Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sivik Global Healthcare LLC | 14,000 | $5.48M | 2.88% | +14,000 | New |
| Sequoia Financial Advisors, LLC | 13,980 | $5.48M | 0.03% | −393−2.7% | Reduced |
| Ethic Inc. | 13,971 | $5.47M | 0.09% | +2,476+21.5% | Added |
| New Age Alpha Advisors, LLC | 13,939 | $5.46M | 0.23% | −1,761−11.2% | Reduced |
| Omers Administration Corp | 13,754 | $5.39M | 0.04% | 00.0% | Unchanged |
| Empowered Funds, LLC | 13,583 | $5.32M | 0.05% | +3,761+38.3% | Added |
| Metis Global Partners, LLC | 13,424 | $5.26M | 0.12% | −694−4.9% | Reduced |
| Princeton Global Asset Management LLC | 13,359 | $5.23M | 0.87% | −1,666−11.1% | Reduced |
| Diversify Wealth Management, LLC | 12,214 | $5.20M | 0.30% | −774−6.0% | Reduced |
| Beacon Pointe Advisors, LLC | 13,284 | $5.20M | 0.04% | −2,745−17.1% | Reduced |
| Vident Advisory, LLC | 13,222 | $5.18M | 0.05% | −5,278−28.5% | Reduced |
| Ossiam | 12,940 | $5.07M | 0.07% | +8,340+181.3% | Added |
| Fisher Funds Management LTD | 12,898 | $5.05M | 0.13% | 00.0% | Unchanged |
| Gulf International Bank (UK) Ltd | 12,879 | $5.04M | 0.17% | −255−1.9% | Reduced |
| Maryland State Retirement & Pension System | 12,846 | $5.03M | 0.11% | +346+2.8% | Added |
| Leuthold Group, LLC | 12,843 | $5.03M | 0.55% | +12,843 | New |
| Chicago Capital, LLC | 12,824 | $5.02M | 0.12% | −51−0.4% | Reduced |
| Greenwood Capital Associates LLC | 12,812 | $5.02M | 0.58% | +2,514+24.4% | Added |
| Thematics Asset Management | 12,629 | $4.95M | 0.22% | +2,031+19.2% | Added |
| Compagnie Lombard Odier SCmA | 12,565 | $4.92M | 0.05% | 00.0% | Unchanged |
| Hamilton Capital Partners Inc. | 12,329 | $4.83M | 0.20% | +2,813+29.6% | Added |
| M&T Bank Corp | 12,324 | $4.83M | 0.02% | −5,359−30.3% | Reduced |
| Securian Asset Management, Inc | 12,316 | $4.82M | 0.13% | −1,126−8.4% | Reduced |
| Morningstar Investment Management LLC | 12,305 | $4.82M | 0.18% | +11,075+900.4% | Added |
| Kidder Stephen W | 12,298 | $4.82M | 1.38% | +168+1.4% | Added |
| Dai-Ichi Life Insurance Company, Ltd | 12,138 | $4.75M | 0.12% | −12,898−51.5% | Reduced |
| Northwest Bancshares, Inc. | 12,138 | $4.75M | 0.79% | +935+8.3% | Added |
| Covenant Asset Management, LLC | 12,104 | $4.74M | 0.90% | −51−0.4% | Reduced |
| Captrust Financial Advisors | 12,074 | $4.73M | 0.01% | −1,238−9.3% | Reduced |
| ING Groep NV | 11,989 | $4.70M | 0.03% | +11,989 | New |
| Traynor Capital Management, Inc. | 11,965 | $4.69M | 0.27% | +290+2.5% | Added |
| GWM Advisors LLC | 11,718 | $4.59M | 0.02% | −211−1.8% | Reduced |
| Kayne Anderson Rudnick Investment Management LLC | 11,619 | $4.55M | 0.01% | −394−3.3% | Reduced |
| New Mexico Educational Retirement Board | 11,600 | $4.54M | 0.14% | −400−3.3% | Reduced |
| Verition Fund Management LLC | 11,544 | $4.52M | 0.03% | −11,698−50.3% | Reduced |
| United Capital Financial Advisers, LLC | 11,512 | $4.51M | 0.03% | −1,610−12.3% | Reduced |
| Stenger Family Office, LLC | 10,721 | $4.50M | 0.95% | +10,721 | New |
| Two Sigma Advisers, LP | 11,500 | $4.50M | 0.01% | +10,600+1,177.8% | Added |
| PKO Investment Management Joint-Stock Co | 11,500 | $4.50M | 0.38% | −2,000−14.8% | Reduced |
| Slow Capital, Inc. | 11,300 | $4.43M | 0.52% | −514−4.4% | Reduced |
| Callan Family Office, LLC | 11,205 | $4.39M | 0.14% | −5,510−33.0% | Reduced |
| Machina Capital S.A.S. | 11,167 | $4.37M | 0.77% | +11,167 | New |
| AG2R la Mondiale Gestion D'Actifs | 9,788 | $4.36M | 0.22% | 00.0% | Unchanged |
| GAM Holding AG | 11,015 | $4.31M | 0.27% | +462+4.4% | Added |
| Ci Investments Inc. | 10,991 | $4.30M | 0.02% | −2,137−16.3% | Reduced |
| Voleon Capital Management LP | 10,830 | $4.24M | 0.10% | +8,137+302.2% | Added |
| Federation des caisses Desjardins du Quebec | 10,817 | $4.24M | 0.02% | +2,779+34.6% | Added |
| Mark Sheptoff Financial Planning, LLC | 10,771 | $4.22M | 2.02% | 00.0% | Unchanged |
| Siemens Fonds Invest GmbH | 10,742 | $4.21M | 0.23% | −173−1.6% | Reduced |
| BI Asset Management Fondsmaeglerselskab A/S | 10,602 | $4.15M | 0.04% | −3,075−22.5% | Reduced |
| Channel Wealth LLC | 10,559 | $4.14M | 1.11% | −3,318−23.9% | Reduced |
| E. Ohman J:or Asset Management AB | 10,520 | $4.12M | 0.10% | 00.0% | Unchanged |
| Benjamin Edwards Inc | 10,496 | $4.11M | 0.05% | +862+8.9% | Added |
| Generali Investments CEE, investicni spolecnost, a.s. | 10,491 | $4.11M | 0.31% | 00.0% | Unchanged |
| Landscape Capital Management, L.L.C. | 10,484 | $4.11M | 0.26% | +7,405+240.5% | Added |
| Shorepoint Capital Partners LLC | 10,405 | $4.07M | 0.81% | +10,405 | New |
| Joseph Group Capital Management | 10,368 | $4.06M | 1.15% | +2,608+33.6% | Added |
| Brinker Capital Investments, LLC | 10,348 | $4.05M | 0.03% | −993−8.8% | Reduced |
| Morse Asset Management, Inc | 10,305 | $4.04M | 0.81% | +18+0.2% | Added |
| Kestra Private Wealth Services, LLC | 10,254 | $4.02M | 0.05% | +4,127+67.4% | Added |
| Jump Financial, LLC | 10,183 | $3.99M | 0.05% | −3,109−23.4% | Reduced |
| Synovus Financial Corp | 10,162 | $3.98M | 0.05% | +385+3.9% | Added |
| Exchange Traded Concepts, LLC | 10,151 | $3.98M | 0.04% | +7,565+292.5% | Added |
| Sigma Investment Counselors Inc | 10,139 | $3.97M | 0.21% | +840+9.0% | Added |
| Banque Cantonale Vaudoise | 10,122 | $3.96M | 0.15% | −407−3.9% | Reduced |
| Fayez Sarofim & Co | 10,058 | $3.94M | 0.01% | −300−2.9% | Reduced |
| Keybank National Association | 10,039 | $3.93M | 0.01% | −639−6.0% | Reduced |
| Parsons Capital Management Inc | 9,886 | $3.87M | 0.22% | −542−5.2% | Reduced |
| F/M Investments LLC | 9,764 | $3.82M | 0.15% | −19,534−66.7% | Reduced |
| Little House Capital LLC | 9,760 | $3.82M | 0.88% | +3,930+67.4% | Added |
| Cumberland Partners Ltd | 9,744 | $3.82M | 0.25% | −36,826−79.1% | Reduced |
| Baker Chad R | 9,740 | $3.81M | 0.66% | 00.0% | Unchanged |
| Pinnacle Financial Partners Inc | 9,719 | $3.81M | 0.09% | +102+1.1% | Added |
| XTX Topco Ltd | 9,690 | $3.79M | 0.20% | +5,165+114.1% | Added |
| Tema ETFs LLC | 9,651 | $3.78M | 0.31% | +1,583+19.6% | Added |
| Zions Bancorporation, National Association | 9,638 | $3.77M | 0.19% | +9,452+5,081.7% | Added |
| Meiji Yasuda Asset Management Co Ltd. | 9,500 | $3.72M | 0.18% | −133−1.4% | Reduced |
| Empirical Finance, LLC | 9,493 | $3.72M | 0.18% | +487+5.4% | Added |
| Vestmark Advisory Solutions, Inc. | 9,428 | $3.69M | 0.07% | +665+7.6% | Added |
| Howe & Rusling Inc | 9,350 | $3.66M | 0.25% | −94−1.0% | Reduced |
| Allstate Corp | 9,292 | $3.64M | 0.08% | +9,292 | New |
| Horizon Investments, LLC | 9,194 | $3.60M | 0.05% | +1,352+17.2% | Added |
| Crestwood Advisors Group LLC | 9,151 | $3.58M | 0.06% | −892−8.9% | Reduced |
| Bulltick Wealth Management, LLC | 9,102 | $3.56M | 0.84% | +7+0.1% | Added |
| Miracle Mile Advisors, LLC | 9,075 | $3.55M | 0.05% | +1,040+12.9% | Added |
| Sepio Capital, LP | 9,063 | $3.55M | 0.21% | +716+8.6% | Added |
| Tokio Marine Asset Management Co Ltd | 8,956 | $3.51M | 0.12% | +215+2.5% | Added |
| Howard Capital Management Inc. | 8,914 | $3.49M | 0.05% | −40.0% | Reduced |
| Group One Trading, L.P. | 8,889 | $3.48M | 0.10% | +3,037+51.9% | Added |
| Banque Pictet & Cie SA | 8,858 | $3.47M | 0.03% | −8,079−47.7% | Reduced |
| Strategic Advisors LLC | 8,854 | $3.47M | 0.56% | +4,272+93.2% | Added |
| Bensler, LLC | 8,836 | $3.46M | 0.36% | +41+0.5% | Added |
| Davidson Capital Management Inc. | 8,795 | $3.44M | 0.77% | +1,571+21.7% | Added |
| Vinva Investment Management Ltd | 8,635 | $3.41M | 0.07% | −1,710−16.5% | Reduced |
| FIL Ltd | 8,706 | $3.41M | 0.00% | −12,408−58.8% | Reduced |
| HB Wealth Management, LLC | 8,680 | $3.40M | 0.02% | −1,903−18.0% | Reduced |
| Mediolanum International Funds Ltd | 8,544 | $3.38M | 0.04% | +3,050+55.5% | Added |
| Commerzbank Aktiengesellschaft | 8,575 | $3.36M | 0.07% | −1,275−12.9% | Reduced |
| Bessemer Group Inc | 8,459 | $3.31M | 0.01% | +994+13.3% | Added |
| Linden Thomas Advisory Services, LLC | 8,419 | $3.30M | 0.33% | +258+3.2% | Added |