Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Bicycle Therapeutics PLC as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 109
- +11 vs. Q3 2025
- Shares held
- 39.2M
- +2.37M (+6.4%) vs. Q3 2025
- Total value
- $276.9M
- −$7.96M (−2.8%) vs. Q3 2025
- New holders
- 22
- 35 more added
- Sold out
- 11
- 29 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caitlin John, LLC | 2 | $14 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 5 | $35 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 6 | $42 | 0.00% | −1−14.3% | Reduced |
| EverSource Wealth Advisors, LLC | 6 | $42 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 29 | $205 | 0.00% | +29 | New |
| Daiwa Securities Group Inc. | 103 | $1.00K | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 167 | $1.18K | 0.00% | +167 | New |
| Winch Advisory Services, LLC | 172 | $1.22K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 200 | $1.42K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 218 | $1.54K | 0.00% | +218 | New |
| Jones Financial Companies LLLP | 250 | $1.77K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 316 | $2.24K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 435 | $3.08K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 562 | $3.98K | 0.00% | −1,710−75.3% | Reduced |
| GF Fund Management Co. Ltd. | 909 | $6.44K | 0.00% | −86−8.6% | Reduced |
| BNP Paribas Arbitrage, SA | 1,116 | $7.90K | 0.00% | +305+37.6% | Added |
| Citigroup Inc | 1,291 | $9.14K | 0.00% | −1,310−50.4% | Reduced |
| GAMMA Investing LLC | 1,386 | $9.81K | 0.00% | −730−34.5% | Reduced |
| Tower Research Capital LLC (TRC) | 1,668 | $11.8K | 0.00% | +3+0.2% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,248 | $15.9K | 0.00% | +461+25.8% | Added |
| Assetmark, Inc | 3,628 | $25.7K | 0.00% | +3+0.1% | Added |
| Natixis | 4,645 | $31.6K | 0.00% | +2,698+138.6% | Added |
| Clearstead Advisors, LLC | 4,655 | $33.0K | 0.00% | +3,262+234.2% | Added |
| FNY Investment Advisers, LLC | 7,486 | $53.0K | 0.02% | −3,014−28.7% | Reduced |
| China Universal Asset Management Co., Ltd. | 7,540 | $53.4K | 0.00% | −564−7.0% | Reduced |
| Legal & General Group Plc | 9,054 | $64.1K | 0.00% | −188,863−95.4% | Reduced |
| Skopos Labs, Inc. | 10,216 | $69.3K | 0.00% | +10,216 | New |
| Vontobel Holding Ltd. | 10,000 | $70.8K | 0.00% | +10,000 | New |
| Pinnacle Wealth Management Advisory Group, LLC | 10,000 | $70.8K | 0.00% | +10,000 | New |
| Invesco Ltd. | 10,092 | $71.5K | 0.00% | +10,092 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 10,116 | $71.6K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 10,682 | $76.0K | 0.00% | −2,051−16.1% | Reduced |
| Rhumbline Advisers | 11,171 | $79.1K | 0.00% | +7,896+241.1% | Added |
| Crossmark Global Holdings, Inc. | 11,399 | $80.7K | 0.00% | +9+0.1% | Added |
| Raymond James Financial Inc | 12,336 | $87.3K | 0.00% | +12,336 | New |
| Tocqueville Asset Management L.P. | 12,600 | $89.2K | 0.00% | +300+2.4% | Added |
| JustInvest LLC | 12,776 | $90.5K | 0.00% | −177−1.4% | Reduced |
| Cerity Partners LLC | 13,350 | $94.5K | 0.00% | −1,000−7.0% | Reduced |
| Forefront Analytics, LLC | 13,371 | $94.7K | 0.08% | +13,371 | New |
| Erste Asset Management GmbH | 14,000 | $94.9K | 0.00% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 13,792 | $97.6K | 0.00% | −604−4.2% | Reduced |
| The PNC Financial Services Group, Inc. | 14,138 | $100.1K | 0.00% | +1,058+8.1% | Added |
| Federation des caisses Desjardins du Quebec | 14,302 | $101.1K | 0.00% | 00.0% | Unchanged |
| Portland Investment Counsel Inc. | 15,000 | $106.2K | 0.03% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 18,355 | $130.0K | 0.00% | +10,228+125.9% | Added |
| Aquatic Capital Management LLC | 18,817 | $133.2K | 0.00% | +18,817 | New |
| Fox Run Management, L.L.C. | 19,771 | $140.0K | 0.02% | +19,771 | New |
| Simplex Trading, LLC | 19,986 | $141.5K | 0.00% | +19,986 | New |
| State of New Jersey Common Pension Fund D | 20,105 | $142.3K | 0.00% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 21,548 | $152.6K | 0.00% | +21,548 | New |
| Engineers Gate Manager LP | 24,047 | $170.3K | 0.00% | +10,626+79.2% | Added |
| Goldman Sachs Group Inc | 24,732 | $175.1K | 0.00% | +24,732 | New |
| Geode Capital Management, LLC | 25,129 | $177.9K | 0.00% | −14,796−37.1% | Reduced |
| UBS Group AG | 25,676 | $181.8K | 0.00% | +14,303+125.8% | Added |
| Woodstock Corp | 29,146 | $206.4K | 0.02% | +5,219+21.8% | Added |
| Jump Financial, LLC | 31,000 | $219.5K | 0.00% | +9,579+44.7% | Added |
| Virtus Investment Advisers, Inc. | 35,709 | $252.8K | 0.07% | +22,615+172.7% | Added |
| Marshall Wace, LLP | 38,795 | $274.7K | 0.00% | +38,795 | New |
| Harbor Capital Advisors, Inc. | 40,486 | $287.0K | 0.02% | −882−2.1% | Reduced |
| Alps Advisors Inc | 40,995 | $290.2K | 0.00% | +16,872+69.9% | Added |
| Man Group plc | 42,860 | $303.4K | 0.00% | +1,969+4.8% | Added |
| Quadrature Capital Ltd | 46,728 | $330.8K | 0.00% | +18,834+67.5% | Added |
| XTX Topco Ltd | 47,674 | $337.5K | 0.01% | +36,026+309.3% | Added |
| SEI Investments Co | 49,056 | $347.3K | 0.00% | 00.0% | Unchanged |
| State of Tennessee, Treasury Department | 61,153 | $392.6K | 0.00% | +16,311+36.4% | Added |
| Jane Street Group, LLC | 63,190 | $447.4K | 0.00% | −39,269−38.3% | Reduced |
| DAFNA Capital Management LLC | 64,492 | $456.6K | 0.11% | 00.0% | Unchanged |
| Nan Fung Group Holdings Ltd | 68,943 | $488.1K | 0.44% | 00.0% | Unchanged |
| State Street Corp | 70,178 | $496.9K | 0.00% | −4,227−5.7% | Reduced |
| Point72 Asset Management, L.P. | 76,779 | $543.6K | 0.00% | −354,121−82.2% | Reduced |
| Marex Group plc | 78,406 | $555.1K | 0.01% | +78,406 | New |
| Monimus Capital Management, LP | 93,840 | $664.4K | 0.44% | +8,616+10.1% | Added |
| Bank of America Corp | 96,401 | $682.5K | 0.00% | −495,134−83.7% | Reduced |
| Susquehanna International Group, LLP | 108,423 | $767.6K | 0.00% | +81,794+307.2% | Added |
| Walleye Capital LLC | 111,659 | $790.5K | 0.00% | +111,659 | New |
| Manufacturers Life Insurance Company, The | 127,863 | $869.5K | 0.00% | −12,629−9.0% | Reduced |
| Rangeley Capital, LLC | 132,000 | $934.6K | 0.81% | +2,000+1.5% | Added |
| Two Sigma Investments, LP | 132,032 | $934.8K | 0.00% | −52,505−28.5% | Reduced |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 134,689 | $953.6K | 0.03% | +134,689 | New |
| Two Sigma Advisers, LP | 146,100 | $1.03M | 0.00% | −10,600−6.8% | Reduced |
| TD Asset Management Inc | 147,992 | $1.05M | 0.00% | −30,100−16.9% | Reduced |
| Flax Pond Capital, LLC | 173,633 | $1.23M | 0.91% | +173,633 | New |
| Eversept Partners, LP | 178,915 | $1.27M | 0.07% | −15,525−8.0% | Reduced |
| Platinum Investment Management Ltd | 184,603 | $1.31M | 0.30% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 190,480 | $1.35M | 0.02% | −6,138−3.1% | Reduced |
| Palo Alto Investors LP | 221,071 | $1.57M | 0.22% | 00.0% | Unchanged |
| Citadel Advisors LLC | 271,383 | $1.92M | 0.00% | +82,356+43.6% | Added |
| Moore Capital Management, LP | 275,000 | $1.95M | 0.04% | +150,000+120.0% | Added |
| Jefferies Financial Group Inc. | 297,247 | $2.10M | 0.02% | −104,679−26.0% | Reduced |
| Millennium Management LLC | 326,626 | $2.31M | 0.00% | −728,120−69.0% | Reduced |
| BlackRock, Inc. | 332,889 | $2.36M | 0.00% | +50,471+17.9% | Added |
| Birchview Capital, LP | 462,700 | $3.28M | 1.92% | +308,700+200.5% | Added |
| Morgan Stanley | 465,222 | $3.29M | 0.00% | −357,483−43.5% | Reduced |
| Silvercrest Asset Management Group LLC | 476,976 | $3.38M | 0.02% | 00.0% | Unchanged |
| Schroder Investment Management Group | 584,770 | $3.98M | 0.00% | +584,770 | New |
| Renaissance Technologies LLC | 566,600 | $4.01M | 0.01% | +47,900+9.2% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 568,225 | $4.02M | 0.00% | +568,225 | New |
| Principal Financial Group Inc | 1,148,272 | $8.13M | 0.00% | −1300.0% | Reduced |
| Price T Rowe Associates Inc | 1,171,787 | $8.30M | 0.00% | −213,007−15.4% | Reduced |
| Candriam Luxembourg S.C.A. | 1,192,279 | $8.44M | 0.04% | +19,892+1.7% | Added |