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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,442
+184 vs. Q3 2023
Shares held
235.9M
+594.5K (+0.3%) vs. Q3 2023
Total value
$95.7B
+$14.0B (+17.1%) vs. Q3 2023
New holders
245
560 more added
Sold out
61
480 more reduced

22 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 1,442 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2023: $95.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2023.

Institutions holding VRTX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc22,282,180$9.07B0.20%+298,824+1.4%Added
BlackRock Inc.21,881,203$8.90B0.23%−704,023−3.1%Reduced
Capital World Investors21,805,770$8.87B1.58%+3,824,103+21.3%Added
FMR LLC12,979,511$5.28B0.41%−1,380,926−9.6%Reduced
State Street Corp12,083,818$4.92B0.24%+44,272+0.4%Added
Alliancebernstein L.P.7,039,738$2.86B1.10%−486,718−6.5%Reduced
Price T Rowe Associates Inc5,887,412$2.40B0.32%−962,654−14.1%Reduced
Geode Capital Management, LLC5,673,419$2.30B0.24%+77,445+1.4%Added
JPMorgan Chase & Co5,624,265$2.29B0.23%−481,587−7.9%Reduced
Wellington Management Group LLP5,228,538$2.13B0.40%−1,297,313−19.9%Reduced
Jennison Associates LLC3,944,913$1.61B1.20%+147,248+3.9%Added
Massachusetts Financial Services Co3,625,802$1.48B0.48%−265,992−6.8%Reduced
Capital Research Global Investors3,567,664$1.45B0.36%+195,080+5.8%Added
Loomis Sayles & Co L P3,134,852$1.28B1.95%−28,616−0.9%Reduced
Norges Bank3,042,288$1.24B0.22%+368,382+13.8%Added
Morgan Stanley2,980,455$1.21B0.11%+110,354+3.8%Added
Amundi2,718,117$1.14B0.51%+774,696+39.9%Added
Northern Trust Corp2,680,597$1.09B0.20%−132,966−4.7%Reduced
UBS Asset Management Americas Inc2,599,904$1.06B0.42%−173,895−6.3%Reduced
Clearbridge Investments, LLC2,592,575$1.05B0.91%−350,609−11.9%Reduced
Ameriprise Financial Inc2,510,029$1.02B0.31%−427,783−14.6%Reduced
Bank of America Corp2,435,920$991.2M0.11%+82,919+3.5%Added
Janus Henderson Group PLC2,339,979$952.1M0.57%+681,156+41.1%Added
Invesco Ltd.2,242,107$912.3M0.22%+225,327+11.2%Added
Legal & General Group Plc2,061,605$838.8M0.26%+21,247+1.0%Added
Bank of New York Mellon Corp1,976,988$804.4M0.16%−36,908−1.8%Reduced
Deutsche Bank AG1,646,665$670.0M0.34%+320,297+24.1%Added
Renaissance Technologies LLC1,591,688$647.6M1.00%−72,400−4.4%Reduced
California Public Employees Retirement System1,515,816$616.8M0.47%+5,855+0.4%Added
Charles Schwab Investment Management Inc1,509,206$614.1M0.16%+41,778+2.8%Added
Goldman Sachs Group Inc1,484,934$604.2M0.13%−210,391−12.4%Reduced
Royal Bank of Canada1,454,472$591.8M0.15%+224,276+18.2%Added
Harding Loevner LP1,321,229$538.6M3.02%−25,522−1.9%Reduced
Pictet Asset Management Holding SA1,081,046$439.9M0.49%+22,231+2.1%Added
Winslow Capital Management, LLC925,369$376.5M1.56%−194,223−17.3%Reduced
Nuveen Asset Management, LLC841,123$342.2M0.11%+28,536+3.5%Added
Manufacturers Life Insurance Company, The818,803$333.2M0.20%−62,702−7.1%Reduced
Swiss National Bank807,100$328.4M0.24%−21,300−2.6%Reduced
Barclays PLC806,759$328.3M0.17%+550+0.1%Added
Caisse de Depot Et Placement du Quebec803,726$327.0M0.83%−12,298−1.5%Reduced
American Century Companies Inc800,537$325.7M0.22%−144,331−15.3%Reduced
Voya Investment Management LLC775,488$315.0M0.32%−83,547−9.7%Reduced
Wells Fargo & Company748,966$304.7M0.09%−31,321−4.0%Reduced
Bellevue Group AG736,390$299.6M4.58%−266,345−26.6%Reduced
First Trust Advisors LP734,835$299.0M0.33%−63,531−8.0%Reduced
Sumitomo Mitsui Trust Holdings, Inc.710,616$289.1M0.21%−968−0.1%Reduced
Franklin Resources Inc672,438$273.6M0.13%−82,086−10.9%Reduced
Swedbank AB664,034$270.2M0.44%−9,223−1.4%Reduced
Ensign Peak Advisors, Inc660,527$268.8M0.53%−94,975−12.6%Reduced
AQR Capital Management LLC644,768$262.3M0.49%+1,271+0.2%Added
Millennium Management LLC642,750$261.5M0.25%+97,421+17.9%Added
HSBC Holdings PLC614,669$250.2M0.23%+53,862+9.6%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.601,514$244.8M0.68%−88,634−12.8%Reduced
Dimensional Fund Advisors LP585,216$238.1M0.07%−7,179−1.2%Reduced
Standard Life Aberdeen plc581,018$236.4M0.51%+384,730+196.0%Added
Bank of Montreal574,127$235.2M0.13%+50,773+9.7%Added
Artisan Partners Limited Partnership576,507$234.6M0.37%−9,334−1.6%Reduced
TD Asset Management Inc533,913$217.2M0.21%+53,850+11.2%Added
DekaBank Deutsche Girozentrale503,978$205.8M0.42%+33,920+7.2%Added
Qube Research & Technologies Ltd465,025$189.2M0.43%+45,916+11.0%Added
Rhumbline Advisers458,488$186.6M0.20%−5,263−1.1%Reduced
Robeco Institutional Asset Management B.V.457,824$186.3M0.45%+24,887+5.7%Added
Citigroup Inc454,592$185.0M0.25%+8,995+2.0%Added
National Pension Service450,621$183.4M0.26%+9,128+2.1%Added
Zurcher Kantonalbank (Zurich Cantonalbank)445,187$181.1M0.69%+18,186+4.3%Added
Chevy Chase Trust Holdings, Inc.444,949$181.0M0.65%+14,311+3.3%Added
Victory Capital Management Inc435,838$177.3M0.19%−142,613−24.7%Reduced
Public Employees Retirement Association of Colorado434,874$176.9M0.82%−1,361−0.3%Reduced
UBS Group AG423,706$172.4M0.07%+71,008+20.1%Added
Allianz Asset Management GmbH419,787$170.8M0.32%−58,972−12.3%Reduced
California State Teachers Retirement System414,680$168.7M0.23%+5,787+1.4%Added
Envestnet Asset Management Inc412,629$167.9M0.07%+1,143+0.3%Added
New York State Common Retirement Fund409,026$166.4M0.23%−32,708−7.4%Reduced
Macquarie Group Ltd397,294$161.7M0.19%−333,639−45.6%Reduced
Neuberger Berman Group LLC395,780$161.0M0.14%+57,855+17.1%Added
BNP Paribas Arbitrage, SA392,394$159.7M0.29%+85,924+28.0%Added
Credit Suisse AG392,325$159.6M0.16%−103,643−20.9%Reduced
Los Angeles Capital Management LLC389,874$158.6M0.59%−37,196−8.7%Reduced
Royal London Asset Management Ltd387,803$157.8M0.45%−2,705−0.7%Reduced
Assetmark, Inc387,398$157.6M0.57%−117,030−23.2%Reduced
Principal Financial Group Inc368,728$150.0M0.10%+40,005+12.2%Added
SEI Investments Co359,354$146.2M0.23%−39,864−10.0%Reduced
Epoch Investment Partners, Inc.358,916$146.0M0.66%+10,059+2.9%Added
Canada Pension Plan Investment Board357,901$145.6M0.18%+9,077+2.6%Added
Man Group plc354,798$144.4M0.41%––
Raymond James & Associates342,417$139.3M0.10%+440.0%Added
Candriam Luxembourg S.C.A.342,086$139.2M0.96%−42,245−11.0%Reduced
Citadel Advisors LLC326,680$132.9M0.13%+298,936+1,077.5%Added
Nordea Investment Management AB321,331$131.2M0.17%+11,259+3.6%Added
Natixis Advisors, L.P.319,476$130.0M0.34%+266+0.1%Added
APG Asset Management N.V.342,694$126.2M0.25%+42,398+14.1%Added
Korea Investment CORP302,839$123.2M0.32%+22,498+8.0%Added
Adage Capital Partners GP, L.L.C.300,190$122.1M0.25%+186+0.1%Added
Mirae Asset Global Investments Co., Ltd.296,678$120.7M0.25%−21,922−6.9%Reduced
Assenagon Asset Management S.A.296,153$120.5M0.37%+93,922+46.4%Added
Russell Investments Group, Ltd.291,250$118.6M0.21%−65,369−18.3%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main290,715$118.3M0.16%+75,345+35.0%Added
State Board of Administration of Florida Retirement System287,550$117.0M0.24%−11,859−4.0%Reduced
Marshall Wace, LLP278,330$113.2M0.22%+72,715+35.4%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.275,415$113.1M0.20%+21,332+8.4%Added