Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −13 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 156
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 25,910,587 | $10.1B | 1.39% | −2,821,556−9.8% | Reduced |
| Vanguard Group Inc | 24,216,865 | $9.48B | 0.14% | +243,088+1.0% | Added |
| BlackRock, Inc. | 22,253,047 | $8.72B | 0.15% | +381,102+1.7% | Added |
| Capital Research Global Investors | 16,553,281 | $6.48B | 1.22% | +444,990+2.8% | Added |
| State Street Corp | 11,606,000 | $4.55B | 0.16% | −169,227−1.4% | Reduced |
| JPMorgan Chase & Co | 6,434,778 | $2.52B | 0.16% | +565,417+9.6% | Added |
| Geode Capital Management, LLC | 5,973,745 | $2.33B | 0.15% | +44,998+0.8% | Added |
| Wellington Management Group LLP | 4,772,042 | $1.87B | 0.33% | −41,344−0.9% | Reduced |
| Capital International Investors | 4,689,059 | $1.84B | 0.30% | +2,053,156+77.9% | Added |
| Alliancebernstein L.P. | 4,522,586 | $1.77B | 0.56% | +144,266+3.3% | Added |
| Loomis Sayles & Co L P | 4,122,128 | $1.61B | 1.92% | +308,750+8.1% | Added |
| Jennison Associates LLC | 3,454,947 | $1.35B | 0.79% | −2,696,558−43.8% | Reduced |
| FMR LLC | 3,303,768 | $1.29B | 0.07% | −3,102,604−48.4% | Reduced |
| Morgan Stanley | 3,108,405 | $1.22B | 0.07% | −223,034−6.7% | Reduced |
| Price T Rowe Associates Inc | 3,043,805 | $1.19B | 0.13% | −116,065−3.7% | Reduced |
| UBS Asset Management Americas Inc | 2,887,117 | $1.13B | 0.25% | −180,356−5.9% | Reduced |
| Bank of America Corp | 2,840,424 | $1.11B | 0.08% | +32,807+1.2% | Added |
| Clearbridge Investments, LLC | 2,645,764 | $1.04B | 0.78% | +1,117,900+73.2% | Added |
| Northern Trust Corp | 2,627,887 | $1.03B | 0.13% | −30,694−1.2% | Reduced |
| Ameriprise Financial Inc | 2,276,927 | $891.7M | 0.21% | +95,565+4.4% | Added |
| Janus Henderson Group PLC | 2,119,107 | $829.9M | 0.38% | −500,427−19.1% | Reduced |
| Invesco Ltd. | 2,096,797 | $821.2M | 0.13% | +112,751+5.7% | Added |
| Victory Capital Management Inc | 2,247,566 | $787.3M | 0.49% | +92,402+4.3% | Added |
| Legal & General Group Plc | 1,952,297 | $764.6M | 0.17% | +62,520+3.3% | Added |
| Charles Schwab Investment Management Inc | 1,829,931 | $716.7M | 0.11% | +56,306+3.2% | Added |
| Parnassus Investments | 1,648,433 | $645.6M | 1.49% | −63,007−3.7% | Reduced |
| Deutsche Bank AG | 1,600,456 | $626.8M | 0.21% | +192,822+13.7% | Added |
| Bank of New York Mellon Corp | 1,569,165 | $614.5M | 0.11% | −31,308−2.0% | Reduced |
| Edgewood Management LLC | 1,487,542 | $582.6M | 2.06% | −967,405−39.4% | Reduced |
| Goldman Sachs Group Inc | 1,484,658 | $581.5M | 0.08% | −447,102−23.1% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 1,341,470 | $525.4M | 0.47% | +135,674+11.3% | Added |
| Royal Bank of Canada | 1,193,709 | $467.5M | 0.08% | −190,659−13.8% | Reduced |
| WCM Investment Management, LLC | 1,150,132 | $454.7M | 0.95% | −13,538−1.2% | Reduced |
| Amundi | 1,118,971 | $450.8M | 0.14% | −14,255−1.3% | Reduced |
| Nuveen, LLC | 1,077,710 | $422.1M | 0.11% | +15,475+1.5% | Added |
| Pictet Asset Management Holding SA | 791,458 | $310.5M | 0.30% | +55,636+7.6% | Added |
| Dimensional Fund Advisors LP | 783,586 | $306.9M | 0.07% | +187,359+31.4% | Added |
| UBS Group AG | 773,048 | $302.8M | 0.06% | +73,046+10.4% | Added |
| Assenagon Asset Management S.A. | 763,703 | $299.1M | 0.44% | +520,949+214.6% | Added |
| Barclays PLC | 742,487 | $290.8M | 0.11% | −80,450−9.8% | Reduced |
| Swiss National Bank | 740,300 | $289.9M | 0.17% | −38,000−4.9% | Reduced |
| Renaissance Technologies LLC | 735,888 | $288.2M | 0.38% | −269,000−26.8% | Reduced |
| Wells Fargo & Company | 717,326 | $280.9M | 0.06% | +15,274+2.2% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 700,673 | $274.4M | 0.16% | +45,623+7.0% | Added |
| HSBC Holdings PLC | 637,332 | $249.5M | 0.15% | −4,629−0.7% | Reduced |
| California Public Employees Retirement System | 612,507 | $239.9M | 0.14% | −112,548−15.5% | Reduced |
| Squarepoint Ops LLC | 607,836 | $238.1M | 0.51% | +432,149+246.0% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 544,978 | $213.4M | 0.15% | +20,053+3.8% | Added |
| Lazard Asset Management LLC | 544,823 | $213.4M | 0.29% | +64,513+13.4% | Added |
| Citigroup Inc | 539,995 | $211.5M | 0.15% | −59,084−9.9% | Reduced |
| Natixis Advisors, L.P. | 537,194 | $210.4M | 0.31% | −3,336−0.6% | Reduced |
| Raymond James Financial Inc | 535,685 | $209.8M | 0.07% | +35,908+7.2% | Added |
| Neuberger Berman Group LLC | 527,491 | $206.6M | 0.15% | +68,341+14.9% | Added |
| National Pension Service | 512,113 | $200.6M | 0.16% | +14,313+2.9% | Added |
| Manufacturers Life Insurance Company, The | 510,165 | $199.8M | 0.16% | −36,791−6.7% | Reduced |
| DekaBank Deutsche Girozentrale | 506,457 | $199.7M | 0.34% | 00.0% | Unchanged |
| Bellevue Group AG | 505,805 | $198.1M | 4.12% | +64,195+14.5% | Added |
| Massachusetts Financial Services Co | 503,160 | $197.1M | 0.06% | −781,194−60.8% | Reduced |
| Adage Capital Partners GP, L.L.C. | 482,495 | $189.0M | 0.30% | +304,303+170.8% | Added |
| Manning & Napier Advisors LLC | 474,822 | $187.7M | 2.39% | +241,242+103.3% | Added |
| Envestnet Asset Management Inc | 470,755 | $184.4M | 0.05% | +21,767+4.8% | Added |
| Franklin Resources Inc | 462,954 | $181.3M | 0.05% | −60,879−11.6% | Reduced |
| Harding Loevner LP | 455,988 | $178.6M | 1.31% | −255,623−35.9% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 456,333 | $178.6M | 0.46% | +11,874+2.7% | Added |
| American Century Companies Inc | 449,193 | $175.9M | 0.09% | −88,939−16.5% | Reduced |
| Rhumbline Advisers | 447,928 | $175.4M | 0.14% | −6,444−1.4% | Reduced |
| Voya Investment Management LLC | 432,257 | $168.8M | 0.17% | −267,387−38.2% | Reduced |
| Bank of Montreal | 419,458 | $164.3M | 0.07% | +56,423+15.5% | Added |
| Chevy Chase Trust Holdings, Inc. | 418,509 | $163.9M | 0.45% | −22,418−5.1% | Reduced |
| Principal Financial Group Inc | 406,500 | $159.2M | 0.08% | −3,305−0.8% | Reduced |
| California State Teachers Retirement System | 394,582 | $154.5M | 0.16% | −3,058−0.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 388,311 | $152.1M | 0.35% | −6,060−1.5% | Reduced |
| Arrowstreet Capital, Limited Partnership | 381,195 | $149.3M | 0.09% | +319,725+520.1% | Added |
| Robeco Institutional Asset Management B.V. | 379,371 | $148.6M | 0.22% | +49,980+15.2% | Added |
| Bank Julius Baer & Co. Ltd, Zurich | 376,495 | $147.5M | 0.42% | −14,881−3.8% | Reduced |
| Man Group plc | 362,774 | $142.1M | 0.27% | +235,156+184.3% | Added |
| Nordea Investment Management AB | 361,085 | $140.1M | 0.12% | +336,573+1,373.1% | Added |
| Russell Investments Group, Ltd. | 341,048 | $133.7M | 0.15% | +27,326+8.7% | Added |
| Public Employees Retirement Association of Colorado | 336,091 | $131.6M | 0.48% | −56,452−14.4% | Reduced |
| ProShare Advisors LLC | 333,732 | $130.7M | 0.27% | −67,512−16.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 319,467 | $125.1M | 0.21% | +5,786+1.8% | Added |
| B. Metzler seel. Sohn & Co. AG | 315,422 | $123.5M | 1.09% | −4,199−1.3% | Reduced |
| Standard Life Aberdeen plc | 314,889 | $123.3M | 0.20% | +26,922+9.3% | Added |
| Ensign Peak Advisors, Inc | 311,998 | $122.2M | 0.20% | +134,964+76.2% | Added |
| New York State Common Retirement Fund | 308,577 | $120.9M | 0.16% | −31,695−9.3% | Reduced |
| Royal London Asset Management Ltd | 277,196 | $108.6M | 0.23% | −6,149−2.2% | Reduced |
| Great West Life Assurance Co | 274,136 | $108.3M | 0.16% | +3,424+1.3% | Added |
| Alyeska Investment Group, L.P. | 267,169 | $104.6M | 0.32% | +202,169+311.0% | Added |
| LPL Financial LLC | 264,182 | $103.5M | 0.03% | +23,566+9.8% | Added |
| Cerity Partners LLC | 258,808 | $101.4M | 0.16% | −4,884−1.9% | Reduced |
| BNP Paribas Arbitrage, SA | 254,343 | $99.6M | 0.08% | −276,845−52.1% | Reduced |
| Swedbank AB | 254,096 | $99.5M | 0.10% | −251−0.1% | Reduced |
| Jane Street Group, LLC | 248,267 | $97.2M | 0.11% | +248,267 | New |
| National Bank of Canada | 247,941 | $97.1M | 0.11% | +7,563+3.1% | Added |
| Canada Pension Plan Investment Board | 246,364 | $96.5M | 0.07% | +78,956+47.2% | Added |
| State Board of Administration of Florida Retirement System | 233,612 | $91.5M | 0.16% | −17,399−6.9% | Reduced |
| Prudential Financial Inc | 225,814 | $88.4M | 0.11% | +45,578+25.3% | Added |
| Capital International Sarl | 225,734 | $88.4M | 1.53% | +2,345+1.0% | Added |
| Macquarie Group Ltd | 223,556 | $87.6M | 0.10% | −5,297−2.3% | Reduced |
| Caisse de Depot Et Placement du Quebec | 222,262 | $87.0M | 0.16% | +157,866+245.1% | Added |