Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Connor, Clark & Lunn Investment Management Ltd. | 220,801 | $86.5M | 0.27% | +14,706+7.1% | Added |
| Welch & Forbes LLC | 220,346 | $86.3M | 1.04% | +3,102+1.4% | Added |
| Davenport & Co LLC | 217,284 | $85.3M | 0.46% | −8,900−3.9% | Reduced |
| TD Asset Management Inc | 217,539 | $85.2M | 0.07% | −247,634−53.2% | Reduced |
| Handelsbanken Fonder AB | 214,760 | $84.1M | 0.27% | +467+0.2% | Added |
| New York State Teachers Retirement System | 212,829 | $83.4M | 0.16% | +9,325+4.6% | Added |
| Baillie Gifford & Co | 207,056 | $81.1M | 0.06% | −5,423−2.6% | Reduced |
| Korea Investment CORP | 205,745 | $80.6M | 0.17% | +4,011+2.0% | Added |
| Aviva PLC | 204,889 | $80.2M | 0.15% | +12,229+6.3% | Added |
| Capital International Inc | 191,341 | $74.9M | 0.60% | +16,108+9.2% | Added |
| First Trust Advisors LP | 188,161 | $73.7M | 0.05% | −99,731−34.6% | Reduced |
| Carmignac Gestion | 187,539 | $73.5M | 1.09% | −39,757−17.5% | Reduced |
| Federated Hermes, Inc. | 186,569 | $73.1M | 0.13% | −7,390−3.8% | Reduced |
| Tredje AP-fonden | 185,312 | $72.6M | 0.58% | −65,290−26.1% | Reduced |
| SEI Investments Co | 176,527 | $69.1M | 0.07% | −120,876−40.6% | Reduced |
| Candriam Luxembourg S.C.A. | 174,567 | $68.4M | 0.36% | −1,831−1.0% | Reduced |
| Citadel Advisors LLC | 173,502 | $68.0M | 0.05% | +144,675+501.9% | Added |
| APG Asset Management N.V. | 200,588 | $66.9M | 0.19% | −1,364−0.7% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 165,945 | $65.0M | 0.10% | −53,488−24.4% | Reduced |
| Danske Bank A/S | 164,480 | $64.4M | 0.16% | −42,266−20.4% | Reduced |
| AXA Investment Managers S.A. | 163,680 | $64.1M | 0.17% | +163,680 | New |
| AQR Capital Management LLC | 161,683 | $63.3M | 0.04% | +20,147+14.2% | Added |
| Congress Asset Management Co | 160,875 | $63.0M | 0.42% | −27,129−14.4% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 154,248 | $60.4M | 0.24% | −22,356−12.7% | Reduced |
| Birch Hill Investment Advisors LLC | 153,602 | $60.2M | 2.54% | +5,288+3.6% | Added |
| Provident Investment Management, Inc. | 153,406 | $60.1M | 5.30% | −5,301−3.3% | Reduced |
| Woodline Partners LP | 153,272 | $60.0M | 0.28% | +61,608+67.2% | Added |
| Mirae Asset Global Investments Co., Ltd. | 151,056 | $59.2M | 0.19% | +6,468+4.5% | Added |
| Quadrature Capital Ltd | 149,908 | $58.7M | 0.69% | +131,995+736.9% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 149,855 | $58.7M | 0.13% | −498−0.3% | Reduced |
| Van Eck Associates Corp | 149,056 | $58.4M | 0.05% | +8,355+5.9% | Added |
| State of Wisconsin Investment Board | 148,349 | $58.1M | 0.13% | +5,411+3.8% | Added |
| Asset Management One Co.,Ltd. | 146,864 | $57.5M | 0.17% | +5,303+3.7% | Added |
| Lansforsakringar Fondforvaltning AB (publ) | 146,563 | $57.4M | 0.30% | +5,273+3.7% | Added |
| Truist Financial Corp | 143,864 | $56.3M | 0.08% | −66,225−31.5% | Reduced |
| Stifel Financial Corp | 142,529 | $55.8M | 0.05% | +40,984+40.4% | Added |
| ABN AMRO Bank N.V. | 141,871 | $55.4M | 0.54% | +8,799+6.6% | Added |
| Intermede Investment Partners Ltd | 140,023 | $54.8M | 2.25% | −53,892−27.8% | Reduced |
| Colony Group, LLC | 139,215 | $54.5M | 0.09% | −3,894−2.7% | Reduced |
| KBC Group NV | 133,602 | $52.3M | 0.13% | +937+0.7% | Added |
| British Columbia Investment Management Corp | 131,847 | $51.6M | 0.30% | −34,603−20.8% | Reduced |
| Allspring Global Investments Holdings, LLC | 126,863 | $51.3M | 0.08% | +323+0.3% | Added |
| Abn Amro Investment Solutions | 125,960 | $49.3M | 1.01% | −4,331−3.3% | Reduced |
| Bowen Hanes & Co Inc | 124,434 | $48.7M | 1.22% | −56,365−31.2% | Reduced |
| Schroder Investment Management Group | 121,587 | $48.1M | 0.04% | −13,380−9.9% | Reduced |
| Capital International Ltd | 121,287 | $47.5M | 1.72% | −6,320−5.0% | Reduced |
| Teacher Retirement System of Texas | 118,648 | $46.5M | 0.19% | −3,725−3.0% | Reduced |
| Sofinnova Investments, Inc. | 117,875 | $46.2M | 2.83% | +117,875 | New |
| Treasurer of the State of North Carolina | 115,629 | $45.3M | 0.14% | −4,505−3.7% | Reduced |
| Raiffeisen Bank International AG | 112,591 | $44.5M | 0.59% | −1,336−1.2% | Reduced |
| NEOS Investment Management LLC | 113,533 | $44.5M | 0.33% | +37,296+48.9% | Added |
| Nomura Asset Management Co Ltd | 112,333 | $44.0M | 0.11% | −46,583−29.3% | Reduced |
| Storebrand Asset Management AS | 111,868 | $43.8M | 0.12% | +3,585+3.3% | Added |
| Vontobel Holding Ltd. | 110,642 | $43.3M | 0.14% | +38,844+54.1% | Added |
| Freestone Grove Partners LP | 110,283 | $43.2M | 0.32% | +110,283 | New |
| Mariner, LLC | 110,251 | $43.2M | 0.06% | −8,872−7.4% | Reduced |
| Allianz Asset Management GmbH | 110,161 | $43.1M | 0.05% | −6,036−5.2% | Reduced |
| Voloridge Investment Management, LLC | 105,502 | $41.3M | 0.14% | +105,502 | New |
| Toronto Dominion Bank | 104,878 | $41.1M | 0.08% | −13,748−11.6% | Reduced |
| Guggenheim Capital LLC | 103,125 | $40.4M | 0.30% | +1,905+1.9% | Added |
| Public Employees Retirement System of Ohio | 102,732 | $40.2M | 0.13% | −3,323−3.1% | Reduced |
| CI Private Wealth, LLC | 101,731 | $39.9M | 0.06% | −1,085−1.1% | Reduced |
| Country Trust Bank | 98,532 | $38.6M | 0.84% | +8,396+9.3% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 98,153 | $38.4M | 0.29% | +4,464+4.8% | Added |
| DnB Asset Management AS | 95,414 | $37.4M | 0.14% | +8,483+9.8% | Added |
| Creative Planning | 94,864 | $37.2M | 0.03% | +7,690+8.8% | Added |
| Rockefeller Capital Management L.P. | 92,814 | $36.3M | 0.07% | −6,924−6.9% | Reduced |
| KLP Kapitalforvaltning AS | 92,641 | $36.3M | 0.14% | −200−0.2% | Reduced |
| Resona Asset Management Co.,Ltd. | 92,098 | $36.1M | 0.17% | −4,351−4.5% | Reduced |
| State of New Jersey Common Pension Fund D | 90,129 | $35.3M | 0.13% | +3,400+3.9% | Added |
| Assetmark, Inc | 89,850 | $35.2M | 0.08% | −2,541−2.8% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 89,622 | $35.1M | 0.30% | −1,466−1.6% | Reduced |
| State of Tennessee, Treasury Department | 86,761 | $34.0M | 0.11% | −18,998−18.0% | Reduced |
| Bank of Nova Scotia | 86,252 | $33.8M | 0.06% | +36,643+73.9% | Added |
| Advisor Group Holdings, Inc. | 84,250 | $33.0M | 0.05% | +33,922+67.4% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 83,846 | $32.8M | 0.06% | −14,715−14.9% | Reduced |
| Rafferty Asset Management, LLC | 81,128 | $31.8M | 0.10% | +6,020+8.0% | Added |
| CIBC Asset Management Inc | 81,005 | $31.7M | 0.09% | +190.0% | Added |
| STRS Ohio | 80,625 | $31.6M | 0.12% | −32,133−28.5% | Reduced |
| Kovitz Investment Group Partners, LLC | 80,587 | $31.6M | 0.12% | +48,544+151.5% | Added |
| Tang Capital Management LLC | 80,000 | $31.3M | 1.21% | +70,000+700.0% | Added |
| Banco Santander, S.A. | 79,406 | $31.1M | 0.28% | +9,218+13.1% | Added |
| Hardman Johnston Global Advisors LLC | 79,152 | $31.0M | 1.52% | −29,073−26.9% | Reduced |
| Thrivent Financial for Lutherans | 78,270 | $30.7M | 0.06% | −9,932−11.3% | Reduced |
| Cetera Investment Advisers | 77,714 | $30.4M | 0.04% | +17,518+29.1% | Added |
| Janney Montgomery Scott LLC | 77,456 | $30.3M | 0.07% | +5,566+7.7% | Added |
| Wealth Enhancement Advisory Services, LLC | 73,469 | $30.1M | 0.05% | −9,172−11.1% | Reduced |
| Beacon Investment Advisory Services, Inc. | 76,142 | $29.8M | 1.25% | −889−1.2% | Reduced |
| MetLife Investment Management | 75,807 | $29.7M | 0.14% | −1,341−1.7% | Reduced |
| Migdal Insurance & Financial Holdings Ltd. | 75,000 | $29.4M | 0.32% | +75,000 | New |
| Arizona State Retirement System | 74,994 | $29.4M | 0.16% | −100−0.1% | Reduced |
| State of Michigan Retirement System | 72,023 | $28.2M | 0.14% | −500−0.7% | Reduced |
| Motley Fool Wealth Management, LLC | 71,349 | $27.9M | 1.89% | +17,436+32.3% | Added |
| The PNC Financial Services Group, Inc. | 69,772 | $27.3M | 0.02% | −6,384−8.4% | Reduced |
| Trillium Asset Management, LLC | 68,385 | $26.8M | 0.71% | +6,911+11.2% | Added |
| Nomura Holdings Inc | 68,254 | $26.7M | 0.12% | +66,650+4,155.2% | Added |
| Erste Asset Management GmbH | 67,517 | $26.7M | 0.26% | −6,386−8.6% | Reduced |
| Comerica Bank | 68,025 | $26.6M | 0.10% | +3,350+5.2% | Added |
| Susquehanna International Group, LLP | 67,683 | $26.5M | 0.04% | +5,474+8.8% | Added |
| Daiwa Securities Group Inc. | 67,227 | $26.3M | 0.09% | −8,605−11.3% | Reduced |