Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,034
- +113 vs. Q3 2021
- Shares held
- 230.3M
- −775.4K (−0.3%) vs. Q3 2021
- Total value
- $50.4B
- +$8.64B (+20.7%) vs. Q3 2021
- New holders
- 201
- 334 more added
- Sold out
- 88
- 369 more reduced
15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock Inc. | 23,944,931 | $5.26B | 0.13% | +397,036+1.7% | Added |
| Vanguard Group Inc | 20,155,842 | $4.43B | 0.10% | −286,849−1.4% | Reduced |
| State Street Corp | 12,356,915 | $2.71B | 0.13% | +33,499+0.3% | Added |
| Capital World Investors | 11,520,855 | $2.53B | 0.40% | +478,553+4.3% | Added |
| Alliancebernstein L.P. | 10,443,771 | $2.29B | 0.81% | +1,374,923+15.2% | Added |
| FMR LLC | 9,093,853 | $2.00B | 0.15% | +4,216,754+86.5% | Added |
| Loomis Sayles & Co L P | 6,635,253 | $1.46B | 1.76% | −370,739−5.3% | Reduced |
| Wellington Management Group LLP | 6,518,455 | $1.43B | 0.23% | +427,366+7.0% | Added |
| Price T Rowe Associates Inc | 5,421,291 | $1.19B | 0.11% | −276,956−4.9% | Reduced |
| Clearbridge Investments, LLC | 5,196,730 | $1.14B | 0.78% | +84,326+1.6% | Added |
| JPMorgan Chase & Co | 4,464,331 | $980.4M | 0.12% | +252,599+6.0% | Added |
| Ameriprise Financial Inc | 4,423,196 | $969.2M | 0.27% | +1,034,106+30.5% | Added |
| Geode Capital Management, LLC | 4,356,220 | $954.3M | 0.11% | +53,868+1.3% | Added |
| UBS Asset Management Americas Inc | 3,514,231 | $771.7M | 0.30% | +755,378+27.4% | Added |
| Massachusetts Financial Services Co | 3,194,678 | $701.5M | 0.19% | +45,438+1.4% | Added |
| Bank of America Corp | 3,098,017 | $680.3M | 0.07% | +67,661+2.2% | Added |
| Northern Trust Corp | 2,908,352 | $638.7M | 0.10% | −86,138−2.9% | Reduced |
| Norges Bank | 2,679,899 | $588.5M | 0.12% | +153,719+6.1% | Added |
| Deutsche Bank AG | 2,559,313 | $562.0M | 0.25% | −127,278−4.7% | Reduced |
| Bank of New York Mellon Corp | 2,062,806 | $453.0M | 0.08% | −25,982−1.2% | Reduced |
| Capital International Investors | 2,027,232 | $445.2M | 0.09% | −1,922,320−48.7% | Reduced |
| Janus Henderson Group PLC | 1,990,740 | $437.2M | 0.18% | −144,038−6.7% | Reduced |
| California Public Employees Retirement System | 1,938,819 | $425.8M | 0.28% | −67,499−3.4% | Reduced |
| Legal & General Group Plc | 1,898,644 | $416.9M | 0.13% | −169,690−8.2% | Reduced |
| Harding Loevner LP | 1,881,871 | $413.3M | 1.58% | −29,232−1.5% | Reduced |
| Bellevue Group AG | 1,791,761 | $393.5M | 4.06% | +30,145+1.7% | Added |
| Canada Pension Plan Investment Board | 1,708,354 | $375.2M | 0.40% | +15,560+0.9% | Added |
| Renaissance Technologies LLC | 1,626,868 | $357.3M | 0.44% | −264,618−14.0% | Reduced |
| Nuveen Asset Management, LLC | 1,343,834 | $295.1M | 0.09% | −21,391−1.6% | Reduced |
| Charles Schwab Investment Management Inc | 1,261,688 | $277.1M | 0.08% | +19,703+1.6% | Added |
| Caisse de Depot Et Placement du Quebec | 1,228,508 | $269.8M | 0.58% | −266,708−17.8% | Reduced |
| Pictet Asset Management SA | 1,212,319 | $266.2M | 0.27% | +147,497+13.9% | Added |
| Goldman Sachs Group Inc | 1,187,377 | $260.7M | 0.06% | −206,385−14.8% | Reduced |
| Invesco Ltd. | 1,122,158 | $246.4M | 0.06% | −92,335−7.6% | Reduced |
| APG Asset Management N.V. | 1,206,589 | $233.0M | 0.40% | −22,100−1.8% | Reduced |
| Franklin Resources Inc | 1,059,301 | $232.6M | 0.08% | +192,377+22.2% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,039,746 | $228.3M | 0.14% | −52,295−4.8% | Reduced |
| Impax Asset Management Group plc | 1,032,855 | $226.8M | 0.83% | −41,881−3.9% | Reduced |
| D. E. Shaw & Co., Inc. | 1,021,323 | $224.3M | 0.27% | −693,311−40.4% | Reduced |
| Swiss National Bank | 986,075 | $216.5M | 0.13% | −37,600−3.7% | Reduced |
| Morgan Stanley | 969,807 | $213.0M | 0.03% | −72,706−7.0% | Reduced |
| Man Group plc | 963,525 | $211.6M | 0.68% | −247,918−20.5% | Reduced |
| Dimensional Fund Advisors LP | 934,033 | $205.1M | 0.06% | +229,487+32.6% | Added |
| ARK Investment Management LLCSuperinvestorARK Invest | 928,791 | $204.0M | 0.62% | −780,960−45.7% | Reduced |
| Vaughan Nelson Investment Management, L.P. | 923,747 | $202.9M | 2.08% | +923,747 | New |
| Lazard Asset Management LLC | 915,720 | $201.1M | 0.21% | +749,784+451.9% | Added |
| Parametric Portfolio Associates LLC | 877,007 | $192.6M | 0.10% | +142,022+19.3% | Added |
| Manning & Napier Group, LLC | 873,972 | $191.9M | 1.60% | +1,044+0.1% | Added |
| Amundi | 823,754 | $186.6M | 0.12% | +133,856+19.4% | Added |
| Wells Fargo & Company | 845,804 | $185.7M | 0.05% | −285,787−25.3% | Reduced |
| Epoch Investment Partners, Inc. | 819,848 | $180.0M | 0.91% | +503,347+159.0% | Added |
| Jennison Associates LLC | 783,389 | $172.0M | 0.11% | −45,970−5.5% | Reduced |
| Royal Bank of Canada | 703,699 | $154.5M | 0.04% | −76,891−9.9% | Reduced |
| Swedbank AB | 664,156 | $147.7M | 0.25% | +8,960+1.4% | Added |
| Natixis Advisors, L.P. | 667,802 | $146.7M | 0.56% | +51,094+8.3% | Added |
| Allianz Asset Management GmbH | 660,827 | $145.2M | 0.11% | −8,617−1.3% | Reduced |
| Prudential Financial Inc | 660,505 | $144.8M | 0.18% | +49,727+8.1% | Added |
| Citigroup Inc | 659,371 | $144.8M | 0.13% | +79,762+13.8% | Added |
| OrbiMed Advisors LLC | 658,100 | $144.5M | 1.88% | −219,300−25.0% | Reduced |
| Candriam Luxembourg S.C.A. | 644,632 | $141.6M | 0.90% | +51,803+8.7% | Added |
| Credit Suisse AG | 629,495 | $138.2M | 0.11% | +22,364+3.7% | Added |
| American Century Companies Inc | 624,453 | $137.1M | 0.09% | −145,053−18.9% | Reduced |
| Parnassus Investments | 619,438 | $136.0M | 0.26% | 00.0% | Unchanged |
| AQR Capital Management LLC | 598,483 | $131.4M | 0.24% | −40,834−6.4% | Reduced |
| KBC Group NV | 585,254 | $128.5M | 0.42% | +305,091+108.9% | Added |
| Barclays PLC | 580,598 | $127.5M | 0.08% | +11,895+2.1% | Added |
| First Trust Advisors LP | 521,427 | $114.5M | 0.11% | +30,756+6.3% | Added |
| ProShare Advisors LLC | 517,189 | $113.6M | 0.22% | +144,037+38.6% | Added |
| New York State Common Retirement Fund | 489,848 | $107.6M | 0.11% | −13,535−2.7% | Reduced |
| Armistice Capital, LLC | 488,000 | $107.2M | 2.61% | −148,000−23.3% | Reduced |
| DnB Asset Management AS | 487,895 | $107.1M | 0.63% | −22,007−4.3% | Reduced |
| Clal Insurance Enterprises Holdings Ltd | 481,000 | $105.6M | 1.14% | +323,500+205.4% | Added |
| Manufacturers Life Insurance Company, The | 476,920 | $105.3M | 0.06% | −116,047−19.6% | Reduced |
| Public Employees Retirement Association of Colorado | 462,461 | $101.6M | 0.42% | −6,646−1.4% | Reduced |
| Artisan Partners Limited Partnership | 462,314 | $101.5M | 0.12% | −2,717−0.6% | Reduced |
| California State Teachers Retirement System | 461,347 | $101.3M | 0.12% | +12,765+2.8% | Added |
| Raymond James & Associates | 457,083 | $100.4M | 0.08% | +17,602+4.0% | Added |
| Camber Capital Management LP | 450,000 | $98.8M | 3.81% | +450,000 | New |
| Millennium Management LLC | 446,853 | $98.1M | 0.11% | −248,855−35.8% | Reduced |
| Retirement Systems of Alabama | 433,295 | $95.2M | 0.33% | −1,772−0.4% | Reduced |
| AXA S.A. | 406,199 | $89.2M | 0.23% | −15,690−3.7% | Reduced |
| Great West Life Assurance Co | 405,622 | $88.8M | 0.18% | +16,035+4.1% | Added |
| Rhumbline Advisers | 392,266 | $86.1M | 0.11% | +6,992+1.8% | Added |
| Fred Alger Management, LLC | 389,546 | $85.5M | 0.21% | +386,859+14,397.4% | Added |
| Eaton Vance Management | 388,956 | $85.4M | 0.10% | −50,755−11.5% | Reduced |
| HSBC Holdings PLC | 379,213 | $83.6M | 0.09% | −21,846−5.4% | Reduced |
| National Pension Service | 379,890 | $83.4M | 0.15% | +8,944+2.4% | Added |
| Polar Capital Holdings Plc | 375,000 | $82.3M | 0.43% | +75,000+25.0% | Added |
| UBS Group AG | 356,471 | $78.3M | 0.03% | −146,377−29.1% | Reduced |
| Bank of Montreal | 341,874 | $76.1M | 0.04% | −711,485−67.5% | Reduced |
| DekaBank Deutsche Girozentrale | 338,255 | $76.0M | 0.18% | −6,454−1.9% | Reduced |
| Susquehanna International Group, LLP | 336,325 | $73.9M | 0.11% | −213,904−38.9% | Reduced |
| Allspring Global Investments Holdings, LLC | 335,605 | $73.7M | 0.08% | +335,605 | New |
| TD Asset Management Inc | 329,779 | $72.4M | 0.06% | +9,855+3.1% | Added |
| New York State Teachers Retirement System | 324,548 | $71.3M | 0.14% | −3,978−1.2% | Reduced |
| State Board of Administration of Florida Retirement System | 324,362 | $71.2M | 0.13% | −2,414−0.7% | Reduced |
| Assenagon Asset Management S.A. | 322,231 | $70.8M | 0.26% | +252,752+363.8% | Added |
| Principal Financial Group Inc | 306,312 | $67.3M | 0.04% | −13,734−4.3% | Reduced |
| Macquarie Group Ltd | 304,257 | $66.8M | 0.06% | −1,046,258−77.5% | Reduced |
| Russell Investments Group, Ltd. | 302,361 | $66.5M | 0.11% | +2,729+0.9% | Added |