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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $120.1B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
242.3M
+6.69M (+2.8%) vs. Q1 2026
Total value
$120.1B
+$15.0B (+14.3%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $120.1B
Q1 2021: $50.7BQ2 2021: $46.9BQ3 2021: $41.9BQ4 2021: $50.6BQ1 2022: $61.1BQ2 2022: $66.1BQ3 2022: $69.0BQ4 2022: $68.4BQ1 2023: $80.3BQ2 2023: $83.4BQ3 2023: $82.0BQ4 2023: $99.3BQ1 2024: $103.2BQ2 2024: $113.1BQ3 2024: $112.4BQ4 2024: $95.4BQ1 2025: $116.7BQ2 2025: $107.9BQ3 2025: $93.4BQ4 2025: $109.8BQ1 2026: $106.1BQ2 2026: $120.1B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$120.1B
Q1 20261,698$106.1B
Q4 20251,671$109.8B
Q3 20251,523$93.4B
Q2 20251,564$107.9B
Q1 20251,618$116.7B
Q4 20241,563$95.4B
Q3 20241,551$112.4B
Q2 20241,551$113.1B
Q1 20241,497$103.2B
Q4 20231,442$99.3B
Q3 20231,280$82.0B
Q2 20231,288$83.4B
Q1 20231,213$80.3B
Q4 20221,225$68.4B
Q3 20221,128$69.0B
Q2 20221,110$66.1B
Q1 20221,073$61.1B
Q4 20211,034$50.6B
Q3 2021936$41.9B
Q2 2021979$46.9B
Q1 20211,000$50.7B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Capital World Investors26,115,014$13.0B1.53%+746,890+2.9%Added
BlackRock, Inc.24,109,373$12.0B0.18%+139,856+0.6%Added
Capital Research Global Investors19,490,637$9.68B1.35%−1,635,327−7.7%Reduced
Vanguard Capital Management LLC16,580,713$8.24B0.18%+67,903+0.4%Added
State Street Corp11,871,459$5.90B0.17%+141,320+1.2%Added
Invesco Ltd.8,043,052$4.00B0.32%+150,441+1.9%Added
JPMorgan Chase & Co6,517,600$3.26B0.19%−515,556−7.3%Reduced
Geode Capital Management, LLC6,017,848$2.98B0.16%−121,773−2.0%Reduced
Vanguard Portfolio Management LLC4,878,987$2.42B0.11%−266,622−5.2%Reduced
Capital International Investors4,695,144$2.33B0.48%−430,933−8.4%Reduced
Loomis Sayles & Co L P3,920,953$1.95B2.44%−82,868−2.1%Reduced
Franklin Resources Inc3,347,253$1.66B0.36%+2,796,121+507.3%Added
Wellington Management Group LLP3,247,658$1.61B0.28%+35,069+1.1%Added
Morgan Stanley3,242,139$1.61B0.09%+53,258+1.7%Added
UBS Asset Management Americas Inc3,086,683$1.53B0.28%+29,287+1.0%Added
Bank of America Corp3,039,178$1.51B0.10%+160,995+5.6%Added
Jennison Associates LLC2,998,530$1.49B0.89%+258,471+9.4%Added
Norges Bank2,971,681$1.48B0.15%+2,971,681New
Alliancebernstein L.P.3,019,315$1.35B0.45%−891,471−22.8%Reduced
Ameriprise Financial Inc2,604,822$1.29B0.26%−28,659−1.1%Reduced
Northern Trust Corp2,486,478$1.24B0.14%−77,786−3.0%Reduced
Goldman Sachs Group Inc2,481,761$1.23B0.13%+63,886+2.6%Added
Clearbridge Investments, LLC2,342,915$1.16B0.96%−358,060−13.3%Reduced
Victory Capital Management Inc2,173,152$1.08B0.61%+284,631+15.1%Added
Charles Schwab Investment Management Inc2,041,282$1.01B0.13%+120,411+6.3%Added
Legal & General Group Plc1,870,015$928.9M0.19%−85,749−4.4%Reduced
Price T Rowe Associates Inc1,728,421$858.6M0.09%−31,701−1.8%Reduced
Bank of New York Mellon Corp1,672,623$830.8M0.14%+86,196+5.4%Added
Deutsche Bank AG1,579,110$784.4M0.23%+41,374+2.7%Added
Amundi1,546,509$768.2M0.18%+74,013+5.0%Added
Assenagon Asset Management S.A.1,519,128$754.6M0.49%+981,880+182.8%Added
FMR LLC1,457,158$723.8M0.03%−563,107−27.9%Reduced
Vanguard Fiduciary Trust Co1,425,390$708.0M0.16%−40,334−2.8%Reduced
Jupiter Topco LLC1,259,997$625.8M0.26%+1,259,997New
Dimensional Fund Advisors LP1,168,956$580.7M0.11%+179,614+18.2%Added
WCM Investment Management, LLC1,152,094$575.6M1.04%+30,753+2.7%Added
Nuveen, LLC1,081,685$537.3M0.13%−2,810−0.3%Reduced
Royal Bank of Canada980,259$486.9M0.08%−131,612−11.8%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.897,893$446.0M0.45%+49,846+5.9%Added
Wells Fargo & Company749,528$372.3M0.06%+4,533+0.6%Added
Arrowstreet Capital, Limited Partnership738,378$366.8M0.16%+99,428+15.6%Added
Barclays PLC733,274$364.2M0.11%+70,011+10.6%Added
Swiss National Bank717,440$356.4M0.19%−27,160−3.6%Reduced
UBS Group AG712,259$353.8M0.06%+81,641+12.9%Added
Citigroup Inc706,968$351.2M0.16%+24,161+3.5%Added
HSBC Holdings PLC676,247$335.8M0.16%+20,804+3.2%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.647,193$321.5M0.18%+49,696+8.3%Added
AQR Capital Management LLC616,170$305.0M0.11%+445,139+260.3%Added
Sumitomo Mitsui Trust Holdings, Inc.611,907$304.0M0.17%−2,541−0.4%Reduced
American Century Companies Inc580,901$288.6M0.13%−232,384−28.6%Reduced
Bellevue Group AG578,634$287.4M6.05%−103,274−15.1%Reduced
Neuberger Berman Group LLC559,445$277.9M0.19%+7,923+1.4%Added
Raymond James Financial Inc556,876$276.6M0.08%+112,380+25.3%Added
Manufacturers Life Insurance Company, The554,085$275.2M0.21%+842+0.2%Added
Vanguard Global Advisers, LLC547,463$271.9M0.13%−8,270−1.5%Reduced
Marshall Wace, LLP543,897$270.2M0.23%+226,839+71.5%Added
Pictet Asset Management Holding SA539,255$268.3M0.26%+201,686+59.7%Added
National Pension Service539,530$268.0M0.17%+7,461+1.4%Added
Edgewood Management LLC531,003$263.8M2.72%−374,126−41.3%Reduced
SG Americas Securities, LLC523,720$260.1M0.15%+466,738+819.1%Added
Life Cycle Investment Partners Ltd514,179$255.4M1.19%+73,770+16.8%Added
Citadel Advisors LLC510,430$253.5M0.15%+171,132+50.4%Added
Voya Investment Management LLC505,219$250.4M0.22%−21,828−4.1%Reduced
Vanguard Asset Management, Ltd494,186$245.5M0.17%+52,009+11.8%Added
Envestnet Asset Management Inc487,627$242.2M0.06%−15,937−3.2%Reduced
Millennium Management LLC468,410$232.7M0.16%+437,587+1,419.7%Added
DekaBank Deutsche Girozentrale506,457$225.3M0.38%00.0%Unchanged
Natixis Advisors, L.P.448,631$222.8M0.25%−105,393−19.0%Reduced
California Public Employees Retirement System447,499$222.3M0.13%−55,875−11.1%Reduced
Massachusetts Financial Services Co423,049$214.6M0.07%+95,551+29.2%Added
Bank of Montreal427,448$212.3M0.08%+36,972+9.5%Added
Chevy Chase Trust Holdings, Inc.406,303$201.8M0.52%−1,312−0.3%Reduced
Robeco Institutional Asset Management B.V.404,396$200.9M0.25%+2,752+0.7%Added
Rhumbline Advisers396,380$196.9M0.15%−26,760−6.3%Reduced
Adage Capital Partners GP, L.L.C.393,964$195.7M0.27%+141,974+56.3%Added
Hudson Bay Capital Management LP390,440$193.9M0.91%+345,440+767.6%Added
Principal Financial Group Inc389,511$193.5M0.10%−37,012−8.7%Reduced
California State Teachers Retirement System383,491$190.5M0.18%+10,010+2.7%Added
Zurcher Kantonalbank (Zurich Cantonalbank)380,762$189.1M0.36%+3,749+1.0%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main359,332$178.5M0.14%−5,181−1.4%Reduced
Canada Pension Plan Investment Board355,082$176.4M0.10%+165,031+86.8%Added
Russell Investments Group, Ltd.336,990$167.5M0.15%−30,701−8.3%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH323,752$160.7M0.25%−14,595−4.3%Reduced
Renaissance Technologies LLC320,008$159.0M0.22%−101,680−24.1%Reduced
Bank Julius Baer & Co. Ltd, Zurich319,371$158.9M0.41%+1,965+0.6%Added
AMF Pensionsforsakring AB314,765$156.4M0.93%+1,848+0.6%Added
First Trust Advisors LP289,179$143.6M0.08%−17,282−5.6%Reduced
LPL Financial LLC289,111$143.6M0.03%+21,049+7.9%Added
ProShare Advisors LLC287,847$143.0M0.21%−85,685−22.9%Reduced
Two Sigma Investments, LP285,000$141.6M0.11%−93,146−24.6%Reduced
Swedbank AB282,444$140.3M0.12%+10,891+4.0%Added
New York State Common Retirement Fund277,614$137.9M0.17%−14,800−5.1%Reduced
Baillie Gifford & Co272,561$135.4M0.12%+73,140+36.7%Added
BNP Paribas Arbitrage, SA262,258$130.3M0.07%−153,367−36.9%Reduced
Cerity Partners LLC255,874$127.1M0.15%−40,780−13.7%Reduced
Public Employees Retirement Association of Colorado250,189$124.3M0.43%−61,561−19.7%Reduced
Royal London Asset Management Ltd241,280$119.9M0.22%−10,912−4.3%Reduced
B. Metzler seel. Sohn & Co. AG231,381$114.9M0.99%−279,655−54.7%Reduced
Aviva PLC223,593$111.1M0.16%+1,141+0.5%Added
ING Groep NV223,124$110.8M0.54%+157,699+241.0%Added