Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,698
- +51 vs. Q4 2025
- Shares held
- 237.8M
- +23.8M (+11.1%) vs. Q4 2025
- Total value
- $106.1B
- +$9.16B (+9.4%) vs. Q4 2025
- New holders
- 155
- 683 more added
- Sold out
- 104
- 600 more reduced
24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 25,368,124 | $11.3B | 1.55% | −142,058−0.6% | Reduced |
| BlackRock, Inc. | 23,969,517 | $10.7B | 0.19% | +217,528+0.9% | Added |
| Capital Research Global Investors | 21,125,964 | $9.43B | 1.46% | +3,809,620+22.0% | Added |
| Vanguard Capital Management LLC | 16,512,810 | $7.37B | 0.18% | +16,512,810 | New |
| State Street Corp | 11,730,139 | $5.24B | 0.18% | +40,600+0.3% | Added |
| Invesco Ltd. | 7,892,611 | $3.52B | 0.34% | +39,878+0.5% | Added |
| JPMorgan Chase & Co | 7,033,156 | $3.12B | 0.21% | +993,675+16.5% | Added |
| Geode Capital Management, LLC | 6,139,621 | $2.73B | 0.17% | +157,716+2.6% | Added |
| Vanguard Portfolio Management LLC | 5,145,609 | $2.30B | 0.12% | +5,145,609 | New |
| Capital International Investors | 5,126,077 | $2.29B | 0.54% | +392,481+8.3% | Added |
| Loomis Sayles & Co L P | 4,003,821 | $1.79B | 2.41% | −29,704−0.7% | Reduced |
| Alliancebernstein L.P. | 3,910,786 | $1.77B | 0.57% | −585,696−13.0% | Reduced |
| Wellington Management Group LLP | 3,212,589 | $1.43B | 0.27% | −609,142−15.9% | Reduced |
| Morgan Stanley | 3,188,881 | $1.42B | 0.09% | +68,571+2.2% | Added |
| UBS Asset Management Americas Inc | 3,057,396 | $1.37B | 0.28% | +56,618+1.9% | Added |
| Bank of America Corp | 2,878,183 | $1.29B | 0.09% | −58,847−2.0% | Reduced |
| Jennison Associates LLC | 2,740,059 | $1.22B | 0.84% | −509,482−15.7% | Reduced |
| Clearbridge Investments, LLC | 2,700,975 | $1.21B | 1.05% | −159,201−5.6% | Reduced |
| Ameriprise Financial Inc | 2,633,481 | $1.18B | 0.27% | +369,749+16.3% | Added |
| Northern Trust Corp | 2,564,264 | $1.15B | 0.15% | −15,193−0.6% | Reduced |
| Goldman Sachs Group Inc | 2,417,875 | $1.08B | 0.14% | +663,757+37.8% | Added |
| Janus Henderson Group PLC | 2,131,527 | $951.8M | 0.45% | −90,426−4.1% | Reduced |
| FMR LLC | 2,020,265 | $902.1M | 0.05% | −192,331−8.7% | Reduced |
| Legal & General Group Plc | 1,955,764 | $873.3M | 0.20% | −14,341−0.7% | Reduced |
| Charles Schwab Investment Management Inc | 1,920,871 | $857.7M | 0.13% | +61,650+3.3% | Added |
| Victory Capital Management Inc | 1,888,521 | $843.3M | 0.54% | −1,468,245−43.7% | Reduced |
| Price T Rowe Associates Inc | 1,760,122 | $786.0M | 0.09% | −518,836−22.8% | Reduced |
| Bank of New York Mellon Corp | 1,586,427 | $708.4M | 0.13% | +58,841+3.9% | Added |
| Deutsche Bank AG | 1,537,736 | $686.7M | 0.23% | −231,145−13.1% | Reduced |
| Amundi | 1,472,496 | $657.5M | 0.18% | +168,335+12.9% | Added |
| Vanguard Fiduciary Trust Co | 1,465,724 | $654.5M | 0.17% | +1,465,724 | New |
| WCM Investment Management, LLC | 1,121,341 | $496.9M | 1.13% | −7,804−0.7% | Reduced |
| Royal Bank of Canada | 1,111,871 | $496.5M | 0.09% | −82,641−6.9% | Reduced |
| Nuveen, LLC | 1,084,495 | $484.3M | 0.13% | +42,098+4.0% | Added |
| Dimensional Fund Advisors LP | 989,342 | $441.8M | 0.09% | +43,682+4.6% | Added |
| Edgewood Management LLC | 905,129 | $404.2M | 2.61% | −154,946−14.6% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 848,047 | $378.7M | 0.44% | +178,240+26.6% | Added |
| American Century Companies Inc | 813,285 | $363.2M | 0.19% | −35,354−4.2% | Reduced |
| Wells Fargo & Company | 744,995 | $332.7M | 0.07% | +3,182+0.4% | Added |
| Swiss National Bank | 744,600 | $332.5M | 0.19% | +42,000+6.0% | Added |
| Citigroup Inc | 682,807 | $304.9M | 0.19% | +142,877+26.5% | Added |
| Bellevue Group AG | 681,908 | $304.5M | 7.25% | +788+0.1% | Added |
| Barclays PLC | 663,263 | $296.2M | 0.11% | −184,495−21.8% | Reduced |
| HSBC Holdings PLC | 655,443 | $292.7M | 0.17% | +25,154+4.0% | Added |
| Arrowstreet Capital, Limited Partnership | 638,950 | $285.3M | 0.15% | +45,003+7.6% | Added |
| UBS Group AG | 630,618 | $281.6M | 0.05% | +74,636+13.4% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 614,448 | $274.4M | 0.18% | −40,022−6.1% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 597,497 | $266.8M | 0.18% | +31,270+5.5% | Added |
| Vanguard Global Advisers, LLC | 555,733 | $248.2M | 0.13% | +555,733 | New |
| Natixis Advisors, L.P. | 554,024 | $247.4M | 0.34% | +26,160+5.0% | Added |
| Manufacturers Life Insurance Company, The | 553,243 | $247.0M | 0.21% | −4,470−0.8% | Reduced |
| Neuberger Berman Group LLC | 551,522 | $246.3M | 0.19% | +5,625+1.0% | Added |
| Franklin Resources Inc | 551,132 | $246.1M | 0.06% | +532+0.1% | Added |
| Assenagon Asset Management S.A. | 537,248 | $239.9M | 0.38% | −295,605−35.5% | Reduced |
| National Pension Service | 532,069 | $237.6M | 0.18% | +1,228+0.2% | Added |
| Voya Investment Management LLC | 527,047 | $234.9M | 0.24% | −35,305−6.3% | Reduced |
| DekaBank Deutsche Girozentrale | 506,457 | $230.0M | 0.38% | 00.0% | Unchanged |
| B. Metzler seel. Sohn & Co. AG | 511,036 | $228.2M | 2.12% | −4,233−0.8% | Reduced |
| Envestnet Asset Management Inc | 503,564 | $224.9M | 0.06% | +31,921+6.8% | Added |
| California Public Employees Retirement System | 503,374 | $224.8M | 0.14% | −52,690−9.5% | Reduced |
| Raymond James Financial Inc | 444,496 | $198.5M | 0.06% | +26,365+6.3% | Added |
| Vanguard Asset Management, Ltd | 442,177 | $197.4M | 0.17% | +442,177 | New |
| Life Cycle Investment Partners Ltd | 440,409 | $196.7M | 1.25% | +73,555+20.1% | Added |
| Principal Financial Group Inc | 426,523 | $190.5M | 0.10% | +11,423+2.8% | Added |
| Rhumbline Advisers | 423,140 | $188.9M | 0.16% | −8,122−1.9% | Reduced |
| Renaissance Technologies LLC | 421,688 | $188.3M | 0.29% | −83,360−16.5% | Reduced |
| BNP Paribas Arbitrage, SA | 415,625 | $185.6M | 0.12% | −143,918−25.7% | Reduced |
| Chevy Chase Trust Holdings, Inc. | 407,615 | $182.0M | 0.52% | −748−0.2% | Reduced |
| Robeco Institutional Asset Management B.V. | 401,644 | $179.4M | 0.26% | +7,444+1.9% | Added |
| Bank of Montreal | 390,476 | $174.4M | 0.07% | −37,004−8.7% | Reduced |
| Two Sigma Investments, LP | 378,146 | $168.9M | 0.14% | +373,991+9,001.0% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 377,013 | $168.4M | 0.37% | +23,525+6.7% | Added |
| ProShare Advisors LLC | 373,532 | $166.8M | 0.25% | −83,514−18.3% | Reduced |
| California State Teachers Retirement System | 373,481 | $166.8M | 0.18% | −12,270−3.2% | Reduced |
| Russell Investments Group, Ltd. | 367,691 | $164.0M | 0.18% | −13,771−3.6% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 364,513 | $162.8M | 0.15% | −439,260−54.6% | Reduced |
| Citadel Advisors LLC | 339,298 | $151.5M | 0.11% | −87,762−20.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 338,347 | $151.0M | 0.26% | +3,449+1.0% | Added |
| Pictet Asset Management Holding SA | 337,569 | $150.1M | 0.16% | −414,856−55.1% | Reduced |
| Massachusetts Financial Services Co | 327,498 | $149.4M | 0.05% | +115,564+54.5% | Added |
| Marshall Wace, LLP | 317,058 | $141.6M | 0.15% | +113,026+55.4% | Added |
| Bank Julius Baer & Co. Ltd, Zurich | 317,406 | $141.5M | 0.43% | −48,935−13.4% | Reduced |
| Harding Loevner LP | 313,546 | $140.0M | 1.44% | −78,319−20.0% | Reduced |
| AMF Pensionsforsakring AB | 312,917 | $139.7M | 0.93% | +166,968+114.4% | Added |
| Public Employees Retirement Association of Colorado | 311,750 | $139.2M | 0.55% | −17,995−5.5% | Reduced |
| First Trust Advisors LP | 306,461 | $136.8M | 0.10% | +105,171+52.2% | Added |
| Cerity Partners LLC | 296,654 | $132.5M | 0.19% | +35,101+13.4% | Added |
| New York State Common Retirement Fund | 292,414 | $130.6M | 0.18% | −5,000−1.7% | Reduced |
| National Bank of Canada | 272,117 | $121.5M | 0.12% | +33,569+14.1% | Added |
| Swedbank AB | 271,553 | $121.3M | 0.13% | +10,810+4.1% | Added |
| LPL Financial LLC | 268,062 | $119.7M | 0.03% | −8,816−3.2% | Reduced |
| Royal London Asset Management Ltd | 252,192 | $112.6M | 0.24% | −21,241−7.8% | Reduced |
| Adage Capital Partners GP, L.L.C. | 251,990 | $112.5M | 0.17% | −20,484−7.5% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 251,711 | $112.4M | 0.26% | −93,672−27.1% | Reduced |
| D. E. Shaw & Co., Inc. | 248,960 | $111.2M | 0.09% | +248,960 | New |
| Man Group plc | 236,798 | $105.7M | 0.22% | −143,937−37.8% | Reduced |
| Standard Life Aberdeen plc | 233,480 | $104.3M | 0.17% | −28,577−10.9% | Reduced |
| Candriam Luxembourg S.C.A. | 228,915 | $102.2M | 0.53% | +3,623+1.6% | Added |
| TD Asset Management Inc | 228,195 | $101.9M | 0.08% | +45,582+25.0% | Added |
| State Board of Administration of Florida Retirement System | 224,655 | $100.3M | 0.19% | −1,345−0.6% | Reduced |