Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2021 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2021/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 341
- 較 2021 年第 3 季 +20 家
- 持有股數
- 1.23 億
- 較 2021 年第 3 季 +170.8 萬 (+1.4%)
- 總市值
- $37.5 億
- 較 2021 年第 3 季 −$3.26 億 (−8.0%)
- 新進機構
- 59
- 另有 106 家加碼
- 清倉機構
- 39
- 另有 119 家減碼
另有 5 家機構在 2021 年第 3 季持有、還沒有申報 2021 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2021 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2021 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Eaton Vance Management | 27,692 | $84.3 萬 | 0.00% | +818+3.0% | 加碼 |
| First Foundation Advisors | 27,972 | $85.1 萬 | 0.03% | −7,774−21.7% | 減碼 |
| Capital Fund Management S.A. | 28,108 | $85.5 萬 | 0.02% | +28,108 | 新進 |
| Ensign Peak Advisors, Inc | 28,330 | $86.2 萬 | 0.00% | +28,330 | 新進 |
| Commonwealth Equity Services, LLC | 28,766 | $87.5 萬 | 0.00% | −9,352−24.5% | 減碼 |
| Koss-Olinger Consulting, LLC | 29,161 | $88.7 萬 | 0.14% | +17,729+155.1% | 加碼 |
| Amalgamated Bank | 29,324 | $89.2 萬 | 0.01% | +3,923+15.4% | 加碼 |
| Truist Financial Corp | 30,937 | $94.1 萬 | 0.00% | −40−0.1% | 減碼 |
| Principal Financial Group Inc | 31,755 | $96.6 萬 | 0.00% | −10,930−25.6% | 減碼 |
| Employees Retirement System of Texas | 32,409 | $98.6 萬 | 0.01% | 00.0% | 不變 |
| Macquarie Group Ltd | 32,549 | $99.1 萬 | 0.00% | +121+0.4% | 加碼 |
| Trexquant Investment LP | 33,903 | $103.2 萬 | 0.06% | +20,606+155.0% | 加碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 34,069 | $103.7 萬 | 0.00% | +34,069 | 新進 |
| Arizona State Retirement System | 34,190 | $104.0 萬 | 0.01% | −367−1.1% | 減碼 |
| Engineers Gate Manager LP | 34,380 | $104.6 萬 | 0.05% | +17,708+106.2% | 加碼 |
| Group One Trading, L.P. | 36,268 | $110.4 萬 | 0.02% | +4,735+15.0% | 加碼 |
| Janney Montgomery Scott LLC | 36,424 | $110.8 萬 | 0.00% | +2,271+6.6% | 加碼 |
| Algert Global LLC | 38,430 | $116.9 萬 | 0.15% | +14,956+63.7% | 加碼 |
| Capital Counsel LLC | 40,580 | $123.5 萬 | 0.05% | 00.0% | 不變 |
| Bard Financial Services, Inc. | 41,520 | $126.3 萬 | 0.10% | +31,795+326.9% | 加碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $127.8 萬 | 0.16% | 00.0% | 不變 |
| Jefferies Group LLC | 44,000 | $133.9 萬 | 0.02% | −137−0.3% | 減碼 |
| Assenagon Asset Management S.A. | 48,401 | $147.3 萬 | 0.01% | +42,379+703.7% | 加碼 |
| Pura Vida Investments, LLC | 48,544 | $147.7 萬 | 0.15% | +48,544 | 新進 |
| Raymond James Financial Services Advisors, Inc. | 48,981 | $149.0 萬 | 0.00% | +2,825+6.1% | 加碼 |
| Alpha DNA Investment Management LLC | 50,614 | $153.9 萬 | 0.98% | +50,614 | 新進 |
| Treasurer of the State of North Carolina | 50,846 | $154.7 萬 | 0.01% | +330+0.7% | 加碼 |
| Erste Asset Management GmbH | 51,300 | $157.1 萬 | 0.03% | 00.0% | 不變 |
| Jane Street Group, LLC | 52,550 | $159.9 萬 | 0.00% | −11,926−18.5% | 減碼 |
| AlphaCrest Capital Management LLC | 52,907 | $161.0 萬 | 0.06% | +823+1.6% | 加碼 |
| Point72 Asset Management, L.P. | 53,981 | $164.3 萬 | 0.01% | −165,319−75.4% | 減碼 |
| Canada Pension Plan Investment Board | 57,924 | $176.3 萬 | 0.00% | +57,924 | 新進 |
| Squarepoint Ops LLC | 61,340 | $186.7 萬 | 0.01% | −108,525−63.9% | 減碼 |
| Voya Investment Management LLC | 65,508 | $199.3 萬 | 0.00% | +22,808+53.4% | 加碼 |
| PDT Partners, LLC | 67,697 | $206.0 萬 | 0.16% | +67,697 | 新進 |
| National Bank of Canada | 70,000 | $213.0 萬 | 0.01% | +70,000 | 新進 |
| Guggenheim Capital LLC | 72,978 | $222.1 萬 | 0.01% | +10,341+16.5% | 加碼 |
| Rhenman & Partners Asset Management AB | 75,000 | $229.1 萬 | 0.15% | 00.0% | 不變 |
| PFS Investments Inc. | 76,179 | $231.8 萬 | 0.04% | −663−0.9% | 減碼 |
| Parkman Healthcare Partners LLC | 80,238 | $244.2 萬 | 0.55% | −56,142−41.2% | 減碼 |
| Allianz Asset Management GmbH | 81,830 | $249.1 萬 | 0.00% | +62,120+315.2% | 加碼 |
| Davenport & Co LLC | 84,663 | $257.6 萬 | 0.02% | −37,640−30.8% | 減碼 |
| Public Employees Retirement System of Ohio | 84,661 | $257.6 萬 | 0.01% | −2,783−3.2% | 減碼 |
| Gateway Investment Advisers LLC | 85,103 | $259.0 萬 | 0.02% | +46,971+123.2% | 加碼 |
| AXA S.A. | 87,900 | $267.5 萬 | 0.01% | +30,700+53.7% | 加碼 |
| LPL Financial LLC | 88,666 | $269.8 萬 | 0.00% | +5,051+6.0% | 加碼 |
| Envestnet Asset Management Inc | 91,292 | $277.8 萬 | 0.00% | −11,130−10.9% | 減碼 |
| State of New Jersey Common Pension Fund D | 95,234 | $289.8 萬 | 0.01% | +8,018+9.2% | 加碼 |
| Allspring Global Investments Holdings, LLC | 98,574 | $299.9 萬 | 0.00% | +98,574 | 新進 |
| Alliancebernstein L.P. | 103,214 | $314.1 萬 | 0.00% | +34,763+50.8% | 加碼 |
| Wolverine Trading, LLC | 108,529 | $331.4 萬 | 0.04% | +1,651+1.5% | 加碼 |
| DekaBank Deutsche Girozentrale | 109,476 | $334.7 萬 | 0.01% | +1,900+1.8% | 加碼 |
| Connor, Clark & Lunn Investment Management Ltd. | 112,525 | $342.4 萬 | 0.02% | +76,989+216.7% | 加碼 |
| Private Advisor Group, LLC | 115,742 | $352.2 萬 | 0.03% | +71,637+162.4% | 加碼 |
| Jump Financial, LLC | 120,500 | $366.7 萬 | 0.23% | +120,500 | 新進 |
| Invesco Ltd. | 132,242 | $402.4 萬 | 0.00% | −9,113−6.4% | 減碼 |
| Peregrine Capital Management LLC | 139,721 | $425.2 萬 | 0.09% | +3,934+2.9% | 加碼 |
| Rhumbline Advisers | 139,749 | $425.3 萬 | 0.01% | +1,386+1.0% | 加碼 |
| BLB&B Advisors, LLC | 150,935 | $459.3 萬 | 0.30% | −5,265−3.4% | 減碼 |
| New York State Common Retirement Fund | 153,800 | $468.0 萬 | 0.00% | −87,359−36.2% | 減碼 |
| Sonora Investment Management Group, LLC | 156,790 | $477.1 萬 | 0.55% | +156,790 | 新進 |
| Legal & General Group Plc | 158,344 | $481.8 萬 | 0.00% | −9,077−5.4% | 減碼 |
| D. E. Shaw & Co., Inc. | 160,659 | $488.9 萬 | 0.01% | +34,553+27.4% | 加碼 |
| Alps Advisors Inc | 163,424 | $497.3 萬 | 0.06% | +163,424 | 新進 |
| Tocqueville Asset Management L.P. | 170,405 | $518.5 萬 | 0.07% | +1,875+1.1% | 加碼 |
| State Board of Administration of Florida Retirement System | 173,260 | $527.2 萬 | 0.01% | +11,322+7.0% | 加碼 |
| Tekla Capital Management LLC | 175,680 | $534.6 萬 | 0.17% | −146,841−45.5% | 減碼 |
| Majedie Asset Management Ltd | 175,508 | $534.7 萬 | 0.41% | 00.0% | 不變 |
| Credit Suisse AG | 176,767 | $537.9 萬 | 0.00% | −5,895−3.2% | 減碼 |
| Tudor Investment Corp Et Al | 178,386 | $542.8 萬 | 0.10% | −23,227−11.5% | 減碼 |
| Pictet Asset Management SA | 183,087 | $557.1 萬 | 0.01% | +47,391+34.9% | 加碼 |
| UBS Asset Management Americas Inc | 183,752 | $559.2 萬 | 0.00% | +3,087+1.7% | 加碼 |
| California State Teachers Retirement System | 184,004 | $559.9 萬 | 0.01% | −41,987−18.6% | 減碼 |
| Citigroup Inc | 186,047 | $566.1 萬 | 0.01% | +64,983+53.7% | 加碼 |
| Rafferty Asset Management, LLC | 189,639 | $577.1 萬 | 0.03% | +92,902+96.0% | 加碼 |
| Balyasny Asset Management LLC | 193,120 | $587.7 萬 | 0.03% | +51,105+36.0% | 加碼 |
| UBS Group AG | 193,589 | $589.1 萬 | 0.00% | +60,777+45.8% | 加碼 |
| Russell Investments Group, Ltd. | 194,145 | $590.6 萬 | 0.01% | −37,720−16.3% | 減碼 |
| MUFG Securities EMEA plc | 200,000 | $608.6 萬 | 0.13% | +200,000 | 新進 |
| Susquehanna International Group, LLP | 204,255 | $621.5 萬 | 0.01% | +30,089+17.3% | 加碼 |
| Sector Gamma AS | 209,537 | $637.6 萬 | 1.50% | −54,333−20.6% | 減碼 |
| Morningstar Investment Services LLC | 219,432 | $667.9 萬 | 0.07% | +5,291+2.5% | 加碼 |
| Parametric Portfolio Associates LLC | 225,106 | $685.0 萬 | 0.00% | −6,400−2.8% | 減碼 |
| Renaissance Technologies LLC | 230,814 | $702.4 萬 | 0.01% | +133,100+136.2% | 加碼 |
| Bank of Montreal | 229,407 | $716.7 萬 | 0.00% | −20,297−8.1% | 減碼 |
| Raymond James & Associates | 257,985 | $785.0 萬 | 0.01% | −43,464−14.4% | 減碼 |
| Voloridge Investment Management, LLC | 266,845 | $812.0 萬 | 0.04% | +266,845 | 新進 |
| Swiss National Bank | 279,300 | $849.9 萬 | 0.01% | −600−0.2% | 減碼 |
| Sicart Associates LLC | 282,531 | $862.8 萬 | 2.25% | −8,723−3.0% | 減碼 |
| California Public Employees Retirement System | 284,424 | $865.5 萬 | 0.01% | −3,704−1.3% | 減碼 |
| Cubist Systematic Strategies, LLC | 297,182 | $904.3 萬 | 0.09% | +210,428+242.6% | 加碼 |
| Natixis | 300,797 | $915.3 萬 | 0.03% | +300,797 | 新進 |
| Dowling & Yahnke LLC | 302,421 | $920.3 萬 | 0.44% | −1000.0% | 減碼 |
| Hudson Bay Capital Management LP | 305,000 | $928.1 萬 | 0.10% | +40,000+15.1% | 加碼 |
| BNP Paribas Arbitrage, SA | 306,253 | $931.9 萬 | 0.02% | +280,521+1,090.2% | 加碼 |
| Baillie Gifford & Co | 315,820 | $961.1 萬 | 0.01% | +13,817+4.6% | 加碼 |
| Sio Capital Management, LLC | 322,566 | $981.6 萬 | 2.99% | +322,566 | 新進 |
| Barclays PLC | 329,938 | $1,004 萬 | 0.01% | −353−0.1% | 減碼 |
| Nuveen Asset Management, LLC | 351,476 | $1,070 萬 | 0.00% | −277,000−44.1% | 減碼 |
| International Biotechnology Trust PLC | 355,088 | $1,081 萬 | 2.41% | +310,307+692.9% | 加碼 |