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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,523
−13 vs. Q2 2025
Shares held
232.3M
−4.81M (−2.0%) vs. Q2 2025
Total value
$90.8B
−$14.7B (−14.0%) vs. Q2 2025
New holders
143
553 more added
Sold out
156
617 more reduced

28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 1,523 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ3 2025: $90.8B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding VRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Koesten, Hirschmann & Crabtree, INC.0$820.00%0Unchanged
Evolution Wealth Management Inc.1$3920.00%−39−97.5%Reduced
Dogwood Wealth Management LLC1$3920.00%−26−96.3%Reduced
Rialto Wealth Management, LLC1$3920.00%00.0%Unchanged
CGC Financial Services, LLC1$3920.00%00.0%Unchanged
ROSS\JOHNSON & Associates LLC1$3920.01%00.0%Unchanged
Turning Point Benefit Group, Inc.1$4040.00%+1New
Cornerstone Planning Group LLC117$5990.00%+2+1.7%Added
Delta Asset Management LLC2$7830.00%00.0%Unchanged
Logan Capital Management Inc2$7830.00%00.0%Unchanged
WFA of San Diego, LLC2$7830.00%00.0%Unchanged
HFM Investment Advisors, LLC2$7830.00%00.0%Unchanged
Davis Capital Management2$7830.00%+2New
Redwood Park Advisors LLC2$7840.00%−1−33.3%Reduced
Tradewinds Capital Management, LLC2$7840.00%00.0%Unchanged
West Branch Capital LLC2$7840.00%00.0%Unchanged
Seneschal Advisors, LLC2$7840.00%+2New
Navigoe, LLC5$1.00K0.00%+5New
Heritage Wealth Advisors3$1.18K0.00%−50−94.3%Reduced
Texas Capital Bancshares Inc3$1.18K0.00%+3New
Anfield Capital Management, LLC3$1.18K0.00%+3New
LGT Financial Advisors LLC4$1.57K0.00%00.0%Unchanged
Mowery & Schoenfeld Wealth Management, LLC4$1.57K0.00%00.0%Unchanged
S&T Bank4$1.57K0.00%+1+33.3%Added
Palisade Asset Management, LLC4$1.57K0.00%+4New
Hughes Financial Services, LLC4$1.69K0.00%−2−33.3%Reduced
PayPay Securities Corp5$1.92K0.07%+1+25.0%Added
Quest 10 Wealth Builders, Inc.5$1.93K0.00%+4+400.0%Added
Concord Wealth Partners5$1.96K0.00%−85−94.4%Reduced
American Capital Advisory, LLC5$1.96K0.00%00.0%Unchanged
Bernard Wealth Management Corp.5$1.96K0.00%00.0%Unchanged
Signature Resources Capital Management, LLC6$2.35K0.00%00.0%Unchanged
Louisbourg Investments Inc.6$2.35K0.00%00.0%Unchanged
Corsicana & Co.6$2.35K0.00%+6New
WestEnd Advisors, LLC7$2.74K0.00%−4−36.4%Reduced
Principia Wealth Advisory, LLC7$2.74K0.00%−3−30.0%Reduced
Bruce G. Allen Investments, LLC7$2.74K0.00%00.0%Unchanged
Maseco LLP7$2.74K0.00%00.0%Unchanged
Hara Capital LLC8$3.13K0.00%00.0%Unchanged
Granite FO LLC8$3.13K0.00%00.0%Unchanged
Reyes Financial Architecture, Inc.8$3.13K0.00%00.0%Unchanged
Frazier Financial Advisors, LLC8$3.13K0.00%00.0%Unchanged
Bay Harbor Wealth Management, LLC9$3.52K0.00%+2+28.6%Added
Hopwood Financial Services, Inc.9$3.52K0.00%00.0%Unchanged
Greykasell Wealth Strategies, Inc.9$3.52K0.00%+9New
Guerra Advisors Inc9$3.52K0.00%+9New
DecisionPoint Financial, LLC9$3.64K0.00%00.0%Unchanged
True Wealth Design, LLC10$3.73K0.00%−18−64.3%Reduced
Carolina Wealth Advisors, LLC10$3.92K0.00%−5−33.3%Reduced
C M Bidwell & Associates Ltd10$3.92K0.00%00.0%Unchanged
Minot DeBlois Advisors LLC10$3.92K0.00%00.0%Unchanged
HighMark Wealth Management LLC10$3.92K0.00%00.0%Unchanged
Piscataqua Savings Bank10$3.92K0.00%00.0%Unchanged
Strengthening Families & Communities, LLC10$3.92K0.00%00.0%Unchanged
Tortoise Investment Management, LLC10$3.92K0.00%+6+150.0%Added
First United Bank Trust10$3.92K0.00%+10New
Evergreen Private Wealth LLC10$3.92K0.00%+10New
Global Wealth Strategies & Associates11$4.31K0.00%00.0%Unchanged
Cherry Tree Wealth Management, LLC12$4.50K0.00%00.0%Unchanged
Essential Partners LLC12$4.70K0.00%−20−62.5%Reduced
Hartford Financial Management Inc.12$4.70K0.00%+2+20.0%Added
Security National Bank12$4.70K0.00%+12New
Coston, McIsaac & Partners14$5.00K0.00%00.0%Unchanged
Glen Eagle Advisors, LLC13$5.09K0.00%−6−31.6%Reduced
Longfellow Investment Management Co LLC13$5.09K0.00%+7+116.7%Added
Horizon Financial Services, LLC13$5.09K0.00%+11+550.0%Added
Hoey Investments, Inc13$5.09K0.00%00.0%Unchanged
Halbert Hargrove Global Advisors, LLC13$5.09K0.00%+13New
ZRC Wealth Management, LLC13$5.09K0.00%+13New
Motco14$5.48K0.00%−14−50.0%Reduced
Mascoma Wealth Management LLC14$5.48K0.00%00.0%Unchanged
WealthCollab, LLC14$5.48K0.00%00.0%Unchanged
Imprint Wealth LLC14$5.48K0.02%+14New
Kozak & Associates, Inc.13$5.64K0.00%00.0%Unchanged
Redmont Wealth Advisors LLC15$5.88K0.01%00.0%Unchanged
Clark Wealth Partners13$5.89K0.00%+13New
Activest Wealth Management16$6.13K0.00%−106−86.9%Reduced
CBIZ Investment Advisory Services, LLC16$6.27K0.00%−34−68.0%Reduced
Hollencrest Capital Management16$6.27K0.00%00.0%Unchanged
Cloud Capital Management, LLC18$7.00K0.00%+18New
Jackson, Grant Investment Advisers, Inc.18$7.05K0.00%00.0%Unchanged
IMG Wealth Management, Inc.18$7.05K0.00%00.0%Unchanged
Dunhill Financial, LLC19$7.34K0.00%−10−34.5%Reduced
FSA Wealth Management LLC19$7.44K0.00%00.0%Unchanged
Rakuten Securities, Inc.19$7.44K0.00%+1+5.6%Added
Missouri Trust & Investment Co20$7.83K0.00%−7−25.9%Reduced
Mendota Financial Group, LLC20$7.83K0.01%00.0%Unchanged
J.Safra Asset Management Corp20$7.83K0.00%+20New
Avion Wealth22$8.00K0.00%−9−29.0%Reduced
Penserra Capital Management LLC21$8.00K0.00%00.0%Unchanged
Y.D. More Investments Ltd89$8.11K0.00%+69+345.0%Added
Caldwell Sutter Capital, Inc.21$8.22K0.00%−1−4.5%Reduced
Aspect Partners, LLC21$8.22K0.00%−1−4.5%Reduced
Osterweis Capital Management Inc21$8.22K0.00%00.0%Unchanged
Cetera Trust Company, N.A21$8.22K0.00%00.0%Unchanged
Creative Financial Designs Inc21$8.22K0.00%+6+40.0%Added
Dynamic Wealth Strategies, LLC22$8.62K0.01%00.0%Unchanged
Westfuller Advisors, LLC23$8.91K0.00%+23New
DiNuzzo Private Wealth, Inc.23$8.99K0.00%−2−8.0%Reduced
LFA - Lugano Financial Advisors SA23$9.01K0.00%00.0%Unchanged