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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
264
−15 vs. Q3 2024
Shares held
27.8M
−399.3K (−1.4%) vs. Q3 2024
Total value
$4.35B
−$775.6M (−15.1%) vs. Q3 2024
New holders
37
95 more added
Sold out
52
97 more reduced

4 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 264 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2024: $4.35B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2024.

Institutions holding KRYS in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Entropy Technologies, LP3,500$548.3K0.06%+3,500New
Main Management ETF Advisors, LLC3,560$558.0K0.03%−320−8.2%Reduced
Cynosure Management, LLC3,630$568.7K0.08%−359−9.0%Reduced
Pier 88 Investment Partners LLC3,750$587.5K0.12%+220+6.2%Added
Allianz Asset Management GmbH4,102$642.6K0.00%+1,500+57.6%Added
Hussman Strategic Advisors, Inc.4,200$658.0K0.19%+4,200New
HighVista Strategies LLC4,217$660.6K0.25%+4,217New
Pathstone Holdings, LLC4,252$666.2K0.00%−795−15.8%Reduced
CenterBook Partners LP4,283$671.0K0.04%+4,283New
KLP Kapitalforvaltning AS4,300$673.6K0.00%+4,300New
HSBC Holdings PLC4,519$717.7K0.00%+2,988+195.2%Added
Jain Global LLC4,800$752.0K0.02%+4,800New
Guggenheim Capital LLC4,862$761.7K0.01%+927+23.6%Added
Commonwealth Equity Services, LLC4,866$762.0K0.00%+190+4.1%Added
Bellevue Group AG5,047$790.7K0.02%+268+5.6%Added
Nicholas Investment Partners, LP5,086$796.8K0.07%−13,721−73.0%Reduced
Martingale Asset Management L P5,136$804.6K0.02%+10.0%Added
Police & Firemen's Retirement System of New Jersey5,283$827.6K0.01%+5,283New
Creative Planning5,397$845.5K0.00%−347−6.0%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys5,403$846.4K0.01%−10.0%Reduced
State Board of Administration of Florida Retirement System5,807$909.7K0.00%−60−1.0%Reduced
Oregon Public Employees Retirement Fund5,975$936.0K0.02%−5−0.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)6,054$948.4K0.00%+1,440+31.2%Added
China Universal Asset Management Co., Ltd.6,098$955.3K0.09%+572+10.4%Added
Arizona State Retirement System6,242$977.9K0.01%+487+8.5%Added
Profund Advisors LLC6,321$990.2K0.04%−3,664−36.7%Reduced
Teacher Retirement System of Texas6,383$1.00M0.00%+1,369+27.3%Added
Winton Group Ltd6,565$1.03M0.07%+1,274+24.1%Added
Ensign Peak Advisors, Inc6,569$1.03M0.00%00.0%Unchanged
Aquatic Capital Management LLC6,901$1.08M0.03%+6,901New
Tower Research Capital LLC (TRC)6,999$1.10M0.02%+6,912+7,944.8%Added
Quantum Private Wealth, LLC7,205$1.13M0.36%00.0%Unchanged
STRS Ohio7,300$1.14M0.00%+2,300+46.0%Added
D. E. Shaw & Co., Inc.7,427$1.16M0.00%−1,919−20.5%Reduced
Amalgamated Bank7,436$1.17M0.01%+20.0%Added
Blair William & Co7,443$1.17M0.00%+1,875+33.7%Added
Schonfeld Strategic Advisors LLC7,604$1.19M0.01%+1,153+17.9%Added
Perigon Wealth Management, LLC8,289$1.20M0.03%+123+1.5%Added
BNP Paribas Arbitrage, SA7,789$1.22M0.00%−2,644−25.3%Reduced
Jackson Creek Investment Advisors LLC8,052$1.26M0.38%−244−2.9%Reduced
CWM, LLC8,053$1.26M0.01%−5,793−41.8%Reduced
Maryland State Retirement & Pension System8,523$1.34M0.03%−15−0.2%Reduced
ProShare Advisors LLC8,848$1.39M0.00%+1,967+28.6%Added
Comerica Bank8,890$1.39M0.01%−207−2.3%Reduced
Teachers Retirement System of the State of Kentucky9,010$1.41M0.01%00.0%Unchanged
Zacks Investment Management9,078$1.42M0.01%−369−3.9%Reduced
Privium Fund Management B.V.9,250$1.45M0.33%+2,900+45.7%Added
AQR Capital Management LLC9,339$1.46M0.00%+989+11.8%Added
HealthInvest Partners AB9,202$1.47M0.70%00.0%Unchanged
Squarepoint Ops LLC9,559$1.50M0.00%−6,147−39.1%Reduced
ExodusPoint Capital Management, LP9,761$1.53M0.02%+9,761New
Yousif Capital Management, LLC9,777$1.53M0.02%−172−1.7%Reduced
Los Angeles Capital Management LLC9,884$1.55M0.01%00.0%Unchanged
Janus Henderson Group PLC10,071$1.58M0.00%+1,400+16.1%Added
Marshall Wace, LLP10,331$1.62M0.00%+10,331New
Evolutionary Tree Capital Management, LLC10,700$1.68M1.71%+1,588+17.4%Added
Intech Investment Management LLC10,839$1.70M0.02%+3,569+49.1%Added
Renaissance Technologies LLC10,900$1.71M0.00%−3,500−24.3%Reduced
Citadel Advisors LLC11,015$1.73M0.00%+10,919+11,374.0%Added
State of Tennessee, Treasury Department11,299$1.77M0.01%−263−2.3%Reduced
Redwood Investments, LLC11,343$1.78M0.48%−53−0.5%Reduced
Envestnet Asset Management Inc11,630$1.82M0.00%+121+1.1%Added
Wellington Management Group LLP11,704$1.83M0.00%−976−7.7%Reduced
State of New Jersey Common Pension Fund D11,803$1.85M0.01%+1,910+19.3%Added
Louisiana State Employees Retirement System12,200$1.91M0.04%00.0%Unchanged
Schroder Investment Management Group12,607$2.01M0.00%00.0%Unchanged
Federated Hermes, Inc.13,048$2.04M0.00%+229+1.8%Added
Corebridge Financial, Inc.13,225$2.07M0.01%−1,032−7.2%Reduced
Hennion & Walsh Asset Management, Inc.13,678$2.14M0.10%−232−1.7%Reduced
Illinois Municipal Retirement Fund14,146$2.22M0.03%+1,505+11.9%Added
State of Alaska, Department of Revenue14,423$2.26M0.03%−50.0%Reduced
MetLife Investment Management14,997$2.35M0.01%+680+4.7%Added
Mirae Asset Global ETFs Holdings Ltd.15,205$2.39M0.01%−181−1.2%Reduced
DekaBank Deutsche Girozentrale15,503$2.44M0.00%00.0%Unchanged
Fiera Capital Corp15,673$2.46M0.01%−527−3.3%Reduced
New York State Teachers Retirement System15,879$2.49M0.01%00.0%Unchanged
Wells Fargo & Company16,928$2.65M0.00%+2,972+21.3%Added
EFG Asset Management (North America) Corp.17,714$2.78M0.38%+4,185+30.9%Added
Erste Asset Management GmbH18,200$2.90M0.04%00.0%Unchanged
Millennium Management LLC18,956$2.97M0.00%−28,667−60.2%Reduced
Thrivent Financial for Lutherans19,563$3.06M0.01%−291−1.5%Reduced
California State Teachers Retirement System20,388$3.19M0.00%+1,127+5.9%Added
SEI Investments Co21,164$3.32M0.00%−13,085−38.2%Reduced
HRT Financial LP22,007$3.45M0.02%+22,007New
Caption Management, LLC22,339$3.50M0.14%+22,339New
First Trust Advisors LP23,169$3.63M0.00%−16,242−41.2%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH23,197$3.63M0.01%+23,197New
New York State Common Retirement Fund23,382$3.66M0.00%−2,481−9.6%Reduced
OrbiMed Advisors LLC23,500$3.68M0.08%00.0%Unchanged
Rhenman & Partners Asset Management AB23,750$3.72M0.38%+6,750+39.7%Added
Edgestream Partners, L.P.23,810$3.73M0.16%−8,447−26.2%Reduced
State of Wisconsin Investment Board24,502$3.84M0.01%+1,434+6.2%Added
Verition Fund Management LLC24,902$3.90M0.02%+8,902+55.6%Added
Deutsche Bank AG25,361$3.97M0.00%+9,750+62.5%Added
Great West Life Assurance Co26,754$4.19M0.01%−22−0.1%Reduced
Rafferty Asset Management, LLC27,201$4.26M0.02%−18,639−40.7%Reduced
Kennedy Capital Management, Inc.27,711$4.34M0.10%+22,517+433.5%Added
Allspring Global Investments Holdings, LLC29,777$4.66M0.01%−81,928−73.3%Reduced
Alliancebernstein L.P.31,120$4.88M0.00%+1,400+4.7%Added
GW&K Investment Management, LLC34,930$5.47M0.05%−1,099−3.1%Reduced