Apellis Pharmaceuticals, Inc.
APLSDelisted- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
APLS is no longer listed, so this page shows Q1 2026. 13F filings for later quarters list far fewer holders.
- Institutional holders
- 324
- +49 vs. Q4 2025
- Shares held
- 140.4M
- +25.8M (+22.6%) vs. Q4 2025
- Total value
- $5.56B
- +$2.69B (+93.5%) vs. Q4 2025
- New holders
- 127
- 91 more added
- Sold out
- 78
- 72 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.29B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.05B |
| Q3 2024 | 265 | $3.52B |
| Q2 2024 | 263 | $4.56B |
| Q1 2024 | 302 | $6.97B |
| Q4 2023 | 284 | $7.16B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.81B |
| Q1 2023 | 282 | $7.49B |
| Q4 2022 | 244 | $5.26B |
| Q3 2022 | 250 | $6.67B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.91B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.13B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 13,536,964 | $544.6M | 0.01% | +7,276,851+116.2% | Added |
| Avoro Capital Advisors LLC | 12,222,222 | $491.7M | 4.84% | 00.0% | Unchanged |
| Morgan Stanley | 10,042,399 | $404.0M | 0.02% | +869,395+9.5% | Added |
| State Street Corp | 6,844,990 | $275.4M | 0.01% | +2,231,544+48.4% | Added |
| UBS Group AG | 6,206,681 | $249.7M | 0.04% | +2,020,459+48.3% | Added |
| Vanguard Portfolio Management LLC | 5,404,559 | $217.4M | 0.01% | +5,404,559 | New |
| Pentwater Capital Management LP | 5,250,000 | $211.2M | 1.50% | +5,250,000 | New |
| Vanguard Capital Management LLC | 4,768,944 | $191.9M | 0.00% | +4,768,944 | New |
| Deep Track Capital, LP | 4,532,374 | $182.3M | 3.76% | −3,217,626−41.5% | Reduced |
| Point72 Asset Management, L.P. | 4,183,918 | $168.3M | 0.29% | +3,586,246+600.0% | Added |
| RTW Investments, LP | 3,685,045 | $148.2M | 1.48% | −3,981,719−51.9% | Reduced |
| HBK Investments L P | 3,550,000 | $142.8M | 1.80% | +3,550,000 | New |
| Suvretta Capital Management, LLC | 3,518,471 | $141.5M | 3.84% | −620,955−15.0% | Reduced |
| Millennium Management LLC | 2,256,802 | $90.8M | 0.07% | +1,310,343+138.4% | Added |
| Geode Capital Management, LLC | 2,075,075 | $83.5M | 0.01% | +49,406+2.4% | Added |
| Goldman Sachs Group Inc | 1,980,144 | $79.7M | 0.01% | +1,790,939+946.6% | Added |
| Balyasny Asset Management LLC | 1,917,501 | $77.1M | 0.15% | +1,852,368+2,844.0% | Added |
| Dimensional Fund Advisors LP | 1,338,995 | $53.7M | 0.01% | +1,158,070+640.1% | Added |
| Glazer Capital, LLC | 1,294,196 | $52.1M | 1.11% | +1,294,196 | New |
| TIG Advisors, LLC | 1,252,986 | $50.4M | 2.41% | +1,252,986 | New |
| Toronto Dominion Bank | 1,236,436 | $49.7M | 0.10% | +1,236,436 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 1,202,100 | $48.4M | 0.08% | +1,202,100 | New |
| Bank of America Corp | 1,190,864 | $47.9M | 0.00% | +234,091+24.5% | Added |
| Hudson Bay Capital Management LP | 1,190,416 | $47.9M | 0.29% | +10,588+0.9% | Added |
| FIL Ltd | 1,140,000 | $45.9M | 0.04% | +1,140,000 | New |
| Kryger Capital LLC | 1,100,000 | $44.3M | 3.13% | +1,100,000 | New |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 1,056,000 | $42.5M | 0.58% | +1,056,000 | New |
| Capitolis Liquid Global Markets LLC | 1,013,500 | $40.8M | 0.26% | +1,013,500 | New |
| Woodline Partners LP | 976,175 | $39.3M | 0.15% | +433,194+79.8% | Added |
| Renaissance Technologies LLC | 935,958 | $37.7M | 0.06% | +302,900+47.8% | Added |
| Marshall Wace, LLP | 929,019 | $37.4M | 0.04% | −61,829−6.2% | Reduced |
| Man Group plc | 915,689 | $36.8M | 0.08% | +771,418+534.7% | Added |
| First Trust Advisors LP | 903,637 | $36.4M | 0.03% | +407,690+82.2% | Added |
| JPMorgan Chase & Co | 2,047,927 | $35.0M | 0.00% | +1,890,173+1,198.2% | Added |
| Magnetar Financial LLC | 869,229 | $35.0M | 0.36% | +869,229 | New |
| Alpine Associates Management Inc. | 864,000 | $34.8M | 2.05% | +864,000 | New |
| Kynam Capital Management, LP | 825,000 | $33.2M | 2.11% | −83,607−9.2% | Reduced |
| Oddo BHF Asset Management SAS | 825,000 | $33.2M | 1.31% | +825,000 | New |
| Northern Trust Corp | 738,440 | $29.7M | 0.00% | +41,919+6.0% | Added |
| Weiss Asset Management LP | 700,000 | $28.2M | 0.52% | +700,000 | New |
| Charles Schwab Investment Management Inc | 675,864 | $27.2M | 0.00% | +31,419+4.9% | Added |
| Citigroup Inc | 657,223 | $26.4M | 0.02% | +35,065+5.6% | Added |
| Vanguard Fiduciary Trust Co | 654,922 | $26.3M | 0.01% | +654,922 | New |
| Tudor Investment Corp Et Al | 650,000 | $26.1M | 0.14% | +435,000+202.3% | Added |
| BNP Paribas Arbitrage, SA | 584,192 | $23.5M | 0.02% | +26,601+4.8% | Added |
| Ossiam | 555,953 | $22.4M | 0.39% | +124,174+28.8% | Added |
| Bank of New York Mellon Corp | 524,789 | $21.1M | 0.00% | +252,864+93.0% | Added |
| Two Sigma Investments, LP | 521,965 | $21.0M | 0.02% | −40,396−7.2% | Reduced |
| Principal Financial Group Inc | 499,053 | $20.1M | 0.01% | +499,053 | New |
| Absolute Gestao de Investimentos Ltda. | 450,000 | $18.1M | 2.07% | +450,000 | New |
| Squarepoint Ops LLC | 449,796 | $18.1M | 0.04% | +257,640+134.1% | Added |
| Invesco Ltd. | 437,868 | $17.6M | 0.00% | +211,892+93.8% | Added |
| AQR Capital Management LLC | 427,970 | $17.2M | 0.01% | −1,848,717−81.2% | Reduced |
| LMR Partners LLP | 403,622 | $16.2M | 0.15% | +403,622 | New |
| Verition Fund Management LLC | 400,000 | $16.1M | 0.16% | +400,000 | New |
| Alliancebernstein L.P. | 638,291 | $16.0M | 0.01% | +603,761+1,748.5% | Added |
| Public Sector Pension Investment Board | 366,674 | $14.8M | 0.05% | +366,674 | New |
| Vivaldi Asset Management, LLC | 350,800 | $14.1M | 0.74% | +350,800 | New |
| Susquehanna International Group, LLP | 340,086 | $13.7M | 0.02% | −193,823−36.3% | Reduced |
| Gabelli Funds LLC | 321,200 | $12.9M | 0.09% | +321,200 | New |
| Beck Bode, LLC | 312,841 | $12.6M | 2.13% | +312,841 | New |
| Meteora Capital, LLC | 300,000 | $12.1M | 0.89% | +300,000 | New |
| O'Connor Alternative Investments LLC | 300,000 | $12.1M | 0.63% | +300,000 | New |
| Jump Financial, LLC | 291,488 | $11.7M | 0.17% | +97,612+50.3% | Added |
| Rhumbline Advisers | 275,540 | $11.1M | 0.01% | +158,623+135.7% | Added |
| Janus Henderson Group PLC | 252,130 | $10.1M | 0.00% | +21,810+9.5% | Added |
| 683 Capital Management, LLC | 250,000 | $10.1M | 0.93% | −80,000−24.2% | Reduced |
| Capstone Investment Advisors, LLC | 250,000 | $10.1M | 0.08% | +250,000 | New |
| Wellington Management Group LLP | 249,635 | $10.0M | 0.00% | −12,471,717−98.0% | Reduced |
| Granite Investment Partners, LLC | 231,917 | $9.33M | 0.57% | −95,177−29.1% | Reduced |
| Legal & General Group Plc | 228,255 | $9.18M | 0.00% | +142,766+167.0% | Added |
| Westchester Capital Management, LLC | 227,489 | $9.15M | 0.44% | +227,489 | New |
| Nuveen, LLC | 220,114 | $8.86M | 0.00% | −461,705−67.7% | Reduced |
| Jefferies Financial Group Inc. | 219,000 | $8.81M | 0.11% | +210,282+2,412.0% | Added |
| Bank of Montreal | 215,041 | $8.65M | 0.00% | +38,470+21.8% | Added |
| Sphera Funds Management Ltd. | 214,914 | $8.65M | 1.49% | −36,047−14.4% | Reduced |
| Trexquant Investment LP | 205,219 | $8.26M | 0.06% | +10,627+5.5% | Added |
| Gabelli & Co Investment Advisers, Inc. | 200,600 | $8.07M | 1.20% | +200,600 | New |
| Pictet Asset Management Holding SA | 426,821 | $7.56M | 0.01% | +35,937+9.2% | Added |
| D. E. Shaw & Co., Inc. | 186,853 | $7.52M | 0.01% | −262,823−58.4% | Reduced |
| Ameriprise Financial Inc | 183,578 | $7.39M | 0.00% | −406,019−68.9% | Reduced |
| Boothbay Fund Management, LLC | 183,522 | $7.38M | 0.17% | +162,107+757.0% | Added |
| Rafferty Asset Management, LLC | 180,471 | $7.26M | 0.03% | +9,015+5.3% | Added |
| Fiduciary Trust Co | 180,161 | $7.25M | 0.09% | −93−0.1% | Reduced |
| UBS Asset Management Americas Inc | 179,953 | $7.24M | 0.00% | +1,065+0.6% | Added |
| Gardner Lewis Asset Management L P | 165,000 | $6.64M | 1.44% | +165,000 | New |
| Rock Springs Capital Management LP | 162,750 | $6.55M | 0.39% | +12,250+8.1% | Added |
| Mackenzie Financial Corp | 153,330 | $6.17M | 0.01% | +57,119+59.4% | Added |
| Picton Mahoney Asset Management | 150,000 | $6.03M | 0.06% | +150,000 | New |
| Swiss National Bank | 149,500 | $6.01M | 0.00% | 00.0% | Unchanged |
| Empowered Funds, LLC | 148,038 | $5.96M | 0.04% | +134,657+1,006.3% | Added |
| CNH Partners LLC | 146,604 | $5.90M | 0.10% | +146,604 | New |
| Chicago Capital Management, LLC | 190,000 | $5.76M | 4.77% | +190,000 | New |
| Slotnik Capital, LLC | 135,000 | $5.43M | 1.61% | +135,000 | New |
| Twin Securities, Inc. | 127,440 | $5.13M | 2.53% | +127,440 | New |
| Royal Bank of Canada | 126,701 | $5.10M | 0.00% | +38,014+42.9% | Added |
| Schonfeld Strategic Advisors LLC | 123,824 | $4.98M | 0.04% | +123,824 | New |
| Quantinno Capital Management LP | 121,270 | $4.88M | 0.01% | +89,507+281.8% | Added |
| Water Island Capital LLC | 120,500 | $4.85M | 0.65% | +120,500 | New |
| Prelude Capital Management, LLC | 111,468 | $4.48M | 0.34% | +72,947+189.4% | Added |