Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nissay Asset Management Corp | 66,657 | $26.1M | 0.14% | +1,019+1.6% | Added |
| Pacer Advisors, Inc. | 66,501 | $26.0M | 0.07% | +26,543+66.4% | Added |
| Gateway Investment Advisers LLC | 65,926 | $25.8M | 0.25% | +132+0.2% | Added |
| Jupiter Asset Management Ltd | 65,619 | $25.7M | 0.22% | +65,619 | New |
| Czech National Bank | 65,118 | $25.5M | 0.18% | +2,348+3.7% | Added |
| Swiss Life Asset Management Ltd | 63,945 | $25.0M | 0.13% | +6,045+10.4% | Added |
| GF Fund Management Co. Ltd. | 62,791 | $24.6M | 0.45% | +474+0.8% | Added |
| Xponance, Inc. | 62,491 | $24.5M | 0.19% | −109−0.2% | Reduced |
| AMF Pensionsforsakring AB | 62,462 | $24.5M | 0.16% | −2,243−3.5% | Reduced |
| Davidson Investment Advisors | 62,421 | $24.4M | 1.04% | −1,268−2.0% | Reduced |
| Credit Agricole S A | 62,387 | $24.4M | 0.08% | +62,387 | New |
| Rakuten Investment Management, Inc. | 242,462 | $24.1M | 0.09% | +242,462 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 61,569 | $24.1M | 0.12% | −1,412−2.2% | Reduced |
| Foster Dykema Cabot & Partners, LLC | 60,689 | $23.8M | 1.56% | −234−0.4% | Reduced |
| SG Americas Securities, LLC | 60,062 | $23.5M | 0.09% | −55,578−48.1% | Reduced |
| Commonwealth Equity Services, LLC | 58,285 | $22.8M | 0.03% | −1,113−1.9% | Reduced |
| Zacks Investment Management | 58,026 | $22.7M | 0.18% | +3,710+6.8% | Added |
| Moody Lynn & Lieberson, LLC | 56,559 | $22.2M | 1.19% | −1,518−2.6% | Reduced |
| Amalgamated Bank | 56,514 | $22.1M | 0.16% | +779+1.4% | Added |
| AIA Group Ltd | 56,054 | $22.0M | 0.39% | +11,570+26.0% | Added |
| Nisa Investment Advisors, LLC | 55,778 | $21.8M | 0.08% | −9,639−14.7% | Reduced |
| Harvest Fund Management Co., Ltd | 50,671 | $21.8M | 0.92% | +1,156+2.3% | Added |
| Quantinno Capital Management LP | 55,641 | $21.8M | 0.06% | +9,319+20.1% | Added |
| Reynders McVeigh Capital Management, LLC | 55,350 | $21.7M | 1.02% | +1,040+1.9% | Added |
| Atwood & Palmer Inc | 55,297 | $21.7M | 1.27% | +105+0.2% | Added |
| Edgemoor Investment Advisors, Inc. | 55,194 | $21.6M | 1.67% | −830−1.5% | Reduced |
| Hemenway Trust Co LLC | 55,125 | $21.6M | 1.65% | −390−0.7% | Reduced |
| Artia Global Partners LP | 55,100 | $21.6M | 3.80% | +50,700+1,152.3% | Added |
| Forsta Ap-Fonden | 55,000 | $21.5M | 0.13% | +3,000+5.8% | Added |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 54,994 | $21.5M | 0.17% | +6,904+14.4% | Added |
| Retirement Systems of Alabama | 54,693 | $21.4M | 0.07% | −409−0.7% | Reduced |
| Mackenzie Financial Corp | 54,343 | $21.3M | 0.03% | +18,068+49.8% | Added |
| Lido Advisors, LLC | 53,695 | $21.0M | 0.09% | +7,873+17.2% | Added |
| Illinois Municipal Retirement Fund | 52,801 | $20.7M | 0.26% | −823−1.5% | Reduced |
| Cullinan Associates Inc | 51,412 | $20.1M | 1.31% | −600−1.2% | Reduced |
| Qube Research & Technologies Ltd | 51,382 | $20.1M | 0.03% | +45,701+804.5% | Added |
| Tudor Investment Corp Et Al | 51,374 | $20.1M | 0.13% | +51,374 | New |
| Hallmark Capital Management Inc | 49,819 | $19.5M | 1.29% | +1,130+2.3% | Added |
| Smith Group Asset Management, LLC | 48,857 | $19.1M | 1.10% | +2,602+5.6% | Added |
| IFM Investors Pty Ltd | 49,484 | $19.1M | 0.17% | −833−1.7% | Reduced |
| Rhenman & Partners Asset Management AB | 46,955 | $18.4M | 2.03% | −14,500−23.6% | Reduced |
| Sanctuary Advisors, LLC | 46,253 | $18.1M | 0.10% | −917−1.9% | Reduced |
| C WorldWide Group Holding A/S | 46,057 | $18.0M | 0.28% | 00.0% | Unchanged |
| Marshall Wace, LLP | 45,885 | $18.0M | 0.02% | −71,115−60.8% | Reduced |
| Calamos Advisors LLC | 45,753 | $17.9M | 0.07% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 45,315 | $17.7M | 0.11% | −4,931−9.8% | Reduced |
| China Universal Asset Management Co., Ltd. | 45,114 | $17.7M | 1.46% | +849+1.9% | Added |
| CIBC Bancorp USA Inc. | 44,774 | $17.5M | 0.11% | +44,774 | New |
| La Banque Postale Asset Management SA | 44,279 | $17.3M | 0.21% | +4,938+12.6% | Added |
| USS Investment Management Ltd | 44,099 | $17.3M | 0.08% | −55−0.1% | Reduced |
| HighTower Advisors, LLC | 44,015 | $17.2M | 0.02% | −12,332−21.9% | Reduced |
| W.G. Shaheen & Associates DBA Whitney & Co | 43,556 | $17.1M | 1.55% | −253−0.6% | Reduced |
| Groupama Asset Managment | 43,381 | $17.0M | 0.25% | −17,916−29.2% | Reduced |
| Citizens Financial Group Inc | 42,881 | $16.8M | 0.23% | +9,963+30.3% | Added |
| Teachers Retirement System of the State of Kentucky | 42,581 | $16.7M | 0.13% | −25,599−37.5% | Reduced |
| Utah Retirement Systems | 42,499 | $16.6M | 0.16% | −34−0.1% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 41,376 | $16.2M | 0.13% | +2,341+6.0% | Added |
| Millennium Management LLC | 41,042 | $16.1M | 0.01% | +41,042 | New |
| Gradient Investments LLC | 40,977 | $16.0M | 0.27% | +2,964+7.8% | Added |
| Segall Bryant & Hamill, LLC | 40,971 | $16.0M | 0.21% | −1,357−3.2% | Reduced |
| Boston Common Asset Management, LLC | 40,899 | $16.0M | 0.45% | −5,164−11.2% | Reduced |
| Armistice Capital, LLC | 40,239 | $15.8M | 0.49% | +40,239 | New |
| Aristotle Atlantic Partners, LLC | 39,804 | $15.6M | 0.45% | −5,572−12.3% | Reduced |
| Tweedy, Browne Co LLC | 39,065 | $15.3M | 1.33% | +1,812+4.9% | Added |
| Ilmarinen Mutual Pension Insurance Co | 38,800 | $15.2M | 0.11% | −6,000−13.4% | Reduced |
| Bridgewater Associates, LP | 38,324 | $15.0M | 0.06% | +3,934+11.4% | Added |
| Pathstone Holdings, LLC | 37,879 | $14.8M | 0.06% | +1,446+4.0% | Added |
| New York Life Investment Management LLC | 37,432 | $14.7M | 0.13% | −1,468−3.8% | Reduced |
| Wealthfront Advisers LLC | 37,373 | $14.6M | 0.03% | −6,545−14.9% | Reduced |
| Virginia Retirement Systems Et Al | 37,100 | $14.5M | 0.09% | +37,100 | New |
| JustInvest LLC | 37,000 | $14.5M | 0.15% | −1,491−3.9% | Reduced |
| Shelton Capital Management | 36,679 | $14.4M | 0.31% | −16,336−30.8% | Reduced |
| Martingale Asset Management L P | 36,522 | $14.3M | 0.36% | −4,760−11.5% | Reduced |
| Cornerstone Advisors, LLC | 36,100 | $14.1M | 0.47% | −500−1.4% | Reduced |
| Andra AP-fonden | 35,900 | $14.1M | 0.18% | +35,900 | New |
| State of Alaska, Department of Revenue | 35,853 | $14.0M | 0.14% | −9,402−20.8% | Reduced |
| iA Global Asset Management Inc. | 35,842 | $14.0M | 0.19% | +685+1.9% | Added |
| O'Shaughnessy Asset Management, LLC | 35,681 | $14.0M | 0.08% | +1,422+4.2% | Added |
| Los Angeles Capital Management LLC | 35,472 | $13.9M | 0.05% | +2,458+7.4% | Added |
| Vestcor Inc | 35,266 | $13.8M | 0.41% | +3,778+12.0% | Added |
| Adams Diversified Equity Fund, Inc. | 35,100 | $13.7M | 0.46% | 00.0% | Unchanged |
| Varma Mutual Pension Insurance Co | 34,926 | $13.7M | 0.09% | −1,700−4.6% | Reduced |
| Foster Victor Wealth Advisors, LLC | 33,857 | $13.7M | 0.85% | +8,493+33.5% | Added |
| Flputnam Investment Management Co | 34,676 | $13.6M | 0.20% | −3,065−8.1% | Reduced |
| Bailard, Inc. | 34,639 | $13.6M | 0.29% | −3,508−9.2% | Reduced |
| Sapient Capital LLC | 34,311 | $13.6M | 0.21% | −1,999−5.5% | Reduced |
| Intech Investment Management LLC | 34,361 | $13.5M | 0.12% | +16,873+96.5% | Added |
| MML Investors Services, LLC | 34,231 | $13.4M | 0.04% | −2,376−6.5% | Reduced |
| Elo Mutual Pension Insurance Co | 33,783 | $13.2M | 0.22% | +491+1.5% | Added |
| Oddo BHF Asset Management SAS | 33,278 | $13.0M | 0.50% | +20,890+168.6% | Added |
| McRae Capital Management Inc | 33,159 | $13.0M | 2.58% | +2,706+8.9% | Added |
| Galvin, Gaustad & Stein, LLC | 33,142 | $13.0M | 1.06% | +10,252+44.8% | Added |
| Barlow Wealth Partners, Inc. | 29,880 | $12.7M | 1.42% | −21,078−41.4% | Reduced |
| Louisiana State Employees Retirement System | 32,200 | $12.6M | 0.21% | −100−0.3% | Reduced |
| US Bancorp | 30,856 | $12.1M | 0.01% | −2,727−8.1% | Reduced |
| Liontrust Investment Partners LLP | 30,300 | $11.9M | 0.17% | +3,346+12.4% | Added |
| Headlands Technologies LLC | 29,864 | $11.7M | 0.93% | +29,864 | New |
| Washington Trust Bank | 29,809 | $11.7M | 0.86% | +566+1.9% | Added |
| Natixis | 29,806 | $11.7M | 0.06% | −1,155−3.7% | Reduced |
| Aquatic Capital Management LLC | 29,596 | $11.6M | 0.22% | +29,596 | New |