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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,698
+51 vs. Q4 2025
Shares held
237.8M
+23.8M (+11.1%) vs. Q4 2025
Total value
$106.1B
+$9.16B (+9.4%) vs. Q4 2025
New holders
155
683 more added
Sold out
104
600 more reduced

24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1,698 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2026: $106.1B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.

Institutions holding VRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Walleye Capital LLC30,752$13.7M0.08%+15,778+105.4%Added
Foster Victor Wealth Advisors, LLC30,754$13.7M0.78%−2,175−6.6%Reduced
Barlow Wealth Partners, Inc.30,411$13.4M1.49%+324+1.1%Added
CAPROCK Group, Inc.30,007$13.4M0.33%+984+3.4%Added
US Bancorp29,781$13.3M0.02%−69−0.2%Reduced
Americana Partners, LLC29,773$13.3M0.35%+2,640+9.7%Added
Louisiana State Employees Retirement System29,600$13.2M0.23%−400−1.3%Reduced
Osmosis Investment Management UK Ltd29,580$13.2M0.35%−10,714−26.6%Reduced
AIA Group Ltd29,522$13.2M0.19%−4,299−12.7%Reduced
Susquehanna Portfolio Strategies, LLC29,189$13.0M0.19%00.0%Unchanged
Huntington National Bank29,123$13.0M0.07%−3,876−11.7%Reduced
Oregon Public Employees Retirement Fund29,083$13.0M0.17%+39+0.1%Added
Massmutual Trust Co FSB28,726$12.8M0.35%+812+2.9%Added
Banque Pictet & Cie SA28,550$12.7M0.15%+4,222+17.4%Added
CIBC World Markets Inc.28,078$12.5M0.02%+19,945+245.2%Added
Avanza Fonder AB27,647$12.3M0.34%+62+0.2%Added
Shelter Mutual Insurance Co27,600$12.3M2.74%00.0%Unchanged
Madison Asset Management, LLC27,387$12.2M0.15%+10,952+66.6%Added
Atria Investments LLC27,342$12.2M0.14%−919−3.3%Reduced
Bogart Wealth, LLC27,196$12.1M0.47%+19+0.1%Added
Ieq Capital, LLC27,175$12.1M0.06%+4,651+20.6%Added
Mutual of America Capital Management LLC26,967$12.0M0.14%−230−0.8%Reduced
Nordea Investment Management AB27,171$12.0M0.01%−419,998−93.9%Reduced
HRT Financial LP26,790$12.0M0.03%+26,790New
ASR Vermogensbeheer N.V.26,691$11.9M0.14%+632+2.4%Added
Fagan Associates, Inc.26,553$11.9M1.65%−130.0%Reduced
OP Asset Management Ltd26,189$11.7M0.12%−2,263−8.0%Reduced
Bender Robert & Associates26,171$11.7M2.80%−292−1.1%Reduced
Danica Pension, Livsforsikringsaktieselskab26,126$11.7M0.22%+26,126New
Nomura Holdings Inc26,101$11.7M0.10%−21,761−45.5%Reduced
CCM Investment Advisers LLC25,894$11.6M1.11%−355−1.4%Reduced
Acadian Asset Management LLC25,868$11.5M0.02%+3,658+16.5%Added
LVM Capital Management Ltd25,830$11.5M1.09%+55+0.2%Added
Biondo Investment Advisors, LLC25,315$11.3M1.45%+175+0.7%Added
Norinchukin Bank, The25,049$11.2M0.13%+846+3.5%Added
HealthInvest Partners AB22,984$11.2M3.61%00.0%Unchanged
Longaeva Partners L.P.24,935$11.1M0.54%+24,935New
Washington Trust Bank24,923$11.1M0.82%−4,916−16.5%Reduced
Horizon Investments, LLC24,435$10.9M0.12%+13,060+114.8%Added
Advisors Asset Management, Inc.24,300$10.9M0.18%−413−1.7%Reduced
Allianz SE23,921$10.7M0.12%−1,260−5.0%Reduced
Andra AP-fonden23,903$10.7M0.13%−12,037−33.5%Reduced
Jefferies Financial Group Inc.23,810$10.6M0.13%−7,562−24.1%Reduced
Heirloom Wealth Management23,458$10.5M1.89%+3,259+16.1%Added
Wiley Bros.-Aintree Capital, LLC23,387$10.5M0.05%+1,249+5.6%Added
Yousif Capital Management, LLC23,367$10.4M0.12%−937−3.9%Reduced
Telos Capital Management, Inc.23,234$10.4M0.99%+858+3.8%Added
Profund Advisors LLC23,137$10.3M0.38%−5,681−19.7%Reduced
Warren Averett Asset Management, LLC23,055$10.3M0.08%+323+1.4%Added
Kennedy Capital Management, Inc.22,994$10.3M0.22%+580+2.6%Added
Mercer Global Advisors Inc22,762$10.2M0.02%−1,060−4.4%Reduced
Cary Street Partners Financial LLC22,467$10.0M0.25%+112+0.5%Added
ExodusPoint Capital Management, LP22,403$10.0M0.10%+22,403New
Grandfield & Dodd, LLC21,704$9.69M0.55%+473+2.2%Added
FIL Ltd21,623$9.66M0.01%+11,820+120.6%Added
Exencial Wealth Advisors, LLC21,598$9.64M0.30%−784−3.5%Reduced
Pinnacle Associates Ltd21,590$9.64M0.12%−3,648−14.5%Reduced
Allstate Corp21,523$9.61M0.10%+2,428+12.7%Added
Eurizon SLJ Capital Ltd21,523$9.54M4.54%−2,633−10.9%Reduced
Capital Group Investment Management Pte. Ltd.21,084$9.41M1.61%+219+1.0%Added
Diversify Wealth Management, LLC22,232$9.41M0.17%+10,542+90.2%Added
EULAV Asset Management21,000$9.38M0.30%−1,000−4.5%Reduced
Camden National Bank20,907$9.34M1.26%−61−0.3%Reduced
Gotham Asset Management, LLC20,887$9.33M0.03%−624−2.9%Reduced
Modera Wealth Management, LLC20,685$9.24M0.11%−590−2.8%Reduced
GW Henssler & Associates Ltd20,640$9.22M0.43%+1,806+9.6%Added
Motley Fool Asset Management LLC20,302$9.07M0.39%−3,301−14.0%Reduced
Susquehanna International Group, LLP20,221$9.03M0.01%−63,875−76.0%Reduced
AIMZ Investment Advisors, LLC19,956$8.91M2.75%−305−1.5%Reduced
QRG Capital Management, Inc.19,900$8.89M0.09%+1,504+8.2%Added
Fiduciary Trust Co19,876$8.88M0.10%−156−0.8%Reduced
LMR Partners LLP19,853$8.87M0.08%+3,385+20.6%Added
Intech Investment Management LLC19,713$8.80M0.09%−8,817−30.9%Reduced
UniSuper Management Pty Ltd19,658$8.78M0.06%−334−1.7%Reduced
Gulf International Bank (UK) Ltd19,636$8.77M0.20%+6,720+52.0%Added
Investment Management Corp of Ontario19,562$8.74M0.11%−2,738−12.3%Reduced
Harvest Fund Management Co., Ltd19,486$8.70M0.37%−34,712−64.0%Reduced
Pinnacle Financial Partners, Inc.19,226$8.59M0.07%+638+3.4%Added
Capital Group Private Client Services, Inc.19,226$8.59M0.14%−4,626−19.4%Reduced
Sapient Capital LLC18,992$8.48M0.13%−15,332−44.7%Reduced
Omers Administration Corp18,797$8.39M0.05%+3,318+21.4%Added
Azimuth Capital Investment Management LLC18,656$8.33M0.31%−86−0.5%Reduced
Broderick Brian C18,656$8.33M1.54%+1,454+8.5%Added
Ethic Inc.17,896$7.99M0.13%+1,913+12.0%Added
Beacon Pointe Advisors, LLC17,894$7.99M0.04%+4,392+32.5%Added
Steward Partners Investment Advisory, LLC17,863$7.98M0.04%+499+2.9%Added
Hantz Financial Services, Inc.17,807$7.95M0.12%+10,616+147.6%Added
Sig Brokerage, LP17,605$7.86M2.22%−3,259−15.6%Reduced
Prudential PLC17,526$7.83M0.06%+1,755+11.1%Added
Strategic Planning Group, LLC17,389$7.77M1.09%+17,389New
Oppenheimer Asset Management Inc.17,302$7.73M0.09%+582+3.5%Added
Bleakley Financial Group, LLC17,226$7.69M0.12%+1,632+10.5%Added
Boston Common Asset Management, LLC17,205$7.68M0.49%+1,124+7.0%Added
GWM Advisors LLC17,146$7.66M0.03%−189−1.1%Reduced
Third View Private Wealth, LLC16,901$7.55M1.03%+1,184+7.5%Added
Capitolis Liquid Global Markets LLC16,806$7.50M0.05%+16,806New
Trifecta Capital Advisors, LLC16,757$7.48M1.16%+260+1.6%Added
Somerville Kurt F16,735$7.47M1.97%−6,592−28.3%Reduced
Cullen/Frost Bankers, Inc.16,568$7.40M0.08%+15,978+2,708.1%Added
Blair William & Co16,541$7.39M0.02%+451+2.8%Added