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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,128
+33 vs. Q2 2022
Shares held
237.2M
+1.97M (+0.8%) vs. Q2 2022
Total value
$68.5B
+$2.47B (+3.7%) vs. Q2 2022
New holders
113
434 more added
Sold out
80
409 more reduced

15 institutions that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 1,128 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ3 2022: $68.5B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2022.

Institutions holding VRTX in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.25,243,060$7.31B0.25%+105,908+0.4%Added
Vanguard Group Inc21,132,336$6.12B0.18%+293,861+1.4%Added
FMR LLC17,366,023$5.03B0.52%+613,012+3.7%Added
Capital World Investors12,524,679$3.63B0.81%−45,253−0.4%Reduced
State Street Corp12,294,791$3.56B0.23%+30,742+0.3%Added
Alliancebernstein L.P.9,145,516$2.65B1.28%−154,714−1.7%Reduced
Wellington Management Group LLP8,029,342$2.32B0.50%−206,297−2.5%Reduced
Geode Capital Management, LLC5,271,667$1.52B0.23%+737,183+16.3%Added
Price T Rowe Associates Inc5,157,954$1.49B0.25%+195,271+3.9%Added
JPMorgan Chase & Co4,859,687$1.41B0.22%−377,855−7.2%Reduced
Jennison Associates LLC4,755,821$1.38B1.37%+2,983,253+168.3%Added
Massachusetts Financial Services Co4,346,731$1.26B0.47%+4,619+0.1%Added
Loomis Sayles & Co L P4,158,390$1.20B2.44%−299,346−6.7%Reduced
Ameriprise Financial Inc4,041,993$1.17B0.43%−520,956−11.4%Reduced
Clearbridge Investments, LLC3,900,856$1.13B1.14%−342,408−8.1%Reduced
UBS Asset Management Americas Inc3,158,692$914.6M0.51%+36,378+1.2%Added
Northern Trust Corp2,887,998$836.2M0.19%−48,936−1.7%Reduced
Bank of America Corp2,527,455$731.8M0.10%−169,343−6.3%Reduced
Norges Bank2,288,472$662.6M0.18%+61,874+2.8%Added
Renaissance Technologies LLC2,138,885$619.3M0.88%+377,717+21.4%Added
Legal & General Group Plc2,138,098$619.1M0.24%−62,651−2.8%Reduced
Bank of New York Mellon Corp2,081,470$602.7M0.15%−16,831−0.8%Reduced
Morgan Stanley1,937,545$561.0M0.08%+110,320+6.0%Added
Amundi1,825,322$551.3M0.33%+893,935+96.0%Added
Deutsche Bank AG1,827,457$529.1M0.32%−213,715−10.5%Reduced
California Public Employees Retirement System1,799,868$521.1M0.48%−77,220−4.1%Reduced
Goldman Sachs Group Inc1,720,747$498.2M0.15%+673,107+64.2%Added
Harding Loevner LP1,639,817$474.8M3.11%−93,874−5.4%Reduced
Canada Pension Plan Investment Board1,605,854$465.0M0.79%−43,120−2.6%Reduced
Janus Henderson Group PLC1,501,535$434.8M0.33%−137,417−8.4%Reduced
Charles Schwab Investment Management Inc1,387,940$401.9M0.14%+23,848+1.7%Added
Nuveen Asset Management, LLC1,334,841$386.5M0.16%+82,937+6.6%Added
Invesco Ltd.1,319,682$382.1M0.12%+196,888+17.5%Added
American Century Companies Inc1,260,097$364.8M0.32%+80,563+6.8%Added
Bellevue Group AG1,158,126$335.3M4.81%−18,010−1.5%Reduced
Swiss National Bank1,108,375$320.9M0.23%+4,100+0.4%Added
Caisse de Depot Et Placement du Quebec1,085,220$314.2M0.94%−193,874−15.2%Reduced
Voya Investment Management LLC948,821$274.7M0.33%+698,774+279.5%Added
Sumitomo Mitsui Trust Holdings, Inc.936,055$271.0M0.22%+7,748+0.8%Added
Franklin Resources Inc932,851$270.1M0.15%−58,108−5.9%Reduced
Royal Bank of Canada923,240$267.3M0.09%+38,005+4.3%Added
Macquarie Group Ltd897,308$259.8M0.32%−35,871−3.8%Reduced
Allianz Asset Management GmbH880,754$255.0M0.58%−321,150−26.7%Reduced
Dimensional Fund Advisors LP864,307$250.3M0.10%−17,338−2.0%Reduced
Pictet Asset Management SA782,783$226.6M0.34%+59,632+8.2%Added
Wells Fargo & Company778,271$225.3M0.08%−21,431−2.7%Reduced
Manufacturers Life Insurance Company, The751,883$218.3M0.15%+2,088+0.3%Added
Prudential Financial Inc718,922$208.2M0.35%+13,296+1.9%Added
Impax Asset Management Group plc697,733$201.6M1.04%−23,201−3.2%Reduced
Assenagon Asset Management S.A.662,235$191.7M0.82%+146,237+28.3%Added
Swedbank AB632,514$183.1M0.44%−49,384−7.2%Reduced
Lazard Asset Management LLC623,841$180.6M0.26%−240,065−27.8%Reduced
Credit Suisse AG575,559$166.6M0.19%−150,896−20.8%Reduced
Lord, Abbett & Co. LLC554,586$160.6M0.59%+21,734+4.1%Added
APG Asset Management N.V.521,289$154.1M0.40%−299,066−36.5%Reduced
Fred Alger Management, LLC527,706$152.8M0.77%+29,367+5.9%Added
Victory Capital Management Inc523,524$151.6M0.18%−25,868−4.7%Reduced
Avidity Partners Management LP512,800$148.5M3.23%−280,200−35.3%Reduced
Natixis Advisors, L.P.508,420$147.2M0.62%−95,775−15.9%Reduced
Vaughan Nelson Investment Management, L.P.504,261$146.0M2.11%−357,332−41.5%Reduced
AQR Capital Management LLC494,531$143.2M0.35%−22,253−4.3%Reduced
Candriam Luxembourg S.C.A.484,539$140.3M0.99%+16,656+3.6%Added
Citigroup Inc483,241$139.9M0.20%+365+0.1%Added
Allspring Global Investments Holdings, LLC477,201$138.2M0.24%+95,856+25.1%Added
New York State Common Retirement Fund470,490$136.2M0.20%−20,242−4.1%Reduced
Epoch Investment Partners, Inc.454,964$131.7M0.86%−46,972−9.4%Reduced
Public Employees Retirement Association of Colorado452,718$131.1M0.76%+2,161+0.5%Added
Eaton Vance Management451,027$130.6M0.19%+1,336+0.3%Added
TD Asset Management Inc439,595$128.7M0.16%−1,946−0.4%Reduced
Los Angeles Capital Management LLC434,526$125.8M0.65%+97,060+28.8%Added
California State Teachers Retirement System430,019$124.5M0.21%−3,382−0.8%Reduced
DekaBank Deutsche Girozentrale422,718$123.0M0.36%−49,786−10.5%Reduced
Barclays PLC412,900$119.5M0.13%+31,812+8.3%Added
National Pension Service405,860$118.8M0.25%+3,493+0.9%Added
Rhumbline Advisers408,183$118.2M0.18%+12,188+3.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.401,906$116.4M0.46%−115,213−22.3%Reduced
Ensign Peak Advisors, Inc395,691$114.6M0.28%+30,810+8.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)394,559$114.2M0.68%+33,449+9.3%Added
Assetmark, Inc387,858$112.3M0.53%+380,279+5,017.5%Added
OrbiMed Advisors LLC373,200$108.1M2.15%−14,000−3.6%Reduced
Raymond James & Associates363,730$105.3M0.11%+3,113+0.9%Added
First Trust Advisors LP360,892$104.5M0.14%−668,540−64.9%Reduced
Handelsbanken Fonder AB356,817$103.3M0.69%+6,361+1.8%Added
Principal Financial Group Inc356,158$103.1M0.08%+39,731+12.6%Added
Korea Investment CORP356,014$103.1M0.32%+51,315+16.8%Added
Skandinaviska Enskilda Banken AB (publ)351,711$101.8M0.82%+98,458+38.9%Added
Robeco Institutional Asset Management B.V.339,030$98.2M0.32%+85,003+33.5%Added
Adage Capital Partners GP, L.L.C.337,163$97.6M0.24%−234,867−41.1%Reduced
Russell Investments Group, Ltd.324,112$94.0M0.21%+21,966+7.3%Added
Mirae Asset Global Investments Co., Ltd.319,967$92.7M0.25%−15,755−4.7%Reduced
Nomura Asset Management Co Ltd319,179$92.4M0.59%+6,227+2.0%Added
DnB Asset Management AS315,982$91.5M0.71%−29,221−8.5%Reduced
New York State Teachers Retirement System315,110$91.2M0.24%−8,158−2.5%Reduced
HSBC Holdings PLC311,868$90.9M0.16%−18,892−5.7%Reduced
Tekla Capital Management LLC313,403$90.7M3.71%−47,828−13.2%Reduced
State Board of Administration of Florida Retirement System311,075$90.1M0.23%−4,400−1.4%Reduced
Retirement Systems of Alabama297,783$86.2M0.40%−93,575−23.9%Reduced
Great West Life Assurance Co298,238$86.2M0.25%−1,219−0.4%Reduced
Pendal Group Limited297,298$86.1M0.84%−61,498−17.1%Reduced
Polar Capital Holdings Plc290,280$84.0M0.68%−10,000−3.3%Reduced