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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Welch & Forbes LLC207,639$100.7M1.32%+9,858+5.0%Added
New York State Teachers Retirement System204,890$99.3M0.23%−16,362−7.4%Reduced
Intermede Investment Partners Ltd204,045$98.9M3.11%+204,045New
Candriam Luxembourg S.C.A.198,287$96.1M0.60%−60,335−23.3%Reduced
Congress Asset Management Co187,576$90.9M0.68%+40,427+27.5%Added
Skandinaviska Enskilda Banken AB (publ)186,471$90.4M0.45%+15,437+9.0%Added
Capital International Sarl186,171$90.3M2.04%+17,579+10.4%Added
Aviva PLC180,690$87.6M0.21%+25,200+16.2%Added
Bowen Hanes & Co Inc178,909$86.7M2.41%−1,715−0.9%Reduced
DnB Asset Management AS176,531$85.6M0.39%−24,411−12.1%Reduced
Federated Hermes, Inc.170,233$82.5M0.18%−18,842−10.0%Reduced
Prudential Financial Inc168,855$81.9M0.12%+717+0.4%Added
Mitsubishi UFJ Trust & Banking Corp161,898$78.5M0.20%−9,708−5.7%Reduced
AXA S.A.160,793$78.0M0.26%+20,003+14.2%Added
OrbiMed Advisors LLC159,900$77.5M1.86%+8,900+5.9%Added
Danske Bank A/S159,790$77.5M0.24%−2,513−1.5%Reduced
Provident Investment Management, Inc.156,325$75.8M7.14%+1,259+0.8%Added
Canada Pension Plan Investment Board154,429$74.9M0.07%−214,925−58.2%Reduced
Nomura Asset Management Co Ltd153,295$74.3M0.23%+3,496+2.3%Added
Woodline Partners LP153,160$74.3M0.48%+3,742+2.5%Added
State of Wisconsin Investment Board152,677$74.0M0.19%+437+0.3%Added
Schroder Investment Management Group149,387$73.6M0.07%−14,241−8.7%Reduced
Healthcare of Ontario Pension Plan Trust Fund149,540$72.5M0.16%+77,331+107.1%Added
British Columbia Investment Management Corp148,653$72.1M0.44%+21,329+16.8%Added
Birch Hill Investment Advisors LLC148,304$71.9M3.41%−24,517−14.2%Reduced
Robeco Institutional Asset Management B.V.146,000$70.8M0.14%−140,756−49.1%Reduced
First Trust Advisors LP144,808$70.2M0.06%−47,978−24.9%Reduced
AQR Capital Management LLC145,871$69.6M0.07%−99,914−40.7%Reduced
Mirae Asset Global Investments Co., Ltd.143,318$69.5M0.28%+23,769+19.9%Added
Colony Group, LLC143,205$69.4M0.17%+2,093+1.5%Added
Asset Management One Co.,Ltd.141,873$68.8M0.24%+6,590+4.9%Added
Van Eck Associates Corp141,691$68.7M0.09%−17,578−11.0%Reduced
Allianz Asset Management GmbH141,085$68.4M0.10%−114,538−44.8%Reduced
National Bank of Canada140,627$68.2M0.08%−14,173−9.2%Reduced
Marshall Wace, LLP138,000$66.9M0.09%−56,000−28.9%Reduced
Abn Amro Investment Solutions137,642$66.7M1.39%−2,595−1.9%Reduced
Lansforsakringar Fondforvaltning AB (publ)136,311$66.1M0.41%−8,397−5.8%Reduced
Baillie Gifford & Co134,465$65.2M0.06%−15,373−10.3%Reduced
Raiffeisen Bank International AG131,609$64.8M1.03%−2,289−1.7%Reduced
Capital International Inc131,225$63.6M0.77%+7,091+5.7%Added
AustralianSuper Pty Ltd127,943$62.0M0.35%−91,132−41.6%Reduced
ABN AMRO Bank N.V.127,393$61.7M0.85%+3,341+2.7%Added
Carmignac Gestion126,954$61.6M1.01%−70,512−35.7%Reduced
PFM Health Sciences, LP126,989$61.6M4.72%00.0%Unchanged
Teacher Retirement System of Texas126,824$61.5M0.26%+21,929+20.9%Added
Polar Capital Holdings Plc125,000$60.6M0.38%−50,000−28.6%Reduced
Caisse de Depot Et Placement du Quebec124,847$60.5M0.13%−16,870−11.9%Reduced
Employees Retirement System of Texas120,200$58.3M0.53%−1,400−1.2%Reduced
KBC Group NV119,305$57.8M0.18%−124−0.1%Reduced
Treasurer of the State of North Carolina118,375$57.4M0.23%+1,582+1.4%Added
Hardman Johnston Global Advisors LLC118,080$57.2M2.73%+3,416+3.0%Added
Mariner, LLC116,561$56.5M0.09%−5,856−4.8%Reduced
Capital International Ltd112,546$54.6M2.38%+1,975+1.8%Added
Public Employees Retirement System of Ohio109,282$53.0M0.19%−6,565−5.7%Reduced
Allspring Global Investments Holdings, LLC108,529$52.6M0.09%+11,903+12.3%Added
Stifel Financial Corp106,991$51.9M0.06%−17,853−14.3%Reduced
CI Private Wealth, LLC106,550$51.7M0.08%−6,596−5.8%Reduced
Guggenheim Capital LLC102,003$49.5M0.46%−33,692−24.8%Reduced
Storebrand Asset Management AS101,120$49.0M0.16%−33,931−25.1%Reduced
Toronto Dominion Bank99,154$48.1M0.12%−8,680−8.0%Reduced
State of Tennessee, Treasury Department98,349$47.7M0.18%+5,160+5.5%Added
Banco Bilbao Vizcaya Argentaria, S.A.98,221$47.7M0.48%+10,425+11.9%Added
FIL Ltd93,408$45.3M0.04%+135+0.1%Added
Resona Asset Management Co.,Ltd.90,762$44.1M0.26%+4,535+5.3%Added
Rockefeller Capital Management L.P.90,964$44.1M0.11%−7,825−7.9%Reduced
Country Trust Bank89,824$43.5M1.10%+6,222+7.4%Added
Creative Planning88,840$43.1M0.04%+9,370+11.8%Added
KLP Kapitalforvaltning AS87,741$42.5M0.21%+800+0.9%Added
Thrivent Financial for Lutherans87,083$42.2M0.09%−817−0.9%Reduced
State of New Jersey Common Pension Fund D86,729$42.0M0.19%−8,538−9.0%Reduced
Zacks Investment Management86,050$41.7M0.39%+33,397+63.4%Added
CIBC Asset Management Inc85,379$41.4M0.14%+888+1.1%Added
Assetmark, Inc85,297$41.4M0.11%+5,432+6.8%Added
Corebridge Financial, Inc.84,328$40.9M0.24%−3,718−4.2%Reduced
Epoch Investment Partners, Inc.81,836$39.7M0.21%−4,641−5.4%Reduced
Wealth Enhancement Advisory Services, LLC80,189$38.9M0.07%00.0%Unchanged
GuoLine Advisory Pte Ltd79,700$38.6M4.09%00.0%Unchanged
William Blair Investment Management, LLC79,332$38.5M0.11%+1,800+2.3%Added
The PNC Financial Services Group, Inc.78,161$37.9M0.02%−461−0.6%Reduced
Beacon Investment Advisory Services, Inc.77,901$37.8M1.77%−923−1.2%Reduced
STRS Ohio77,851$37.7M0.16%−680−0.9%Reduced
Arizona State Retirement System75,537$36.6M0.23%+930+1.2%Added
Vontobel Holding Ltd.74,806$36.3M0.13%−114,143−60.4%Reduced
Westwood Holdings Group Inc.73,968$35.9M0.27%+70,803+2,237.1%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund73,888$35.8M0.43%+5,800+8.5%Added
MetLife Investment Management72,361$35.1M0.19%−1,523−2.1%Reduced
State of Michigan Retirement System72,123$35.0M0.20%−300−0.4%Reduced
D. E. Shaw & Co., Inc.71,933$34.9M0.04%−193,751−72.9%Reduced
Daiwa Securities Group Inc.71,232$34.5M0.15%+5,504+8.4%Added
Ossiam71,208$34.5M0.48%+6,375+9.8%Added
Rafferty Asset Management, LLC70,830$34.3M0.15%−19,389−21.5%Reduced
Erste Asset Management GmbH68,770$33.5M0.43%+2,996+4.6%Added
Janney Montgomery Scott LLC68,619$33.3M0.09%−23,573−25.6%Reduced
Nisa Investment Advisors, LLC68,300$33.1M0.17%−1,922−2.7%Reduced
Rhenman & Partners Asset Management AB66,750$32.4M3.72%+16,750+33.5%Added
Jacobs Levy Equity Management, Inc66,234$32.1M0.13%+66,234New
Gateway Investment Advisers LLC65,853$31.9M0.37%+110.0%Added
Commonwealth Equity Services, LLC65,744$31.9M0.05%+1,624+2.5%Added
Comerica Bank65,421$31.7M0.13%+15,843+32.0%Added
Cetera Investment Advisers64,774$31.4M0.06%+10,817+20.0%Added