Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 260
- −2 vs. Q3 2024
- Shares held
- 126.7M
- +8.67M (+7.3%) vs. Q3 2024
- Total value
- $4.04B
- +$639.2M (+18.8%) vs. Q3 2024
- New holders
- 61
- 98 more added
- Sold out
- 63
- 72 more reduced
3 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 12,222,222 | $390.0M | 5.52% | +1,111,111+10.0% | Added |
| EcoR1 Capital, LLC | 11,890,843 | $379.4M | 15.16% | 00.0% | Unchanged |
| Wellington Management Group LLP | 11,800,849 | $376.6M | 0.07% | −3,766,120−24.2% | Reduced |
| Vanguard Group Inc | 10,046,025 | $320.6M | 0.01% | +230,450+2.3% | Added |
| Morgan Stanley | 9,627,227 | $307.2M | 0.02% | +6,237,442+184.0% | Added |
| BlackRock, Inc. | 6,477,989 | $206.7M | 0.00% | +285,621+4.6% | Added |
| State Street Corp | 4,525,155 | $144.4M | 0.01% | +484,294+12.0% | Added |
| Deep Track Capital, LP | 4,274,921 | $136.4M | 5.11% | −125,733−2.9% | Reduced |
| Octagon Capital Advisors LP | 3,006,980 | $96.0M | 16.32% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,816,258 | $89.9M | 3.97% | +649,034+29.9% | Added |
| Jennison Associates LLC | 2,760,404 | $88.1M | 0.05% | +939,289+51.6% | Added |
| UBS Group AG | 2,586,739 | $82.5M | 0.02% | +2,272,055+722.0% | Added |
| FMR LLC | 2,127,665 | $67.9M | 0.00% | −772,589−26.6% | Reduced |
| Braidwell LP | 2,098,866 | $67.0M | 1.99% | −1,026,317−32.8% | Reduced |
| AQR Capital Management LLC | 1,856,442 | $59.2M | 0.08% | +1,039,182+127.2% | Added |
| Geode Capital Management, LLC | 1,838,952 | $58.7M | 0.00% | +28,426+1.6% | Added |
| Deutsche Bank AG | 1,778,377 | $56.7M | 0.02% | +30,867+1.8% | Added |
| Bank of America Corp | 1,680,213 | $53.6M | 0.00% | +705,209+72.3% | Added |
| Polar Capital Holdings Plc | 1,577,175 | $50.3M | 0.28% | +495,175+45.8% | Added |
| Royal Bank of Canada | 1,518,827 | $48.5M | 0.01% | +1,376,832+969.6% | Added |
| Boxer Capital Management, LLC | 1,426,000 | $45.5M | 3.87% | +1,426,000 | New |
| National Bank of Canada | 1,385,600 | $44.2M | 0.06% | +1,385,080+266,361.5% | Added |
| CIBC World Markets Corp | 1,285,300 | $41.0M | 0.24% | +1,285,300 | New |
| Point72 Asset Management, L.P. | 1,267,958 | $40.5M | 0.11% | +1,267,958 | New |
| Norges Bank | 1,086,243 | $34.7M | 0.00% | +18,573+1.7% | Added |
| Toronto Dominion Bank | 997,053 | $31.8M | 0.06% | +971,431+3,791.4% | Added |
| Charles Schwab Investment Management Inc | 996,748 | $31.8M | 0.01% | +40,386+4.2% | Added |
| Ameriprise Financial Inc | 882,801 | $28.2M | 0.01% | +22,507+2.6% | Added |
| Natixis | 870,627 | $27.8M | 0.19% | +870,627 | New |
| BNP Paribas Arbitrage, SA | 850,823 | $27.1M | 0.02% | +691,123+432.8% | Added |
| Suvretta Capital Management, LLC | 793,187 | $25.3M | 0.94% | +793,187 | New |
| Balyasny Asset Management LLC | 744,194 | $23.7M | 0.06% | +744,194 | New |
| Invesco Ltd. | 603,656 | $19.3M | 0.00% | −457−0.1% | Reduced |
| Millennium Management LLC | 575,490 | $18.4M | 0.02% | +498,104+643.7% | Added |
| Victory Capital Management Inc | 562,269 | $17.9M | 0.02% | +150,363+36.5% | Added |
| Northern Trust Corp | 547,276 | $17.5M | 0.00% | +94,174+20.8% | Added |
| Candriam Luxembourg S.C.A. | 539,602 | $17.2M | 0.10% | −140,456−20.7% | Reduced |
| Logos Global Management LP | 500,000 | $16.0M | 1.87% | +500,000 | New |
| Nuveen Asset Management, LLC | 491,107 | $15.7M | 0.00% | +150,384+44.1% | Added |
| Integral Health Asset Management, LLC | 420,000 | $13.4M | 1.19% | +420,000 | New |
| JPMorgan Chase & Co | 411,549 | $13.1M | 0.00% | −3,473,181−89.4% | Reduced |
| Walleye Capital LLC | 394,823 | $12.6M | 0.12% | +292,743+286.8% | Added |
| 683 Capital Management, LLC | 360,000 | $11.5M | 1.13% | +125,000+53.2% | Added |
| Price T Rowe Associates Inc | 358,578 | $11.4M | 0.00% | −19,878−5.3% | Reduced |
| Pictet Asset Management Holding SA | 347,854 | $11.1M | 0.01% | +49,901+16.7% | Added |
| Voloridge Investment Management, LLC | 345,885 | $11.0M | 0.04% | −468,679−57.5% | Reduced |
| Hudson Bay Capital Management LP | 345,000 | $11.0M | 0.07% | +85,000+32.7% | Added |
| Jefferies Financial Group Inc. | 341,361 | $10.9M | 0.12% | +292,850+603.7% | Added |
| Amundi | 329,582 | $10.9M | 0.00% | +326,604+10,967.2% | Added |
| Bank of New York Mellon Corp | 334,416 | $10.7M | 0.00% | −9,323−2.7% | Reduced |
| MUFG Securities EMEA plc | 298,000 | $9.51M | 0.18% | +298,000 | New |
| Algert Global LLC | 282,285 | $9.01M | 0.21% | +199,874+242.5% | Added |
| Renaissance Technologies LLC | 271,913 | $8.68M | 0.01% | −100,418−27.0% | Reduced |
| Goldman Sachs Group Inc | 242,967 | $7.75M | 0.00% | +47,901+24.6% | Added |
| Rafferty Asset Management, LLC | 241,474 | $7.71M | 0.03% | +37,328+18.3% | Added |
| Fiduciary Trust Co | 229,801 | $7.33M | 0.10% | −6,265−2.7% | Reduced |
| Schroder Investment Management Group | 219,383 | $7.00M | 0.01% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 212,887 | $6.79M | 0.00% | +21,822+11.4% | Added |
| Sphera Funds Management Ltd. | 206,251 | $6.58M | 1.22% | −9,622−4.5% | Reduced |
| Trexquant Investment LP | 203,008 | $6.48M | 0.08% | +203,008 | New |
| Macquarie Group Ltd | 201,067 | $6.42M | 0.01% | +17,778+9.7% | Added |
| Intrinsic Edge Capital Management LLC | 200,000 | $6.38M | 0.87% | +200,000 | New |
| Prudential Financial Inc | 198,060 | $6.32M | 0.01% | −89,700−31.2% | Reduced |
| Rhenman & Partners Asset Management AB | 195,591 | $6.24M | 0.64% | −171,909−46.8% | Reduced |
| Point72 Europe (London) LLP | 192,694 | $6.15M | 0.36% | +192,694 | New |
| Citigroup Inc | 192,161 | $6.13M | 0.01% | +179,999+1,480.0% | Added |
| Cubist Systematic Strategies, LLC | 191,687 | $6.12M | 0.10% | +191,687 | New |
| Woodline Partners LP | 189,477 | $6.05M | 0.04% | +913+0.5% | Added |
| Squarepoint Ops LLC | 166,962 | $5.33M | 0.01% | +76,621+84.8% | Added |
| Barclays PLC | 159,565 | $5.09M | 0.00% | −96,332−37.6% | Reduced |
| Granahan Investment Management Inc | 154,418 | $4.93M | 0.21% | +3,840+2.6% | Added |
| Swiss National Bank | 143,700 | $4.59M | 0.00% | −10,400−6.7% | Reduced |
| PDT Partners, LLC | 137,694 | $4.39M | 0.39% | −7,825−5.4% | Reduced |
| Aquatic Capital Management LLC | 129,209 | $4.12M | 0.11% | +126,809+5,283.7% | Added |
| HSBC Holdings PLC | 127,828 | $4.08M | 0.00% | +9,341+7.9% | Added |
| Ieq Capital, LLC | 126,710 | $4.04M | 0.04% | +118,404+1,425.5% | Added |
| California Public Employees Retirement System | 126,659 | $4.04M | 0.00% | −10,935−7.9% | Reduced |
| Rhumbline Advisers | 125,560 | $4.01M | 0.00% | −295−0.2% | Reduced |
| Voya Investment Management LLC | 123,151 | $3.93M | 0.00% | +35,185+40.0% | Added |
| Capital Fund Management S.A. | 121,433 | $3.87M | 0.04% | −121,801−50.1% | Reduced |
| Exome Asset Management LLC | 119,467 | $3.81M | 2.87% | +19,100+19.0% | Added |
| Steward Partners Investment Advisory, LLC | 115,045 | $3.67M | 0.03% | +2,250+2.0% | Added |
| Old West Investment Management, LLC | 113,623 | $3.63M | 1.47% | +11,220+11.0% | Added |
| Citadel Advisors LLC | 112,423 | $3.59M | 0.00% | −85,710−43.3% | Reduced |
| Edgestream Partners, L.P. | 109,883 | $3.51M | 0.15% | +10,482+10.5% | Added |
| HighVista Strategies LLC | 108,714 | $3.47M | 1.29% | +72,739+202.2% | Added |
| KBC Group NV | 104,287 | $3.33M | 0.01% | +101,655+3,862.3% | Added |
| Banque Pictet & Cie SA | 97,299 | $3.10M | 0.03% | +23,416+31.7% | Added |
| Jane Street Group, LLC | 95,985 | $3.06M | 0.00% | +76,705+397.8% | Added |
| State Board of Administration of Florida Retirement System | 91,818 | $2.93M | 0.01% | 00.0% | Unchanged |
| Cinctive Capital Management LP | 86,991 | $2.78M | 0.15% | +86,991 | New |
| Legal & General Group Plc | 86,771 | $2.77M | 0.00% | −1,192−1.4% | Reduced |
| Marshall Wace, LLP | 85,495 | $2.73M | 0.00% | +63,705+292.4% | Added |
| Bank of Montreal | 80,991 | $2.58M | 0.00% | +41,635+105.8% | Added |
| State of Wisconsin Investment Board | 80,382 | $2.56M | 0.01% | −657−0.8% | Reduced |
| Rock Springs Capital Management LP | 80,000 | $2.55M | 0.10% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 79,097 | $2.52M | 0.00% | −1,900−2.3% | Reduced |
| Bleakley Financial Group, LLC | 73,505 | $2.35M | 0.07% | −5,451−6.9% | Reduced |
| California State Teachers Retirement System | 70,688 | $2.26M | 0.00% | −5,852−7.6% | Reduced |
| Fieldview Capital Management, LLC | 61,405 | $1.96M | 0.30% | +61,405 | New |