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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
280
+14 vs. Q3 2025
Shares held
126.4M
+4.65M (+3.8%) vs. Q3 2025
Total value
$3.17B
+$415.1M (+15.0%) vs. Q3 2025
New holders
61
89 more added
Sold out
47
102 more reduced

7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 280 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ4 2025: $3.17B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding APLS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Quarry LP5,000$125.6K0.02%−11,022−68.8%Reduced
Ensign Peak Advisors, Inc4,747$119.2K0.00%−11,800−71.3%Reduced
Bellevue Group AG4,210$105.8K0.00%+4,210New
Walleye Capital LLC3,955$99.3K0.00%−138,203−97.2%Reduced
US Bancorp3,042$76.4K0.00%+376+14.1%Added
Advisor Group Holdings, Inc.2,730$68.6K0.00%−424−13.4%Reduced
EverSource Wealth Advisors, LLC2,602$65.4K0.00%−2,263−46.5%Reduced
STRS Ohio2,582$64.9K0.00%+4+0.2%Added
GF Fund Management Co. Ltd.2,485$62.4K0.00%−232−8.5%Reduced
KBC Group NV2,313$58.0K0.00%00.0%Unchanged
Jones Financial Companies LLLP2,037$51.2K0.00%00.0%Unchanged
T. Rowe Price Investment Management, Inc.1,974$50.0K0.00%−46,782−96.0%Reduced
Parallel Advisors, LLC1,692$42.5K0.00%−278−14.1%Reduced
Signaturefd, LLC1,489$37.4K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.1,012$25.4K0.00%+1,012New
Allworth Financial LP1,010$25.4K0.00%−1,184−54.0%Reduced
Atlantic Private Wealth, LLC1,000$25.1K0.02%+400+66.7%Added
IFP Advisors, Inc982$24.7K0.00%−127−11.5%Reduced
Leonteq Securities AG895$22.5K0.00%−224−20.0%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.840$21.0K0.00%+246+41.4%Added
Quadrant Capital Group LLC825$20.7K0.00%+656+388.2%Added
EFG International AG788$19.8K0.00%+788New
Sterling Capital Management LLC772$19.4K0.00%+608+370.7%Added
Aster Capital Management (DIFC) Ltd643$16.2K0.01%+88+15.9%Added
Northwestern Mutual Wealth Management Co600$15.1K0.00%−1−0.2%Reduced
Versant Capital Management, Inc573$14.4K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.503$12.6K0.00%−527−51.2%Reduced
Archer Investment Corp500$12.6K0.00%00.0%Unchanged
Sound Income Strategies, LLC621$12.4K0.00%+621New
GAMMA Investing LLC479$12.0K0.00%+249+108.3%Added
Larson Financial Group LLC466$11.7K0.00%+73+18.6%Added
Covestor Ltd419$11.0K0.01%−3,669−89.8%Reduced
Farther Finance Advisors, LLC367$9.22K0.00%+35+10.5%Added
Daiwa Securities Group Inc.369$9.00K0.00%−60−14.0%Reduced
CIBC Private Wealth Group, LLC343$8.62K0.00%−34−9.0%Reduced
Tower Research Capital LLC (TRC)319$8.01K0.00%−7,076−95.7%Reduced
Comerica Bank315$7.91K0.00%−51−13.9%Reduced
TFC Financial Management212$5.33K0.00%+212New
Bessemer Group Inc205$5.00K0.00%+205New
True Wealth Design, LLC189$4.75K0.00%−757−80.0%Reduced
Torren Management, LLC189$4.75K0.00%+189New
ZRC Wealth Management, LLC151$3.79K0.00%+151New
Evelyn Partners Investment Management LLP150$3.77K0.00%00.0%Unchanged
Quent Capital, LLC148$3.72K0.00%−297−66.7%Reduced
SBI Securities Co., Ltd.137$3.44K0.00%+44+47.3%Added
Massmutual Trust Co FSB106$2.66K0.00%−75−41.4%Reduced
Sofos Investments, Inc.100$2.51K0.00%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.97$2.51K0.00%00.0%Unchanged
Brown Brothers Harriman & Co95$2.39K0.00%00.0%Unchanged
Crewe Advisors LLC88$2.21K0.00%00.0%Unchanged
Hughes Financial Services, LLC71$1.78K0.00%+71New
Smartleaf Asset Management LLC60$1.51K0.00%+59+5,900.0%Added
Sachetta, LLC60$1.51K0.00%00.0%Unchanged
TD Private Client Wealth LLC56$1.41K0.00%−38−40.4%Reduced
Nisa Investment Advisors, LLC50$1.26K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.46$1.16K0.00%−82,021−99.9%Reduced
Global Retirement Partners, LLC41$1.03K0.00%+21+105.0%Added
Capital Analysts, LLC57$1.00K0.00%00.0%Unchanged
Sunbelt Securities, Inc.39$9800.00%−45−53.6%Reduced
Atlantic Trust, LLC35$8800.00%−51−59.3%Reduced
SageView Advisory Group, LLC35$8800.00%+35New
Parkside Financial Bank & Trust33$8290.00%−3−8.3%Reduced
Basecamp Wealth Advisors LLC31$7790.00%+31New
Manchester Capital Management LLC28$7040.00%+25+833.3%Added
Turning Point Benefit Group, Inc.27$6780.00%+27New
Bare Financial Services, Inc25$6280.00%+4+19.0%Added
United Financial Planning Group LLC24$6030.00%+24New
Greenline Wealth Management LLC21$5370.00%+21New
South State Corp.15$3770.00%00.0%Unchanged
Ronald Blue Trust, Inc.14$3520.00%+14New
Clearstead Advisors, LLC13$3270.00%−1,706−99.2%Reduced
Umb Bank N A12$3010.00%+12New
Assetmark, Inc10$2510.00%+10New
MV Capital Management, Inc.9$2270.00%+1+12.5%Added
WPG Advisers, LLC5$1260.00%00.0%Unchanged
Rothschild Investment LLC4$1000.00%−8−66.7%Reduced
Fideuram - Intesa Sanpaolo Private Banking S.P.A.4$1000.00%+4New
Dunhill Financial, LLC2$530.00%+2New
Transamerica Financial Advisors, Inc.1$250.00%−2−66.7%Reduced
Capital Advisors, Ltd. LLC1$00.00%−135−99.3%Reduced
EcoR1 Capital, LLC0$00.00%−3,447,156−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−903,500−100.0%Sold out
Readystate Asset Management LP0$00.00%−241,977−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−130,828−100.0%Sold out
Worldquant Millennium Advisors LLC0$00.00%−111,979−100.0%Sold out
Bleakley Financial Group, LLC0$00.00%−79,305−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−75,000−100.0%Sold out
J. Safra Sarasin Holding AG0$00.00%−70,500−100.0%Sold out
Engineers Gate Manager LP0$00.00%−66,336−100.0%Sold out
Macquarie Group Ltd0$00.00%−65,156−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−53,540−100.0%Sold out
Highland Capital Management, LLC0$00.00%−50,133−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−47,282−100.0%Sold out
Mariner, LLC0$00.00%−43,239−100.0%Sold out
Scientech Research LLC0$00.00%−34,182−100.0%Sold out
Voleon Capital Management LP0$00.00%−32,221−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−31,446−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−27,223−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−25,500−100.0%Sold out
PharVision Advisers, LLC0$00.00%−22,291−100.0%Sold out