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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
PDT Partners, LLC24,508$5.38M0.41%−2,093−7.9%Reduced
Wealth Enhancement Advisory Services, LLC22,043$5.37M0.08%+22,043New
Shelton Capital Management24,277$5.33M0.19%+477+2.0%Added
Arrowstreet Capital, Limited Partnership24,249$5.33M0.01%+24,249New
Edgewood Management LLC24,088$5.29M0.01%00.0%Unchanged
AIMZ Investment Advisors, LLC24,080$5.29M2.06%+400+1.7%Added
Norinchukin Bank, The23,875$5.24M0.07%−1,919−7.4%Reduced
B. Metzler seel. Sohn & Co. AG23,315$5.19M0.07%+23,315New
Foster Victor Wealth Advisors, LLC22,933$5.19M0.71%+2,121+10.2%Added
Blair William & Co23,489$5.16M0.02%+7,239+44.5%Added
Scotia Capital Inc.23,483$5.16M0.03%+7,458+46.5%Added
Northwest Bancshares, Inc.23,445$5.15M1.01%+1,079+4.8%Added
Fagan Associates, Inc.23,419$5.14M0.98%+3,012+14.8%Added
Formuepleje A/S23,389$5.14M0.20%−3,953−14.5%Reduced
Meiji Yasuda Asset Management Co Ltd.23,206$5.10M0.32%+271+1.2%Added
Daiwa Securities Group Inc.23,175$5.09M0.03%+1,483+6.8%Added
Gotham Asset Management, LLC22,755$5.00M0.16%+2,488+12.3%Added
Beacon Pointe Advisors, LLC22,518$4.95M0.13%−6,314−21.9%Reduced
Connor, Clark & Lunn Investment Management Ltd.22,233$4.88M0.02%−2,476−10.0%Reduced
Cornerstone Advisors, LLC22,000$4.83M0.26%00.0%Unchanged
Sumitomo Mitsui DS Asset Management Company, Ltd21,815$4.79M0.10%+1,047+5.0%Added
Northwest & Ethical Investments L.P.21,641$4.75M0.14%+21,641New
Quantitative Investment Management, LLC21,622$4.75M0.67%+21,622New
Securian Asset Management, Inc21,523$4.73M0.09%−891−4.0%Reduced
Pacer Advisors, Inc.21,453$4.71M0.05%−7,435−25.7%Reduced
Advisors Asset Management, Inc.21,242$4.66M0.07%−4,458−17.3%Reduced
Sepio Capital, LP21,162$4.65M0.35%+333+1.6%Added
Oregon Public Employees Retirement Fund21,040$4.62M0.05%−609−2.8%Reduced
Pinebridge Investments, L.P.21,023$4.62M0.05%−94,562−81.8%Reduced
Davenport & Co LLC20,717$4.55M0.03%+2,318+12.6%Added
Associated Banc-Corp20,597$4.52M0.17%−5,480−21.0%Reduced
Natixis20,423$4.49M0.02%−166,652−89.1%Reduced
Edmond de Rothschild Holding S.A.20,039$4.40M0.10%−5,677−22.1%Reduced
Vestmark Advisory Solutions, Inc.19,982$4.39M0.25%−357−1.8%Reduced
Camden National Bank19,807$4.35M0.76%+281+1.4%Added
Keybank National Association19,769$4.34M0.02%−7,086−26.4%Reduced
Elo Mutual Pension Insurance Co19,658$4.32M0.12%+1,392+7.6%Added
Maryland State Retirement & Pension System19,543$4.29M0.11%00.0%Unchanged
Allstate Corp19,082$4.19M0.08%+12,315+182.0%Added
Wolverine Trading, LLC18,569$4.13M0.06%−4,402−19.2%Reduced
Kestra Advisory Services, LLC18,677$4.10M0.04%−1,802−8.8%Reduced
Pictet & Cie (Europe) SA18,242$4.01M0.14%−555−3.0%Reduced
Jump Financial, LLC18,167$3.99M0.25%+18,167New
IndexIQ Advisors LLC17,937$3.94M0.13%+195+1.1%Added
Knuff & Co LLC17,646$3.88M1.20%+634+3.7%Added
PointState Capital LP17,500$3.84M0.12%+17,500New
Ameritas Investment Partners, Inc.17,457$3.83M0.13%−252−1.4%Reduced
U.S. Capital Wealth Advisors, LLC17,110$3.76M0.15%−494−2.8%Reduced
Telos Capital Management, Inc.17,099$3.75M0.47%+581+3.5%Added
Knott David M Jr17,000$3.73M1.41%+17,000New
Captrust Financial Advisors16,686$3.66M0.03%−2,612−13.5%Reduced
Princeton Capital Management LLC16,581$3.64M1.04%−510−3.0%Reduced
Boston Private Wealth LLC16,372$3.60M0.06%+98+0.6%Added
Fifth Third Bancorp15,923$3.50M0.01%−1,130−6.6%Reduced
New Mexico Educational Retirement Board15,800$3.47M0.12%−1,100−6.5%Reduced
Winton Group Ltd15,797$3.47M0.21%+12,962+457.2%Added
Princeton Global Asset Management LLC15,782$3.47M0.97%−1,058−6.3%Reduced
Essex Investment Management Co LLC15,570$3.42M0.39%−1,060−6.4%Reduced
Harvest Volatility Management LLC15,516$3.41M0.17%+3,573+29.9%Added
Livforsakringsbolaget Skandia, Omsesidigt15,387$3.38M0.21%−1,500−8.9%Reduced
Kentucky Retirement Systems15,368$3.38M0.14%+111+0.7%Added
Enterprise Trust & Investment Co15,340$3.37M1.18%+7,415+93.6%Added
Swiss Life Asset Management Ltd15,111$3.32M0.04%−35,848−70.3%Reduced
Nomura Holdings Inc15,101$3.32M0.02%−320−2.1%Reduced
Ausdal Financial Partners, Inc.14,981$3.29M0.44%+14,981New
Madison Asset Management, LLC14,728$3.23M0.04%−403−2.7%Reduced
Oppenheimer Asset Management Inc.14,711$3.23M0.04%+3,268+28.6%Added
FDx Advisors, Inc.14,566$3.20M0.09%+4,443+43.9%Added
Tealwood Asset Management Inc14,297$3.14M1.26%−595−4.0%Reduced
US Bancorp14,189$3.12M0.00%+1,895+15.4%Added
Barrett Asset Management, LLC14,183$3.12M0.12%−14,427−50.4%Reduced
Silvercrest Asset Management Group LLC14,070$3.09M0.02%00.0%Unchanged
Kinneret Advisory, LLC14,025$3.08M0.32%00.0%Unchanged
Glenmede Trust Co NA13,947$3.06M0.01%−1,345−8.8%Reduced
Te Ahumairangi Investment Management Ltd13,770$3.02M0.39%+13,770New
Leonteq Securities AG13,720$3.01M0.14%−27,760−66.9%Reduced
Cetera Investment Advisers13,570$2.98M0.04%−312−2.2%Reduced
Simplex Trading, LLC13,565$2.98M0.10%+4,265+45.9%Added
Cookson Peirce & Co Inc13,537$2.97M0.17%+13,537New
Brinker Capital Investments, LLC13,424$2.95M0.04%+2,301+20.7%Added
Boothbay Fund Management, LLC13,421$2.95M0.10%+635+5.0%Added
Seeyond13,123$2.88M0.27%+3,655+38.6%Added
First Citizens Bank & Trust Co12,967$2.85M0.11%+164+1.3%Added
MML Investors Services, LLC12,862$2.82M0.02%+1,729+15.5%Added
E. Ohman J:or Asset Management AB12,800$2.81M0.08%+900+7.6%Added
Northwestern Mutual Investment Management Company, LLC12,616$2.77M0.05%−382−2.9%Reduced
Berry Street Capital Management LLP12,500$2.75M0.53%+12,500New
Cutter & CO Brokerage, Inc.12,430$2.73M0.75%+310+2.6%Added
Bridgewater Associates, LP12,417$2.73M0.02%−2,700−17.9%Reduced
Two Sigma Advisers, LP12,300$2.70M0.01%−770,400−98.4%Reduced
Cambridge Investment Research Advisors, Inc.12,189$2.68M0.01%−45−0.4%Reduced
Exchange Traded Concepts, LLC12,110$2.66M0.05%−3,346−21.6%Reduced
Capstone Investment Advisors, LLC12,060$2.65M0.04%−89,256−88.1%Reduced
PEAK6 Investments LLC11,815$2.60M0.07%−23,374−66.4%Reduced
National Asset Management, Inc.11,814$2.60M0.07%−5,007−29.8%Reduced
Heirloom Wealth Management11,200$2.57M2.21%+11,200New
Bokf, NA11,588$2.54M0.04%−1,445−11.1%Reduced
Stephens Inc11,503$2.53M0.04%−2,496−17.8%Reduced
Pensionfund Sabic11,500$2.52M0.47%+11,500New
Central Trust Co11,460$2.52M0.07%−3,000−20.7%Reduced