Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 3 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/9/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 437
- 較 2025 年第 2 季 +78 家
- 持有股數
- 1.68 億
- 較 2025 年第 2 季 −22.1 萬 (−0.1%)
- 總市值
- $110.1 億
- 較 2025 年第 2 季 +$43.6 億 (+65.5%)
- 新進機構
- 115
- 另有 136 家加碼
- 清倉機構
- 37
- 另有 116 家減碼
另有 4 家機構在 2025 年第 2 季持有、還沒有申報 2025 年第 3 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 3 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 2 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Millennium Management LLC | 779,570 | $5,100 萬 | 0.04% | −1,869,957−70.6% | 減碼 |
| Voloridge Investment Management, LLC | 803,047 | $5,254 萬 | 0.18% | −51,587−6.0% | 減碼 |
| Northern Trust Corp | 844,943 | $5,528 萬 | 0.01% | +30,693+3.8% | 加碼 |
| Bank of America Corp | 855,295 | $5,595 萬 | 0.00% | −140,595−14.1% | 減碼 |
| Massachusetts Financial Services Co | 862,593 | $5,643 萬 | 0.02% | +343,409+66.1% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 878,155 | $5,745 萬 | 0.18% | +612,362+230.4% | 加碼 |
| Artisan Partners Limited Partnership | 890,072 | $5,823 萬 | 0.08% | +535,110+150.8% | 加碼 |
| Marshall Wace, LLP | 958,829 | $6,273 萬 | 0.07% | +945,729+7,219.3% | 加碼 |
| TD Asset Management Inc | 960,272 | $6,282 萬 | 0.05% | −144,418−13.1% | 減碼 |
| Polar Capital Holdings Plc | 1,033,622 | $6,762 萬 | 0.33% | +33,622+3.4% | 加碼 |
| UBS Group AG | 1,046,990 | $6,849 萬 | 0.01% | −482,333−31.5% | 減碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,059,721 | $6,932 萬 | 0.18% | −291,158−21.6% | 減碼 |
| Vestal Point Capital, LP | 1,075,000 | $7,033 萬 | 3.19% | +575,000+115.0% | 加碼 |
| Macquarie Group Ltd | 1,131,936 | $7,405 萬 | 0.09% | −302,137−21.1% | 減碼 |
| UBS Asset Management Americas Inc | 1,154,166 | $7,551 萬 | 0.02% | +363,094+45.9% | 加碼 |
| Morgan Stanley | 1,180,316 | $7,722 萬 | 0.00% | −181,893−13.4% | 減碼 |
| Royal Bank of Canada | 1,226,624 | $8,024 萬 | 0.01% | +426,712+53.3% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,315,000 | $8,603 萬 | 0.14% | −2,485,000−65.4% | 減碼 |
| American Century Companies Inc | 1,372,225 | $8,977 萬 | 0.05% | +899,476+190.3% | 加碼 |
| Pictet Asset Management Holding SA | 1,393,124 | $9,048 萬 | 0.09% | +784,484+128.9% | 加碼 |
| Charles Schwab Investment Management Inc | 1,519,951 | $9,944 萬 | 0.02% | +32,133+2.2% | 加碼 |
| Two Sigma Investments, LP | 1,575,943 | $1.03 億 | 0.16% | −212,424−11.9% | 減碼 |
| Deerfield Management Company, L.P. (Series C) | 1,979,669 | $1.30 億 | 1.98% | +1,979,669 | 新進 |
| Two Sigma Advisers, LP | 2,073,111 | $1.36 億 | 0.27% | −594,500−22.3% | 減碼 |
| Citadel Advisors LLC | 2,402,065 | $1.57 億 | 0.13% | +907,084+60.7% | 加碼 |
| Price T Rowe Associates Inc | 2,729,685 | $1.79 億 | 0.02% | −396,388−12.7% | 減碼 |
| Tweedy, Browne Co LLC | 2,901,216 | $1.90 億 | 16.48% | +9,268+0.3% | 加碼 |
| Geode Capital Management, LLC | 3,066,289 | $2.01 億 | 0.01% | +175,194+6.1% | 加碼 |
| Deep Track Capital, LP | 3,808,144 | $2.49 億 | 6.95% | −1,083,400−22.1% | 減碼 |
| State Street Corp | 4,388,651 | $2.87 億 | 0.01% | −141,747−3.1% | 減碼 |
| Bellevue Group AG | 6,244,451 | $4.09 億 | 8.49% | −1,608,747−20.5% | 減碼 |
| Wellington Management Group LLP | 6,588,811 | $4.31 億 | 0.08% | +243,035+3.8% | 加碼 |
| BlackRock, Inc. | 10,447,940 | $6.84 億 | 0.01% | −448,997−4.1% | 減碼 |
| Capital World Investors | 12,722,728 | $8.32 億 | 0.11% | +182,540+1.5% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 13,156,929 | $8.61 億 | 0.53% | −2,891,792−18.0% | 減碼 |
| Vanguard Group Inc | 16,481,730 | $10.8 億 | 0.02% | −233,116−1.4% | 減碼 |
| FMR LLC | 23,689,038 | $15.5 億 | 0.08% | +46,048+0.2% | 加碼 |
| BVF Inc | 0 | $0 | 0.00% | −1,913,385−100.0% | 清倉 |
| Woodline Partners LP | 0 | $0 | 0.00% | −732,813−100.0% | 清倉 |
| AXA S.A. | 0 | $0 | 0.00% | −566,883−100.0% | 清倉 |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −292,647−100.0% | 清倉 |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −98,267−100.0% | 清倉 |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −81,251−100.0% | 清倉 |
| Worldquant Millennium Advisors LLC | 0 | $0 | 0.00% | −74,438−100.0% | 清倉 |
| Walleye Capital LLC | 0 | $0 | 0.00% | −66,482−100.0% | 清倉 |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −45,950−100.0% | 清倉 |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −37,649−100.0% | 清倉 |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −31,219−100.0% | 清倉 |
| Oxford Asset Management LLP | 0 | $0 | 0.00% | −22,405−100.0% | 清倉 |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −17,149−100.0% | 清倉 |
| Corton Capital Inc. | 0 | $0 | 0.00% | −14,424−100.0% | 清倉 |
| Vestmark Advisory Solutions, Inc. | 0 | $0 | 0.00% | −14,341−100.0% | 清倉 |
| Paloma Partners Management Co | 0 | $0 | 0.00% | −12,557−100.0% | 清倉 |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −10,988−100.0% | 清倉 |
| Harbor Advisors LLC | 0 | $0 | 0.00% | −10,500−100.0% | 清倉 |
| Colony Group, LLC | 0 | $0 | 0.00% | −10,056−100.0% | 清倉 |
| Semanteon Capital Management, LP | 0 | $0 | 0.00% | −9,536−100.0% | 清倉 |
| Jump Financial, LLC | 0 | $0 | 0.00% | −9,018−100.0% | 清倉 |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −6,813−100.0% | 清倉 |
| Teza Capital Management LLC | 0 | $0 | 0.00% | −6,604−100.0% | 清倉 |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −5,682−100.0% | 清倉 |
| Castle Rock Wealth Management, LLC | 0 | $0 | 0.00% | −5,122−100.0% | 清倉 |
| Callan Family Office, LLC | 0 | $0 | 0.00% | −5,400−100.0% | 清倉 |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −5,067−100.0% | 清倉 |
| Allianz SE | 0 | $0 | 0.00% | −2,100−100.0% | 清倉 |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −268−100.0% | 清倉 |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −215−100.0% | 清倉 |
| Riggs Asset Managment Co. Inc. | 0 | $0 | 0.00% | −187−100.0% | 清倉 |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −156−100.0% | 清倉 |
| Geneos Wealth Management Inc. | 0 | $0 | 0.00% | −139−100.0% | 清倉 |
| MPWM Advisory Solutions, LLC | 0 | $0 | 0.00% | −110−100.0% | 清倉 |
| Kestra Investment Management, LLC | 0 | $0 | 0.00% | −137−100.0% | 清倉 |
| Asset Dedication, LLC | 0 | $0 | 0.00% | −59−100.0% | 清倉 |
| WealthTrak Capital Management LLC | 0 | $0 | 0.00% | −5−100.0% | 清倉 |
| Norges Bank | – | – | – | – | 本季未申報 |
| E Fund Management Co., Ltd. | – | – | – | – | 本季未申報 |
| Semmax Financial Advisors Inc. | – | – | – | – | 本季未申報 |
| Parkworth Wealth Management, Inc. | – | – | – | – | 本季未申報 |