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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Edgewise Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
199
+28 vs. Q3 2025
Shares held
121.8M
+10.9M (+9.8%) vs. Q3 2025
Total value
$3.02B
+$1.22B (+68.0%) vs. Q3 2025
New holders
48
69 more added
Sold out
20
54 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 199 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ4 2025: $3.02B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding EWTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd8$00.00%00.0%Unchanged
Essential Partners LLC3$740.00%+3New
IFP Advisors, Inc4$990.00%00.0%Unchanged
CIBC Private Wealth Group, LLC4$990.00%+4New
SageView Advisory Group, LLC11$2730.00%+11New
Bare Financial Services, Inc18$4470.00%+18New
Parkside Financial Bank & Trust35$8690.00%00.0%Unchanged
Comerica Bank35$8900.00%00.0%Unchanged
Allworth Financial LP56$1.39K0.00%+23+69.7%Added
The PNC Financial Services Group, Inc.75$1.86K0.00%+8+11.9%Added
SRS Capital Advisors, Inc.87$2.16K0.00%−19−17.9%Reduced
Versant Capital Management, Inc95$2.36K0.00%00.0%Unchanged
BFSG, LLC100$2.48K0.00%00.0%Unchanged
Rothschild Investment LLC135$3.35K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd152$3.77K0.00%+152New
EverSource Wealth Advisors, LLC156$3.87K0.00%+14+9.9%Added
Fortitude Family Office, LLC160$3.97K0.00%00.0%Unchanged
Optiver Holding B.V.161$4.00K0.00%−307−65.6%Reduced
Smartleaf Asset Management LLC173$4.25K0.00%+146+540.7%Added
Rockefeller Capital Management L.P.182$4.52K0.00%+182New
SBI Securities Co., Ltd.207$5.14K0.00%00.0%Unchanged
Eastern Bank223$5.53K0.00%+223New
Larson Financial Group LLC225$5.58K0.00%+90+66.7%Added
CWM, LLC279$7.00K0.00%+147+111.4%Added
Massmutual Trust Co FSB294$7.30K0.00%−50−14.5%Reduced
Daiwa Securities Group Inc.344$9.00K0.00%00.0%Unchanged
Signaturefd, LLC363$9.01K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.408$10.1K0.00%−39−8.7%Reduced
Sterling Capital Management LLC448$11.1K0.00%+285+174.8%Added
Northwestern Mutual Wealth Management Co489$12.1K0.00%+489New
Parallel Advisors, LLC626$15.5K0.00%+531+558.9%Added
Farther Finance Advisors, LLC659$16.4K0.00%+101+18.1%Added
Caitong International Asset Management Co., Ltd710$17.6K0.00%+710New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.728$18.0K0.00%+207+39.7%Added
Quantbot Technologies LP774$19.2K0.00%+774New
Nisa Investment Advisors, LLC1,162$28.8K0.00%+288+33.0%Added
GAMMA Investing LLC1,354$33.6K0.00%+196+16.9%Added
Winthrop Capital Management, LLC1,377$34.0K0.01%00.0%Unchanged
US Bancorp1,564$38.8K0.00%−728−31.8%Reduced
Tower Research Capital LLC (TRC)1,613$40.0K0.00%−26−1.6%Reduced
Acadian Asset Management LLC1,731$42.0K0.00%+1,731New
Seven Fleet Capital Management LP2,000$49.6K0.03%+2,000New
GF Fund Management Co. Ltd.2,079$51.6K0.00%−187−8.3%Reduced
Amalgamated Bank2,120$53.0K0.00%−401−15.9%Reduced
Bessemer Group Inc2,350$58.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC2,854$70.8K0.00%+550+23.9%Added
Public Employees Retirement Association of Colorado2,849$71.0K0.00%00.0%Unchanged
Cygnus Capital Advisors, LLC3,427$85.0K0.06%+3,427New
Canada Pension Plan Investment Board3,900$96.8K0.00%−600−13.3%Reduced
Mirae Asset Global Investments Co., Ltd.5,145$127.7K0.00%+1,072+26.3%Added
Ameritas Investment Partners, Inc.5,638$139.9K0.00%00.0%Unchanged
Quarry LP5,800$143.9K0.02%+5,800New
Los Angeles Capital Management LLC8,177$152.7K0.00%+8,177New
Russell Investments Group, Ltd.6,494$161.2K0.00%−696−9.7%Reduced
Quest Partners LLC7,143$177.3K0.01%−7,131−50.0%Reduced
Simplex Trading, LLC9,069$225.0K0.01%+1,479+19.5%Added
Lion Point Capital, LP9,100$225.8K1.17%+9,100New
Graham Capital Management, L.P.9,468$234.9K0.01%−9,321−49.6%Reduced
Connecticut Capital Management Group, LLC9,839$244.2K0.23%+9,839New
Rafferty Asset Management, LLC9,849$244.4K0.00%+9,849New
SFMG, LLC10,000$248.2K0.02%00.0%Unchanged
Nomura Holdings Inc10,000$248.2K0.00%+10,000New
VARCOV Co.10,034$249.0K0.10%+10,034New
Royal Bank of Canada10,168$253.0K0.00%−5,527−35.2%Reduced
Guggenheim Capital LLC10,571$262.4K0.00%+10,571New
Virtus Investment Advisers, Inc.11,263$279.5K0.08%+3,883+52.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)11,265$279.5K0.00%+4,402+64.1%Added
KLP Kapitalforvaltning AS11,300$280.4K0.00%+700+6.6%Added
Odyssean, LLC11,753$291.7K0.21%+11,753New
Profund Advisors LLC11,825$293.4K0.01%+16+0.1%Added
Fox Run Management, L.L.C.12,360$306.7K0.05%−8,111−39.6%Reduced
Centiva Capital, LP12,500$310.2K0.02%+12,500New
AQR Capital Management LLC13,746$341.1K0.00%+13,746New
Gsa Capital Partners LLP14,085$350.0K0.03%−99,158−87.6%Reduced
Winton Group Ltd14,184$352.0K0.01%+14,184New
AlphaCentric Advisors LLC14,703$364.9K0.36%+14,703New
Arizona State Retirement System14,937$370.7K0.00%−612−3.9%Reduced
State Board of Administration of Florida Retirement System16,870$418.6K0.00%00.0%Unchanged
ProShare Advisors LLC16,976$421.3K0.00%+1,685+11.0%Added
BNP Paribas Arbitrage, SA17,061$423.4K0.00%+2,764+19.3%Added
China Universal Asset Management Co., Ltd.17,251$428.1K0.03%−1,215−6.6%Reduced
State of New Jersey Common Pension Fund D17,978$446.1K0.00%+17,978New
Y-Intercept (Hong Kong) Ltd18,672$463.3K0.01%−38,628−67.4%Reduced
Police & Firemen's Retirement System of New Jersey18,865$468.1K0.00%00.0%Unchanged
LMR Partners LLP20,000$496.3K0.00%+20,000New
Persistent Asset Partners Ltd21,204$526.2K0.25%+21,204New
Raymond James Financial Inc21,609$536.2K0.00%+8,230+61.5%Added
Creative Planning24,468$607.2K0.00%+6,432+35.7%Added
Optimize Financial Inc27,679$686.9K0.35%+396+1.5%Added
Diadema Partners LP30,000$744.5K0.44%+30,000New
Elmind Capital, LP30,000$744.5K0.22%+30,000New
Intech Investment Management LLC30,389$754.1K0.01%+1,210+4.1%Added
Handelsbanken Fonder AB31,100$772.0K0.00%−7,300−19.0%Reduced
SEI Investments Co31,250$775.5K0.00%−7,845−20.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.31,369$778.4K0.00%+19+0.1%Added
Verition Fund Management LLC33,591$833.6K0.00%+33,591New
Manufacturers Life Insurance Company, The36,759$912.2K0.00%+1,221+3.4%Added
MetLife Investment Management38,291$950.2K0.00%−5,592−12.7%Reduced
Oracle Investment Management Inc38,343$951.5K0.62%+38,343New
Knights of Columbus Asset Advisors LLC38,676$959.7K0.05%+38,676New