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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Bicycle Therapeutics PLC as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
103
+5 vs. Q1 2026
Shares held
37.3M
−203.9K (−0.5%) vs. Q1 2026
Total value
$157.9M
−$15.7M (−9.0%) vs. Q1 2026
New holders
18
34 more added
Sold out
13
18 more reduced

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 103 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ2 2026: $157.9M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q1 2026.

Institutions holding BCYC in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Armistice Capital, LLC3,398,000$14.4M0.40%00.0%Unchanged
FCPM III Services B.V.3,468,430$14.7M1.96%00.0%Unchanged
Baker Bros. Advisors LP10,885,357$46.2M0.23%00.0%Unchanged
Siren, L.L.C.0$00.00%−1,560,882−100.0%Sold out
Principal Financial Group Inc0$00.00%−1,174,625−100.0%Sold out
Silvercrest Asset Management Group LLC0$00.00%−428,684−100.0%Sold out
Platinum Investment Management Ltd0$00.00%−184,603−100.0%Sold out
Marex Group plc0$00.00%−115,000−100.0%Sold out
Man Group plc0$00.00%−63,305−100.0%Sold out
Engineers Gate Manager LP0$00.00%−35,400−100.0%Sold out
R Squared Ltd0$00.00%−21,057−100.0%Sold out
49 Wealth Management, LLC0$00.00%−14,317−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−10,879−100.0%Sold out
Legal & General Group Plc0$00.00%−9,054−100.0%Sold out
Basecamp Wealth Advisors LLC0$00.00%−167−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−5−100.0%Sold out