Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- −21 vs. Q1 2025
- Shares held
- 27.7M
- +56.6K (+0.2%) vs. Q1 2025
- Total value
- $3.80B
- −$1.17B (−23.6%) vs. Q1 2025
- New holders
- 42
- 101 more added
- Sold out
- 63
- 96 more reduced
3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Synovus Financial Corp | 20,643 | $2.84M | 0.03% | +20,643 | New |
| Great West Life Assurance Co | 20,847 | $2.86M | 0.00% | −3,762−15.3% | Reduced |
| Biondo Investment Advisors, LLC | 21,240 | $2.92M | 0.38% | +21,240 | New |
| EFG Asset Management (North America) Corp. | 22,878 | $3.14M | 0.44% | +5,507+31.7% | Added |
| New York State Common Retirement Fund | 23,382 | $3.21M | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 24,680 | $3.39M | 0.00% | −7,686−23.7% | Reduced |
| Verition Fund Management LLC | 26,514 | $3.64M | 0.02% | +7,889+42.4% | Added |
| Los Angeles Capital Management LLC | 26,638 | $3.66M | 0.01% | +1,709+6.9% | Added |
| GW&K Investment Management, LLC | 30,175 | $4.15M | 0.04% | −3,925−11.5% | Reduced |
| Susquehanna International Group, LLP | 30,252 | $4.16M | 0.01% | −3,577−10.6% | Reduced |
| Man Group plc | 30,481 | $4.19M | 0.01% | +30,481 | New |
| Alliancebernstein L.P. | 31,120 | $4.28M | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 26,151 | $4.42M | 0.01% | −1,160−4.2% | Reduced |
| Citadel Advisors LLC | 34,560 | $4.75M | 0.00% | +34,464+35,900.0% | Added |
| Rafferty Asset Management, LLC | 34,665 | $4.77M | 0.02% | +10,504+43.5% | Added |
| State of Wisconsin Investment Board | 36,089 | $4.96M | 0.01% | +11,906+49.2% | Added |
| Kennedy Capital Management, Inc. | 38,146 | $5.24M | 0.13% | −3,372−8.1% | Reduced |
| Mutual of America Capital Management LLC | 38,357 | $5.27M | 0.06% | +1,926+5.3% | Added |
| Palisades Investment Partners, LLC | 40,203 | $5.53M | 2.42% | −493−1.2% | Reduced |
| CI Private Wealth, LLC | 40,538 | $5.57M | 0.01% | −1,589−3.8% | Reduced |
| Swiss National Bank | 41,400 | $5.69M | 0.00% | −400−1.0% | Reduced |
| Federated Hermes, Inc. | 42,743 | $5.88M | 0.01% | +29,962+234.4% | Added |
| Citigroup Inc | 52,533 | $7.22M | 0.01% | −20,992−28.6% | Reduced |
| Alyeska Investment Group, L.P. | 53,934 | $7.41M | 0.03% | +53,934 | New |
| Skandinaviska Enskilda Banken AB (publ) | 59,978 | $8.24M | 0.04% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 62,835 | $8.64M | 0.00% | +2,327+3.8% | Added |
| Voya Investment Management LLC | 63,993 | $8.80M | 0.01% | −608−0.9% | Reduced |
| Decheng Capital LLC | 66,000 | $9.07M | 2.29% | +1,000+1.5% | Added |
| Handelsbanken Fonder AB | 66,800 | $9.18M | 0.03% | −7,500−10.1% | Reduced |
| Legal & General Group Plc | 68,393 | $9.40M | 0.00% | +1,884+2.8% | Added |
| Raymond James Financial Inc | 68,735 | $9.45M | 0.00% | +2,774+4.2% | Added |
| Rhumbline Advisers | 70,753 | $9.73M | 0.01% | +2,026+2.9% | Added |
| Invesco Ltd. | 70,888 | $9.74M | 0.00% | −183,598−72.1% | Reduced |
| Victory Capital Management Inc | 80,123 | $11.0M | 0.01% | +7,308+10.0% | Added |
| C WorldWide Group Holding A/S | 85,809 | $11.8M | 0.16% | 00.0% | Unchanged |
| Public Sector Pension Investment Board | 86,688 | $11.9M | 0.05% | +6,424+8.0% | Added |
| Renaissance Technologies LLC | 89,800 | $12.3M | 0.02% | +78,600+701.8% | Added |
| William Blair Investment Management, LLC | 91,099 | $12.5M | 0.03% | +91,099 | New |
| JPMorgan Chase & Co | 91,153 | $12.5M | 0.00% | −9,621−9.5% | Reduced |
| Barclays PLC | 92,871 | $12.8M | 0.01% | +47,874+106.4% | Added |
| UBS Group AG | 97,240 | $13.4M | 0.00% | +16,121+19.9% | Added |
| Logos Global Management LP | 100,000 | $13.7M | 1.84% | +100,000 | New |
| Standard Life Aberdeen plc | 108,518 | $14.9M | 0.03% | +71,217+190.9% | Added |
| S Squared Technology, LLC | 109,215 | $15.0M | 6.33% | +12,000+12.3% | Added |
| Marshall Wace, LLP | 112,382 | $15.4M | 0.02% | +95,158+552.5% | Added |
| TimesSquare Capital Management, LLC | 114,204 | $15.7M | 0.23% | −27,979−19.7% | Reduced |
| Bank of America Corp | 121,812 | $16.7M | 0.00% | +29,251+31.6% | Added |
| Pictet Asset Management Holding SA | 130,537 | $17.9M | 0.02% | +65,275+100.0% | Added |
| Principal Financial Group Inc | 140,883 | $19.4M | 0.01% | +14,546+11.5% | Added |
| Readystate Asset Management LP | 147,980 | $20.3M | 0.84% | +147,980 | New |
| Segall Bryant & Hamill, LLC | 148,614 | $20.4M | 0.29% | +3,277+2.3% | Added |
| Woodline Partners LP | 150,616 | $20.7M | 0.11% | −71,427−32.2% | Reduced |
| Bank of New York Mellon Corp | 160,517 | $22.1M | 0.00% | −8,662−5.1% | Reduced |
| Nuveen, LLC | 188,019 | $25.8M | 0.01% | −46,161−19.7% | Reduced |
| First Trust Advisors LP | 222,370 | $30.6M | 0.02% | +189,245+571.3% | Added |
| UBS Asset Management Americas Inc | 234,320 | $32.2M | 0.01% | −341,186−59.3% | Reduced |
| Morgan Stanley | 234,421 | $32.2M | 0.00% | −63,784−21.4% | Reduced |
| Charles Schwab Investment Management Inc | 246,180 | $33.8M | 0.01% | −4,334−1.7% | Reduced |
| Northern Trust Corp | 251,408 | $34.6M | 0.00% | −8,587−3.3% | Reduced |
| Price T Rowe Associates Inc | 261,383 | $35.9M | 0.00% | −149,478−36.4% | Reduced |
| Norges Bank | 282,706 | $38.9M | 0.00% | +9,497+3.5% | Added |
| Dimensional Fund Advisors LP | 505,889 | $69.5M | 0.02% | −28,030−5.2% | Reduced |
| Goldman Sachs Group Inc | 530,361 | $72.9M | 0.01% | +296,721+127.0% | Added |
| Hood River Capital Management LLC | 533,023 | $73.3M | 1.02% | +8,379+1.6% | Added |
| Geode Capital Management, LLC | 619,547 | $85.2M | 0.01% | +7,194+1.2% | Added |
| Redmile Group, LLC | 663,471 | $91.2M | 9.71% | −74,204−10.1% | Reduced |
| Frazier Life Sciences Management, L.P. | 688,460 | $94.6M | 3.78% | 00.0% | Unchanged |
| Braidwell LP | 727,811 | $100.0M | 3.42% | +327,067+81.6% | Added |
| Soleus Capital Management, L.P. | 922,958 | $126.9M | 8.76% | +481,200+108.9% | Added |
| Capital World Investors | 942,249 | $129.5M | 0.02% | −12,219−1.3% | Reduced |
| State Street Corp | 1,355,346 | $186.3M | 0.01% | +128,639+10.5% | Added |
| Avoro Capital Advisors LLC | 2,660,000 | $365.6M | 6.40% | −71,000−2.6% | Reduced |
| Vanguard Group Inc | 2,822,888 | $388.0M | 0.01% | −2,394−0.1% | Reduced |
| BlackRock, Inc. | 3,845,155 | $528.6M | 0.01% | −98,010−2.5% | Reduced |
| FMR LLC | 4,334,761 | $595.9M | 0.03% | +13,929+0.3% | Added |
| T. Rowe Price Investment Management, Inc. | 0 | $0 | 0.00% | −185,550−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −151,225−100.0% | Sold out |
| 1832 Asset Management L.P. | 0 | $0 | 0.00% | −136,000−100.0% | Sold out |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −95,781−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −81,999−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Oberweis Asset Management Inc | 0 | $0 | 0.00% | −46,800−100.0% | Sold out |
| Jennison Associates LLC | 0 | $0 | 0.00% | −33,594−100.0% | Sold out |
| Beacon Harbor Wealth Advisors, Inc. | 0 | $0 | 0.00% | −32,235−100.0% | Sold out |
| Lisanti Capital Growth, LLC | 0 | $0 | 0.00% | −30,410−100.0% | Sold out |
| Castleark Management LLC | 0 | $0 | 0.00% | −26,120−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −23,663−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −18,624−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −13,122−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −12,970−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −9,952−100.0% | Sold out |
| Jackson Creek Investment Advisors LLC | 0 | $0 | 0.00% | −8,048−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −7,274−100.0% | Sold out |
| Legato Capital Management LLC | 0 | $0 | 0.00% | −5,190−100.0% | Sold out |
| Gotham Asset Management, LLC | 0 | $0 | 0.00% | −4,804−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −4,680−100.0% | Sold out |
| Prime Capital Investment Advisors, LLC | 0 | $0 | 0.00% | −4,504−100.0% | Sold out |
| Eschler Asset Management LLP | 0 | $0 | 0.00% | −4,403−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −4,200−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −3,883−100.0% | Sold out |