Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,618
- +81 vs. Q4 2024
- Shares held
- 239.9M
- +4.97M (+2.1%) vs. Q4 2024
- Total value
- $116.3B
- +$21.7B (+23.0%) vs. Q4 2024
- New holders
- 209
- 638 more added
- Sold out
- 128
- 576 more reduced
26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 28,533,308 | $13.8B | 2.24% | +207,613+0.7% | Added |
| Vanguard Group Inc | 23,491,161 | $11.4B | 0.21% | +232,873+1.0% | Added |
| BlackRock, Inc. | 21,782,933 | $10.6B | 0.22% | −42,537−0.2% | Reduced |
| Capital Research Global Investors | 14,536,344 | $7.05B | 1.53% | +4,107,393+39.4% | Added |
| State Street Corp | 11,788,657 | $5.72B | 0.24% | −190,748−1.6% | Reduced |
| JPMorgan Chase & Co | 7,755,645 | $3.76B | 0.29% | +1,442,538+22.8% | Added |
| FMR LLC | 7,727,184 | $3.75B | 0.24% | −1,491,862−16.2% | Reduced |
| Geode Capital Management, LLC | 5,761,760 | $2.78B | 0.22% | +113,524+2.0% | Added |
| Wellington Management Group LLP | 5,454,748 | $2.64B | 0.51% | −461,336−7.8% | Reduced |
| Jennison Associates LLC | 5,062,442 | $2.45B | 1.72% | +744,680+17.2% | Added |
| Alliancebernstein L.P. | 3,953,512 | $1.92B | 0.69% | +33,492+0.9% | Added |
| Loomis Sayles & Co L P | 3,748,331 | $1.82B | 2.63% | −24,458−0.6% | Reduced |
| Morgan Stanley | 3,408,520 | $1.65B | 0.12% | +237,133+7.5% | Added |
| Norges Bank | 3,364,150 | $1.63B | 0.23% | −50,174−1.5% | Reduced |
| Amundi | 3,098,869 | $1.50B | 0.55% | −182,336−5.6% | Reduced |
| Price T Rowe Associates Inc | 2,917,227 | $1.41B | 0.17% | +1,226,527+72.5% | Added |
| Bank of America Corp | 2,864,998 | $1.39B | 0.12% | +445,645+18.4% | Added |
| Janus Henderson Group PLC | 2,747,937 | $1.35B | 0.74% | −85,952−3.0% | Reduced |
| Edgewood Management LLC | 2,644,026 | $1.28B | 4.46% | −312,582−10.6% | Reduced |
| Northern Trust Corp | 2,619,392 | $1.27B | 0.19% | −101,657−3.7% | Reduced |
| UBS Asset Management Americas Inc | 2,559,476 | $1.24B | 0.32% | +230,257+9.9% | Added |
| Ameriprise Financial Inc | 2,235,469 | $1.08B | 0.29% | +219,946+10.9% | Added |
| Massachusetts Financial Services Co | 2,024,908 | $981.7M | 0.33% | −263,590−11.5% | Reduced |
| Legal & General Group Plc | 1,894,169 | $918.3M | 0.25% | +10,016+0.5% | Added |
| Invesco Ltd. | 1,845,640 | $894.8M | 0.17% | −52,817−2.8% | Reduced |
| Parnassus Investments | 1,772,718 | $859.4M | 2.07% | −43,232−2.4% | Reduced |
| Goldman Sachs Group Inc | 1,734,594 | $841.0M | 0.16% | +332,860+23.7% | Added |
| Charles Schwab Investment Management Inc | 1,725,281 | $836.5M | 0.16% | +61,432+3.7% | Added |
| Bank of New York Mellon Corp | 1,711,665 | $829.8M | 0.16% | −47,551−2.7% | Reduced |
| Clearbridge Investments, LLC | 1,679,171 | $814.1M | 0.71% | −171,687−9.3% | Reduced |
| Deutsche Bank AG | 1,346,886 | $653.0M | 0.26% | −42,719−3.1% | Reduced |
| Royal Bank of Canada | 1,208,668 | $586.0M | 0.13% | −242,291−16.7% | Reduced |
| Renaissance Technologies LLC | 1,171,571 | $568.0M | 0.86% | −225,638−16.1% | Reduced |
| WCM Investment Management, LLC | 1,098,940 | $541.4M | 1.39% | +7,418+0.7% | Added |
| Nuveen, LLC | 998,418 | $484.1M | 0.15% | +998,418 | New |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 960,854 | $465.8M | 0.54% | −9,808−1.0% | Reduced |
| HSBC Holdings PLC | 844,675 | $408.6M | 0.27% | −29,080−3.3% | Reduced |
| Voya Investment Management LLC | 827,138 | $400.7M | 0.45% | +128,432+18.4% | Added |
| Barclays PLC | 825,930 | $400.4M | 0.18% | −17,145−2.0% | Reduced |
| California Public Employees Retirement System | 809,234 | $392.3M | 0.27% | −70,980−8.1% | Reduced |
| UBS Group AG | 737,418 | $357.5M | 0.08% | −125,618−14.6% | Reduced |
| Swiss National Bank | 726,200 | $352.1M | 0.25% | −3,000−0.4% | Reduced |
| Artisan Partners Limited Partnership | 719,131 | $348.6M | 0.57% | +54,608+8.2% | Added |
| Wells Fargo & Company | 706,169 | $342.4M | 0.08% | +16,517+2.4% | Added |
| Franklin Resources Inc | 702,034 | $340.4M | 0.10% | −58,483−7.7% | Reduced |
| Harding Loevner LP | 698,459 | $338.6M | 2.59% | −125,168−15.2% | Reduced |
| Pictet Asset Management Holding SA | 661,187 | $322.0M | 0.36% | +141,519+27.2% | Added |
| Capital International Investors | 649,899 | $315.1M | 0.06% | +307,387+89.7% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 643,987 | $312.2M | 0.22% | −15,546−2.4% | Reduced |
| Citigroup Inc | 627,715 | $304.3M | 0.23% | +165,647+35.8% | Added |
| Dimensional Fund Advisors LP | 605,879 | $293.8M | 0.07% | −21,638−3.4% | Reduced |
| Natixis Advisors, L.P. | 601,187 | $291.5M | 0.54% | +43,543+7.8% | Added |
| BNP Paribas Arbitrage, SA | 588,337 | $285.2M | 0.22% | −8,218−1.4% | Reduced |
| National Pension Service | 558,929 | $271.0M | 0.26% | +31,455+6.0% | Added |
| Manufacturers Life Insurance Company, The | 546,904 | $265.1M | 0.25% | +1,538+0.3% | Added |
| Lazard Asset Management LLC | 532,597 | $258.2M | 0.40% | +6,478+1.2% | Added |
| Raymond James Financial Inc | 510,542 | $247.5M | 0.09% | +38,636+8.2% | Added |
| DekaBank Deutsche Girozentrale | 491,129 | $238.8M | 0.47% | −15,328−3.0% | Reduced |
| Adage Capital Partners GP, L.L.C. | 489,667 | $237.4M | 0.44% | +280,428+134.0% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 489,067 | $237.1M | 0.22% | +50,976+11.6% | Added |
| TD Asset Management Inc | 485,856 | $235.6M | 0.22% | +16,788+3.6% | Added |
| Envestnet Asset Management Inc | 470,328 | $228.0M | 0.07% | +47,630+11.3% | Added |
| American Century Companies Inc | 465,741 | $225.8M | 0.14% | −7,619−1.6% | Reduced |
| Rhumbline Advisers | 451,031 | $218.7M | 0.20% | +8,670+2.0% | Added |
| Chevy Chase Trust Holdings, Inc. | 443,048 | $214.8M | 0.69% | −1,653−0.4% | Reduced |
| Neuberger Berman Group LLC | 442,628 | $214.6M | 0.18% | +8,317+1.9% | Added |
| Alyeska Investment Group, L.P. | 431,804 | $209.3M | 0.84% | +354,269+456.9% | Added |
| Public Employees Retirement Association of Colorado | 418,120 | $202.7M | 0.86% | −443−0.1% | Reduced |
| Principal Financial Group Inc | 414,371 | $200.9M | 0.11% | +17,839+4.5% | Added |
| Bank of Montreal | 413,687 | $200.6M | 0.11% | −167,494−28.8% | Reduced |
| Bellevue Group AG | 413,071 | $200.3M | 4.49% | −74,363−15.3% | Reduced |
| Bank Julius Baer & Co. Ltd, Zurich | 398,031 | $193.6M | 0.63% | +29,064+7.9% | Added |
| California State Teachers Retirement System | 398,483 | $193.2M | 0.24% | −2,187−0.5% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 392,013 | $190.1M | 0.51% | +2,356+0.6% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 384,710 | $186.5M | 0.54% | +35,233+10.1% | Added |
| ProShare Advisors LLC | 383,030 | $185.7M | 0.42% | +38,504+11.2% | Added |
| New York State Common Retirement Fund | 345,796 | $167.6M | 0.25% | −16,538−4.6% | Reduced |
| Russell Investments Group, Ltd. | 337,447 | $163.7M | 0.22% | +98,105+41.0% | Added |
| Royal London Asset Management Ltd | 335,642 | $162.7M | 0.39% | −27,636−7.6% | Reduced |
| B. Metzler seel. Sohn & Co. AG | 314,343 | $152.4M | 1.57% | +233,584+289.2% | Added |
| Millennium Management LLC | 309,935 | $150.3M | 0.15% | −708−0.2% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 306,461 | $148.6M | 0.30% | −33,047−9.7% | Reduced |
| Standard Life Aberdeen plc | 304,714 | $146.8M | 0.29% | −42,856−12.3% | Reduced |
| APG Asset Management N.V. | 326,728 | $146.6M | 0.45% | −32,557−9.1% | Reduced |
| Victory Capital Management Inc | 293,885 | $142.5M | 0.15% | −11,261−3.7% | Reduced |
| SEI Investments Co | 293,782 | $142.4M | 0.18% | +18,647+6.8% | Added |
| Great West Life Assurance Co | 270,724 | $131.5M | 0.23% | +846+0.3% | Added |
| Cerity Partners LLC | 252,924 | $122.6M | 0.25% | +14,895+6.3% | Added |
| State Board of Administration of Florida Retirement System | 248,709 | $120.6M | 0.24% | +660+0.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 237,225 | $115.0M | 0.24% | +47,965+25.3% | Added |
| Manning & Napier Advisors LLC | 235,108 | $114.0M | 1.41% | +84,982+56.6% | Added |
| Ensign Peak Advisors, Inc | 234,721 | $113.8M | 0.22% | −40,361−14.7% | Reduced |
| Macquarie Group Ltd | 234,136 | $113.5M | 0.14% | +4,203+1.8% | Added |
| Davenport & Co LLC | 225,310 | $109.6M | 0.65% | +7,242+3.3% | Added |
| Truist Financial Corp | 223,970 | $108.6M | 0.17% | +12,166+5.7% | Added |
| Korea Investment CORP | 221,180 | $107.2M | 0.26% | +14,072+6.8% | Added |
| LPL Financial LLC | 216,944 | $105.2M | 0.04% | +25,891+13.6% | Added |
| Zurich Insurance Group Ltd | 209,906 | $101.8M | 0.82% | +158,379+307.4% | Added |
| Assenagon Asset Management S.A. | 208,140 | $100.9M | 0.18% | −631,532−75.2% | Reduced |
| Handelsbanken Fonder AB | 207,645 | $100.7M | 0.41% | −88,391−29.9% | Reduced |