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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Baird Financial Group, Inc.76,028$16.7M0.04%+1,838+2.5%Added
Andra AP-fonden75,600$16.6M0.34%+4,100+5.7%Added
Banco Bilbao Vizcaya Argentaria, S.A.74,639$16.6M0.22%+49,830+200.9%Added
Amalgamated Bank71,174$15.6M0.12%+5,885+9.0%Added
Arizona State Retirement System71,052$15.6M0.12%−1,136−1.6%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund70,487$15.5M0.14%−700−1.0%Reduced
Van Hulzen Asset Management, LLC69,901$15.4M1.68%+69,901New
PFS Investments Inc.68,783$15.1M0.29%+744+1.1%Added
CIBC Asset Management Inc67,642$14.9M0.05%+6,305+10.3%Added
Jane Street Group, LLC66,068$14.5M0.03%−69,179−51.2%Reduced
Commonwealth Equity Services, LLC65,403$14.4M0.03%−9,388−12.6%Reduced
HighTower Advisors, LLC64,863$14.2M0.03%+11,205+20.9%Added
USS Investment Management Ltd64,412$14.1M0.11%00.0%Unchanged
Davidson Investment Advisors64,309$14.1M1.01%−413−0.6%Reduced
State of Michigan Retirement System64,034$14.1M0.07%−1,100−1.7%Reduced
HRT Financial LP63,603$14.0M0.08%+63,603New
Erste Asset Management GmbH61,200$13.7M0.25%−800−1.3%Reduced
Bridger Management, LLC59,400$13.0M1.69%+59,400New
Profund Advisors LLC58,608$12.9M0.42%−8,612−12.8%Reduced
Illinois Municipal Retirement Fund58,502$12.8M0.36%+11,467+24.4%Added
Capital Group Private Client Services, Inc.57,166$12.6M0.13%−4,971−8.0%Reduced
MetLife Investment Management56,175$12.3M0.10%−2,419−4.1%Reduced
Greenwood Capital Associates LLC55,316$12.1M1.72%−232−0.4%Reduced
Janney Montgomery Scott LLC54,887$12.1M0.05%+2,439+4.7%Added
Rafferty Asset Management, LLC54,435$12.0M0.06%+7,270+15.4%Added
Thrivent Financial for Lutherans52,406$11.5M0.02%+8,056+18.2%Added
The PNC Financial Services Group, Inc.51,537$11.3M0.01%+20,397+65.5%Added
W.G. Shaheen & Associates DBA Whitney & Co50,135$11.0M1.62%+733+1.5%Added
Squarepoint Ops LLC49,545$10.9M0.05%−104,211−67.8%Reduced
Advisor Group Holdings, Inc.48,529$10.7M0.02%+15,222+45.7%Added
Industrial Alliance Investment Management Inc.47,632$10.5M0.24%+47,632New
Point72 Asset Management, L.P.47,600$10.5M0.05%+47,600New
Citizens Financial Group Inc47,500$10.4M0.35%+42,987+952.5%Added
Banco Santander, S.A.47,262$10.4M0.06%+1,300+2.8%Added
Capital International Sarl46,555$10.2M0.49%+33,939+269.0%Added
Utah Retirement Systems46,239$10.2M0.13%−600−1.3%Reduced
Schroder Investment Management Group45,894$10.1M0.01%−1,285−2.7%Reduced
British Columbia Investment Management Corp45,612$10.0M0.06%−2,337−4.9%Reduced
ExodusPoint Capital Management, LP44,933$9.87M0.12%+5,821+14.9%Added
Weiss Multi-Strategy Advisers LLC44,693$9.81M0.23%−10,456−19.0%Reduced
Edgemoor Investment Advisors, Inc.44,328$9.73M1.00%+9,654+27.8%Added
ING Groep NV43,987$9.66M0.09%+17,641+67.0%Added
Factory Mutual Insurance Co43,200$9.66M0.14%−139,455−76.3%Reduced
Gulf International Bank (UK) Ltd43,475$9.55M0.13%−8,919−17.0%Reduced
Shelter Mutual Insurance Co43,300$9.51M2.47%00.0%Unchanged
Brookfield Asset Management Inc.42,697$9.38M0.04%+29,816+231.5%Added
Public Sector Pension Investment Board42,425$9.32M0.05%−1,290−3.0%Reduced
Employees Retirement System of Texas42,200$9.27M0.10%00.0%Unchanged
Thompson Siegel & Walmsley LLC42,062$9.24M0.13%−3,039−6.7%Reduced
Bulltick Wealth Management, LLC40,172$8.82M1.80%−2,146−5.1%Reduced
Sector Gamma AS39,069$8.58M2.02%+39,069New
Seizert Capital Partners, LLC38,598$8.48M0.38%+3,640+10.4%Added
Nicholas Investment Partners, LP38,287$8.41M0.53%+38,287New
Mackay Shields LLC37,983$8.34M0.07%−1,594−4.0%Reduced
Exencial Wealth Advisors, LLC37,817$8.30M0.40%+1,213+3.3%Added
State of Alaska, Department of Revenue36,800$8.08M0.08%−3,035−7.6%Reduced
Prudential PLC36,041$7.92M0.11%−1,126−3.0%Reduced
Comerica Bank34,325$7.79M0.06%−52,411−60.4%Reduced
Jacobs Levy Equity Management, Inc35,264$7.74M0.05%−421,858−92.3%Reduced
Texas Permanent School Fund35,018$7.69M0.09%−5,060−12.6%Reduced
IFM Investors Pty Ltd34,197$7.51M0.14%−403−1.2%Reduced
SG Americas Securities, LLC34,154$7.50M0.05%+25,894+313.5%Added
SEI Investments Co34,329$7.48M0.01%−1,291−3.6%Reduced
AlphaCrest Capital Management LLC33,735$7.41M0.28%+2,115+6.7%Added
Azimuth Capital Management LLC33,575$7.37M0.30%−194−0.6%Reduced
Mutual of America Capital Management LLC33,550$7.37M0.07%−464−1.4%Reduced
Metropolitan Life Insurance Co33,498$7.36M0.10%−1,335−3.8%Reduced
Yousif Capital Management, LLC33,148$7.28M0.08%+33,148New
Hudson Bay Capital Management LP32,500$7.14M0.08%−30,000−48.0%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys31,913$7.01M0.07%−598−1.8%Reduced
Cubist Systematic Strategies, LLC31,888$7.00M0.07%−5,921−15.7%Reduced
LVM Capital Management Ltd31,846$6.99M0.93%+321+1.0%Added
Privium Fund Management B.V.31,000$6.90M1.37%+31,000New
Gabelli Funds LLC31,296$6.87M0.04%+6,000+23.7%Added
Walleye Capital LLC31,203$6.85M0.23%+2,373+8.2%Added
Boston Common Asset Management, LLC31,040$6.82M0.28%−505−1.6%Reduced
Private Advisor Group, LLC30,979$6.80M0.05%−903−2.8%Reduced
Beacon Investment Advisory Services, Inc.30,557$6.71M0.26%−5,945−16.3%Reduced
First Republic Investment Management, Inc.30,432$6.68M0.01%+23,254+324.0%Added
Vident Investment Advisory, LLC30,124$6.62M0.17%+9,645+47.1%Added
Rockefeller Capital Management L.P.30,121$6.61M0.03%+6,248+26.2%Added
Tower Research Capital LLC (TRC)29,743$6.53M0.11%+3,872+15.0%Added
TD Waterhouse Canada Inc.29,292$6.53M0.06%+29,292New
Louisiana State Employees Retirement System29,400$6.46M0.14%−100−0.3%Reduced
Varma Mutual Pension Insurance Co29,287$6.43M0.09%00.0%Unchanged
Shell Asset Management Co28,839$6.33M0.13%−8,012−21.7%Reduced
Tredje AP-fonden28,666$6.29M0.12%00.0%Unchanged
Nissay Asset Management Corp28,587$6.28M0.05%+1,026+3.7%Added
Ilmarinen Mutual Pension Insurance Co28,000$6.15M0.07%00.0%Unchanged
Philadelphia Trust Co26,985$5.93M0.43%+25,100+1,331.6%Added
Xponance, Inc.26,767$5.88M0.09%+3,078+13.0%Added
Atria Investments LLC26,620$5.85M0.10%+1,433+5.7%Added
Westpac Banking Corp26,000$5.71M0.06%−73−0.3%Reduced
Hartford Investment Management Co25,796$5.67M0.13%+1,605+6.6%Added
Distillate Capital Partners LLC25,728$5.65M0.95%+8,782+51.8%Added
Raymond James Financial Services Advisors, Inc.25,355$5.57M0.01%+742+3.0%Added
Fisher Asset Management, LLC25,271$5.55M0.00%+1,157+4.8%Added
Bender Robert & Associates30,110$5.46M1.58%00.0%Unchanged
Pura Vida Investments, LLC24,636$5.41M0.56%−5,364−17.9%Reduced
Covea Finance24,544$5.39M0.47%+24,544New