Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,698
- +51 vs. Q4 2025
- Shares held
- 237.8M
- +23.8M (+11.1%) vs. Q4 2025
- Total value
- $106.1B
- +$9.16B (+9.4%) vs. Q4 2025
- New holders
- 155
- 683 more added
- Sold out
- 104
- 600 more reduced
24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Czech National Bank | 69,176 | $30.9M | 0.20% | +2,274+3.4% | Added |
| State of Michigan Retirement System | 69,123 | $30.9M | 0.16% | −100−0.1% | Reduced |
| Abn Amro Investment Solutions | 68,216 | $30.5M | 0.40% | +49,146+257.7% | Added |
| Holocene Advisors, LP | 67,618 | $30.2M | 0.07% | +66,140+4,475.0% | Added |
| Daiwa Securities Group Inc. | 67,539 | $30.2M | 0.09% | −3,056−4.3% | Reduced |
| Gateway Investment Advisers LLC | 67,121 | $30.0M | 0.33% | +1,013+1.5% | Added |
| HighTower Advisors, LLC | 65,684 | $29.3M | 0.03% | +18,125+38.1% | Added |
| ING Groep NV | 65,425 | $29.2M | 0.18% | −15,704−19.4% | Reduced |
| Los Angeles Capital Management LLC | 64,937 | $29.0M | 0.11% | −228,364−77.9% | Reduced |
| GF Fund Management Co. Ltd. | 64,591 | $28.8M | 0.48% | −820−1.3% | Reduced |
| CIBC Bancorp USA Inc. | 63,952 | $28.6M | 0.04% | +63,952 | New |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 63,822 | $28.5M | 0.23% | +1,061+1.7% | Added |
| Trillium Asset Management, LLC | 99,762 | $28.1M | 0.93% | +37,069+59.1% | Added |
| O'Shaughnessy Asset Management, LLC | 61,867 | $27.6M | 0.14% | +14,622+30.9% | Added |
| Ofi Invest Asset Management | 69,233 | $26.8M | 0.35% | +109+0.2% | Added |
| Assetmark, Inc | 59,954 | $26.8M | 0.05% | −30,529−33.7% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 59,167 | $26.4M | 0.13% | +151+0.3% | Added |
| Hardman Johnston Global Advisors LLC | 58,357 | $26.1M | 1.24% | −5,449−8.5% | Reduced |
| Nisa Investment Advisors, LLC | 58,183 | $26.0M | 0.10% | +1,589+2.8% | Added |
| Foster Dykema Cabot & Partners, LLC | 57,792 | $25.8M | 1.64% | −552−0.9% | Reduced |
| Moody Lynn & Lieberson, LLC | 57,640 | $25.7M | 1.44% | +2,648+4.8% | Added |
| SG Americas Securities, LLC | 56,982 | $25.4M | 0.03% | −58,917−50.8% | Reduced |
| Beacon Investment Advisory Services, Inc. | 56,104 | $25.1M | 1.04% | −17,989−24.3% | Reduced |
| Atwood & Palmer Inc | 55,753 | $24.9M | 1.40% | +361+0.7% | Added |
| Smith Group Asset Management, LLC | 55,746 | $24.9M | 1.27% | +3,695+7.1% | Added |
| Edgemoor Investment Advisors, Inc. | 55,415 | $24.7M | 1.95% | +576+1.1% | Added |
| Pinebridge Investments LLC | 55,100 | $24.6M | 0.21% | +52,199+1,799.3% | Added |
| Zacks Investment Management | 55,082 | $24.6M | 0.20% | −1,544−2.7% | Reduced |
| Commonwealth Equity Services, LLC | 54,972 | $24.5M | 0.03% | +829+1.5% | Added |
| Reynders McVeigh Capital Management, LLC | 54,664 | $24.4M | 1.23% | +759+1.4% | Added |
| Rafferty Asset Management, LLC | 54,572 | $24.4M | 0.10% | −13,510−19.8% | Reduced |
| Retirement Systems of Alabama | 53,938 | $24.1M | 0.08% | −38−0.1% | Reduced |
| Amalgamated Bank | 53,269 | $23.8M | 0.18% | −1,851−3.4% | Reduced |
| Rakuten Investment Management, Inc. | 52,690 | $23.4M | 0.05% | +5,505+11.7% | Added |
| Cullinan Associates Inc | 51,762 | $23.1M | 1.87% | +450+0.9% | Added |
| Hemenway Trust Co LLC | 51,499 | $23.0M | 1.85% | +482+0.9% | Added |
| Davidson Investment Advisors | 51,222 | $22.9M | 0.99% | −13,005−20.2% | Reduced |
| IFM Investors Pty Ltd | 51,070 | $22.8M | 0.19% | +1,290+2.6% | Added |
| Caisse de Depot Et Placement du Quebec | 50,917 | $22.7M | 0.04% | −62,851−55.2% | Reduced |
| Hallmark Capital Management Inc | 50,139 | $22.4M | 1.44% | −812−1.6% | Reduced |
| Citizens Financial Group Inc | 49,824 | $22.2M | 0.31% | +6,421+14.8% | Added |
| BI Asset Management Fondsmaeglerselskab A/S | 49,531 | $22.1M | 0.23% | +39,005+370.6% | Added |
| Sanctuary Advisors, LLC | 49,360 | $22.0M | 0.12% | −444−0.9% | Reduced |
| PensionDanmark Pensionsforsikringsaktieselskab | 49,204 | $22.0M | 0.21% | −177−0.4% | Reduced |
| Natixis | 48,192 | $21.5M | 0.09% | −12,026−20.0% | Reduced |
| USS Investment Management Ltd | 47,128 | $21.0M | 0.09% | +1,735+3.8% | Added |
| Wealthfront Advisers LLC | 46,395 | $20.7M | 0.05% | +3,226+7.5% | Added |
| C WorldWide Group Holding A/S | 46,057 | $20.6M | 0.44% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 46,000 | $20.5M | 0.47% | −128,466−73.6% | Reduced |
| Hudson Bay Capital Management LP | 45,000 | $20.1M | 0.12% | −119,518−72.6% | Reduced |
| Martingale Asset Management L P | 44,750 | $20.0M | 0.50% | +1,529+3.5% | Added |
| Zurich Insurance Group Ltd | 44,618 | $19.9M | 0.16% | −4,081−8.4% | Reduced |
| Pathstone Holdings, LLC | 44,262 | $19.8M | 0.08% | −1,342−2.9% | Reduced |
| W.G. Shaheen & Associates DBA Whitney & Co | 44,117 | $19.7M | 1.64% | −47−0.1% | Reduced |
| Advisor Group Holdings, Inc. | 43,972 | $19.6M | 0.03% | +220+0.5% | Added |
| China Universal Asset Management Co., Ltd. | 43,902 | $19.6M | 1.48% | −4,145−8.6% | Reduced |
| Varma Mutual Pension Insurance Co | 43,626 | $19.5M | 0.11% | +3,000+7.4% | Added |
| Lido Advisors, LLC | 43,511 | $19.4M | 0.08% | −10,086−18.8% | Reduced |
| Rhenman & Partners Asset Management AB | 43,485 | $19.4M | 2.40% | +9,230+26.9% | Added |
| Motley Fool Wealth Management, LLC | 42,836 | $19.1M | 2.16% | −16,701−28.1% | Reduced |
| Empowered Funds, LLC | 41,737 | $18.6M | 0.12% | +26,931+181.9% | Added |
| Gradient Investments LLC | 41,736 | $18.6M | 0.29% | −1,859−4.3% | Reduced |
| JustInvest LLC | 41,623 | $18.6M | 0.18% | +2,458+6.3% | Added |
| Utah Retirement Systems | 41,265 | $18.4M | 0.19% | −1,225−2.9% | Reduced |
| Public Sector Pension Investment Board | 41,177 | $18.4M | 0.06% | +8,326+25.3% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 40,778 | $18.1M | 0.13% | −53,059−56.5% | Reduced |
| Illinois Municipal Retirement Fund | 40,573 | $18.1M | 0.23% | −6,213−13.3% | Reduced |
| Tweedy, Browne Co LLC | 40,387 | $18.0M | 1.43% | +1,239+3.2% | Added |
| Macquarie Group Ltd | 40,236 | $18.0M | 0.11% | −4,500−10.1% | Reduced |
| Balyasny Asset Management LLC | 40,137 | $17.9M | 0.04% | −73,351−64.6% | Reduced |
| Integral Health Asset Management, LLC | 40,000 | $17.9M | 0.95% | +40,000 | New |
| William Blair Investment Management, LLC | 39,547 | $17.7M | 0.06% | −188−0.5% | Reduced |
| Flputnam Investment Management Co | 39,498 | $17.6M | 0.26% | +2,707+7.4% | Added |
| Ossiam | 39,357 | $17.6M | 0.31% | +21,763+123.7% | Added |
| Police & Firemen's Retirement System of New Jersey | 39,061 | $17.4M | 0.15% | −412−1.0% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 40,668 | $17.4M | 0.04% | −40,578−49.9% | Reduced |
| Apollon Wealth Management, LLC | 38,595 | $17.2M | 0.28% | +9,400+32.2% | Added |
| Segall Bryant & Hamill, LLC | 38,073 | $17.0M | 0.24% | −1,746−4.4% | Reduced |
| New York Life Investment Management LLC | 38,069 | $17.0M | 0.14% | +1,251+3.4% | Added |
| Bailard, Inc. | 37,862 | $16.9M | 0.39% | +3,887+11.4% | Added |
| Aristotle Atlantic Partners, LLC | 37,532 | $16.8M | 0.78% | −859−2.2% | Reduced |
| Teachers Retirement System of the State of Kentucky | 36,725 | $16.4M | 0.13% | −3,598−8.9% | Reduced |
| Shelton Capital Management | 36,379 | $16.2M | 0.36% | −862−2.3% | Reduced |
| Caxton Associates LLP | 36,026 | $16.1M | 0.37% | +36,026 | New |
| Y-Intercept (Hong Kong) Ltd | 35,829 | $16.0M | 0.30% | +35,829 | New |
| Bank of Nova Scotia | 35,361 | $15.8M | 0.03% | −62,559−63.9% | Reduced |
| Galvin, Gaustad & Stein, LLC | 35,233 | $15.7M | 1.26% | +924+2.7% | Added |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 34,991 | $15.6M | 0.55% | +3,710+11.9% | Added |
| British Columbia Investment Management Corp | 34,971 | $15.6M | 0.09% | −10,525−23.1% | Reduced |
| Allianz Asset Management GmbH | 34,339 | $15.3M | 0.02% | −1,937−5.3% | Reduced |
| McRae Capital Management Inc | 34,123 | $15.2M | 3.16% | −1,435−4.0% | Reduced |
| Vestcor Inc | 34,019 | $15.2M | 0.42% | −2,671−7.3% | Reduced |
| Ilmarinen Mutual Pension Insurance Co | 33,800 | $15.1M | 0.12% | −5,000−12.9% | Reduced |
| MML Investors Services, LLC | 33,419 | $14.9M | 0.04% | −4,585−12.1% | Reduced |
| State of Alaska, Department of Revenue | 33,180 | $14.8M | 0.16% | +265+0.8% | Added |
| Captrust Financial Advisors | 32,092 | $14.3M | 0.03% | +18,288+132.5% | Added |
| Elo Mutual Pension Insurance Co | 31,378 | $14.0M | 0.23% | −235−0.7% | Reduced |
| Fisher Asset Management, LLC | 31,158 | $13.9M | 0.00% | +5,940+23.6% | Added |
| iA Global Asset Management Inc. | 30,915 | $13.8M | 0.20% | −6,770−18.0% | Reduced |
| Millennium Management LLC | 30,823 | $13.8M | 0.01% | −334,841−91.6% | Reduced |