Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 299
- +37 vs. Q4 2024
- Shares held
- 27.6M
- +139.0K (+0.5%) vs. Q4 2024
- Total value
- $4.98B
- +$673.8M (+15.7%) vs. Q4 2024
- New holders
- 64
- 88 more added
- Sold out
- 27
- 112 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| MetLife Investment Management | 14,524 | $2.62M | 0.01% | −473−3.2% | Reduced |
| Fiera Capital Corp | 15,645 | $2.82M | 0.01% | −28−0.2% | Reduced |
| DekaBank Deutsche Girozentrale | 15,503 | $2.82M | 0.01% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 15,893 | $2.87M | 0.01% | +688+4.5% | Added |
| New York State Teachers Retirement System | 15,979 | $2.88M | 0.01% | +100+0.6% | Added |
| Fieldview Capital Management, LLC | 16,342 | $2.95M | 0.42% | +16,342 | New |
| Wells Fargo & Company | 17,135 | $3.09M | 0.00% | +207+1.2% | Added |
| Marshall Wace, LLP | 17,224 | $3.11M | 0.00% | +6,893+66.7% | Added |
| EFG Asset Management (North America) Corp. | 17,371 | $3.13M | 0.52% | −343−1.9% | Reduced |
| Rhenman & Partners Asset Management AB | 17,750 | $3.20M | 0.37% | −6,000−25.3% | Reduced |
| Erste Asset Management GmbH | 18,200 | $3.35M | 0.04% | 00.0% | Unchanged |
| Thrivent Financial for Lutherans | 18,590 | $3.35M | 0.01% | −973−5.0% | Reduced |
| Schonfeld Strategic Advisors LLC | 18,624 | $3.36M | 0.02% | +11,020+144.9% | Added |
| Verition Fund Management LLC | 18,625 | $3.36M | 0.02% | −6,277−25.2% | Reduced |
| SEI Investments Co | 18,691 | $3.37M | 0.00% | −2,473−11.7% | Reduced |
| Franklin Resources Inc | 19,013 | $3.43M | 0.00% | −165,014−89.7% | Reduced |
| California State Teachers Retirement System | 20,126 | $3.63M | 0.00% | −262−1.3% | Reduced |
| Deutsche Bank AG | 21,737 | $3.92M | 0.00% | −3,624−14.3% | Reduced |
| New York State Common Retirement Fund | 23,382 | $4.22M | 0.01% | 00.0% | Unchanged |
| HealthInvest Partners AB | 23,491 | $4.24M | 1.87% | +14,289+155.3% | Added |
| OrbiMed Advisors LLC | 23,500 | $4.24M | 0.10% | 00.0% | Unchanged |
| Jane Street Group, LLC | 23,663 | $4.27M | 0.01% | −12,192−34.0% | Reduced |
| Rafferty Asset Management, LLC | 24,161 | $4.36M | 0.02% | −3,040−11.2% | Reduced |
| State of Wisconsin Investment Board | 24,183 | $4.36M | 0.01% | −319−1.3% | Reduced |
| Great West Life Assurance Co | 24,609 | $4.43M | 0.01% | −2,145−8.0% | Reduced |
| Los Angeles Capital Management LLC | 24,929 | $4.49M | 0.02% | +15,045+152.2% | Added |
| Castleark Management LLC | 26,120 | $4.71M | 0.16% | +26,120 | New |
| Prudential Financial Inc | 27,311 | $4.92M | 0.01% | −13,882−33.7% | Reduced |
| Lisanti Capital Growth, LLC | 30,410 | $5.48M | 1.63% | +30,410 | New |
| Alliancebernstein L.P. | 31,120 | $5.61M | 0.00% | 00.0% | Unchanged |
| Beacon Harbor Wealth Advisors, Inc. | 32,235 | $5.81M | 1.35% | +32,235 | New |
| Manufacturers Life Insurance Company, The | 32,366 | $5.84M | 0.01% | −2,840−8.1% | Reduced |
| First Trust Advisors LP | 33,125 | $5.97M | 0.01% | +9,956+43.0% | Added |
| Jennison Associates LLC | 33,594 | $6.06M | 0.00% | −269,927−88.9% | Reduced |
| Susquehanna International Group, LLP | 33,829 | $6.10M | 0.01% | −4,639−12.1% | Reduced |
| GW&K Investment Management, LLC | 34,100 | $6.15M | 0.06% | −830−2.4% | Reduced |
| Mutual of America Capital Management LLC | 36,431 | $6.57M | 0.08% | −87−0.2% | Reduced |
| Standard Life Aberdeen plc | 37,301 | $6.73M | 0.01% | −19,732−34.6% | Reduced |
| Russell Investments Group, Ltd. | 37,781 | $6.81M | 0.01% | +37,336+8,390.1% | Added |
| TD Asset Management Inc | 40,268 | $7.26M | 0.01% | −3,212−7.4% | Reduced |
| Palisades Investment Partners, LLC | 40,696 | $7.34M | 3.68% | +217+0.5% | Added |
| Kennedy Capital Management, Inc. | 41,518 | $7.49M | 0.18% | +13,807+49.8% | Added |
| Swiss National Bank | 41,800 | $7.54M | 0.01% | −600−1.4% | Reduced |
| CI Private Wealth, LLC | 42,127 | $7.60M | 0.01% | −882−2.1% | Reduced |
| Barclays PLC | 44,997 | $8.11M | 0.00% | −7,432−14.2% | Reduced |
| Janney Montgomery Scott LLC | 45,935 | $8.28M | 0.02% | −6,657−12.7% | Reduced |
| Oberweis Asset Management Inc | 46,800 | $8.44M | 0.42% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 49,892 | $9.00M | 0.01% | +42,465+571.8% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 59,978 | $10.8M | 0.05% | −29,069−32.6% | Reduced |
| Integral Health Asset Management, LLC | 60,000 | $10.8M | 1.20% | +5,000+9.1% | Added |
| Millennium Management LLC | 60,388 | $10.9M | 0.01% | +41,432+218.6% | Added |
| Ameriprise Financial Inc | 60,508 | $10.9M | 0.00% | −52,968−46.7% | Reduced |
| Voya Investment Management LLC | 64,601 | $11.6M | 0.01% | −10,100−13.5% | Reduced |
| Decheng Capital LLC | 65,000 | $11.7M | 3.29% | −11,772−15.3% | Reduced |
| Pictet Asset Management Holding SA | 65,262 | $11.8M | 0.01% | −46,827−41.8% | Reduced |
| Raymond James Financial Inc | 65,961 | $11.9M | 0.00% | −36,100−35.4% | Reduced |
| Legal & General Group Plc | 66,509 | $12.0M | 0.00% | −2,916−4.2% | Reduced |
| Rhumbline Advisers | 68,727 | $12.4M | 0.01% | −409−0.6% | Reduced |
| Victory Capital Management Inc | 72,815 | $13.1M | 0.01% | −8,513−10.5% | Reduced |
| Citigroup Inc | 73,525 | $13.3M | 0.01% | −26,108−26.2% | Reduced |
| Handelsbanken Fonder AB | 74,300 | $13.4M | 0.06% | −11,000−12.9% | Reduced |
| Public Sector Pension Investment Board | 80,264 | $14.5M | 0.06% | +17,254+27.4% | Added |
| UBS Group AG | 81,119 | $14.6M | 0.00% | −19,012−19.0% | Reduced |
| Squarepoint Ops LLC | 81,999 | $14.8M | 0.04% | +72,440+757.8% | Added |
| C WorldWide Group Holding A/S | 85,809 | $15.5M | 0.19% | −20,000−18.9% | Reduced |
| Bank of America Corp | 92,561 | $16.7M | 0.00% | +16,762+22.1% | Added |
| Eventide Asset Management, LLC | 95,781 | $17.3M | 0.34% | 00.0% | Unchanged |
| S Squared Technology, LLC | 97,215 | $17.5M | 8.97% | +2,000+2.1% | Added |
| JPMorgan Chase & Co | 100,774 | $18.2M | 0.00% | −51,061−33.6% | Reduced |
| Principal Financial Group Inc | 126,337 | $22.8M | 0.01% | +2,884+2.3% | Added |
| 1832 Asset Management L.P. | 136,000 | $24.5M | 0.05% | +136,000 | New |
| TimesSquare Capital Management, LLC | 142,183 | $25.6M | 0.41% | −16,685−10.5% | Reduced |
| Segall Bryant & Hamill, LLC | 145,337 | $26.2M | 0.40% | −3,972−2.7% | Reduced |
| Lord, Abbett & Co. LLC | 151,225 | $27.3M | 0.10% | −64,403−29.9% | Reduced |
| Bank of New York Mellon Corp | 169,179 | $30.5M | 0.01% | −167−0.1% | Reduced |
| T. Rowe Price Investment Management, Inc. | 185,550 | $33.5M | 0.02% | +185,550 | New |
| Woodline Partners LP | 222,043 | $40.0M | 0.26% | +941+0.4% | Added |
| Goldman Sachs Group Inc | 233,640 | $42.1M | 0.01% | −43,535−15.7% | Reduced |
| Nuveen, LLC | 234,180 | $42.2M | 0.01% | +234,180 | New |
| Charles Schwab Investment Management Inc | 250,514 | $45.2M | 0.01% | +7,344+3.0% | Added |
| Invesco Ltd. | 254,486 | $45.9M | 0.01% | −20,709−7.5% | Reduced |
| Northern Trust Corp | 259,995 | $46.9M | 0.01% | −2,268−0.9% | Reduced |
| Norges Bank | 273,209 | $49.3M | 0.01% | +53,681+24.5% | Added |
| Morgan Stanley | 298,205 | $53.8M | 0.00% | +41,930+16.4% | Added |
| Braidwell LP | 400,744 | $72.3M | 2.54% | +200,244+99.9% | Added |
| Price T Rowe Associates Inc | 410,861 | $74.1M | 0.01% | −98,598−19.4% | Reduced |
| Soleus Capital Management, L.P. | 441,758 | $79.6M | 6.25% | +83,379+23.3% | Added |
| Hood River Capital Management LLC | 524,644 | $94.6M | 1.61% | +11,918+2.3% | Added |
| Dimensional Fund Advisors LP | 533,919 | $96.3M | 0.02% | −54,680−9.3% | Reduced |
| UBS Asset Management Americas Inc | 575,506 | $103.8M | 0.03% | +365,304+173.8% | Added |
| Geode Capital Management, LLC | 612,353 | $110.4M | 0.01% | +20,757+3.5% | Added |
| Frazier Life Sciences Management, L.P. | 688,460 | $124.1M | 5.67% | −100,000−12.7% | Reduced |
| Redmile Group, LLC | 737,675 | $133.0M | 12.57% | −15,500−2.1% | Reduced |
| Capital World Investors | 954,468 | $172.1M | 0.03% | +75,265+8.6% | Added |
| State Street Corp | 1,226,707 | $221.2M | 0.01% | −52,268−4.1% | Reduced |
| Avoro Capital Advisors LLC | 2,731,000 | $492.4M | 7.69% | +102,178+3.9% | Added |
| Vanguard Group Inc | 2,825,282 | $509.4M | 0.01% | −53,169−1.8% | Reduced |
| BlackRock, Inc. | 3,943,165 | $711.0M | 0.02% | −90,707−2.2% | Reduced |
| FMR LLC | 4,320,832 | $779.0M | 0.05% | +6,818+0.2% | Added |
| Baker Bros. Advisors LP | 0 | $0 | 0.00% | −169,934−100.0% | Sold out |