asset Management Inc | 7,664 | $1.98M | 0.90% | −49−0.6% | Reduced |
| Aquatic Capital Management LLC | 8,257 | $2.13M | 0.06% | +8,257 | New |
| Erste Asset Management GmbH | 8,700 | $2.15M | 0.02% | +3,000+52.6% | Added |
| Clough Capital Partners L P | 8,502 | $2.20M | 0.21% | +696+8.9% | Added |
| Profund Advisors LLC | 8,790 | $2.27M | 0.08% | −1,097−11.1% | Reduced |
| Susquehanna International Group, LLP | 9,042 | $2.34M | 0.00% | +7,175+384.3% | Added |
| Brown Capital Management LLC | 9,247 | $2.39M | 0.34% | +9,247 | New |
| Virginia Retirement Systems Et Al | 9,500 | $2.45M | 0.02% | +500+5.6% | Added |
| Renaissance Technologies LLC | 9,600 | $2.48M | 0.00% | +6,300+190.9% | Added |
| Nomura Asset Management International Inc. | 10,218 | $2.64M | 0.00% | +627+6.5% | Added |
| Wellington Management Group LLP | 10,227 | $2.64M | 0.00% | −424−4.0% | Reduced |
| State of Tennessee, Treasury Department | 10,254 | $2.65M | 0.01% | +61+0.6% | Added |
| Atika Capital Management LLC | 10,625 | $2.74M | 0.43% | +10,625 | New |
| Privium Fund Management B.V. | 11,170 | $2.89M | 0.60% | −1,000−8.2% | Reduced |
| Vanguard Global Advisers, LLC | 11,276 | $2.91M | 0.00% | +11,276 | New |
| Louisiana State Employees Retirement System | 11,400 | $2.94M | 0.05% | −400−3.4% | Reduced |
| Commonwealth Equity Services, LLC | 11,591 | $2.99M | 0.00% | +1,704+17.2% | Added |
| Envestnet Asset Management Inc | 11,983 | $3.10M | 0.00% | +1,406+13.3% | Added |
| Torray LLC | 12,032 | $3.11M | 0.46% | +47+0.4% | Added |
| Bridge City Capital, LLC | 12,045 | $3.11M | 0.86% | −90−0.7% | Reduced |
| Natixis Advisors, L.P. | 12,125 | $3.13M | 0.00% | +443+3.8% | Added |
| Evolutionary Tree Capital Management, LLC | 12,314 | $3.18M | 5.98% | −4,497−26.8% | Reduced |
| Credit Agricole S A | 12,976 | $3.35M | 0.01% | 00.0% | Unchanged |
| Intech Investment Management LLC | 13,520 | $3.49M | 0.03% | +3,769+38.7% | Added |
| MetLife Investment Management | 13,542 | $3.50M | 0.02% | −302−2.2% | Reduced |
| AQR Capital Management LLC | 14,114 | $3.65M | 0.00% | −43−0.3% | Reduced |
| Illinois Municipal Retirement Fund | 14,151 | $3.66M | 0.05% | +1,452+11.4% | Added |
| Tudor Investment Corp Et Al | 14,476 | $3.74M | 0.02% | +13,101+952.8% | Added |
| Wells Fargo & Company | 14,988 | $3.87M | 0.00% | −16,584−52.5% | Reduced |
| Cim, LLC | 14,990 | $3.87M | 0.56% | +14,990 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 15,121 | $3.89M | 0.01% | +2,167+16.7% | Added |
| New York State Teachers Retirement System | 15,637 | $4.04M | 0.01% | −13−0.1% | Reduced |
| State Board of Administration of Florida Retirement System | 15,756 | $4.07M | 0.01% | 00.0% | Unchanged |
| Creative Planning | 15,937 | $4.12M | 0.00% | +2,056+14.8% | Added |
| EAM Investors, LLC | 16,483 | $4.26M | 0.49% | −8,184−33.2% | Reduced |
| Rhenman & Partners Asset Management AB | 16,675 | $4.31M | 0.53% | −8,325−33.3% | Reduced |
| Thrivent Financial for Lutherans | 17,226 | $4.45M | 0.01% | −508−2.9% | Reduced |
| State of Alaska, Department of Revenue | 17,484 | $4.51M | 0.05% | −418−2.3% | Reduced |
| Rafferty Asset Management, LLC | 17,687 | $4.57M | 0.02% | −6,581−27.1% | Reduced |
| Campbell & CO Investment Adviser LLC | 17,795 | $4.60M | 0.26% | +17,795 | New |
| Zacks Investment Management | 17,919 | $4.63M | 0.04% | +17,919 | New |
| Lisanti Capital Growth, LLC | 18,515 | $4.78M | 1.21% | +18,515 | New |
| GW&K Investment Management, LLC | 19,245 | $4.97M | 0.04% | −336−1.7% | Reduced |
| Polygon Management Ltd. | 19,668 | $5.08M | 1.00% | +7,854+66.5% | Added |
| ADAR1 Capital Management, LLC | 20,014 | $5.17M | 0.31% | 00.0% | Unchanged |
| EFG International AG | 20,049 | $5.18M | 0.11% | −3,520−14.9% | Reduced |
| Pinnacle Financial Partners, Inc. | 20,180 | $5.21M | 0.04% | +3,197+18.8% | Added |
| Bessemer Group Inc | 20,285 | $5.24M | 0.01% | +25+0.1% | Added |
| Vanguard Asset Management, Ltd | 20,606 | $5.32M | 0.00% | +20,606 | New |
| State of Wisconsin Investment Board | 20,691 | $5.34M | 0.01% | +6,225+43.0% | Added |
| Great West Life Assurance Co | 21,413 | $5.53M | 0.01% | −674−3.1% | Reduced |
| Elmind Capital, LP | 22,000 | $5.68M | 1.61% | 00.0% | Unchanged |
| Fiera Capital Corp | 24,146 | $6.24M | 0.02% | +5,289+28.0% | Added |
| Granite Investment Partners, LLC | 24,284 | $6.27M | 0.39% | −1,476−5.7% | Reduced |
| Deutsche Bank AG | 24,831 | $6.41M | 0.00% | +2,381+10.6% | Added |
| California State Teachers Retirement System | 26,186 | $6.76M | 0.01% | +5,603+27.2% | Added |
| Russell Investments Group, Ltd. | 26,210 | $6.77M | 0.01% | −2,744−9.5% | Reduced |
| HealthInvest Partners AB | 37,579 | $6.79M | 2.19% | +3,726+11.0% | Added |
| Fisher Asset Management, LLC | 27,784 | $7.18M | 0.00% | +23,998+633.9% | Added |
| Prudential Financial Inc | 29,638 | $7.66M | 0.01% | +2,623+9.7% | Added |
| Standard Life Aberdeen plc | 30,155 | $7.79M | 0.01% | −9,205−23.4% | Reduced |