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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Daiwa Securities Group Inc.71,534$35.5M0.08%+3,995+5.9%Added
Capital Fund Management S.A.71,088$35.3M0.25%−51,846−42.2%Reduced
Arizona State Retirement System70,580$35.1M0.18%+1,065+1.5%Added
The PNC Financial Services Group, Inc.69,358$34.5M0.02%−2,584−3.6%Reduced
State of Michigan Retirement System67,823$33.7M0.15%−1,300−1.9%Reduced
Gateway Investment Advisers LLC67,289$33.4M0.33%+168+0.3%Added
STRS Ohio66,679$33.1M0.12%−7,484−10.1%Reduced
Rafferty Asset Management, LLC65,798$32.7M0.07%+11,226+20.6%Added
Apollon Wealth Management, LLC63,910$31.7M0.39%+25,315+65.6%Added
Sumitomo Mitsui DS Asset Management Company, Ltd63,330$31.5M0.22%−492−0.8%Reduced
GF Fund Management Co. Ltd.62,678$31.1M0.37%−1,913−3.0%Reduced
Rakuten Investment Management, Inc.61,183$30.6M0.09%+8,493+16.1%Added
Assetmark, Inc61,055$30.3M0.05%+1,101+1.8%Added
Trillium Asset Management, LLC60,105$29.9M0.92%−39,657−39.8%Reduced
Tredje AP-fonden59,459$29.5M0.13%−14,340−19.4%Reduced
Natixis59,095$29.4M0.14%+10,903+22.6%Added
Foster Dykema Cabot & Partners, LLC58,233$28.9M1.68%+441+0.8%Added
MetLife Investment Management58,072$28.8M0.13%−12,732−18.0%Reduced
IFM Investors Pty Ltd57,713$28.7M0.19%+6,643+13.0%Added
Hardman Johnston Global Advisors LLC57,683$28.7M1.01%−674−1.2%Reduced
Moody Lynn & Lieberson, LLC56,624$28.1M1.48%−1,016−1.8%Reduced
Nisa Investment Advisors, LLC56,455$28.0M0.09%−1,728−3.0%Reduced
Atwood & Palmer Inc56,357$28.0M1.49%+604+1.1%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys56,059$27.8M0.14%−3,108−5.3%Reduced
Hemenway Trust Co LLC55,995$27.8M1.94%+4,496+8.7%Added
Zacks Investment Management55,052$27.3M0.19%−30−0.1%Reduced
Edgemoor Investment Advisors, Inc.55,020$27.3M1.86%−395−0.7%Reduced
Reynders McVeigh Capital Management, LLC54,499$27.1M1.20%−165−0.3%Reduced
PensionDanmark Pensionsforsikringsaktieselskab54,094$26.9M0.22%+4,890+9.9%Added
Beacon Investment Advisory Services, Inc.53,380$26.5M0.99%−2,724−4.9%Reduced
Retirement Systems of Alabama53,319$26.5M0.08%−619−1.1%Reduced
Cullinan Associates Inc51,762$25.7M1.94%00.0%Unchanged
Hallmark Capital Management Inc51,329$25.5M1.47%+1,190+2.4%Added
Citizens Financial Group Inc50,988$25.3M0.31%+1,164+2.3%Added
Pinebridge Investments LLC50,819$25.2M0.21%−4,281−7.8%Reduced
Commonwealth Equity Services, LLC50,813$25.2M0.03%−4,159−7.6%Reduced
Empowered Funds, LLC50,197$24.9M0.13%+8,460+20.3%Added
Advisor Group Holdings, Inc.49,586$24.6M0.03%+5,614+12.8%Added
HighTower Advisors, LLC49,020$24.3M0.02%−16,664−25.4%Reduced
USS Investment Management Ltd48,893$24.3M0.10%+1,765+3.7%Added
Davidson Investment Advisors48,710$24.2M0.99%−2,512−4.9%Reduced
China Universal Asset Management Co., Ltd.48,265$24.0M1.43%+4,363+9.9%Added
Amalgamated Bank47,716$23.7M0.16%−5,553−10.4%Reduced
Adams Diversified Equity Fund, Inc.47,300$23.5M0.72%+47,300New
Quadrature Capital Ltd46,945$23.3M0.20%+46,945New
C WorldWide Group Holding A/S46,057$22.9M0.55%00.0%Unchanged
Pathstone Holdings, LLC45,952$22.9M0.07%+1,690+3.8%Added
Xponance, Inc.45,980$22.8M0.14%−24,734−35.0%Reduced
Ossiam45,879$22.8M0.30%+6,522+16.6%Added
Lido Advisors, LLC45,347$22.5M0.08%+1,836+4.2%Added
W.G. Shaheen & Associates DBA Whitney & Co44,714$22.2M1.62%+597+1.4%Added
Zurich Insurance Group Ltd43,589$21.7M0.15%−1,029−2.3%Reduced
Wealth Enhancement Advisory Services, LLC45,889$21.5M0.04%+5,221+12.8%Added
New York Life Investment Management LLC43,218$21.5M0.15%+5,149+13.5%Added
JustInvest LLC43,151$21.4M0.18%+1,528+3.7%Added
Martingale Asset Management L P42,729$21.2M0.50%−2,021−4.5%Reduced
Federated Hermes, Inc.42,663$21.2M0.03%−29,159−40.6%Reduced
Acadian Asset Management LLC42,122$20.9M0.02%+16,254+62.8%Added
O'Shaughnessy Asset Management, LLC42,063$20.9M0.10%−19,804−32.0%Reduced
Wealthfront Advisers LLC41,608$20.7M0.04%−4,787−10.3%Reduced
Public Sector Pension Investment Board41,334$20.5M0.05%+157+0.4%Added
Varma Mutual Pension Insurance Co40,826$20.3M0.11%−2,800−6.4%Reduced
HRT Financial LP40,533$20.1M0.04%+13,743+51.3%Added
Tweedy, Browne Co LLC40,121$19.9M1.51%−266−0.7%Reduced
Flputnam Investment Management Co40,116$19.9M0.24%+618+1.6%Added
Integral Health Asset Management, LLC40,000$19.9M0.82%00.0%Unchanged
Sanctuary Advisors, LLC39,811$19.8M0.09%−9,549−19.3%Reduced
Banco Bilbao Vizcaya Argentaria, S.A.39,809$19.7M0.12%−969−2.4%Reduced
Americana Partners, LLC38,914$19.3M0.44%+9,141+30.7%Added
MML Investors Services, LLC38,907$19.3M0.04%+5,488+16.4%Added
Fideuram - Intesa Sanpaolo Private Banking S.P.A.38,752$19.2M0.58%+3,761+10.7%Added
Utah Retirement Systems38,602$19.2M0.18%−2,663−6.5%Reduced
Nippon Life Global Investors Americas, Inc.38,230$19.0M0.76%+35,730+1,429.2%Added
British Columbia Investment Management Corp38,144$18.9M0.12%+3,173+9.1%Added
Police & Firemen's Retirement System of New Jersey37,982$18.9M0.14%−1,079−2.8%Reduced
Macquarie Group Ltd37,980$18.9M0.08%−2,256−5.6%Reduced
Aristotle Atlantic Partners, LLC37,489$18.6M0.77%−43−0.1%Reduced
Ieq Capital, LLC37,339$18.5M0.09%+10,164+37.4%Added
Bailard, Inc.37,314$18.5M0.38%−548−1.4%Reduced
Segall Bryant & Hamill, LLC37,072$18.4M0.22%−1,001−2.6%Reduced
Teachers Retirement System of the State of Kentucky36,725$18.2M0.12%00.0%Unchanged
Captrust Financial Advisors35,471$17.6M0.03%+3,379+10.5%Added
BI Asset Management Fondsmaeglerselskab A/S35,137$17.5M0.14%−14,394−29.1%Reduced
Illinois Municipal Retirement Fund34,259$17.0M0.19%−6,314−15.6%Reduced
Ilmarinen Mutual Pension Insurance Co33,800$16.8M0.11%00.0%Unchanged
CAPROCK Group, Inc.33,721$16.8M0.32%+3,714+12.4%Added
Elo Mutual Pension Insurance Co33,374$16.6M0.21%+1,996+6.4%Added
McRae Capital Management Inc33,191$16.5M3.24%−932−2.7%Reduced
William Blair Investment Management, LLC32,172$16.0M0.05%−7,375−18.6%Reduced
US Bancorp32,020$15.9M0.02%+2,239+7.5%Added
State of Alaska, Department of Revenue31,836$15.8M0.16%−1,344−4.1%Reduced
AIA Group Ltd31,601$15.7M0.20%+2,079+7.0%Added
Oregon Public Employees Retirement Fund31,235$15.5M0.17%+2,152+7.4%Added
Barlow Wealth Partners, Inc.30,786$15.3M1.66%+375+1.2%Added
Vinva Investment Management Ltd30,687$15.3M0.10%+21,156+222.0%Added
Mercer Global Advisors Inc30,705$15.3M0.02%+7,943+34.9%Added
Rhenman & Partners Asset Management AB30,685$15.2M1.44%−12,800−29.4%Reduced
Nordea Investment Management AB30,496$15.1M0.01%+3,325+12.2%Added
Foster Victor Wealth Advisors, LLC31,606$15.1M0.79%+852+2.8%Added
Longaeva Partners L.P.30,279$15.0M0.43%+5,344+21.4%Added