Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Huntington National Bank | 29,447 | $11.5M | 0.07% | −3,965−11.9% | Reduced |
| Apollon Wealth Management, LLC | 29,366 | $11.5M | 0.20% | −391−1.3% | Reduced |
| Oregon Public Employees Retirement Fund | 29,285 | $11.5M | 0.15% | +7,101+32.0% | Added |
| Massmutual Trust Co FSB | 28,495 | $11.2M | 0.28% | +1,704+6.4% | Added |
| CCM Investment Advisers LLC | 28,309 | $11.1M | 1.09% | −1,306−4.4% | Reduced |
| OP Asset Management Ltd | 28,288 | $11.1M | 0.15% | +511+1.8% | Added |
| Y-Intercept (Hong Kong) Ltd | 27,770 | $10.9M | 0.26% | +27,770 | New |
| Mutual of America Capital Management LLC | 27,746 | $10.9M | 0.11% | −1,660−5.6% | Reduced |
| Shelter Mutual Insurance Co | 27,600 | $10.8M | 2.42% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 27,361 | $10.7M | 0.06% | −14,190−34.2% | Reduced |
| Avanza Fonder AB | 27,053 | $10.6M | 0.27% | +1,628+6.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 26,784 | $10.5M | 0.17% | +26,784 | New |
| Profund Advisors LLC | 26,395 | $10.3M | 0.34% | −958−3.5% | Reduced |
| Sig Brokerage, LP | 26,390 | $10.3M | 2.60% | −6,176−19.0% | Reduced |
| Bender Robert & Associates | 26,330 | $10.3M | 2.23% | −382−1.4% | Reduced |
| Fagan Associates, Inc. | 26,306 | $10.3M | 1.42% | +111+0.4% | Added |
| ASR Vermogensbeheer N.V. | 26,294 | $10.3M | 0.12% | −125−0.5% | Reduced |
| Capital Group Investment Management Pte. Ltd. | 26,286 | $10.3M | 1.73% | −1,213−4.4% | Reduced |
| Bogart Wealth, LLC | 26,149 | $10.2M | 0.42% | +742+2.9% | Added |
| Fisher Asset Management, LLC | 25,959 | $10.2M | 0.00% | +204+0.8% | Added |
| Meritage Portfolio Management | 25,940 | $10.2M | 0.68% | −7,003−21.3% | Reduced |
| Advisors Asset Management, Inc. | 25,926 | $10.2M | 0.17% | +841+3.4% | Added |
| Atria Investments LLC | 25,919 | $10.2M | 0.12% | +2,418+10.3% | Added |
| LVM Capital Management Ltd | 25,840 | $10.1M | 0.97% | −4,230−14.1% | Reduced |
| Generate Investment Management Ltd | 25,734 | $10.1M | 0.51% | +25,734 | New |
| ARK Investment Management LLCSuperinvestorARK Invest | 25,665 | $10.1M | 0.06% | +1,602+6.7% | Added |
| Yousif Capital Management, LLC | 25,662 | $10.1M | 0.11% | −455−1.7% | Reduced |
| Oppenheimer Asset Management Inc. | 25,460 | $9.97M | 0.11% | +3,972+18.5% | Added |
| Pinnacle Associates Ltd | 25,367 | $9.93M | 0.13% | +259+1.0% | Added |
| CAPROCK Group, Inc. | 25,216 | $9.86M | 0.24% | +25,216 | New |
| Biondo Investment Advisors, LLC | 25,075 | $9.82M | 1.23% | +146+0.6% | Added |
| Jacobs Levy Equity Management, Inc | 24,949 | $9.77M | 0.04% | −26,007−51.0% | Reduced |
| Capital Group Private Client Services, Inc. | 24,874 | $9.74M | 0.16% | −79,663−76.2% | Reduced |
| Americana Partners, LLC | 24,468 | $9.58M | 0.29% | +12,134+98.4% | Added |
| PEAK6 LLC | 24,416 | $9.56M | 0.24% | −6,040−19.8% | Reduced |
| Allianz SE | 23,921 | $9.37M | 0.20% | −14−0.1% | Reduced |
| Generali Asset Management SPA SGR | 23,569 | $9.23M | 0.20% | +6,942+41.8% | Added |
| Cary Street Partners Financial LLC | 22,923 | $8.98M | 0.23% | −586−2.5% | Reduced |
| GW Henssler & Associates Ltd | 22,791 | $8.93M | 0.45% | +28+0.1% | Added |
| Somerville Kurt F | 22,643 | $8.87M | 1.47% | −543−2.3% | Reduced |
| Public Sector Pension Investment Board | 22,418 | $8.78M | 0.03% | +2,744+13.9% | Added |
| Fifth Third Bancorp | 22,223 | $8.70M | 0.03% | −2,001−8.3% | Reduced |
| Kennedy Capital Management, Inc. | 22,180 | $8.69M | 0.19% | +2,770+14.3% | Added |
| Norinchukin Bank, The | 22,026 | $8.63M | 0.12% | +90+0.4% | Added |
| EULAV Asset Management | 22,000 | $8.62M | 0.20% | −700−3.1% | Reduced |
| Fiduciary Trust Co | 21,921 | $8.59M | 0.10% | +4,402+25.1% | Added |
| Gotham Asset Management, LLC | 21,888 | $8.57M | 0.04% | +532+2.5% | Added |
| Modera Wealth Management, LLC | 21,853 | $8.56M | 0.10% | −1,252−5.4% | Reduced |
| Telos Capital Management, Inc. | 21,188 | $8.30M | 0.80% | +1,946+10.1% | Added |
| Camden National Bank | 20,892 | $8.18M | 1.14% | +430+2.1% | Added |
| Wiley Bros.-Aintree Capital, LLC | 27,949 | $8.16M | 0.05% | +2,809+11.2% | Added |
| Wolverine Trading, LLC | 20,449 | $8.08M | 0.16% | +2,854+16.2% | Added |
| Prosight Management, LP | 20,500 | $8.03M | 1.93% | +20,500 | New |
| UniSuper Management Pty Ltd | 20,495 | $8.03M | 0.05% | +3,847+23.1% | Added |
| AIMZ Investment Advisors, LLC | 20,361 | $7.97M | 2.50% | −365−1.8% | Reduced |
| Azimuth Capital Investment Management LLC | 20,348 | $7.97M | 0.29% | −684−3.3% | Reduced |
| Warren Averett Asset Management, LLC | 20,248 | $7.93M | 0.08% | +103+0.5% | Added |
| Heirloom Wealth Management | 19,966 | $7.82M | 1.89% | +333+1.7% | Added |
| Grandfield & Dodd, LLC | 19,820 | $7.76M | 0.44% | +1,533+8.4% | Added |
| HealthInvest Partners AB | 17,766 | $7.39M | 2.74% | −6,562−27.0% | Reduced |
| Mercer Global Advisors Inc | 18,784 | $7.36M | 0.01% | +261+1.4% | Added |
| Bridger Management, LLC | 18,778 | $7.35M | 3.96% | 00.0% | Unchanged |
| Mizuho Securities USA LLC | 18,674 | $7.30M | 0.15% | +924+5.2% | Added |
| Envestnet Portfolio Solutions, Inc. | 18,221 | $7.14M | 0.03% | +927+5.4% | Added |
| Blair William & Co | 17,990 | $7.05M | 0.02% | −8,087−31.0% | Reduced |
| Motley Fool Asset Management LLC | 17,698 | $6.93M | 0.29% | +1,904+12.1% | Added |
| Sterling Capital Management LLC | 17,478 | $6.85M | 0.10% | −2,966−14.5% | Reduced |
| Broderick Brian C | 17,251 | $6.76M | 1.28% | −420−2.4% | Reduced |
| Silvercrest Asset Management Group LLC | 16,959 | $6.64M | 0.04% | +60.0% | Added |
| Prudential PLC | 16,568 | $6.49M | 0.05% | −2,957−15.1% | Reduced |
| Fulcrum Capital LLC | 16,256 | $6.37M | 1.31% | +458+2.9% | Added |
| Torray LLC | 16,255 | $6.37M | 0.86% | −624−3.7% | Reduced |
| Madison Asset Management, LLC | 16,201 | $6.34M | 0.07% | +2,009+14.2% | Added |
| Kentucky Retirement Systems | 16,147 | $6.32M | 0.17% | −427−2.6% | Reduced |
| LMR Partners LLP | 16,101 | $6.31M | 0.08% | +16,101 | New |
| Jefferies Financial Group Inc. | 16,000 | $6.27M | 0.06% | −18,615−53.8% | Reduced |
| Nia Impact Advisors, LLC | 15,933 | $6.24M | 2.03% | +46+0.3% | Added |
| QRG Capital Management, Inc. | 15,833 | $6.20M | 0.08% | −3,203−16.8% | Reduced |
| Trifecta Capital Advisors, LLC | 15,833 | $6.20M | 0.94% | +493+3.2% | Added |
| Anderson Hoagland & Co | 15,767 | $6.17M | 0.55% | −3,880−19.7% | Reduced |
| Aptus Capital Advisors, LLC | 15,755 | $6.17M | 0.06% | +1,868+13.5% | Added |
| Baldwin Investment Management, LLC | 15,748 | $6.17M | 0.71% | +1,207+8.3% | Added |
| Janney Capital Management LLC | 15,707 | $6.15M | 0.38% | −524−3.2% | Reduced |
| Puzo Michael J | 15,501 | $6.07M | 1.66% | +161+1.0% | Added |
| Northwest & Ethical Investments L.P. | 15,315 | $6.00M | 0.14% | +226+1.5% | Added |
| Investment Management Corp of Ontario | 15,235 | $5.97M | 0.09% | +3,560+30.5% | Added |
| Prevail Innovative Wealth Advisors, LLC | 15,200 | $5.95M | 1.16% | +15,200 | New |
| Park Avenue Securities LLC | 15,043 | $5.89M | 0.05% | −319−2.1% | Reduced |
| Hartford Investment Management Co | 15,022 | $5.88M | 0.18% | −476−3.1% | Reduced |
| Gabelli Funds LLC | 15,002 | $5.88M | 0.04% | −1,327−8.1% | Reduced |
| Engineers Gate Manager LP | 14,843 | $5.81M | 0.07% | +14,843 | New |
| Ameritas Investment Partners, Inc. | 14,831 | $5.81M | 0.18% | −78−0.5% | Reduced |
| Atlantic Union Bankshares Corp | 14,688 | $5.75M | 0.11% | +5,741+64.2% | Added |
| Toroso Investments, LLC | 14,632 | $5.73M | 0.02% | +367+2.6% | Added |
| Princeton Capital Management LLC | 14,438 | $5.65M | 1.52% | −37−0.3% | Reduced |
| Kestra Advisory Services, LLC | 14,391 | $5.64M | 0.03% | +33+0.2% | Added |
| Knuff & Co LLC | 14,184 | $5.56M | 1.61% | +188+1.3% | Added |
| First Horizon Corp | 14,121 | $5.53M | 0.26% | +14,121 | New |
| Cambridge Investment Research Advisors, Inc. | 14,117 | $5.53M | 0.02% | −3,212−18.5% | Reduced |
| Tower Research Capital LLC (TRC) | 14,022 | $5.49M | 0.15% | −9,456−40.3% | Reduced |