Edgewise Therapeutics, Inc.
EWTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001710072
In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Edgewise Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- +28 vs. Q3 2025
- Shares held
- 121.8M
- +10.9M (+9.8%) vs. Q3 2025
- Total value
- $3.02B
- +$1.22B (+68.0%) vs. Q3 2025
- New holders
- 48
- 69 more added
- Sold out
- 20
- 54 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 226 | $4.82B |
| Q1 2026 | 214 | $3.72B |
| Q4 2025 | 199 | $3.02B |
| Q3 2025 | 173 | $1.82B |
| Q2 2025 | 179 | $1.56B |
| Q1 2025 | 193 | $2.32B |
| Q4 2024 | 201 | $2.64B |
| Q3 2024 | 177 | $2.71B |
| Q2 2024 | 140 | $1.83B |
| Q1 2024 | 129 | $1.67B |
| Q4 2023 | 116 | $871.4M |
| Q3 2023 | 85 | $392.2M |
| Q2 2023 | 95 | $538.8M |
| Q1 2023 | 85 | $443.1M |
| Q4 2022 | 90 | $594.1M |
| Q3 2022 | 94 | $633.5M |
| Q2 2022 | 78 | $405.7M |
| Q1 2022 | 72 | $523.5M |
| Q4 2021 | 58 | $769.4M |
| Q3 2021 | 48 | $795.8M |
| Q2 2021 | 46 | $1.03B |
| Q1 2021 | 31 | $1.48B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Voya Investment Management LLC | 39,648 | $983.9K | 0.00% | +27,231+219.3% | Added |
| State of Wisconsin Investment Board | 39,997 | $992.5K | 0.00% | +3,378+9.2% | Added |
| Prelude Capital Management, LLC | 41,584 | $1.03M | 0.08% | −7,621−15.5% | Reduced |
| Silverarc Capital Management, LLC | 42,052 | $1.04M | 0.15% | +42,052 | New |
| Moody Aldrich Partners LLC | 43,134 | $1.07M | 0.20% | −39,807−48.0% | Reduced |
| Franklin Resources Inc | 43,145 | $1.07M | 0.00% | −5,075−10.5% | Reduced |
| California State Teachers Retirement System | 50,392 | $1.25M | 0.00% | −401−0.8% | Reduced |
| Two Sigma Investments, LP | 50,848 | $1.26M | 0.00% | +24,582+93.6% | Added |
| Legal & General Group Plc | 52,747 | $1.31M | 0.00% | −3,194−5.7% | Reduced |
| HighMark Wealth Management LLC | 53,179 | $1.32M | 0.54% | 00.0% | Unchanged |
| XTX Topco Ltd | 55,620 | $1.38M | 0.04% | +55,620 | New |
| Price T Rowe Associates Inc | 57,315 | $1.42M | 0.00% | +5,929+11.5% | Added |
| Ishara Investments LP | 58,000 | $1.44M | 1.68% | +58,000 | New |
| Schonfeld Strategic Advisors LLC | 59,326 | $1.47M | 0.01% | +7,337+14.1% | Added |
| DekaBank Deutsche Girozentrale | 80,000 | $1.56M | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 70,196 | $1.74M | 0.00% | +24,561+53.8% | Added |
| Invesco Ltd. | 75,438 | $1.87M | 0.00% | +9,382+14.2% | Added |
| Wells Fargo & Company | 75,442 | $1.87M | 0.00% | +33,246+78.8% | Added |
| Jump Financial, LLC | 79,915 | $1.98M | 0.02% | −910−1.1% | Reduced |
| Federated Hermes, Inc. | 82,096 | $2.04M | 0.00% | +22,840+38.5% | Added |
| Rhumbline Advisers | 85,075 | $2.11M | 0.00% | −19,754−18.8% | Reduced |
| Alps Advisors Inc | 86,929 | $2.16M | 0.01% | +35,817+70.1% | Added |
| SG Americas Securities, LLC | 88,723 | $2.20M | 0.00% | +78,842+797.9% | Added |
| New York State Common Retirement Fund | 88,937 | $2.21M | 0.00% | +5,500+6.6% | Added |
| ADAR1 Capital Management, LLC | 90,999 | $2.26M | 0.17% | +50,999+127.5% | Added |
| UBS Asset Management Americas Inc | 98,063 | $2.43M | 0.00% | −41,049−29.5% | Reduced |
| Exome Asset Management LLC | 100,046 | $2.48M | 1.23% | −73,393−42.3% | Reduced |
| Swiss National Bank | 103,900 | $2.58M | 0.00% | +2,000+2.0% | Added |
| Quantum Private Wealth, LLC | 106,024 | $2.63M | 0.77% | +150+0.1% | Added |
| Wellington Management Group LLP | 111,387 | $2.76M | 0.00% | −3,144−2.7% | Reduced |
| Jain Global LLC | 113,856 | $2.83M | 0.03% | +113,856 | New |
| Citadel Advisors LLC | 123,097 | $3.05M | 0.00% | +100,780+451.6% | Added |
| Millennium Management LLC | 126,436 | $3.14M | 0.00% | −598,989−82.6% | Reduced |
| Neuberger Berman Group LLC | 127,136 | $3.15M | 0.00% | −92,510−42.1% | Reduced |
| KVP Capital Advisors, LP | 133,000 | $3.30M | 3.41% | +133,000 | New |
| Schroder Investment Management Group | 145,286 | $3.57M | 0.00% | −5,776−3.8% | Reduced |
| JPMorgan Chase & Co | 146,038 | $3.62M | 0.00% | +77,318+112.5% | Added |
| Balyasny Asset Management LLC | 151,905 | $3.77M | 0.01% | +151,905 | New |
| DAFNA Capital Management LLC | 159,736 | $3.96M | 0.92% | −54,000−25.3% | Reduced |
| Nuveen, LLC | 169,466 | $4.21M | 0.00% | −3,241−1.9% | Reduced |
| HighVista Strategies LLC | 171,137 | $4.25M | 1.09% | −36,964−17.8% | Reduced |
| Ally Bridge Group (NY) LLC | 195,000 | $4.84M | 7.68% | +195,000 | New |
| Bank of New York Mellon Corp | 198,614 | $4.93M | 0.00% | −5,628−2.8% | Reduced |
| Ameriprise Financial Inc | 202,297 | $5.02M | 0.00% | +202,297 | New |
| Deutsche Bank AG | 214,769 | $5.33M | 0.00% | +59,873+38.7% | Added |
| Citigroup Inc | 223,294 | $5.54M | 0.00% | −315,159−58.5% | Reduced |
| Woodline Partners LP | 224,192 | $5.56M | 0.02% | +20.0% | Added |
| Granahan Investment Management Inc | 232,295 | $5.76M | 0.25% | −107,322−31.6% | Reduced |
| Sio Capital Management, LLC | 237,481 | $5.89M | 0.98% | −69,700−22.7% | Reduced |
| Kennedy Capital Management, Inc. | 241,509 | $5.99M | 0.13% | −9,113−3.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 271,385 | $6.73M | 0.01% | +138,882+104.8% | Added |
| Qube Research & Technologies Ltd | 296,208 | $7.35M | 0.01% | −259,505−46.7% | Reduced |
| Eversept Partners, LP | 337,340 | $8.37M | 0.47% | −164,894−32.8% | Reduced |
| Squadron Capital Management LLC | 350,000 | $8.69M | 3.88% | +350,000 | New |
| StemPoint Capital LP | 360,876 | $8.96M | 1.54% | +360,876 | New |
| Barclays PLC | 372,738 | $9.25M | 0.00% | +138,088+58.8% | Added |
| D. E. Shaw & Co., Inc. | 394,695 | $9.79M | 0.01% | −282,866−41.7% | Reduced |
| Parkman Healthcare Partners LLC | 427,690 | $10.6M | 1.01% | −122,483−22.3% | Reduced |
| Sofinnova Investments, Inc. | 437,819 | $10.9M | 0.47% | −82,421−15.8% | Reduced |
| Opaleye Management Inc. | 500,000 | $12.4M | 1.64% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 501,214 | $12.4M | 0.06% | +280,055+126.6% | Added |
| Northern Trust Corp | 559,649 | $13.9M | 0.00% | −28,233−4.8% | Reduced |
| Eventide Asset Management, LLC | 568,310 | $14.1M | 0.22% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 611,384 | $15.2M | 0.00% | +13,781+2.3% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 640,400 | $15.9M | 0.03% | +640,400 | New |
| Marshall Wace, LLP | 681,921 | $16.9M | 0.02% | +681,921 | New |
| FMR LLC | 692,955 | $17.2M | 0.00% | +439,630+173.5% | Added |
| Artisan Partners Limited Partnership | 704,077 | $17.5M | 0.03% | −14,098−2.0% | Reduced |
| Goldman Sachs Group Inc | 718,372 | $17.8M | 0.00% | +190,545+36.1% | Added |
| Victory Capital Management Inc | 746,562 | $18.5M | 0.01% | +247,916+49.7% | Added |
| Norges Bank | 751,355 | $18.6M | 0.00% | +751,355 | New |
| Deerfield Management Company, L.P. (Series C) | 765,694 | $19.0M | 0.24% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 821,940 | $20.4M | 0.03% | +202,062+32.6% | Added |
| Soleus Capital Management, L.P. | 910,000 | $22.6M | 0.96% | +910,000 | New |
| Alliancebernstein L.P. | 1,036,170 | $25.7M | 0.01% | +958,910+1,241.1% | Added |
| American Century Companies Inc | 1,186,467 | $29.4M | 0.01% | +90,994+8.3% | Added |
| Dimensional Fund Advisors LP | 1,213,657 | $30.1M | 0.01% | +30,521+2.6% | Added |
| Bank of America Corp | 1,474,797 | $36.6M | 0.00% | +1,153,665+359.2% | Added |
| Integral Health Asset Management, LLC | 1,500,000 | $37.2M | 1.89% | 00.0% | Unchanged |
| Bellevue Group AG | 1,528,518 | $37.9M | 0.72% | −1,247,479−44.9% | Reduced |
| First Light Asset Management, LLC | 1,573,701 | $39.1M | 2.99% | +158,707+11.2% | Added |
| MPM Oncology Impact Management LP | 1,655,256 | $41.1M | 4.70% | −65,485−3.8% | Reduced |
| State Street Corp | 1,717,343 | $42.6M | 0.00% | +17,434+1.0% | Added |
| Geode Capital Management, LLC | 1,746,222 | $43.3M | 0.00% | +28,581+1.7% | Added |
| UBS Group AG | 2,117,073 | $52.5M | 0.01% | +2,002,945+1,755.0% | Added |
| Morgan Stanley | 2,910,881 | $72.2M | 0.00% | +2,041,203+234.7% | Added |
| Cormorant Asset Management, LP | 3,285,000 | $81.5M | 4.62% | −725,000−18.1% | Reduced |
| Driehaus Capital Management LLC | 4,191,193 | $104.0M | 0.71% | +1,962,908+88.1% | Added |
| Perceptive Advisors LLC | 4,457,974 | $110.6M | 2.03% | +662,080+17.4% | Added |
| Siren, L.L.C. | 4,529,990 | $112.4M | 3.35% | +632,891+16.2% | Added |
| Janus Henderson Group PLC | 4,566,850 | $113.3M | 0.05% | −412,481−8.3% | Reduced |
| Vanguard Group Inc | 4,871,624 | $120.9M | 0.00% | +67,683+1.4% | Added |
| Braidwell LP | 5,210,831 | $129.3M | 4.14% | 00.0% | Unchanged |
| Novo Holdings A/S | 5,350,000 | $132.8M | 10.31% | 00.0% | Unchanged |
| Paradigm Biocapital Advisors LP | 6,541,210 | $162.3M | 4.35% | +371,079+6.0% | Added |
| Baker Bros. Advisors LP | 6,575,940 | $163.2M | 0.96% | −730,000−10.0% | Reduced |
| BlackRock, Inc. | 6,630,576 | $164.5M | 0.00% | +279,089+4.4% | Added |
| Ra Capital Management, L.P. | 10,428,437 | $258.8M | 2.65% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 15,518,492 | $385.1M | 7.88% | 00.0% | Unchanged |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −431,300−100.0% | Sold out |