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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 4 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital World Investors28,732,143$12.8B1.86%+198,835+0.7%Added
Vanguard Group Inc23,973,777$10.7B0.17%+482,616+2.1%Added
BlackRock, Inc.21,871,945$9.74B0.19%+89,012+0.4%Added
Capital Research Global Investors16,108,291$7.17B1.44%+1,571,947+10.8%Added
State Street Corp11,775,227$5.24B0.20%−13,430−0.1%Reduced
FMR LLC6,406,372$2.85B0.16%−1,320,812−17.1%Reduced
Jennison Associates LLC6,151,505$2.74B1.62%+1,089,063+21.5%Added
Geode Capital Management, LLC5,928,747$2.63B0.18%+166,987+2.9%Added
JPMorgan Chase & Co5,869,361$2.61B0.18%−1,886,284−24.3%Reduced
Wellington Management Group LLP4,813,386$2.14B0.39%−641,362−11.8%Reduced
Alliancebernstein L.P.4,378,320$1.95B0.64%+424,808+10.7%Added
Loomis Sayles & Co L P3,813,378$1.70B2.13%+65,047+1.7%Added
Norges Bank3,580,356$1.59B0.20%+216,206+6.4%Added
Morgan Stanley3,331,439$1.48B0.10%−77,081−2.3%Reduced
Price T Rowe Associates Inc3,159,870$1.41B0.16%+242,643+8.3%Added
UBS Asset Management Americas Inc3,067,473$1.37B0.28%+507,997+19.8%Added
Bank of America Corp2,807,617$1.25B0.10%−57,381−2.0%Reduced
Northern Trust Corp2,658,581$1.18B0.16%+39,189+1.5%Added
Capital International Investors2,635,903$1.17B0.20%+1,986,004+305.6%Added
Janus Henderson Group PLC2,619,534$1.17B0.57%−128,403−4.7%Reduced
Edgewood Management LLC2,454,947$1.09B3.47%−189,079−7.2%Reduced
Ameriprise Financial Inc2,181,362$971.1M0.24%−54,107−2.4%Reduced
Victory Capital Management Inc2,155,164$967.8M0.62%+1,861,279+633.3%Added
Invesco Ltd.1,984,046$883.3M0.15%+138,406+7.5%Added
Goldman Sachs Group Inc1,931,760$860.0M0.14%+197,166+11.4%Added
Legal & General Group Plc1,889,777$841.3M0.21%−4,392−0.2%Reduced
Charles Schwab Investment Management Inc1,773,625$789.6M0.14%+48,344+2.8%Added
Parnassus Investments1,711,440$761.9M1.76%−61,278−3.5%Reduced
Bank of New York Mellon Corp1,600,473$712.5M0.13%−111,192−6.5%Reduced
Clearbridge Investments, LLC1,527,864$680.2M0.55%−151,307−9.0%Reduced
Deutsche Bank AG1,407,634$626.7M0.23%+60,748+4.5%Added
Royal Bank of Canada1,384,368$616.3M0.12%+175,700+14.5%Added
Massachusetts Financial Services Co1,284,354$571.8M0.18%−740,554−36.6%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main1,205,796$536.8M0.56%+244,942+25.5%Added
Amundi1,133,226$517.9M0.18%−1,965,643−63.4%Reduced
WCM Investment Management, LLC1,163,670$513.5M1.17%+64,730+5.9%Added
Nuveen, LLC1,062,235$472.9M0.13%+63,817+6.4%Added
Renaissance Technologies LLC1,004,888$447.4M0.60%−166,683−14.2%Reduced
Barclays PLC822,937$366.4M0.15%−2,993−0.4%Reduced
Swiss National Bank778,300$346.5M0.21%+52,100+7.2%Added
Pictet Asset Management Holding SA735,822$327.0M0.33%+74,635+11.3%Added
California Public Employees Retirement System725,055$322.8M0.21%−84,179−10.4%Reduced
Harding Loevner LP711,611$316.8M2.13%+13,152+1.9%Added
Wells Fargo & Company702,052$312.6M0.07%−4,117−0.6%Reduced
UBS Group AG700,002$311.6M0.07%−37,416−5.1%Reduced
Voya Investment Management LLC699,644$310.9M0.31%−127,494−15.4%Reduced
Sumitomo Mitsui Trust Holdings, Inc.655,050$291.6M0.18%+11,063+1.7%Added
Artisan Partners Limited Partnership650,259$289.5M0.43%−68,872−9.6%Reduced
HSBC Holdings PLC641,961$285.7M0.18%−202,714−24.0%Reduced
Citigroup Inc599,079$266.7M0.19%−28,636−4.6%Reduced
Dimensional Fund Advisors LP596,227$265.4M0.06%−9,652−1.6%Reduced
Manufacturers Life Insurance Company, The546,956$243.5M0.22%+520.0%Added
Natixis Advisors, L.P.540,530$240.6M0.38%−60,657−10.1%Reduced
American Century Companies Inc538,132$239.6M0.13%+72,391+15.5%Added
BNP Paribas Arbitrage, SA531,188$236.5M0.18%−57,149−9.7%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.524,925$233.7M0.19%+35,858+7.3%Added
Franklin Resources Inc523,833$233.2M0.06%−178,201−25.4%Reduced
DekaBank Deutsche Girozentrale506,457$223.5M0.40%+15,328+3.1%Added
Raymond James Financial Inc499,777$222.5M0.08%−10,765−2.1%Reduced
National Pension Service497,800$221.6M0.19%−61,129−10.9%Reduced
Lazard Asset Management LLC480,310$213.8M0.29%−52,287−9.8%Reduced
TD Asset Management Inc465,173$207.1M0.18%−20,683−4.3%Reduced
Neuberger Berman Group LLC459,150$204.4M0.16%+16,522+3.7%Added
Rhumbline Advisers454,372$202.3M0.17%+3,341+0.7%Added
Envestnet Asset Management Inc448,988$199.9M0.06%−21,340−4.5%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.444,459$197.8M0.48%+52,446+13.4%Added
Bellevue Group AG441,610$196.6M4.33%+28,539+6.9%Added
Chevy Chase Trust Holdings, Inc.440,927$196.3M0.57%−2,121−0.5%Reduced
Principal Financial Group Inc409,805$182.4M0.10%−4,566−1.1%Reduced
ProShare Advisors LLC401,244$178.6M0.36%+18,214+4.8%Added
California State Teachers Retirement System397,640$177.0M0.20%−843−0.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)394,371$175.6M0.43%+9,661+2.5%Added
Public Employees Retirement Association of Colorado392,543$174.8M0.67%−25,577−6.1%Reduced
Bank Julius Baer & Co. Ltd, Zurich391,376$174.2M0.52%−6,655−1.7%Reduced
Bank of Montreal363,035$161.6M0.08%−50,652−12.2%Reduced
New York State Common Retirement Fund340,272$151.5M0.20%−5,524−1.6%Reduced
Robeco Institutional Asset Management B.V.329,391$146.6M0.24%+183,391+125.6%Added
B. Metzler seel. Sohn & Co. AG319,621$142.3M1.36%+5,278+1.7%Added
Universal- Beteiligungs- und Servicegesellschaft mbH313,681$139.7M0.25%+7,220+2.4%Added
Russell Investments Group, Ltd.313,722$139.6M0.18%−23,725−7.0%Reduced
SEI Investments Co297,403$132.4M0.15%+3,621+1.2%Added
Standard Life Aberdeen plc287,967$128.2M0.22%−16,747−5.5%Reduced
First Trust Advisors LP287,892$128.2M0.10%+143,084+98.8%Added
Royal London Asset Management Ltd283,345$126.1M0.29%−52,297−15.6%Reduced
Great West Life Assurance Co270,712$120.7M0.19%−120.0%Reduced
Cerity Partners LLC263,692$117.4M0.21%+10,768+4.3%Added
Swedbank AB254,347$113.2M0.13%+254,347New
State Board of Administration of Florida Retirement System251,011$111.8M0.20%+2,302+0.9%Added
Tredje AP-fonden250,602$111.6M0.89%+209,112+504.0%Added
Assenagon Asset Management S.A.242,754$108.1M0.17%+34,614+16.6%Added
LPL Financial LLC240,616$107.1M0.04%+23,672+10.9%Added
National Bank of Canada240,378$107.0M0.12%+99,751+70.9%Added
Manning & Napier Advisors LLC233,580$104.0M1.24%−1,528−0.6%Reduced
Macquarie Group Ltd228,853$101.9M0.13%−5,283−2.3%Reduced
Carmignac Gestion227,296$101.2M1.56%+100,342+79.0%Added
Davenport & Co LLC226,184$100.5M0.56%+874+0.4%Added
Capital International Sarl223,389$99.5M1.91%+37,218+20.0%Added
Mirae Asset Global ETFs Holdings Ltd.219,433$97.7M0.19%−17,792−7.5%Reduced
Welch & Forbes LLC217,244$96.7M1.21%+9,605+4.6%Added
Handelsbanken Fonder AB214,293$95.4M0.34%+6,648+3.2%Added