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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Redwood Park Advisors LLC1$4470.00%−1−50.0%Reduced
ROSS\JOHNSON & Associates LLC1$4470.01%−1−50.0%Reduced
Breakwater Investment Management1$4470.00%00.0%Unchanged
NorthAvenue LLC1$4470.00%00.0%Unchanged
Osbon Capital Management LLC1$4470.00%00.0%Unchanged
Napier Financial, LLC1$4470.00%+1New
Cherry Tree Wealth Management, LLC2$6700.00%00.0%Unchanged
Delta Asset Management LLC2$8930.00%00.0%Unchanged
WFA of San Diego, LLC2$8930.00%00.0%Unchanged
West Branch Capital LLC2$8940.00%00.0%Unchanged
Seneschal Advisors, LLC2$8940.00%00.0%Unchanged
Phillip James Consulting Co.2$1.00K0.00%+2New
PEAK6 LLC3$1.25K0.00%−269−98.9%Reduced
Arcadia Investment Management Corp3$1.34K0.00%00.0%Unchanged
Anfield Capital Management, LLC3$1.34K0.00%00.0%Unchanged
Barnes Dennig Private Wealth Management LLC3$1.34K0.00%00.0%Unchanged
Davis Capital Management3$1.34K0.00%+1+50.0%Added
TopTier Wealth Management, LLC3$1.34K0.00%+3New
LGT Financial Advisors LLC4$1.79K0.01%00.0%Unchanged
Sofos Investments, Inc.4$1.79K0.00%+4New
Hickory Point Bank & Trust4$1.79K0.00%+4New
Mowery & Schoenfeld Wealth Management, LLC4$1.79K0.00%−17−81.0%Reduced
Navigoe, LLC5$2.00K0.00%00.0%Unchanged
PayPay Securities Corp5$2.18K0.08%−1−16.7%Reduced
Three Bearings Fiduciary Advisors, Inc.5$2.23K0.00%00.0%Unchanged
Bernard Wealth Management Corp.5$2.23K0.00%00.0%Unchanged
Curio Wealth, LLC5$2.23K0.00%+1+25.0%Added
S&T Bank5$2.23K0.00%+1+25.0%Added
Capital & Planning, LLC5$2.23K0.00%+5New
Kentucky Trust Co5$2.23K0.00%+5New
Vision Retirement, LLC5$2.23K0.00%+5New
Signature Resources Capital Management, LLC6$2.68K0.00%−18−75.0%Reduced
NVWM, LLC6$2.68K0.00%00.0%Unchanged
Louisbourg Investments Inc.6$2.68K0.00%00.0%Unchanged
Key Capital Management, INC6$2.68K0.00%00.0%Unchanged
Retirement Wealth Solutions LLC6$2.68K0.00%+6New
Corsicana & Co.6$2.91K0.00%00.0%Unchanged
Torren Management, LLC7$3.13K0.00%−70−90.9%Reduced
Imprint Wealth LLC7$3.13K0.01%00.0%Unchanged
Bruce G. Allen Investments, LLC7$3.13K0.00%00.0%Unchanged
Maseco LLP7$3.13K0.00%00.0%Unchanged
1015 Capital Partners, LLC7$3.13K0.00%+1+16.7%Added
Reyes Financial Architecture, Inc.8$3.57K0.00%−7−46.7%Reduced
Hara Capital LLC8$3.57K0.00%00.0%Unchanged
Granite FO LLC8$3.57K0.00%00.0%Unchanged
Bank of Jackson Hole Trust8$3.57K0.00%00.0%Unchanged
HFM Investment Advisors, LLC8$3.57K0.00%00.0%Unchanged
JNBA Financial Advisors8$3.57K0.00%+8New
Financial Consulate, Inc8$3.57K0.00%+8New
Hartford Financial Management Inc.9$4.02K0.00%−3−25.0%Reduced
Altshuler Shaham Ltd9$4.02K0.00%+9New
C M Bidwell & Associates Ltd10$4.46K0.00%00.0%Unchanged
Minot DeBlois Advisors LLC10$4.46K0.00%00.0%Unchanged
Carolina Wealth Advisors, LLC10$4.46K0.00%00.0%Unchanged
Align Financial, LLC10$4.46K0.00%−4,524−99.8%Reduced
Hughes Financial Services, LLC10$4.46K0.00%+5+100.0%Added
Newbridge Financial Services Group, Inc.10$4.46K0.00%+10New
POM Investment Strategies, LLC10$4.46K0.01%+10New
DecisionPoint Financial, LLC10$4.47K0.00%+1+11.1%Added
American Capital Advisory, LLC10$4.47K0.00%+3+42.9%Added
Union Savings Bank11$4.91K0.00%00.0%Unchanged
Bare Financial Services, Inc11$4.91K0.00%−8−42.1%Reduced
NBT Bank N A11$4.91K0.00%+11New
Financial Perspectives, Inc11$4.91K0.00%+11New
Security National Bank12$5.36K0.00%00.0%Unchanged
Tiaa Trust, National Association12$5.36K0.00%−5,117−99.8%Reduced
Kozak & Associates, Inc.13$5.72K0.00%00.0%Unchanged
Strengthening Families & Communities, LLC13$5.80K0.00%−74−85.1%Reduced
Clark Wealth Partners13$5.81K0.00%00.0%Unchanged
United Community Bank14$6.25K0.00%−21−60.0%Reduced
WealthCollab, LLC14$6.25K0.00%−6−30.0%Reduced
Creative Financial Designs Inc14$6.25K0.00%00.0%Unchanged
Motco14$6.25K0.00%00.0%Unchanged
Magnolia Wealth Management, LLC15$6.70K0.00%+15New
Hollencrest Capital Management16$7.14K0.00%00.0%Unchanged
Principia Wealth Advisory, LLC16$7.14K0.00%+3+23.1%Added
Mascoma Wealth Management LLC17$7.59K0.00%00.0%Unchanged
Atomic Invest LLC18$7.90K0.00%+3+20.0%Added
Bay Harbor Wealth Management, LLC18$8.04K0.00%+3+20.0%Added
Jackson, Grant Investment Advisers, Inc.18$8.04K0.00%00.0%Unchanged
Vermillion Wealth Management, Inc.18$8.04K0.00%+18New
Intentional Wealth Strategies, LLC18$8.04K0.01%+18New
RMG Wealth Management LLC19$8.27K0.00%+10+111.1%Added
WestEnd Advisors, LLC19$8.48K0.00%00.0%Unchanged
Rakuten Securities, Inc.20$8.93K0.00%−1−4.8%Reduced
J.Safra Asset Management Corp20$8.93K0.00%00.0%Unchanged
Clal Insurance Enterprises Holdings Ltd21$9.00K0.00%−4,002−99.5%Reduced
Penserra Capital Management LLC21$9.00K0.00%00.0%Unchanged
Caldwell Sutter Capital, Inc.21$9.38K0.00%00.0%Unchanged
Osterweis Capital Management Inc21$9.38K0.00%00.0%Unchanged
Aspect Partners, LLC21$9.38K0.00%00.0%Unchanged
Cetera Trust Company, N.A21$9.38K0.01%00.0%Unchanged
Colonial Trust Co21$9.48K0.00%−32−60.4%Reduced
Westfuller Advisors, LLC22$9.66K0.00%−1−4.3%Reduced
Dynamic Wealth Strategies, LLC22$9.82K0.01%00.0%Unchanged
Portus Wealth Advisors, LLC22$9.82K0.01%+22New
LFA - Lugano Financial Advisors SA23$10.3K0.01%00.0%Unchanged
McGuire Capital Advisors Inc23$10.3K0.01%+11+91.7%Added
Hoey Investments, Inc23$10.3K0.00%+10+76.9%Added
Creative Capital Management Investments LLC24$10.7K0.00%00.0%Unchanged