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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Aviva PLC222,452$99.3M0.17%+6,241+2.9%Added
Handelsbanken Fonder AB220,847$98.6M0.33%+4,516+2.1%Added
Manning & Napier Advisors LLC220,589$98.5M1.39%−207,014−48.4%Reduced
Welch & Forbes LLC219,669$98.1M1.27%+1,471+0.7%Added
Ensign Peak Advisors, Inc215,165$96.1M0.18%−88,619−29.2%Reduced
Lazard Asset Management LLC213,131$95.2M0.16%+14,181+7.1%Added
New York State Teachers Retirement System211,336$94.4M0.19%+244+0.1%Added
Davenport & Co LLC210,152$93.7M0.52%−1,425−0.7%Reduced
Capital International Sarl208,882$93.3M1.53%+15,444+8.0%Added
Agf Management Ltd201,403$89.9M0.40%+200,835+35,358.3%Added
Korea Investment CORP201,168$89.8M0.19%+7,733+4.0%Added
Baillie Gifford & Co199,421$89.0M0.09%−1,667−0.8%Reduced
Jones Financial Companies LLLP202,860$87.9M0.04%+194,865+2,437.3%Added
Great West Life Assurance Co192,144$86.1M0.15%+4,540+2.4%Added
Canada Pension Plan Investment Board190,051$84.9M0.05%−12,282−6.1%Reduced
Mirae Asset Global Investments Co., Ltd.188,064$84.0M0.24%+13,717+7.9%Added
NEOS Investment Management LLC174,087$77.7M0.39%+27,889+19.1%Added
Mirae Asset Global ETFs Holdings Ltd.171,925$76.6M0.10%+1,150+0.7%Added
AQR Capital Management LLC171,031$76.0M0.03%+27,380+19.1%Added
Mitsubishi UFJ Trust & Banking Corp166,903$74.5M0.18%+4,697+2.9%Added
Lord, Abbett & Co. LLC166,509$74.4M0.24%+166,509New
APG Asset Management N.V.191,385$74.2M0.24%+3,000+1.6%Added
Groupama Asset Managment165,897$74.1M1.08%+2,753+1.7%Added
Schroder Investment Management Group163,898$72.6M0.06%+40,646+33.0%Added
Capital International Inc161,723$72.2M0.56%+2,063+1.3%Added
Stifel Financial Corp161,052$71.9M0.07%+8,605+5.6%Added
Nomura Asset Management International Inc.156,484$69.9M0.12%−21,881−12.3%Reduced
Danske Bank A/S153,006$68.3M0.16%−4,159−2.6%Reduced
Birch Hill Investment Advisors LLC150,795$67.3M3.02%−1,690−1.1%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund149,962$67.0M0.37%+60,900+68.4%Added
Rockefeller Capital Management L.P.149,655$66.8M0.12%+14,423+10.7%Added
Carmignac Gestion148,199$66.2M1.02%−43,372−22.6%Reduced
Provident Investment Management, Inc.147,620$65.9M6.55%−1,638−1.1%Reduced
Van Eck Associates Corp146,116$65.2M0.05%−3,335−2.2%Reduced
Asset Management One Co.,Ltd.141,949$63.4M0.19%−8,157−5.4%Reduced
SEB Asset Management AB140,951$62.9M0.27%+140,951New
State of Wisconsin Investment Board136,548$61.0M0.14%−1,361−1.0%Reduced
Bowen Hanes & Co Inc135,399$60.5M1.47%+1,895+1.4%Added
PFA Pension, Forsikringsaktieselskab134,996$60.3M0.18%−192−0.1%Reduced
Woodline Partners LP134,954$60.3M0.23%+7,228+5.7%Added
SEI Investments Co133,226$59.5M0.05%−230,797−63.4%Reduced
Mariner, LLC131,600$58.8M0.07%+3,135+2.4%Added
Prudential Financial Inc131,560$58.7M0.07%−3,059−2.3%Reduced
Colony Group, LLC131,435$58.7M0.07%−1,411−1.1%Reduced
Tri Locum Partners LP129,314$57.7M8.10%+129,314New
KBC Group NV127,208$56.8M0.14%−13,912−9.9%Reduced
Quantinno Capital Management LP126,604$56.5M0.09%+34,320+37.2%Added
Vanguard Investments Australia, Ltd.126,261$56.4M0.16%+126,261New
Teacher Retirement System of Texas124,317$55.5M0.23%+13,307+12.0%Added
Allspring Global Investments Holdings, LLC123,760$55.4M0.09%+1,550+1.3%Added
Jane Street Group, LLC122,946$54.9M0.06%+111,700+993.2%Added
Capital Fund Management S.A.122,934$54.9M0.49%+122,934New
Credit Agricole S A122,365$54.6M0.18%+75,471+160.9%Added
Nomura Asset Management Co Ltd121,167$54.1M0.14%+1,469+1.2%Added
ABN AMRO Bank N.V.118,349$53.3M0.57%−36,872−23.8%Reduced
Truist Financial Corp114,449$51.1M0.07%−11,744−9.3%Reduced
Creative Planning109,524$48.9M0.03%+9,011+9.0%Added
Treasurer of the State of North Carolina108,663$48.5M0.15%+905+0.8%Added
Jones Hill Capital LP108,603$48.5M10.40%+108,603New
Healthcare of Ontario Pension Plan Trust Fund108,251$48.3M0.08%+20,523+23.4%Added
DnB Asset Management AS107,311$47.9M0.17%−12,374−10.3%Reduced
CIBC Asset Management Inc106,893$47.7M0.12%−748−0.7%Reduced
Intermede Investment Partners Ltd106,370$47.5M2.20%−27,008−20.2%Reduced
Country Trust Bank105,075$46.9M0.89%+4,482+4.5%Added
Public Employees Retirement System of Ohio102,985$46.0M0.15%+322+0.3%Added
Storebrand Asset Management AS102,567$45.8M0.13%−7,006−6.4%Reduced
Raiffeisen Bank International AG101,435$45.0M0.65%−11,210−10.0%Reduced
Guggenheim Capital LLC100,386$44.8M0.36%−655−0.6%Reduced
Banco Santander, S.A.99,388$44.4M0.36%+1,361+1.4%Added
La Banque Postale Asset Management SA98,975$44.2M0.60%+31,778+47.3%Added
Mackenzie Financial Corp96,709$43.2M0.05%+33,410+52.8%Added
Capital International Ltd95,874$42.8M1.59%+262+0.3%Added
KLP Kapitalforvaltning AS95,381$42.6M0.17%+2,480+2.7%Added
Virginia Retirement Systems Et Al94,060$42.0M0.31%+56,960+153.5%Added
Toroso Investments, LLC92,081$41.0M0.13%+75,243+446.9%Added
Erste Asset Management GmbH91,958$40.8M0.38%+24,595+36.5%Added
Kovitz Investment Group Partners, LLC90,885$40.6M0.94%−7,490−7.6%Reduced
Resona Asset Management Co.,Ltd.90,312$40.3M0.20%+913+1.0%Added
Pacer Advisors, Inc.88,863$39.7M0.11%+12,721+16.7%Added
Fifth Third Bancorp88,499$39.5M0.07%+66,341+299.4%Added
State of New Jersey Common Pension Fund D86,710$38.7M0.15%−1,125−1.3%Reduced
CI Private Wealth, LLC86,492$38.2M0.05%−16,078−15.7%Reduced
Janney Montgomery Scott LLC84,324$37.7M0.09%+13,971+19.9%Added
Lansforsakringar Fondforvaltning AB (publ)83,846$37.4M0.20%−7,980−8.7%Reduced
Vontobel Holding Ltd.83,380$37.2M0.13%−21,907−20.8%Reduced
Swiss Life Asset Management Ltd82,574$36.9M0.18%+9,556+13.1%Added
State of Tennessee, Treasury Department81,668$36.5M0.12%+1,295+1.6%Added
Eurizon Capital SGR S.p.A.81,509$36.4M0.11%+4,115+5.3%Added
Toronto Dominion Bank78,472$35.0M0.07%−12,816−14.0%Reduced
Calamos Advisors LLC77,886$34.8M0.13%+33,917+77.1%Added
Thrivent Financial for Lutherans75,977$33.9M0.06%−710−0.9%Reduced
STRS Ohio74,163$33.1M0.13%−4,115−5.3%Reduced
Tredje AP-fonden73,799$33.0M0.18%−57,928−44.0%Reduced
Cetera Investment Advisers72,633$32.4M0.03%−2,380−3.2%Reduced
The PNC Financial Services Group, Inc.71,942$32.1M0.02%+2,517+3.6%Added
Federated Hermes, Inc.71,822$32.1M0.05%−5,839−7.5%Reduced
Nissay Asset Management Corp71,463$31.9M0.17%+1,836+2.6%Added
MetLife Investment Management70,804$31.6M0.16%−2,477−3.4%Reduced
Xponance, Inc.70,714$31.6M0.22%+4,941+7.5%Added
Arizona State Retirement System69,515$31.0M0.18%−2,778−3.8%Reduced