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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
936
−33 vs. Q2 2021
Shares held
231.6M
+111.7K (0.0%) vs. Q2 2021
Total value
$41.9B
−$4.61B (−9.9%) vs. Q2 2021
New holders
98
359 more added
Sold out
131
348 more reduced

10 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 936 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ3 2021: $41.9B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2021.

Institutions holding VRTX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.23,547,895$4.27B0.12%+187,806+0.8%Added
Vanguard Group Inc20,442,691$3.71B0.09%+193,473+1.0%Added
State Street Corp12,323,416$2.24B0.12%+617,593+5.3%Added
Capital World Investors11,042,302$2.00B0.34%+26,924+0.2%Added
Alliancebernstein L.P.9,068,848$1.64B0.65%+2,690,416+42.2%Added
Loomis Sayles & Co L P7,005,992$1.27B1.56%+4,955,119+241.6%Added
Wellington Management Group LLP6,091,089$1.10B0.19%−2,204,600−26.6%Reduced
Price T Rowe Associates Inc5,698,247$1.03B0.10%−7,400,245−56.5%Reduced
Clearbridge Investments, LLC5,112,404$927.3M0.66%+129,810+2.6%Added
FMR LLC4,877,099$884.7M0.07%−956,964−16.4%Reduced
Geode Capital Management, LLC4,302,352$778.3M0.10%+215,173+5.3%Added
JPMorgan Chase & Co4,211,732$764.0M0.10%−226,331−5.1%Reduced
Capital International Investors3,949,552$716.4M0.16%−599,451−13.2%Reduced
Ameriprise Financial Inc3,389,090$614.7M0.20%+650,315+23.7%Added
Massachusetts Financial Services Co3,149,240$571.2M0.17%−4,547−0.1%Reduced
Bank of America Corp3,030,356$549.7M0.06%+1,497,012+97.6%Added
Northern Trust Corp2,994,490$543.2M0.10%+21,674+0.7%Added
UBS Asset Management Americas Inc2,758,853$500.4M0.21%+307,208+12.5%Added
Deutsche Bank AG2,686,591$487.3M0.23%−47,319−1.7%Reduced
Norges Bank2,526,180$458.2M0.10%−21,250−0.8%Reduced
Janus Henderson Group PLC2,134,778$387.2M0.17%−2,153,680−50.2%Reduced
Bank of New York Mellon Corp2,088,788$378.9M0.07%−25,930−1.2%Reduced
Legal & General Group Plc2,068,334$375.2M0.12%+119,277+6.1%Added
California Public Employees Retirement System2,006,318$363.9M0.27%+11,900+0.6%Added
Harding Loevner LP1,911,103$346.7M1.38%−87,975−4.4%Reduced
Renaissance Technologies LLC1,891,486$343.1M0.44%−385,798−16.9%Reduced
Bellevue Group AG1,761,616$319.5M3.24%+27,922+1.6%Added
D. E. Shaw & Co., Inc.1,714,634$311.0M0.40%+937,619+120.7%Added
ARK Investment Management LLCSuperinvestorARK Invest1,709,751$310.1M0.74%−64,315−3.6%Reduced
Canada Pension Plan Investment Board1,692,794$307.1M0.35%−89,957−5.0%Reduced
Caisse de Depot Et Placement du Quebec1,495,216$271.2M0.58%+1,438,039+2,515.1%Added
Goldman Sachs Group Inc1,393,762$252.8M0.06%+15,745+1.1%Added
Nuveen Asset Management, LLC1,365,225$247.6M0.08%−1,441,437−51.4%Reduced
Macquarie Group Ltd1,350,515$245.0M0.21%−266,259−16.5%Reduced
Charles Schwab Investment Management Inc1,241,985$225.3M0.07%+25,546+2.1%Added
Invesco Ltd.1,214,493$220.3M0.06%+48,410+4.2%Added
Man Group plc1,211,443$219.7M0.78%+371,319+44.2%Added
Wells Fargo & Company1,131,591$205.3M0.05%−41,789−3.6%Reduced
Sumitomo Mitsui Trust Holdings, Inc.1,092,041$198.1M0.12%−26,817−2.4%Reduced
Impax Asset Management Group plc1,074,736$194.9M0.80%+319,209+42.2%Added
Pictet Asset Management SA1,064,822$193.1M0.21%+1,064,822New
APG Asset Management N.V.1,228,689$192.3M0.34%−46,900−3.7%Reduced
Bank of Montreal1,053,359$192.0M0.10%+114,535+12.2%Added
Morgan Stanley1,042,513$189.1M0.03%−178,813−14.6%Reduced
Swiss National Bank1,023,675$185.7M0.12%−36,300−3.4%Reduced
Two Sigma Investments, LP959,684$174.1M0.47%+959,684New
Avidity Partners Management LP926,400$168.0M4.28%−23,600−2.5%Reduced
OrbiMed Advisors LLC877,400$159.2M1.77%−188,000−17.6%Reduced
Manning & Napier Group, LLC872,928$158.3M1.36%−24,153−2.7%Reduced
Franklin Resources Inc866,924$157.3M0.06%−251,473−22.5%Reduced
Jennison Associates LLC829,359$150.4M0.10%+37,531+4.7%Added
Two Sigma Advisers, LP782,700$142.0M0.37%+781,700+78,170.0%Added
Royal Bank of Canada780,590$141.6M0.04%−291,551−27.2%Reduced
American Century Companies Inc769,506$139.6M0.10%−130,754−14.5%Reduced
Parametric Portfolio Associates LLC734,985$133.3M0.08%−29,306−3.8%Reduced
Dimensional Fund Advisors LP704,546$127.8M0.04%+185,523+35.7%Added
Millennium Management LLC695,708$126.2M0.17%+331,296+90.9%Added
Amundi689,898$125.1M0.09%+16,172+2.4%Added
Allianz Asset Management GmbH669,444$121.4M0.10%+153,686+29.8%Added
Avoro Capital Advisors LLC664,000$120.4M1.89%−126,000−15.9%Reduced
Swedbank AB655,196$118.8M0.22%+43,410+7.1%Added
AQR Capital Management LLC639,317$116.0M0.21%−67,436−9.5%Reduced
Armistice Capital, LLC636,000$115.4M2.85%+36,000+6.0%Added
Prudential Financial Inc610,778$114.1M0.16%+177,000+40.8%Added
Parnassus Investments619,438$112.4M0.24%00.0%Unchanged
Natixis Advisors, L.P.616,708$111.9M0.46%+407,937+195.4%Added
Credit Suisse AG607,131$110.1M0.09%−72,085−10.6%Reduced
Manufacturers Life Insurance Company, The592,967$107.6M0.09%−5,773−1.0%Reduced
Candriam Luxembourg S.C.A.592,829$107.5M0.73%−215,038−26.6%Reduced
Citigroup Inc579,609$105.1M0.11%−120,472−17.2%Reduced
Barclays PLC568,703$103.2M0.07%+147,497+35.0%Added
Marshall Wace, LLP556,678$101.0M0.50%+5,719+1.0%Added
Susquehanna International Group, LLP550,229$99.8M0.13%+46,682+9.3%Added
Voloridge Investment Management, LLC536,896$97.4M0.63%+284,222+112.5%Added
Standard Life Aberdeen plc514,839$94.3M0.21%−12,600−2.4%Reduced
Putnam Investments LLC519,039$94.1M0.15%−11,020−2.1%Reduced
DnB Asset Management AS509,902$92.5M0.60%+86,593+20.5%Added
New York State Common Retirement Fund503,383$91.3M0.10%+6,248+1.3%Added
UBS Group AG502,848$91.2M0.04%+54,804+12.2%Added
First Trust Advisors LP490,671$89.0M0.10%+91,357+22.9%Added
Bank of Nova Scotia488,459$88.6M0.16%+447,537+1,093.6%Added
Public Employees Retirement Association of Colorado469,107$85.1M0.37%−5,716−1.2%Reduced
Artisan Partners Limited Partnership465,031$84.4M0.10%−1,078−0.2%Reduced
Jacobs Levy Equity Management, Inc457,122$82.9M0.56%−172,787−27.4%Reduced
Marshall Wace North America L.P.451,406$81.9M0.35%−128,419−22.1%Reduced
California State Teachers Retirement System448,582$81.4M0.10%−9,144−2.0%Reduced
Ensign Peak Advisors, Inc447,212$81.1M0.17%−158,321−26.1%Reduced
Raymond James & Associates439,481$79.7M0.07%+131,559+42.7%Added
Eaton Vance Management439,711$79.3M0.11%−250,320−36.3%Reduced
Retirement Systems of Alabama435,067$78.9M0.30%+1,095+0.3%Added
AXA S.A.421,889$76.5M0.21%+198,955+89.2%Added
Citadel Advisors LLC414,129$75.1M0.08%+24,539+6.3%Added
HSBC Holdings PLC401,059$72.9M0.08%+42,914+12.0%Added
Great West Life Assurance Co389,587$71.1M0.17%+1,011+0.3%Added
Panagora Asset Management Inc389,888$70.7M0.38%+90,980+30.4%Added
Rhumbline Advisers385,274$69.9M0.09%−15,482−3.9%Reduced
ProShare Advisors LLC373,152$67.7M0.19%+33,518+9.9%Added
National Pension Service370,946$67.3M0.13%−1,100−0.3%Reduced
DekaBank Deutsche Girozentrale344,709$63.0M0.18%+8,784+2.6%Added
Acadian Asset Management LLC337,951$61.3M0.23%+88,374+35.4%Added