Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 264
- −15 vs. Q3 2024
- Shares held
- 27.8M
- −399.3K (−1.4%) vs. Q3 2024
- Total value
- $4.35B
- −$775.6M (−15.1%) vs. Q3 2024
- New holders
- 37
- 95 more added
- Sold out
- 52
- 97 more reduced
4 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | 35,206 | $5.52M | 0.00% | +3,981+12.7% | Added |
| Jane Street Group, LLC | 35,855 | $5.62M | 0.01% | +17,674+97.2% | Added |
| Mutual of America Capital Management LLC | 36,518 | $5.72M | 0.06% | −48−0.1% | Reduced |
| Susquehanna International Group, LLP | 38,468 | $6.03M | 0.01% | +28,914+302.6% | Added |
| Palisades Investment Partners, LLC | 40,479 | $6.34M | 2.68% | +3,436+9.3% | Added |
| Swiss National Bank | 42,400 | $6.64M | 0.00% | +3,300+8.4% | Added |
| CI Private Wealth, LLC | 43,009 | $6.74M | 0.01% | −4,678−9.8% | Reduced |
| TD Asset Management Inc | 43,480 | $6.81M | 0.01% | +10,000+29.9% | Added |
| Prudential Financial Inc | 41,193 | $6.82M | 0.01% | +3,254+8.6% | Added |
| Oberweis Asset Management Inc | 46,800 | $7.33M | 0.35% | 00.0% | Unchanged |
| Barclays PLC | 52,429 | $8.21M | 0.00% | −4,111−7.3% | Reduced |
| Janney Montgomery Scott LLC | 52,592 | $8.24M | 0.02% | +15,545+42.0% | Added |
| Integral Health Asset Management, LLC | 55,000 | $8.62M | 0.76% | +55,000 | New |
| Standard Life Aberdeen plc | 57,033 | $8.93M | 0.02% | +13,979+32.5% | Added |
| Public Sector Pension Investment Board | 63,010 | $9.87M | 0.04% | +9,354+17.4% | Added |
| Rhumbline Advisers | 69,136 | $10.8M | 0.01% | −1,173−1.7% | Reduced |
| Legal & General Group Plc | 69,425 | $10.9M | 0.00% | +3,170+4.8% | Added |
| Voya Investment Management LLC | 74,701 | $11.7M | 0.01% | +4,123+5.8% | Added |
| Bank of America Corp | 75,799 | $11.9M | 0.00% | −28,855−27.6% | Reduced |
| Decheng Capital LLC | 76,772 | $12.0M | 2.58% | +5,000+7.0% | Added |
| Victory Capital Management Inc | 81,328 | $12.7M | 0.01% | −16,957−17.3% | Reduced |
| Handelsbanken Fonder AB | 85,300 | $13.4M | 0.05% | −9,400−9.9% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 89,047 | $14.2M | 0.06% | −37,035−29.4% | Reduced |
| S Squared Technology, LLC | 95,215 | $14.9M | 6.20% | +20,000+26.6% | Added |
| Eventide Asset Management, LLC | 95,781 | $15.0M | 0.27% | 00.0% | Unchanged |
| Citigroup Inc | 99,633 | $15.6M | 0.02% | +64,549+184.0% | Added |
| UBS Group AG | 100,131 | $15.7M | 0.00% | +63,802+175.6% | Added |
| Raymond James Financial Inc | 102,061 | $16.0M | 0.01% | +102,061 | New |
| C WorldWide Group Holding A/S | 105,809 | $16.6M | 0.20% | −30,000−22.1% | Reduced |
| Pictet Asset Management Holding SA | 112,089 | $17.6M | 0.02% | −3,261−2.8% | Reduced |
| Ameriprise Financial Inc | 113,476 | $17.8M | 0.00% | +23,727+26.4% | Added |
| Driehaus Capital Management LLC | 121,702 | $19.1M | 0.16% | −41,602−25.5% | Reduced |
| Principal Financial Group Inc | 123,453 | $19.3M | 0.01% | +3,727+3.1% | Added |
| Segall Bryant & Hamill, LLC | 149,309 | $23.4M | 0.32% | −7,835−5.0% | Reduced |
| JPMorgan Chase & Co | 151,835 | $23.8M | 0.00% | +23,934+18.7% | Added |
| TimesSquare Capital Management, LLC | 158,868 | $24.9M | 0.36% | +44,646+39.1% | Added |
| Bank of New York Mellon Corp | 169,346 | $26.5M | 0.00% | −2,307−1.3% | Reduced |
| Baker Bros. Advisors LP | 169,934 | $26.6M | 0.28% | 00.0% | Unchanged |
| Franklin Resources Inc | 184,027 | $28.8M | 0.01% | −59,733−24.5% | Reduced |
| Braidwell LP | 200,500 | $31.4M | 0.93% | +31,809+18.9% | Added |
| UBS Asset Management Americas Inc | 210,202 | $32.9M | 0.01% | −14,743−6.6% | Reduced |
| Lord, Abbett & Co. LLC | 215,628 | $33.8M | 0.11% | −68,531−24.1% | Reduced |
| Norges Bank | 219,528 | $34.4M | 0.00% | −24,569−10.1% | Reduced |
| Woodline Partners LP | 221,102 | $34.6M | 0.23% | +41,287+23.0% | Added |
| Charles Schwab Investment Management Inc | 243,170 | $38.1M | 0.01% | +2,954+1.2% | Added |
| Morgan Stanley | 256,275 | $40.1M | 0.00% | −19,529−7.1% | Reduced |
| Northern Trust Corp | 262,263 | $41.1M | 0.01% | +23,572+9.9% | Added |
| Invesco Ltd. | 275,195 | $43.1M | 0.01% | −90,356−24.7% | Reduced |
| Goldman Sachs Group Inc | 277,175 | $43.4M | 0.01% | −24,179−8.0% | Reduced |
| Jennison Associates LLC | 303,521 | $47.5M | 0.03% | −106,536−26.0% | Reduced |
| Nuveen Asset Management, LLC | 304,115 | $47.6M | 0.01% | −7,740−2.5% | Reduced |
| Soleus Capital Management, L.P. | 358,379 | $56.1M | 4.25% | +141,400+65.2% | Added |
| Price T Rowe Associates Inc | 509,459 | $79.8M | 0.01% | +71,200+16.2% | Added |
| Hood River Capital Management LLC | 512,726 | $80.3M | 1.19% | +10,622+2.1% | Added |
| Dimensional Fund Advisors LP | 588,599 | $92.2M | 0.02% | −11,662−1.9% | Reduced |
| Geode Capital Management, LLC | 591,596 | $92.7M | 0.01% | −350.0% | Reduced |
| Redmile Group, LLC | 753,175 | $118.0M | 8.22% | −57,070−7.0% | Reduced |
| Frazier Life Sciences Management, L.P. | 788,460 | $123.5M | 5.13% | −200,000−20.2% | Reduced |
| Capital World Investors | 879,203 | $137.7M | 0.02% | +1200.0% | Added |
| State Street Corp | 1,278,975 | $200.4M | 0.01% | −173,836−12.0% | Reduced |
| Avoro Capital Advisors LLC | 2,628,822 | $411.8M | 5.83% | +6,600+0.3% | Added |
| Vanguard Group Inc | 2,878,451 | $450.9M | 0.01% | +28,707+1.0% | Added |
| BlackRock, Inc. | 4,033,872 | $631.9M | 0.01% | +40,749+1.0% | Added |
| FMR LLC | 4,314,014 | $675.8M | 0.04% | +21,133+0.5% | Added |
| First Turn Management, LLC | 0 | $0 | 0.00% | −67,942−100.0% | Sold out |
| Rock Springs Capital Management LP | 0 | $0 | 0.00% | −55,861−100.0% | Sold out |
| EAM Global Investors LLC | 0 | $0 | 0.00% | −28,976−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −27,939−100.0% | Sold out |
| Castleark Management LLC | 0 | $0 | 0.00% | −27,290−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −22,372−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −13,724−100.0% | Sold out |
| EAM Investors, LLC | 0 | $0 | 0.00% | −12,858−100.0% | Sold out |
| Summit Trail Advisors, LLC | 0 | $0 | 0.00% | −10,401−100.0% | Sold out |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −4,166−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −3,925−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −3,261−100.0% | Sold out |
| Everence Capital Management Inc | 0 | $0 | 0.00% | −3,060−100.0% | Sold out |
| Shaker Investments LLC | 0 | $0 | 0.00% | −2,920−100.0% | Sold out |
| Options Solutions, LLC | 0 | $0 | 0.00% | −2,699−100.0% | Sold out |
| Prime Capital Investment Advisors, LLC | 0 | $0 | 0.00% | −2,591−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −2,527−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −2,491−100.0% | Sold out |
| Alpha DNA Investment Management LLC | 0 | $0 | 0.00% | −2,332−100.0% | Sold out |
| Advantage Alpha Capital Partners LP | 0 | $0 | 0.00% | −2,289−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −2,280−100.0% | Sold out |
| Blueshift Asset Management, LLC | 0 | $0 | 0.00% | −1,823−100.0% | Sold out |
| Legato Capital Management LLC | 0 | $0 | 0.00% | −1,791−100.0% | Sold out |
| AlphaMark Advisors, LLC | 0 | $0 | 0.00% | −1,725−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −1,703−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −1,542−100.0% | Sold out |
| Wolverine Trading, LLC | 0 | $0 | 0.00% | −1,538−100.0% | Sold out |
| O'Shaughnessy Asset Management, LLC | 0 | $0 | 0.00% | −1,425−100.0% | Sold out |
| Veriti Management LLC | 0 | $0 | 0.00% | −1,385−100.0% | Sold out |
| CIBC Asset Management Inc | 0 | $0 | 0.00% | −1,378−100.0% | Sold out |
| Oppenheimer Asset Management Inc. | 0 | $0 | 0.00% | −1,289−100.0% | Sold out |
| Brinker Capital Investments, LLC | 0 | $0 | 0.00% | −1,247−100.0% | Sold out |
| Orion Portfolio Solutions, LLC | 0 | $0 | 0.00% | −1,247−100.0% | Sold out |
| Hilltop Holdings Inc. | 0 | $0 | 0.00% | −1,146−100.0% | Sold out |
| Ethic Inc. | 0 | $0 | 0.00% | −1,142−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −1,099−100.0% | Sold out |