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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Welch & Forbes LLC221,304$109.9M1.34%+1,635+0.7%Added
State Board of Administration of Florida Retirement System219,813$109.2M0.18%−4,842−2.2%Reduced
Handelsbanken Fonder AB218,292$108.4M0.31%−2,555−1.2%Reduced
Korea Investment CORP213,312$106.0M0.20%+12,144+6.0%Added
Jones Financial Companies LLLP215,419$105.8M0.04%+12,559+6.2%Added
Capital International Sarl210,718$104.7M1.48%+1,836+0.9%Added
Standard Life Aberdeen plc210,601$104.6M0.15%−22,879−9.8%Reduced
Ensign Peak Advisors, Inc210,483$104.6M0.17%−4,682−2.2%Reduced
Mirae Asset Global Investments Co., Ltd.210,209$104.4M0.20%+22,145+11.8%Added
Agf Management Ltd207,971$103.3M0.40%+6,568+3.3%Added
TD Asset Management Inc207,960$103.3M0.09%−20,235−8.9%Reduced
Davenport & Co LLC207,108$103.0M0.53%−3,044−1.4%Reduced
New York State Teachers Retirement System206,935$102.8M0.19%−4,401−2.1%Reduced
APG Asset Management N.V.234,624$101.9M0.25%+43,239+22.6%Added
Nykredit A/S204,386$101.5M0.39%+204,386New
Tri Locum Partners LP201,791$100.2M12.33%+72,477+56.0%Added
Candriam Luxembourg S.C.A.199,505$99.0M0.45%−29,410−12.8%Reduced
NEOS Investment Management LLC193,306$96.0M0.35%+19,219+11.0%Added
Groupama Asset Managment188,156$93.9M1.18%+22,259+13.4%Added
Great West Life Assurance Co182,365$90.4M0.14%−9,779−5.1%Reduced
Healthcare of Ontario Pension Plan Trust Fund177,679$88.3M0.13%+69,428+64.1%Added
Mitsubishi UFJ Trust & Banking Corp174,812$86.8M0.19%+7,909+4.7%Added
National Bank of Canada172,898$85.9M0.08%−99,219−36.5%Reduced
Schroder Investment Management Group169,270$84.6M0.06%+5,372+3.3%Added
CIBC Bancorp USA Inc.166,673$82.8M0.10%+102,721+160.6%Added
Lord, Abbett & Co. LLC166,581$82.7M0.24%+720.0%Added
Capital International Inc164,407$81.7M0.57%+2,684+1.7%Added
Quantinno Capital Management LP163,085$81.0M0.10%+36,481+28.8%Added
Carmignac Gestion163,045$81.0M1.05%+14,846+10.0%Added
Stifel Financial Corp162,151$80.5M0.07%+1,099+0.7%Added
Nomura Asset Management International Inc.159,549$79.3M0.12%+3,065+2.0%Added
Danske Bank A/S158,064$78.5M0.16%+5,058+3.3%Added
Mirae Asset Global ETFs Holdings Ltd.150,692$74.7M0.09%−21,233−12.4%Reduced
Rockefeller Capital Management L.P.149,476$74.2M0.11%−179−0.1%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund148,682$73.9M0.35%−1,280−0.9%Reduced
Harvest Portfolios Group Inc.148,195$73.6M1.04%+148,195New
Birch Hill Investment Advisors LLC147,702$73.4M2.97%−3,093−2.1%Reduced
Balyasny Asset Management LLC145,005$72.0M0.13%+104,868+261.3%Added
Susquehanna International Group, LLP144,174$71.6M0.06%+123,953+613.0%Added
Van Eck Associates Corp143,881$71.5M0.04%−2,235−1.5%Reduced
Allspring Global Investments Holdings, LLC140,631$70.0M0.11%+16,871+13.6%Added
Provident Investment Management, Inc.140,728$69.9M6.79%−6,892−4.7%Reduced
Woodline Partners LP140,288$69.7M0.22%+5,334+4.0%Added
Asset Management One Co.,Ltd.139,597$69.3M0.18%−2,352−1.7%Reduced
Man Group plc139,233$69.2M0.13%−97,565−41.2%Reduced
SEB Asset Management AB138,097$68.6M0.26%−2,854−2.0%Reduced
State of Wisconsin Investment Board135,798$67.5M0.14%−750−0.5%Reduced
Teacher Retirement System of Texas135,619$67.4M0.18%+11,302+9.1%Added
Connor, Clark & Lunn Investment Management Ltd.135,236$67.2M0.13%−116,475−46.3%Reduced
Mariner, LLC134,614$66.9M0.07%+3,014+2.3%Added
Prudential Financial Inc133,294$66.2M0.07%+1,734+1.3%Added
Los Angeles Capital Management LLC130,802$65.0M0.24%+65,865+101.4%Added
Vanguard Investments Australia, Ltd.130,109$64.6M0.16%+3,848+3.0%Added
SEI Investments Co129,981$64.6M0.06%−3,245−2.4%Reduced
Colony Group, LLC128,958$64.1M0.07%−2,477−1.9%Reduced
KBC Group NV128,466$63.8M0.14%+1,258+1.0%Added
Creative Planning127,672$63.4M0.04%+18,148+16.6%Added
ABN AMRO Bank N.V.125,970$62.5M0.81%+7,621+6.4%Added
Bowen Hanes & Co Inc135,399$60.5M1.47%00.0%Unchanged
Nomura Asset Management Co Ltd120,235$59.7M0.13%−932−0.8%Reduced
Credit Agricole S A115,955$57.6M0.15%−6,410−5.2%Reduced
Guggenheim Capital LLC115,233$57.2M0.37%+14,847+14.8%Added
Treasurer of the State of North Carolina108,303$53.8M0.14%−360−0.3%Reduced
DnB Asset Management AS108,106$53.7M0.15%+795+0.7%Added
Banco Santander, S.A.108,075$53.7M0.33%+8,687+8.7%Added
Storebrand Asset Management AS107,628$53.5M0.13%+5,061+4.9%Added
Truist Financial Corp106,967$53.1M0.06%−7,482−6.5%Reduced
KLP Kapitalforvaltning AS104,741$52.0M0.17%+9,360+9.8%Added
CIBC Asset Management Inc104,292$51.8M0.11%−2,601−2.4%Reduced
CI Private Wealth, LLC103,755$51.5M0.07%+17,263+20.0%Added
Intermede Investment Partners Ltd101,619$51.5M2.17%−4,751−4.5%Reduced
Mackenzie Financial Corp102,928$51.1M0.05%+6,219+6.4%Added
Country Trust Bank100,360$49.9M0.87%−4,715−4.5%Reduced
Public Employees Retirement System of Ohio98,068$48.7M0.14%−4,917−4.8%Reduced
Raiffeisen Bank International AG97,170$48.6M0.57%−4,265−4.2%Reduced
Capital International Ltd97,334$48.3M1.58%+1,460+1.5%Added
Toroso Investments, LLC95,685$47.5M0.12%+3,604+3.9%Added
Kovitz Investment Group Partners, LLC95,246$47.3M1.05%+4,361+4.8%Added
Virginia Retirement Systems Et Al94,060$46.7M0.28%00.0%Unchanged
PFA Pension, Forsikringsaktieselskab93,959$46.7M0.12%−41,037−30.4%Reduced
Lazard Asset Management LLC93,287$46.3M0.07%−119,844−56.2%Reduced
State of Tennessee, Treasury Department93,032$46.2M0.14%+11,364+13.9%Added
Swiss Life Asset Management Ltd91,614$45.5M0.19%+9,040+10.9%Added
Susquehanna Portfolio Strategies, LLC90,928$45.2M0.72%+61,739+211.5%Added
Janney Montgomery Scott LLC85,735$42.6M0.08%+1,411+1.7%Added
Toronto Dominion Bank85,391$42.4M0.07%+6,919+8.8%Added
Abn Amro Investment Solutions84,631$42.0M0.36%+16,415+24.1%Added
Resona Asset Management Co.,Ltd.84,092$41.8M0.20%−6,220−6.9%Reduced
Eurizon Capital SGR S.p.A.82,582$41.0M0.11%+1,073+1.3%Added
State of New Jersey Common Pension Fund D82,245$40.9M0.14%−4,465−5.1%Reduced
Fifth Third Bancorp81,898$40.7M0.07%−6,601−7.5%Reduced
Vontobel Holding Ltd.81,525$40.5M0.14%−1,855−2.2%Reduced
Lansforsakringar Fondforvaltning AB (publ)79,627$39.6M0.18%−4,219−5.0%Reduced
Cetera Investment Advisers78,107$38.8M0.04%+5,474+7.5%Added
Erste Asset Management GmbH76,558$38.2M0.30%−15,400−16.7%Reduced
Nissay Asset Management Corp75,743$37.6M0.16%+4,280+6.0%Added
Calamos Advisors LLC75,388$37.4M0.14%−2,498−3.2%Reduced
Mn Services Vermogensbeheer B.V.74,100$36.8M0.28%+74,100New
Pacer Advisors, Inc.72,465$36.0M0.09%−16,398−18.5%Reduced
Czech National Bank72,243$35.9M0.20%+3,067+4.4%Added