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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Los Angeles Capital Management LLC302,005$66.3M0.25%+147,876+95.9%Added
Virginia Retirement Systems Et Al300,900$66.1M0.61%−5,800−1.9%Reduced
Nomura Asset Management Co Ltd296,854$65.2M0.33%+56,197+23.4%Added
Ensign Peak Advisors, Inc295,678$64.9M0.12%−151,534−33.9%Reduced
Skandinaviska Enskilda Banken AB (publ)287,924$64.0M0.33%−10,161−3.4%Reduced
Mirae Asset Global Investments Co., Ltd.285,187$62.7M0.13%+37,357+15.1%Added
Avidity Partners Management LP280,000$61.5M1.30%−646,400−69.8%Reduced
Panagora Asset Management Inc274,260$60.2M0.32%−115,628−29.7%Reduced
Tekla Capital Management LLC273,046$60.0M1.93%00.0%Unchanged
Nordea Investment Management AB266,994$59.4M0.07%+29,813+12.6%Added
Envestnet Asset Management Inc269,240$59.1M0.03%+20,854+8.4%Added
Federated Hermes, Inc.267,084$58.7M0.11%+16,440+6.6%Added
Scout Investments, Inc.258,758$56.8M0.83%+12,385+5.0%Added
Mitsubishi UFJ Trust & Banking Corp254,769$55.9M0.12%−17,977−6.6%Reduced
Natixis Investment Managers International254,730$55.9M3.10%+254,730New
Citadel Advisors LLC252,591$55.5M0.06%−161,538−39.0%Reduced
Birch Hill Investment Advisors LLC247,239$54.3M2.69%+50,095+25.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.246,379$54.1M0.18%+42,137+20.6%Added
State of Tennessee, Treasury Department243,142$53.4M0.20%+49,402+25.5%Added
Neuberger Berman Group LLC242,811$52.4M0.04%−43,385−15.2%Reduced
Korea Investment CORP223,697$49.1M0.13%+78,111+53.7%Added
Adage Capital Partners GP, L.L.C.220,890$48.5M0.09%+46,930+27.0%Added
Guggenheim Capital LLC211,672$46.5M0.24%+4,577+2.2%Added
Balyasny Asset Management LLC211,347$46.4M0.20%+56,709+36.7%Added
Hardman Johnston Global Advisors LLC208,624$45.8M1.24%+19,950+10.6%Added
State of Wisconsin Investment Board206,800$45.4M0.09%−62,201−23.1%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main203,786$45.0M0.06%−28,486−12.3%Reduced
Mn Services Vermogensbeheer B.V.198,400$43.6M0.26%+4,800+2.5%Added
Robeco Institutional Asset Management B.V.198,318$43.6M0.09%−4,637−2.3%Reduced
Bowen Hanes & Co Inc194,120$42.6M1.20%+15,475+8.7%Added
Handelsbanken Fonder AB194,044$42.6M0.21%+121,656+168.1%Added
Welch & Forbes LLC189,930$41.7M0.62%−12,107−6.0%Reduced
Provident Investment Management, Inc.185,179$40.7M3.67%+1,813+1.0%Added
Putnam Investments LLC181,572$39.9M0.06%−337,467−65.0%Reduced
Teachers Retirement System of the State of Kentucky180,267$39.6M0.35%−1,345−0.7%Reduced
Country Trust Bank179,668$39.5M1.07%+19,269+12.0%Added
Asset Management One Co.,Ltd.170,322$38.0M0.13%+13,382+8.5%Added
Victory Capital Management Inc170,494$37.4M0.03%+4,717+2.8%Added
BNP Paribas Arbitrage, SA170,125$37.4M0.09%+43,429+34.3%Added
Rhenman & Partners Asset Management AB165,000$36.7M2.44%00.0%Unchanged
Van Eck Associates Corp159,522$35.0M0.08%−19,656−11.0%Reduced
Public Employees Retirement System of Ohio157,009$34.5M0.12%−7,845−4.8%Reduced
Toronto Dominion Bank155,281$34.1M0.05%−69,234−30.8%Reduced
Varenne Capital Partners155,070$34.1M5.05%+155,070New
Chevy Chase Trust Holdings, Inc.152,750$33.5M0.11%−6,536−4.1%Reduced
State of New Jersey Common Pension Fund D152,629$33.5M0.10%−2,027−1.3%Reduced
Marshall Wace, LLP150,000$32.9M0.07%−406,678−73.1%Reduced
Melqart Asset Management (UK) Ltd150,000$32.9M1.86%+10,000+7.1%Added
Twin Tree Management, LP140,819$30.9M0.75%+122,616+673.6%Added
Voloridge Investment Management, LLC139,353$30.6M0.17%−397,543−74.0%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.136,168$30.3M0.12%+19,729+16.9%Added
Zurcher Kantonalbank (Zurich Cantonalbank)126,303$27.7M0.13%−19,306−13.3%Reduced
AMF Pensionsforsakring AB125,917$27.7M0.19%−16,532−11.6%Reduced
Renaissance Group LLC125,115$27.5M1.12%+6,265+5.3%Added
South Dakota Investment Council124,294$27.3M0.46%+45,680+58.1%Added
LPL Financial LLC120,502$26.5M0.02%+7,919+7.0%Added
Vontobel Holding Ltd.116,697$26.0M0.22%+18,953+19.4%Added
Voya Investment Management LLC115,847$25.4M0.05%−13,143−10.2%Reduced
Treasurer of the State of North Carolina114,884$25.2M0.13%+1,673+1.5%Added
Nikko Asset Management Americas, Inc.113,989$24.9M0.13%−13,207−10.4%Reduced
Teacher Retirement System of Texas112,760$24.8M0.11%−16,482−12.8%Reduced
STRS Ohio109,431$24.0M0.08%−2,688−2.4%Reduced
C WorldWide Group Holding A/S108,557$23.8M0.23%00.0%Unchanged
Capital International Inc107,173$23.5M0.22%+13,572+14.5%Added
Clough Capital Partners L P107,110$23.5M1.58%+17,500+19.5%Added
American International Group, Inc.106,388$23.4M0.12%−2,130−2.0%Reduced
Woodline Partners LP103,780$22.8M0.33%+23,293+28.9%Added
Dai-Ichi Life Insurance Company, Ltd102,404$22.5M0.29%−18,000−14.9%Reduced
Bank of Nova Scotia101,259$22.2M0.03%−387,200−79.3%Reduced
Cullinan Associates Inc98,910$21.7M1.11%−215−0.2%Reduced
Group One Trading, L.P.98,437$21.6M0.41%+26,514+36.9%Added
Roosevelt Investment Group LLC97,140$21.3M1.18%+1,673+1.8%Added
Stifel Financial Corp96,333$21.2M0.03%−16,531−14.6%Reduced
Nisa Investment Advisors, LLC86,062$20.9M0.16%−5,652−6.2%Reduced
Hallmark Capital Management Inc95,238$20.9M1.68%−1,125−1.2%Reduced
Summit Global Investments95,044$20.9M1.34%+95,044New
Standard Life Aberdeen plc94,623$20.8M0.05%−420,216−81.6%Reduced
Aviva PLC93,524$20.5M0.09%−8,617−8.4%Reduced
Banque Pictet & Cie SA92,501$20.3M0.15%+57,611+165.1%Added
M.D. Sass Investors Services, Inc.91,885$20.2M3.14%+91,885New
Calamos Advisors LLC91,150$20.0M0.08%−19,807−17.9%Reduced
Ossiam90,054$19.8M0.52%+87,369+3,254.0%Added
Gateway Investment Advisers LLC89,946$19.8M0.19%−12,423−12.1%Reduced
Storebrand Asset Management AS89,224$19.6M0.09%−4,632−4.9%Reduced
Mackenzie Financial Corp87,449$19.2M0.03%+1,896+2.2%Added
Royal London Asset Management Ltd86,787$19.1M0.07%−4,005−4.4%Reduced
Healthcare of Ontario Pension Plan Trust Fund85,144$18.7M0.04%−44,016−34.1%Reduced
Great Point Partners LLC85,000$18.7M4.17%00.0%Unchanged
Truist Financial Corp84,138$18.5M0.03%+2,887+3.6%Added
Capital International Ltd83,591$18.4M0.93%+10,036+13.6%Added
Eagle Health Investments LP82,144$18.0M4.39%+52,600+178.0%Added
Magnetar Financial LLC81,724$17.9M0.18%+17,487+27.2%Added
NN Investment Partners Holdings N.V.81,132$17.8M0.09%−25,080−23.6%Reduced
2Xideas AG80,226$17.6M1.06%+23,363+41.1%Added
EULAV Asset Management80,000$17.6M0.44%−28,000−25.9%Reduced
Alberta Investment Management Corp79,200$17.4M0.11%−12,452−13.6%Reduced
BI Asset Management Fondsmaeglerselskab A/S78,877$17.3M0.64%−443−0.6%Reduced
Forsta Ap-Fonden77,300$17.0M0.17%+1,100+1.4%Added
Kingdon Capital Management, L.L.C.77,300$17.0M2.54%+77,300New
International Biotechnology Trust PLC77,222$17.0M3.78%00.0%Unchanged